Cytosolic DNA composition is determined by genomic instability mechanism and regulates dendritic cell-mediated anti-tumor immunity by Shayla R. Mosley, Angie Chen, David N.W. Doell, Siwon Choi, Courtney Mowat, Felix Meier-Stephenson, Vanessa Meier-Stephenson, Kristi Baker

“…Here, we find that cyDNA from MSI CRC cells is inherently more capable of inducing STING activation and improves cytotoxic T cell activation by dendritic cells (DCs). Sequencing indicates that MSI cyDNA is enriched in microsatellites, which, upon DC uptake, induce anti-tumor immunity in a manner consistent with clinical MSI CRCs. …”
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Calreticulin as an Adjuvant In Vivo to Promote Dendritic Cell Maturation and Enhance Antigen-Specific T Lymphocyte Responses against Melanoma by Zheng Gong, Ming Chen, Jie Miao, Chao-Jie Han, Qiao Zhong, Fang-Yuan Gong, Xiao-Ming Gao

“…Previously, we reported that the recombinant CRT fragment 39-272 (CRT/39-272) exhibited superior immunobiological activity, activating macrophages to release cytokines and promoting dendritic cell (DC) maturation. However, the effect of CRT/39-272 in vivo, especially its adjuvant effect on in vivo antitumor immune responses, was not fully investigated. …”
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Hepatitis B e Antigen Seroconversion Is Related with the Function of Dendritic Cells in Chronic Hepatitis B Virus Infection by Chunjing Lin, Hai Zou, Shumin Wang

“…To investigate the relationship between hepatitis B e antigen seroconversion and the function of dendritic cells (DC) in patients with hepatitis B virus. …”
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Saponin-based adjuvant uptake and induction of antigen cross-presentation by CD11b+ dendritic cells and macrophages by Lisa GM Huis in ’t Veld, Lenneke AM Cornelissen, Lune van den Bogaard, Marleen Ansems, Nataschja I Ho, Gosse J Adema

“…Previously, we discovered SBA’s ability to induce cross-presentation in dendritic cells (DCs) leading to CD8+ T cell activation. …”
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Expression of genes of cytokines, transcription factors and differentiation antigens in human dendritic cells activated by double-stranded DNA by A. S. Proskurina, K. E. Orishchenko, E. A. Potter, E. V. Dolgova, A. V. Spaselnikova, G. S. Ritter, N. A. Varaksin, T. G. Ryabicheva, O. Y. Leplina, A. A. Ostanin, E. R. Chernykh, S. S. Bogachev

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CD4+ T Cells Mediate Dendritic Cell Licensing to Promote Multi‐Antigen Anti‐Leukemic Immune Response by Luis Gil‐de‐Gómez, Joseph J. Mattei, Jessica H. Lee, Stephan A. Grupp, Gregor S. D. Reid, Alix E. Seif

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Dysregulated Circulating Dendritic Cell Function in Ulcerative Colitis Is Partially Restored by Probiotic Strain Lactobacillus casei Shirota by Elizabeth R. Mann, Jialu You, Verena Horneffer-van der Sluis, David Bernardo, Hafid Omar Al-Hassi, Jon Landy, Simon T. Peake, Linda V. Thomas, Cheng T. Tee, Gui Han Lee, Ailsa L. Hart, Parveen Yaqoob, Stella C. Knight

“…Background. Dendritic cells regulate immune responses to microbial products and play a key role in ulcerative colitis (UC) pathology. …”
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Mycobacterium tuberculosis Protein Rv3841 Activates Dendritic Cells and Contributes to a T Helper 1 Immune Response by Seunga Choi, Han-Gyu Choi, Ki-Won Shin, Yong Woo Back, Hye-Soo Park, Jae Hwi Lee, Hwa-Jung Kim

“…Here, we studied the action of Rv3841 in maturation of dendritic cells (DCs) and its engagement in the development of T-cell immunity. …”
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PARP-1 Is Critical for Recruitment of Dendritic Cells to the Lung in a Mouse Model of Asthma but Dispensable for Their Differentiation and Function by Laura C. Echeverri Tirado, Mohamed A. Ghonim, Jeffrey Wang, Amir A. Al-Khami, Dorota Wyczechowska, Hanh H. Luu, Hogyoung Kim, Maria Dulfary Sanchez-Pino, José Yélamos, Lina M. Yassin, A. Hamid Boulares

“…Dendritic cells (DCs) are critical in asthma and many other immune diseases. …”
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Molecular Mechanism of VSV-Vectored ASFV Vaccine Activating Immune Response in DCs by Yunyun Ma, Junjun Shao, Wei Liu, Shandian Gao, Guangqing Zhou, Xuefeng Qi, Huiyun Chang

Subjects: “…dendritic cells…”
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Exogenous Interleukin-37 Alleviates Hepatitis with Reduced Dendritic Cells and Induced Regulatory T Cells in Acute Murine Cytomegalovirus Infection by Yufei Ruan, Zhengwang Wen, Ke Chen, Jianan Xi, Bo Wu, Zhiyong Xu, Minzhi Jiang, Junling Zhang, Yiping Chen, Qi Liu

