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  1. 42981

    Evaluating the association between lipidome and female reproductive diseases through comprehensive Mendelian randomization analyses by Ye Ma, Fang Wu, Zeming Yu, Lu Yang

    Published 2025-01-01
    “…Furthermore, it was determined that the causal associations between these lipidome profiles and FRDs were independent of BMI, obesity, diabetes, smoking, alcohol use, physical activity, inflammation, depression, waist-hip ratio, vitamin D, dehydroepiandrosterone sulphate, sex hormone binding globulin, and testosterone levels. …”
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  2. 42982
  3. 42983

    Therapeutic drug monitoring and neutralizing anti-drug antibody detection to optimize TNF-alpha inhibitor treatment for uveitis by Howard C. Chen, Jenny Shunyakova, Amit K. Reddy, Srujay Pandiri, Lynn Hassman

    Published 2025-01-01
    “…The primary outcome was success or failure at 12 months, as determined by disease inactivity on steroid-sparing therapy.Results32 patients with suboptimal response to the initial dosing of adalimumab were included. 31.2% (n=10) of patients were found to have neutralizing drug antibodies. …”
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  4. 42984

    Current concepts of chronic gastritis and gastropathies: new international consensus RE.GA.IN by S.M. Tkach, N.V. Kharchenko, A.E. Dorofieiev, Yu.Z. Hurkalo, L.M. Ryzhiy

    Published 2024-12-01
    “…Clinical strategies for the detection and eradication of H.pylori infection were developed, the previously unsuspected clinical and pathological significance of gastric microbiota was established, and extraordinary progress was made in the technology of esophagogastroduodenoscopy. Histolo­gical determination of gastritis in terms of stage (that is, risk stratification of stomach cancer) was implemented into clinical practice. …”
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  5. 42985

    Clinical and microbiological characteristics and prognosis of invasive infection caused by Klebsiella pneumoniae in the community by Hongkui Sun, Hanlin Zhang, Wenqing Lai, Li Lei, Jianwei Li, Miaolian Chen, Haijun Li, Zhanyuan Zhao

    Published 2025-12-01
    “…The risk factors for invasive infection and death due to Kp infection were determined through multivariate logistic regression models and Cox models.Result The mortality rate of community-acquired Klebsiella pneumoniae (cKp) invasive infections markedly exceeded that for non-invasive infections (47.6% vs 25.9%) (p = 0.001). …”
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  6. 42986

    Soluble CD14 Enhances the Response of Periodontal Ligament Stem Cells to Toll-Like Receptor 2 Agonists by Christian Behm, Alice Blufstein, Johannes Gahn, Nazanin Noroozkhan, Andreas Moritz, Xiaohui Rausch-Fan, Oleh Andrukhov

    Published 2019-01-01
    “…Additionally, the effect of different sCD14 concentrations (2.5-250 ng/ml) on the TLR-2 response was determined in Pam3CSK4- or LTA-triggered hPDLSCs. The resulting expression of interleukin- (IL-) 6, chemokine C-X-C motif ligand 8 (CXCL8), and chemokine C-C motif ligand 2 (CCL2) was measured by qPCR and ELISA. …”
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  7. 42987

    Molecular Characterization and Risk Factors of Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae Isolated from Chinese Tertiary Hospital by Zhu R, Li J, Lian S, Li Y, Cai M, Cao Y, Xu X

    Published 2025-01-01
    “…Antimicrobial susceptibility test was used to determine drug resistance. Logistic multivariate regression analysis was conducted to confirm the risk factors for CR-hvKp infection.Results: In total, 239 CRKp isolates were obtained. …”
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  8. 42988

    Dependence of Water Vapour Adsorption on the Polarity of the Graphene Surfaces of Multi-Wall Carbon Nanotubes by Robert H. Bradley, Aurik Andreu, Kelby Cassity, Susan Osbeck, Rodney Andrews, Mark Meier, Colin Johnston

    Published 2010-12-01
    “…The work described herein therefore provides early experimental confirmation of the quantitative role of surface oxygen chemistry in determining the water adsorption character of MWCNT graphene surfaces; it also validates previous simulation studies.…”
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  9. 42989

    Insights into the Mode of Action of Novel Morpholinated Curcumin Derivatives Exhibiting Potent Antitumor Activity in Bladder Cancer Cells In Vitro by Paulina Kobylka, Pawel Bakun, Joanna Kuzminska, Tomasz Goslinski, Marek Murias, Malgorzata Kucinska

    Published 2025-01-01
    “…The anticancer activity of <b>2a</b> and <b>2a-B</b> was determined using MTT (hypoxic conditions) and LDH (normoxic conditions) assays. …”
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  10. 42990

    The prevalence and prognostic significance of Sarcopenia and Adipopenia in Pleural Mesothelioma by Andrew C. Kidd, Gordon W. Cowell, Geoffrey A. Martin, Jenny Ferguson, Dean A. Fennell, Matt Evison, Kevin G. Blyth

    Published 2024-01-01
    “…Introduction: Altered body composition is associated with adverse survival in multiple cancers. We determined the prevalence, prognostic significance and clinicopathological correlates of sarcopenia and adipopenia in Pleural Mesothelioma (PM) patients receiving chemotherapy. …”
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  11. 42991

    Study protocol for COVID-19 breakthrough infections and vaccine-induced immune response among a cohort of healthcare workers, Bangladesh. by Md Zakiul Hassan, Ahamed Khairul Basher, Mohammed Ziaur Rahman, Taufiqur Rahman Bhuiyan, Fahmida Chowdhury, Md Kamal Hossain, Aninda Rahman, Md Nazmul Islam, Lindsey M Duca, Susan Cornelia Kaydos-Daniels, Benjamin A Dahl, Firdausi Qadri, Nancy Ortiz

