Advanced glycation end products and risk of mortality in patients with cirrhosis: a prospective cohort study by Mohsen Shaygan Tabar, Maryam Nilghaz, Azita Hekmatdoost, Fereshteh Pashayee-Khamene, Zeinab Mokhtari, Sara Karimi, Saleheh Ahmadzadeh, Mehdi Saberifiroozi, Behzad Hatami, Zahra Yari

“…In addition, along with increasing trend of dietary AGEs, the number of deaths increased significantly (P = 0.024). Higher mortality risk was generally attributed to higher dietary AGEs in patients with cirrhosis.…”
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What makes an epidemic a disaster: the future of epidemics within the EM-DAT International Disaster Database by Margo Tonnelier, Damien Delforge, Regina Below, Juan Armando Torres Munguía, Claude Saegerman, Valentin Wathelet, Joris A. F. van Loenhout, Niko Speybroeck

“…However, they proposed pathogen-based criteria and agreed that disruption to society, especially to the healthcare system, serves as a determinant of epidemic disasters. The experts favored deaths and confirmed cases as key indicators, alongside suggestions on refining EM-DAT's entry criteria and improving epidemic impact assessment. …”
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Legacy and emerging organic pollutants in indoor and outdoor environments in Africa: Contamination levels, health risks, and analytical techniques by Godfrey Muhwezi, Christine Kyarimpa, Ivan Gumula, Christine Betty Nagawa, Solomon Omwoma, Henry Matovu, Julius Matsiko, Silver Odongo, Douglas Sifuna, Ivan Špánik, Charles Drago Kato, Patrick Ssebugere

“…The World Health Organisation reported that over 20 % of the global disease burden and deaths are caused by environmental factors such as air and dust pollution. …”
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Early mortality, epidemiological and clinical factors in seriously ill patients treated in Intermediate Care Units by Osmani Pérez Ortiz, Angel Antonio Urbay Ruíz, Elaine Teresa Gutiérrez Pérez, Lis Marlyn Rodríguez García, Ivette Irene Molina Linares, Ernesto Conyedo Vergel

“…Methods: an observational, analytical, cross-sectional study was carried out at the “Arnaldo Milián Castro” Hospital between October 2019 and October 2022. All deaths (348) in the Intermediate Care Unit in the analyzed period were studied. …”
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Low Hemoglobin among Pregnant Women in Midwives Practice of Primary Health Care, Jatinangor, Indonesia: Iron Deficiency Anemia or β-Thalassemia Trait? by Ari Indra Susanti, Edhyana Sahiratmadja, Gatot Winarno, Adhi Kristianto Sugianli, Herman Susanto, Ramdan Panigoro

“…Low hemoglobin (Hb) or anemia is common among pregnant women in developing countries which may cause adverse pregnancy outcomes and maternal deaths. Our study aimed to assess Hb level measured by midwives in primary health care facility at rural area of Jatinangor, Indonesia, and to explore whether the anemia was due to iron deficiency (IDA) or β-thalassemia trait (β-TT). …”
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Is <i>Punica granatum</i> Efficient Against Sepsis? A Comparative Study of Amifostine Versus Pomegranate by Kazim Sahin, Sena Sahin Aktura, Ilkay Bahceci, Tolga Mercantepe, Levent Tumkaya, Atilla Topcu, Filiz Mercantepe, Omer Faruk Duran, Huseyin Avni Uydu, Zihni Acar Yazici

“…Sepsis causes 11 million deaths annually, a third of which are associated with acute lung injury (ALI). …”
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Transitioning from Oxime to the Next Potential Organophosphorus Poisoning Therapy Using Enzymes by Rauda A. Mohamed, Keat K. Ong, Noor Azilah M. Kasim, Norhana A. Halim, Siti Aminah M. Noor, Victor F. Knight, Nurul Najwa Ab. Rahman, Wan Md Zin W. Yunus