“…In the present study, potential protective effect of exogenous IL-37 on murine cytomegalovirus- (MCMV-) infected hepatitis was evaluated through analyses of serum transaminases, the liver histopathology and cytokine expression, and functional state of dendritic cells (DCs) and regulatory T cells (Tregs). …”
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Flt3/Flt3L Participates in the Process of Regulating Dendritic Cells and Regulatory T Cells in DSS-Induced Colitis by Jing-Wei Mao, Yu-Shuang Huang, Hai-Ying Tang, Jian Bi, Yan-Fei Liu, Ying-De Wang

“…The immunoregulation between dendritic cells (DCs) and regulatory T cells (T-regs) plays an important role in the pathogenesis of ulcerative colitis (UC). …”
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NOD Dendritic Cells Stimulated with Lactobacilli Preferentially Produce IL-10 versus IL-12 and Decrease Diabetes Incidence by Jean N. Manirarora, Sarah A. Parnell, Yoon-Hyeon Hu, Michele M. Kosiewicz, Pascale Alard

“…Dendritic cells (DCs) from NOD mice produced high levels of IL-12 that induce IFNγ-producing T cells involved in diabetes development. …”
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Clinicopathologic profile of intra-abdominal follicular dendritic cell sarcoma: A study of three cases with a literature review by Jianhong Yan, Qi Wu, Yuchang Hu, Ting Nai

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GK-1 Improves the Immune Response Induced by Bone Marrow Dendritic Cells Loaded with MAGE-AX in Mice with Melanoma by Gabriela Piñón-Zárate, Miguel Ángel Herrera-Enríquez, Beatriz Hernández-Téllez, Katia Jarquín-Yáñez, Andrés Eliú Castell-Rodríguez

“…The aim of dendritic cell (DC) vaccination in cancer is to induce tumor-specific effector T cells that may reduce and control tumor mass. …”
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Insulin Modulates Paracoccidioides brasiliensis-Induced Inflammation by Restoring the Populations of NK Cells, Dendritic Cells, and B Lymphocytes in Lungs by Felipe Beccaria Casagrande, Sabrina de Souza Ferreira, Fernanda Peixoto Barbosa Nunes, Lavínia Maria Dal’Mas Romera, Suelen Silvana dos Santos, Fernando Henrique Galvão Tessaro, Paula Regina Knox de Souza, Sandro Rogério Almeida, Joilson Oliveira Martins

“…In addition, diabetic mice presented a reduced influx of TCD4+ cells, TCD8+ cells, B lymphocytes, NK cells, and dendritic cells compared to control infected groups. Insulin treatment restored the leukocyte number in PeLF and restored the presence of B lymphocytes, dendritic cells, and NK cells in lungs of diabetic animals. …”
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Tolerogenic Splenic IDO+ Dendritic Cells from the Mice Treated with Induced-Treg Cells Suppress Collagen-Induced Arthritis by Jie Yang, Yiming Yang, Huahua Fan, Hejian Zou

“…However, the mechanisms whereby transferred iTregs suppress immune responses, particularly the interplay between iTregs and dendritic cells (DCs) in vivo, remain incompletely understood. …”
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Corrigendum to “Immune Suppressive Effects of Tonsil-Derived Mesenchymal Stem Cells on Mouse Bone-Marrow-Derived Dendritic Cells” by Minhwa Park, Yu-Hee Kim, Jung-Hwa Ryu, So-Youn Woo, Kyung-Ha Ryu

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The Human Mesenchymal Stromal Cell-Derived Osteocyte Capacity to Modulate Dendritic Cell Functions Is Strictly Dependent on the Culture System by Sara Trabanelli, Federico La Manna, Marco Romano, Valentina Salvestrini, Michele Cavo, Marilena Ciciarello, Roberto M. Lemoli, Antonio Curti

“…However, a deep characterization of the immunological properties of DOC, including their effect on dendritic cell (DC) function, is not available. DOC can be used either as cellular suspension (detached, Det-DOC) or as adherent cells implanted on scaffolds (adherent, Adh-DOC). …”
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Anti-HMGB1 Neutralizing Antibody Ameliorates Neutrophilic Airway Inflammation by Suppressing Dendritic Cell-Mediated Th17 Polarization by Fang Zhang, Gang Huang, Bo Hu, Li-Ping Fang, E-Hong Cao, Xiao-Feng Xin, Yong Song, Yi Shi

“…We demonstrate that high mobility group box 1 protein (HMGB1) directs Th17 skewing by regulating dendritic cell (DC) function. First, our in vitro studies reveal that recombinant HMGB1 (rHMGB1) activates myeloid DCs to produce IL-23 in vitro, and rHMGB1-activated DCs prime naïve lymphocytes to produce the Th17 cytokine IL-17A. …”
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