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81
Hippocampal Neurogenesis and the Brain Repair Response to Brief Stereotaxic Insertion of a Microneedle
Published 2013-01-01“…This study describes immediate and early humoral and cellular mechanisms of the brain’s response to microinjury that will be useful for the investigation of potential neuroprotective and deleterious effects of deep brain stimulation in various neuropsychiatric disorders.…”
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82
Psychiatric and Behavioral Complications of GPi DBS in an Adolescent with Myoclonus Dystonia
Published 2019-01-01“…Myoclonus dystonia is a rare movement disorder that often causes significant disability. Deep brain stimulation of the internal pallidum (GPi DBS) is a recommended treatment for those who do not respond to pharmacotherapy or who have intolerable side effects. …”
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83
N2GNet tracks gait performance from subthalamic neural signals in Parkinson’s disease
Published 2025-01-01“…Abstract Adaptive deep brain stimulation (DBS) provides individualized therapy for people with Parkinson’s disease (PWP) by adjusting the stimulation in real-time using neural signals that reflect their motor state. …”
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84
Treatment Tactics for Psychosis in Parkinson’s Disease: A Literature Review
Published 2024-12-01“…Non-pharmacological treatment may include electroconvulsive therapy, deep brain stimulation, and transcranial direct current stimulation. …”
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85
Regulatory Mechanism for Absence Seizures in Bidirectional Interactive Thalamocortical Model via Different Targeted Therapy Schemes
Published 2021-01-01“…Regulatory mechanism for absence seizures is further applied to CTMBC via four different targeted therapy schemes, such as deep brain stimulation (DBS), charge-balanced biphasic pulse (CBBP), coordinated reset stimulation (CRS) 1 : 0, and (CRS) 3 : 2. …”
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86
Critical Aspects of Clinical Trial Design for Novel Cell and Gene Therapies
Published 2011-01-01“…Beyond the provision of symptomatic efficacy and safety data, it also remains to be identified whether the possibilities offered by stem cell and gene therapy technological advances might translate to meaningful neuroprotection and/or disease-modifying effects or alleviate the nonmotor aspects of PD and thus offer additional benefits beyond those achieved through conventional pharmacotherapy or deep brain stimulation (DBS).…”
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87
Brain Stimulation Techniques in Research and Clinical Practice: A Comprehensive Review of Applications and Therapeutic Potential in Parkinson’s Disease
Published 2024-12-01“…This review aims to synthesize the current literature on the application of brain stimulation techniques, including non-invasive methods such as transcranial magnetic stimulation (TMS), transcranial electrical stimulation (tES), transcranial focused ultrasound stimulation (tFUS), and transcutaneous vagus nerve stimulation (tVNS), as well as invasive approaches like deep brain stimulation (DBS). We explore the efficacy and safety profiles of these techniques in alleviating both motor impairments, such as bradykinesia and rigidity, and non-motor symptoms, including cognitive decline, depression, and impulse control disorders. …”
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88
Progress on neuromodulation for treatment of rare movement disorders
Published 2025-01-01“…However, the emergence of neuromodulation technique such as deep brain stimulation (DBS), spinal cord stimulation (SCS), transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS) and electroconvulsive therapy (ECT) offers new hope for patients with rare movement disorders. …”
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89
Functional Role of Adult Hippocampal Neurogenesis as a Therapeutic Strategy for Mental Disorders
Published 2012-01-01“…Potential treatments which include electroconvulsive therapy, deep brain stimulation, chemical antidepressants, and exercise therapy are discussed. …”
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90
The Efficacy and Predictors of Using GPi-DBS to Treat Early-Onset Dystonia: An Individual Patient Analysis
Published 2021-01-01“…To compare the efficacy in patients with different genotypes, identify the potential predictive factors, and summarize the complications of globus pallidus deep brain stimulation (GPi-DBS) treating early-onset dystonia. …”
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91
