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42981
Evaluating the association between lipidome and female reproductive diseases through comprehensive Mendelian randomization analyses
Published 2025-01-01“…Furthermore, it was determined that the causal associations between these lipidome profiles and FRDs were independent of BMI, obesity, diabetes, smoking, alcohol use, physical activity, inflammation, depression, waist-hip ratio, vitamin D, dehydroepiandrosterone sulphate, sex hormone binding globulin, and testosterone levels. …”
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42982
Comparative efficacy of lumbar and pelvic support on pain, disability, and motor control in women with postpartum pelvic girdle pain: a three-armed randomized controlled trial
Published 2025-02-01“…Repeated-measures multivariate analysis of variance (MANOVA) was applied to determine the statistical significance between groups. …”
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42983
Therapeutic drug monitoring and neutralizing anti-drug antibody detection to optimize TNF-alpha inhibitor treatment for uveitis
Published 2025-01-01“…The primary outcome was success or failure at 12 months, as determined by disease inactivity on steroid-sparing therapy.Results32 patients with suboptimal response to the initial dosing of adalimumab were included. 31.2% (n=10) of patients were found to have neutralizing drug antibodies. …”
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42984
Current concepts of chronic gastritis and gastropathies: new international consensus RE.GA.IN
Published 2024-12-01“…Clinical strategies for the detection and eradication of H.pylori infection were developed, the previously unsuspected clinical and pathological significance of gastric microbiota was established, and extraordinary progress was made in the technology of esophagogastroduodenoscopy. Histological determination of gastritis in terms of stage (that is, risk stratification of stomach cancer) was implemented into clinical practice. …”
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42985
Clinical and microbiological characteristics and prognosis of invasive infection caused by Klebsiella pneumoniae in the community
Published 2025-12-01“…The risk factors for invasive infection and death due to Kp infection were determined through multivariate logistic regression models and Cox models.Result The mortality rate of community-acquired Klebsiella pneumoniae (cKp) invasive infections markedly exceeded that for non-invasive infections (47.6% vs 25.9%) (p = 0.001). …”
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42986
Soluble CD14 Enhances the Response of Periodontal Ligament Stem Cells to Toll-Like Receptor 2 Agonists
Published 2019-01-01“…Additionally, the effect of different sCD14 concentrations (2.5-250 ng/ml) on the TLR-2 response was determined in Pam3CSK4- or LTA-triggered hPDLSCs. The resulting expression of interleukin- (IL-) 6, chemokine C-X-C motif ligand 8 (CXCL8), and chemokine C-C motif ligand 2 (CCL2) was measured by qPCR and ELISA. …”
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42987
Molecular Characterization and Risk Factors of Carbapenem-Resistant Hypervirulent Klebsiella pneumoniae Isolated from Chinese Tertiary Hospital
Published 2025-01-01“…Antimicrobial susceptibility test was used to determine drug resistance. Logistic multivariate regression analysis was conducted to confirm the risk factors for CR-hvKp infection.Results: In total, 239 CRKp isolates were obtained. …”
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42988
Dependence of Water Vapour Adsorption on the Polarity of the Graphene Surfaces of Multi-Wall Carbon Nanotubes
Published 2010-12-01“…The work described herein therefore provides early experimental confirmation of the quantitative role of surface oxygen chemistry in determining the water adsorption character of MWCNT graphene surfaces; it also validates previous simulation studies.…”
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42989
Insights into the Mode of Action of Novel Morpholinated Curcumin Derivatives Exhibiting Potent Antitumor Activity in Bladder Cancer Cells In Vitro
Published 2025-01-01“…The anticancer activity of <b>2a</b> and <b>2a-B</b> was determined using MTT (hypoxic conditions) and LDH (normoxic conditions) assays. …”
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42990
The prevalence and prognostic significance of Sarcopenia and Adipopenia in Pleural Mesothelioma
Published 2024-01-01“…Introduction: Altered body composition is associated with adverse survival in multiple cancers. We determined the prevalence, prognostic significance and clinicopathological correlates of sarcopenia and adipopenia in Pleural Mesothelioma (PM) patients receiving chemotherapy. …”
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42991
Study protocol for COVID-19 breakthrough infections and vaccine-induced immune response among a cohort of healthcare workers, Bangladesh.
