Resource Management and Health Service Delivery in Rukungiri Municipality: A Case Study of Rwamahwa Health Center IV. by Ndyamuhak,i Faith

“…The study findings on the influence of material resource management on health service delivery at Rwamahwa Health Center IV Rukungiri Municipality were; that the health center has an adequate stock of drugs and medicines which ease service delivery, the health center has all the basic equipment and facilities in place to ensure better service delivery, the health equipments are well maintained to use provision of services and the health centre has a budget for maintenance to ensure that service delivery is to the desired standards. The study findings on the influence of human resource management on health service delivery at Rwamahwa Health Center IV, Rukungiri Municipality were; the health center has all staffing gaps filled which helps to ensure better service delivery, the health center has a medical doctor in place who delivers services promptly, health staff is facilitated to perform their tasks hence better service delivery in the organization, recruitment of health staff is on merit which leads to better provision of services, and deployment of health staff is on merit which leads to better delivery of services. …”
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Investigating the Effect of Increasing Slump on Compressive Strength of Nominal Mix Concrete. by Aturinda, Shallot

“…The study's findings suggest that controlling slump within optimal ranges is crucial to achieving the desired compressive strength in concrete. Additionally, the results highlight the importance of mix ratio selection in conjunction with slump control to ensure optimal concrete performance. …”
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Factors affecting decision making among nurse managers working in government hospitals by Wubete Abeje, Belachew Tegegne, Zenebe Tefera, Yosef Zenebe, Wondwossen Yimam, Birhanu Desu, Yismaw Andargie, Muluken Amare, Molla Kassa, Mulugeta W/Selassie

“…BackgroundEffective nursing management and leadership are essential for the provision of desired patient care that will contribute to the improvement of any country's health indicators. …”
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Lipopolymers as the Basis of Non-Viral Delivery of Therapeutic siRNA Nanoparticles in a Leukemia (MOLM-13) Model by Panadda Yotsomnuk, Amarnath Praphakar Rajendran, Daniel Nisakar Meenakshi Sundaram, Luis Carlos Morales, Cezary Kucharski, Mohammad Nasrullah, Wanwisa Skolpap, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Hasan Uludağ

“…The quantitative analysis of gene silencing performed by qPCR as well as immunostaining/flow cytometry indicated significant reduction in both FLT3 expression and FLT3 protein after specific siRNA delivery. The desired inhibition of cell growth was attained with both FLT3 and KMT2A::MLLT3 siRNAs, and the combination provided more potent effects in both cell growth and colony formation assays. …”
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A preliminary study of linear accelerator-based spatially fractionated radiotherapy by Young Kyu Lee, Yunji Seol, Byeong Jin Kim, Kyu Hye Choi, Ji Hyun Hong, Chan-beom Park, Sun Hwa Kim, Hyeong Wook Park, Wonjoong Cheon, Young Nam Kang, Byung‑Ock Choi

“…The findings provide insights into optimizing LRT treatment plans, offering a comprehensive quantitative reference for achieving desired dose heterogeneity while maintaining normal tissue protection.…”
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Extracellular Vesicles from Amnion-Derived Mesenchymal Stem Cells Ameliorate Hepatic Inflammation and Fibrosis in Rats by Masatsugu Ohara, Shunsuke Ohnishi, Hidetaka Hosono, Koji Yamamoto, Kohei Yuyama, Hideki Nakamura, Qingjie Fu, Osamu Maehara, Goki Suda, Naoya Sakamoto

“…Therefore, development of anti-inflammatory and antifibrotic therapies is desired. Mesenchymal stem cell- (MSC-) based therapy, which has been extensively investigated in regenerative medicine for various organs, can reportedly achieve therapeutic effect in NASH via paracrine action. …”
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Integrated Three-Dimensional Structural and Petrophysical Modeling for Assessment of CO2 Storage Potential in Gas Reservoir by Syed Yasir Ali Shah, Jiangfeng Du, Sayed Muhammad Iqbal, Linze Du, Umair Khan, Baoyi Zhang, Jingqiang Tan

“…Petrophysical modeling indicated promising reservoir characteristics, that is high porosity and permeability in the desired zone. Three-dimensional property models were generated using sequential Gaussian simulation to represent the distribution of petrophysical properties, for example porosity, permeability, shale volume, and water saturation. …”
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Grain yield and water productivity of maize under deficit irrigation and salt stress: Evidences from field experiment and literatures by Jia Gao, Lin Li, Risheng Ding, Shaozhong Kang, Taisheng Du, Ling Tong, Jian Kang, Wanli Xu, Guangmu Tang

“…Drought and salt stress pose great challenges to global agriculture, yet mild deficit irrigation and salt stress have the potential to enhance water productivity (WP). However, it is not desirable to improve WP by reducing irrigation if it leads to a decrease in yield. …”
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Novel Inhibitors for MDM2-MDM4 E3 Ligase Potently Induce p53-Indepedent Apoptosis in Drug-Resistant Leukemic Cells by Rati Lama, Joseph M. Fose, Diana Martín, Inés G. Muñoz, Eunice S. Wang, Pamela J. Sung, Sherry R. Chemler, Xinjiang Wang

“…Owing to the importance of the E3 ligase of MDM2 in its p53-independent oncogenic activity, inhibitors targeting the E3 ligase activity of MDM2-MDM4 are desirable for p53-mutant cancer cells. Here, we report the development of such inhibitors with pro-apoptotic activity in p53-null leukemic cells. …”
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Serum-derived small extracellular vesicles as biomarkers for predicting pregnancy and delivery on assisted reproductive technology in patients with endometriosis by Ayako Muraoka, Akira Yokoi, Akira Yokoi, Akira Yokoi, Kosuke Yoshida, Kosuke Yoshida, Masami Kitagawa, Bayasula, Mayuko Murakami, Natsuki Miyake, Reina Sonehara, Tomoko Nakamura, Satoko Osuka, Hiroaki Kajiyama