“…An estimated 200,000 acute pesticide poisoning deaths occur each year, many in developing countries. …”
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Opposite outcomes of triglyceride-glucose index and associated cardiovascular mortality risk in type 2 diabetes mellitus participants by different obesity criteria by Hui Huang, Jing Tian, Jiahui Xu, Qingguang Chen, Mengjie Cai, Hao Lu, Fan Gong

“…Over a 9.1-year follow-up, 691 CVD deaths occurred. Among non-obese T2DM participants (BMI-defined), the hazard ration for CVD mortality was 1.73 in the fourth quartile group of TyG index compared with the first quartile group. …”
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The Health Impacts of Air Pollution in the Context of Changing Climate in Africa: A Narrative Review with Recommendations for Action by Lynn M Atuyambe, Raphael E Arku, Natasha Naidoo, Thandi Kapwata, Kwaku Poku Asante, Guéladio Cissé, Belay Simane, Caradee Y Wright, Kiros Berhane

“…Introduction: Despite the broad improvement in air quality, air pollution remains a major leading global risk factor for ill health and deaths each year. Air pollution has a significant impact on both health and economic growth in Africa. …”
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Targeting murine metastatic cancers with cholera toxin A1-adjuvanted peptide vaccines by Sanchari Paul, Mustafa Kaya, Olivia Johnsson, Hanna Grauers Wiktorin, Andreas Törnell, Mohammad Arabpour, Kristoffer Hellstrand, Anna Martner

“…The dissemination of tumor cells with ensuing metastasis is responsible for most cancer-related deaths. Cancer vaccines may, by inducing tumor-specific effector T cells, offer a strategy to eliminate metastasizing tumor cells. …”
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Feasibility and Safety of Pleuroscopic Cryobiopsy of the Pleura: A Prospective Study by Chia-Hung Chen, Wen-Chien Cheng, Biing-Ru Wu, Chih-Yu Chen, Wei-Chun Chen, Wei-Chih Liao, Chih-Yen Tu

“…There were no significant complications or procedure-related deaths. Conclusions. Based on these results, CB during semirigid pleuroscope has a high diagnostic yield, differentiating EPE of unknown etiology with satisfactory effectiveness and safety.…”
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Application and progress of non-invasive imaging in predicting lung invasive non-mucinous adenocarcinoma under the new IASLC grading guidelines by Jinbao Feng, Xiaonan Shao, Jianxiong Gao, Xinyu Ge, Yan Sun, Yunmei Shi, Yuetao Wang, Rong Niu

“…Abstract Lung cancer is the leading cause of cancer-related deaths worldwide, with invasive non-mucinous adenocarcinoma (INMA) being the most common type and carrying a poor prognosis. …”
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Challenges and Frugal Remedies for Lowering Facility Based Neonatal Mortality and Morbidity: A Comparative Study by Hippolite O. Amadi, Akin O. Osibogun, Olateju Eyinade, Mohammed B. Kawuwa, Angela C. Uwakwem, Maryann U. Ibekwe, Peter Alabi, Chinyere Ezeaka, Dada G. Eleshin, Mike O. Ibadin

“…A collaborative outreach was initiated to devise frugal measures that could reduce neonatal deaths in Nigeria. Prevailing issues of concern that could militate against neonatal survival within care centres were identified and remedies were proffered. …”
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Staphylococcus aureus carriage is associated with microbiome composition in the nares and oropharynx, not the hand, of monozygotic twins by Mark R. Dalman, W. Brian Simison, Danny Nielsen, Sabana Bhatta, Noor Ramahi, Clair Yee, Dipendra Thapaliya, Jhalka Kadariya, Shanice Cheatham, Hailee Olson, Tara C. Smith

“…With antibiotic-resistant strains causing 11,000 deaths yearly and ~2% of the population nasally colonized with methicillin-resistant S. aureus, a search for predictive markers and associative relationships between carriage have been long-sought goals. …”
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Dose-Dense Epirubicin and Cyclophosphamide Followed by Docetaxel as Adjuvant Chemotherapy in Node-Positive Breast Cancer by Hamid Reza Mirzaei, Parisa Sabet Rasekh, Fatemeh Nasrollahi, Parto Sabet Rasekh, Zahra Akbari Tirabad, Hamid Reza Moein, Taban Ghaffari Pour, Parastoo Hajian