    Published 2024-01-01
    “…Monitoring emerging SARS-CoV-2 variants and vaccine effectiveness against them is also essential to determine the most effective vaccine options. This study aims to monitor SARS-CoV-2 breakthrough infections, the emergence of new SARS-CoV-2 variants, and host immune response during the peri-infection period of COVID-19. …”
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  12. 42992

    Prognostic role of con-/discordant coronary flow reserve and microvascular resistance in coronary microvascular disease: a systematic review and network meta-analysis by Ibtihal Al Amri, Federico Oliveri, Jin Al-Gully, Jessica Parisa Forouzanfar, Jose Manuel Montero-Cabezas, Johan Wouter Jukema, Melina Cynthia den Haan, Brian Oscar Bingen

    Published 2025-01-01
    “…The aim of this meta-analysis is to characterise the prognostic value and pathophysiological backgrounds of CFR and MR con-/discordance.Methods A systematic search (PROSPERO CRD42024573004) identified studies determining CFR and MR in patients without significant epicardial coronary artery disease. …”
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  13. 42993

    Migration of Health Workers and Its Impacts on the Nigerian Health Care Sector: Protocol for a Scoping Review by David Omiyi, Ebenezer Arubuola, Marcus Chilaka, Md Shafiqur Rahman Jabin

    Published 2025-01-01
    “…ObjectiveThis study aims to comprehensively examine the factors encouraging the emigration of Nigerian health workers, map out the effects of health worker migration on the Nigerian health system, document the loss of investment in health training and education resulting from migration, identify relevant policy initiatives addressing migration, determine the effects of Nigerian health worker migration on destination countries, and identify the benefits and demerits to Nigeria of health worker migration. …”
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  14. 42994

    Genetically predicted causal link between the plasma lipidome and pancreatic diseases: a bidirectional Mendelian randomization study by Liaoyi Lin, Yingbao Huang, Songzan Qian, Lifang Chen, Houzhang Sun

    Published 2025-01-01
    “…BackgroundRecent studies have increasingly emphasized the strong correlation between the lipidome and the risk of pancreatic diseases. To determine causality, a Mendelian randomization (MR) analysis was performed to identify connections between the lipidome and pancreatic diseases.MethodsStatistics from a genome-wide association study of the plasma lipidome, which included a diverse array of 179 lipid species, were obtained from the GeneRISK cohort study with 7,174 participants. …”
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  15. 42995

    Age group analysis of patients with dog bite injuries who visited a single regional emergency medical center and factors affecting wound infections by Dong Ho Kang, Jea Yeon Choi, Woo Sung Choi, Jae Ho Jang, Jin-Seong Cho, Sung Youl Hyun

    Published 2022-06-01
    “…Purpose The aim of this study was to analyze by age group the characteristics of patients with dog bite injuries, as well as determine which factors were associated with wound infections in those patients. …”
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  16. 42996

    The crisis of the concept of society: historiosophical and sociological search by Irena Eglė Laumenskaitė

    Published 1997-12-01
    “…The most realistic problem today that sociology reflects is the subordination of the two levels of social reality—"social physics" (the reality determined by the causality of material interests) and "social metaphysics" (the reality teleologically organized by definite value orientations and ideas). …”
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  17. 42997

    Measuring serious violence perpetration: comparison of police-recorded and self-reported data in a UK cohort by Rosie Cornish, Alison Teyhan, Kate Tilling, John Macleod, Iain Brennan

    Published 2025-02-01
    “… Introduction Determining risk factors and consequences of serious violence requires accurate measures of violence. …”
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  18. 42998

    Effectiveness of mobile health for exercise promotion on cardiorespiratory fitness after a cancer diagnosis: A systematic review and meta‐analysis by Megan E. Gregory, Weidan Cao, Saurabh Rahurkar, Fadi Haroun, James C. Stock, Sanam M. Ghazi, Daniel Addison

    Published 2024-09-01
    “…Mobile health (mHealth) is an increasingly prevalent strategy for health promotion, but whether it consistently improves cardiorespiratory outcomes after a cancer diagnosis is unknown. We sought to determine the effectiveness of mHealth fitness/physical activity interventions on cardiorespiratory fitness outcomes among cancer patients and survivors. …”
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  19. 42999

    A conceptual model and practical guidance for the development, administration, and evaluation of individualized therapies by Lucie Perillat, Lucie Perillat, Andrew McFadyen, Andrew McFadyen, Andrew McFadyen, Patricia Furlong, James Anderson, James Anderson, James Anderson

    Published 2025-01-01
    “…A significant unresolved question is determining where personalized interventions fall on the research-care continuum and understanding the institutional, regulatory, and ethical implications when custom therapies are classified as research, care, or a mix of both. …”
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  20. 43000

    Population Shrinkage and Spatio-Temporal Changes in Cultivated Land Use Efficiency in China’s Agro-Pastoral Ecotone by Lu Chen, Ning Zhao, Zhixun Zhang, Yun Zhang, Wenjie Zuo, Youshuo Wang, Bin Wu, Monika Stanny, Yuheng Li, Guoming Du

    Published 2025-01-01
    “…The following factors were determined, presented in descending order of the absolute value of influence degree: proportion of the population over 65 years old > multiple cropping index > proportion of cultivated land area > proportion of rural population > average years of education > population change rate. …”
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