“…IntroductionEndometriosis can cause of infertility, and evaluation methods for predicting clinical pregnancy outcomes are desired. Extracellular vesicles (EVs) exist in blood and it contains small non-coding RNAs (ncRNAs) that may reflect disease severity. …”
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Observational cohort study of a group-based VR program to improve mental health and wellbeing in people with life-threatening illnesses by Hannes Kettner, Hannes Kettner, David R. Glowacki, David R. Glowacki, Justin Wall, Justin Wall, Justin Wall, Robin L. Carhart-Harris, Robin L. Carhart-Harris, Leor Roseman, Leor Roseman, Joseph L. Hardy, Joseph L. Hardy

“…Novel approaches that could provide some of the benefits of psychedelic experiences, while avoiding associated challenges, would therefore be highly desirable for supporting the mental wellbeing of people with LTIs. …”
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Patient centered medication treatment for opioid use disorder in rural Vermont: a qualitative study by Emily G. Hichborn, Owen B. Murray, Eilis I. Murphy, Tess E. Gallant, Sarah K. Moore, Bethany M. McLeman, John Saroyan, Anthony Folland, Megan Mitchell, Lisa A. Marsch

“…Prioritizing alliance with patients, adapting care to patient needs and preferences particularly when scheduling, including patients in medication decisions, and biopsychosocial attention to patients are congruent with patient perception of desirable MOUD care. Having this understanding of an established, leading MOUD treatment system may serve to benefit states looking to implement this model, or for states who are looking to improve the model they already have in place, potentially leading to higher treatment and retention rates. …”
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CD44-Receptors-Mediated Multiprong Targeting Strategy Against Breast Cancer and Tumor-Associated Macrophages: Design, Optimization, Characterization, and Cytologic Evaluation by Hussain Z, Abdulrahim Abdul Moti L, Jagal J, Thu HE, Khan S, Kazi M

“…For selective targeting through CD44-receptors that are heavily expressed on the BC cells and TAMs, the fabricated NPs (PTX-TMX-CS-NPs) were functionalized with hyaluronic acid (HA) as a targeting ligand.Results: The optimized HA-PTX-TMX-CS-NPs exhibited desired physicochemical properties (PS ~230 nm, PDI 0.30, zeta potential ~21.5 mV), smooth spherical morphology, high encapsulation efficiency (PTX ~72% and TMX ~97%), good colloidal stability, and biphasic release kinetics. …”
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Establishment of a rapid and quantitative method for detecting the range of infection exposure in preclinical dental education by Ayaka Ueda, Yuki Shinoda-Ito, Kazu Takeuchi-Hatanaka, Takashi Ito, Shintaro Ono, Kimito Hirai, Kazuhiro Omori, Tadashi Yamamoto, Shogo Takashiba

“…Thus, the rapid and inexpensive detection system to detect and measure dental practice-related infection spread during preclinical treatment is highly desired for dental education. This study aimed to establish a method to quantify and visualize infected areas using dental phantoms for safe and effective preclinical dental practices. …”
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Identification of apple genes <i>Md-Exp7</i> and <i>Md-PG1</i> alleles in advanced selections resistant to scab by I. I. Suprun, S. V. Tokmakov, E. A. Al-Nakib, E. V. Lobodina

“…Within the 256 breeding selections samples that have the most priority for breeding alleles of the desired genes in combination with the Rvi6 gene and/or with selection-priority allelic variants of the Md-ACS-1 gene were identified. …”
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Metrics for Evaluating Telemedicine in Randomized Controlled Trials: Scoping Review by Yuka Sugawara, Yosuke Hirakawa, Masao Iwagami, Ryota Inokuchi, Rie Wakimizu, Masaomi Nangaku

“…Moreover, standardization of the evaluation metrics is desired for future clinical trials and studies. …”
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Prevalence, Indications, and Community Perceptions of Caesarean Section Delivery in Ngora District, Eastern Uganda: Mixed Method Study by Isaac Waniala, Sandra Nakiseka, Winnie Nambi, Isaac Naminya, Margret Osuban Ajeni, Jacob Iramiot, Rebecca Nekaka, Julius Nteziyaremye

“…Although facility based, the rate is higher than the desired 5–15%. It is higher than the projected increase of 36% by 2021. …”
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Prediksi Stok dan Pengaturan Tata Letak Barang Menggunakan Kombinasi Algoritma Triple Exponential Smoothing dan FP-Growth by Kristoko Dwi Hartomo, Sri Yulianto Prasetyo, Rahmat Abadi Suharjo

“…Use of information to recognize and understand consumer needs and desires. By overcoming it, the purpose of the research is to regulate the procedures for goods and optimize the preparation of stock items. …”
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Reproducibility and Consistency of Isolation Protocols for Fibroblasts, Smooth Muscle Cells, and Epithelial Cells from the Human Vagina by Jayson Sueters, Rogier Schipperheijn, Judith Huirne, Theo Smit, Zeliha Guler

“…Tissue-engineered solutions carry great potential as an alternative, but cell seeding is desired to prevent complications upon implantation of grafts. …”
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PET imaging of 52Mn labeled DOTATATE and DOTAJR11 by James M. Omweri, Hailey A. Houson, Shannon E. Lynch, Volkan Tekin, Anna G. Sorace, Suzanne E. Lapi

“…Abstract Manganese-52 is gaining interest as an isotope for PET imaging due to its desirable decay and chemical properties for radiopharmaceutical development. …”
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