Direct Cost of Parkinson’s Disease: A Real-World Data Study of Second-Line Therapies
Published 2020-01-01“…The aim of this study was to analyse the costs of the following therapies: deep brain stimulation (DBS), continuous duodenal levodopa/carbidopa infusion (CDLCI), and continuous subcutaneous apomorphine infusion (CSAI). …”
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92
Advancing Neuroscience and Therapy: Insights into Genetic and Non-Genetic Neuromodulation Approaches
Published 2025-01-01“…This review categorizes neuromodulation techniques into genetic neuromodulation methods (including optogenetics, chemogenetics, sonogenetics, and magnetogenetics) and non-genetic neuromodulation methods (including deep brain stimulation, transcranial magnetic stimulation, transcranial direct current stimulation, transcranial ultrasound stimulation, photobiomodulation therapy, infrared neuromodulation, electromagnetic stimulation, sensory stimulation therapy, and multi-physical-factor stimulation techniques). …”
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93
Therapeutic Approaches to Tackle the Challenge of Depression That Is Resistant to Treatment–A Narrative Review
Published 2025-01-01“…Nonpharmacological interventions, including brain stimulation such as theta burst stimulation, deep brain stimulation, electroconvulsive therapy, repetitive transcranial magnetic stimulation, intermittent transcranial magnetic stimulation, and magnetic seizure therapy, as well as psychotherapeutic approaches, are being explored for the management of TRD in both present and future contexts. …”
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94
Impact of Duodopa on Quality of Life in Advanced Parkinson's Disease: A UK Case Series
Published 2013-01-01“…Treatment options in advanced Parkinson’s disease (PD) include subcutaneous apomorphine, pallidal or subthalamic nucleus Deep Brain Stimulation (DBS), or levodopa/carbidopa intestinal gel (LCIG/Duodopa). …”
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95
Time series segmentation for recognition of epileptiform patterns recorded via microelectrode arrays in vitro.
Published 2025-01-01“…Approximately 30-40% of patients respond poorly to antiepileptic medications, leading to a significant negative impact on their quality of life. Closed-loop deep brain stimulation (DBS) is a promising treatment for individuals who do not respond to medical therapy. …”
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96
Reverse Visually Guided Reaching in Patients with Parkinson’s Disease
Published 2022-01-01“…Preoperative psychological assessments are used to screen for impulsivity that may be worsened by deep brain stimulation (DBS) of the subthalamic nucleus (STN). …”
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97
Diagnosis, treatment and management of apathy in Parkinson’s disease: a scoping review
Published 2020-09-01“…Future research should aim to detect an ideal screening tool for apathy in PD, to identify the best treatment options for apathy and the variety of comorbidities it may present with and finally aim to better understand postoperative apathy in those with deep brain stimulation.…”
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98
Modeling the modulation of beta oscillations in the basal ganglia by dual-target optogenetic stimulation
Published 2025-01-01“…Optogenetic techniques provide precise control over the activity of specific neurons within the nucleus, offering more accurate regulatory effects compared to deep brain stimulation. The heterogeneity of the globus pallidus externa (GPe) has garnered wide attention, wherein significant differences in pathological changes emphasize its potential as a stimulation target with distinct mechanisms. …”
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99
Balance Dysfunction in Parkinson’s Disease: The Role of Posturography in Developing a Rehabilitation Program
Published 2015-01-01“…The dopaminergic drugs or deep brain stimulation does not always provide significant improvements of BD and rehabilitative approaches have also failed to restore this condition. …”
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100
Application and effect mechanism of electrical nerve stimulation modulation technology in rehabilitation therapy following spinal cord injury
Published 2024-01-01“…The article examines the use of invasive techniques,including spinal cord electrical stimulation (SCS) and deep brain stimulation (DBS),and non-invasive techniques,such as peripheral nerve stimulation (PNS) and transcranial direct current stimulation (tDCS),in the context of post-SCI rehabilitation. …”
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