Published 2024-01-01“…Monitoring emerging SARS-CoV-2 variants and vaccine effectiveness against them is also essential to determine the most effective vaccine options. This study aims to monitor SARS-CoV-2 breakthrough infections, the emergence of new SARS-CoV-2 variants, and host immune response during the peri-infection period of COVID-19. …”
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42992
Prognostic role of con-/discordant coronary flow reserve and microvascular resistance in coronary microvascular disease: a systematic review and network meta-analysis
Published 2025-01-01“…The aim of this meta-analysis is to characterise the prognostic value and pathophysiological backgrounds of CFR and MR con-/discordance.Methods A systematic search (PROSPERO CRD42024573004) identified studies determining CFR and MR in patients without significant epicardial coronary artery disease. …”
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42993
Migration of Health Workers and Its Impacts on the Nigerian Health Care Sector: Protocol for a Scoping Review
Published 2025-01-01“…ObjectiveThis study aims to comprehensively examine the factors encouraging the emigration of Nigerian health workers, map out the effects of health worker migration on the Nigerian health system, document the loss of investment in health training and education resulting from migration, identify relevant policy initiatives addressing migration, determine the effects of Nigerian health worker migration on destination countries, and identify the benefits and demerits to Nigeria of health worker migration. …”
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42994
Genetically predicted causal link between the plasma lipidome and pancreatic diseases: a bidirectional Mendelian randomization study
Published 2025-01-01“…BackgroundRecent studies have increasingly emphasized the strong correlation between the lipidome and the risk of pancreatic diseases. To determine causality, a Mendelian randomization (MR) analysis was performed to identify connections between the lipidome and pancreatic diseases.MethodsStatistics from a genome-wide association study of the plasma lipidome, which included a diverse array of 179 lipid species, were obtained from the GeneRISK cohort study with 7,174 participants. …”
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42995
Age group analysis of patients with dog bite injuries who visited a single regional emergency medical center and factors affecting wound infections
Published 2022-06-01“…Purpose The aim of this study was to analyze by age group the characteristics of patients with dog bite injuries, as well as determine which factors were associated with wound infections in those patients. …”
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42996
The crisis of the concept of society: historiosophical and sociological search
Published 1997-12-01“…The most realistic problem today that sociology reflects is the subordination of the two levels of social reality—"social physics" (the reality determined by the causality of material interests) and "social metaphysics" (the reality teleologically organized by definite value orientations and ideas). …”
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42997
Measuring serious violence perpetration: comparison of police-recorded and self-reported data in a UK cohort
Published 2025-02-01“… Introduction Determining risk factors and consequences of serious violence requires accurate measures of violence. …”
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42998
Effectiveness of mobile health for exercise promotion on cardiorespiratory fitness after a cancer diagnosis: A systematic review and meta‐analysis
Published 2024-09-01“…Mobile health (mHealth) is an increasingly prevalent strategy for health promotion, but whether it consistently improves cardiorespiratory outcomes after a cancer diagnosis is unknown. We sought to determine the effectiveness of mHealth fitness/physical activity interventions on cardiorespiratory fitness outcomes among cancer patients and survivors. …”
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42999
A conceptual model and practical guidance for the development, administration, and evaluation of individualized therapies
Published 2025-01-01“…A significant unresolved question is determining where personalized interventions fall on the research-care continuum and understanding the institutional, regulatory, and ethical implications when custom therapies are classified as research, care, or a mix of both. …”
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43000
Population Shrinkage and Spatio-Temporal Changes in Cultivated Land Use Efficiency in China’s Agro-Pastoral Ecotone
Published 2025-01-01“…The following factors were determined, presented in descending order of the absolute value of influence degree: proportion of the population over 65 years old > multiple cropping index > proportion of cultivated land area > proportion of rural population > average years of education > population change rate. …”
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