“…There were two toxicity-related deaths, one patient due to grade 4 febrile neutropenia and the other due to congestive heart failure. …”
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Serum sodium to chloride ratio and mortality on continuous ambulatory peritoneal dialysis: a multicenter retrospective study by Jiayin You, Sijie Gu, Ning Su, Xiaoran Feng, Fenfen Peng, Qingdong Xu, Xiaojiang Zhan, Yueqiang Wen, Xiaoyang Wang, Na Tian, Xianfeng Wu, Niansong Wang

“…Of 3341 patients, 722 patients died, including 259 cardiovascular deaths. Following adjustments for comorbidities and multiple covariates, individuals in the highest Na/Cl quartile (>1.42) exhibited lower all‐cause mortality (hazard ratio [HR] 0.63, 95% confidence interval [CI] 0.47–0.86) and cardiovascular mortality (HR 0.38, 95% CI 0.22–0.67) compared with those in the lowest quartile (<1.33). …”
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Successes and Challenges in an Integrated Tuberculosis/HIV Clinic in a Rural, Resource-Limited Setting: Experiences from Kericho, Kenya by Douglas N. Shaffer, Eunice T. Obiero, Josphat B. Bett, Ignatius N. Kiptoo, Jonah K. Maswai, Fredrick K. Sawe, E. Jane Carter

“…Over 5 years, treatment success rose from 40.0% to 74.6%, lost to follow-up dropped from 36.0% to 12.5%, and deaths fell from 20.0% to 5.4%. For patients starting ART after TB treatment, those with CD4 ≥ 50 cells/mm3 were twice as likely to achieve treatment success (OR=2.0, 95% CI = 1.3–3.1) compared to those with CD4 < 50 cells/mm3. …”
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PSCA-targeted BPX-601 CAR T cells with pharmacological activation by rimiducid in metastatic pancreatic and prostate cancer: a phase 1 dose escalation trial by Mark N. Stein, Ecaterina E. Dumbrava, Benjamin A. Teply, Usama S. Gergis, Martin E. Guiterrez, Ran Reshef, Sumit K. Subudhi, Céline F. Jacquemont, Joseph H. Senesac, J. Henri Bayle, Charity D. Scripture, Monica S. Chatwal, Mehmet A. Bilen, Walter M. Stadler, Carlos R. Becerra

“…Two dose-limiting toxicities and two treatment-related deaths occurred in the highest-dose mCRPC cohort, after which the study was terminated, without determination of the RP2D. …”
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Tuberculosis and drug resistance in a region of Southern Italy among native and foreign-born populations: A twelve-year province-based study by Salvatore Rotundo, Salvatore Nisticò, Helen Linda Morrone, Luigia Gallo, Saveria Dodaro, Carmelo Papola, Pasquale Minchella, Giovanni Matera, Francesca Greco, Luigi Principe, Lorenzo Antonio Surace, Francesco Lucia, Francesca Serapide, Alessandro Russo, Carlo Torti, Enrico Maria Trecarichi

“…Tuberculosis (TB) remains a significant global health challenge, with the World Health Organization (WHO) aiming for a 95% reduction in TB deaths by 2030. Disparities in TB detection persist, particularly regarding gender, immigration status, and resistance patterns. …”
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Early Treatment with Intranasal Neostigmine Reduces Mortality in a Mouse Model of Naja naja (Indian Cobra) Envenomation by Matthew R. Lewin, Stephen P. Samuel, David S. Wexler, Philip Bickler, Sakthivel Vaiyapuri, Brett D. Mensh

“…Objective. Most snakebite deaths occur prior to hospital arrival; yet inexpensive, effective, and easy to administer out-of-hospital treatments do not exist. …”
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