Transcriptome-proteome integration analysis identifies elevated expression of LARP7 promoting the tumorigenesis and development of gastrointestinal stromal tumors by Heng Zheng, Yong Pan

“…The relationship between gene expression and cytokine pathway activation was assessed via CytoSig. …”
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Molecular dynamics simulations reveal key roles of the LIF receptor in the assembly of human LIF signaling complex by Bo Gao, Hanrui Liu, Mengkai Zhu, Shun Zhang, Meiniang Wang, Yijun Ruan, Yue Zheng

“…Leukemia inhibitory factor (LIF) is a critical cytokine involved in various biological processes, including stem cell self-renewal, inflammation, and cancer progression. …”
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Association between B Cell Growth Factors and Primary Sjögren’s Syndrome-Related Autoantibodies in Patients with Non-Hodgkin’s Lymphoma by Zhenhua Xian, Dehua Fu, Shuang Liu, Yang Yao, Chun Gao

“…In current study, based on previous studies from animal model, new panels combining well-established cytokine (BAFF) and autoantibodies (anti-SSA/Ro) with newly identified cytokine (IL14) and autoantibodies (TSA) were used to evaluate the association between B cell growth factor and Sjögren’s related autoantibodies in NHL patients. …”
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Bioinformatics Analysis of miRNAs Targeting TRAF5 in DLBCL Involving in NF-κB Signaling Pathway and Affecting the Apoptosis and Signal Transduction by Chunyao Li, Lanshan Huang, Yongqin Wen, Muhua Yi, Min Gao

“…DEGs were significantly concentrated in the NF-κB signaling pathway and cytokine-cytokine receptor interaction, and involved in the process of immune response and protein binding. …”
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Influence of Body Mass Index on Inflammatory Profile at Admission in Critically Ill Septic Patients by Fernando G. Zampieri, Vanessa Jacob, Hermes V. Barbeiro, Fabiano Pinheiro da Silva, Heraldo P. de Souza

“…An array of thirty-two cytokines and chemokines was measured using Milliplex technology. …”
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Microglia-secreted TNF-α affects differentiation efficiency and viability of pluripotent stem cell-derived human dopaminergic precursors. by Shirley D Wenker, María Isabel Farias, Victoria Gradaschi, Corina Garcia, Juan Beauquis, María Celeste Leal, Carina Ferrari, Xianmin Zeng, Fernando J Pitossi

“…Those effects were ameliorated by inhibition of Tumour necrosis factor alpha, a cytokine which was previously detected in vivo and in conditioned media from activated BV-2 cells. …”
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Expression of the JAK/STAT Signaling Pathway in Bullous Pemphigoid and Dermatitis Herpetiformis by K. Juczynska, A. Wozniacka, E. Waszczykowska, M. Danilewicz, M. Wagrowska-Danilewicz, J. Wieczfinska, R. Pawliczak, A. Zebrowska

“…A family of eleven proteins comprises the Janus kinases (JAK) and signal transducers and activators of transcription (STAT) signaling pathway, which enables transduction of signal from cytokine receptor to the nucleus and activation of transcription of target genes. …”
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An artificial transcription factor that activates potent interferon-γ expression in human Jurkat T Cells by Ashley King, Davis Noblitt, Olivia Sherron, Olivia Sherron, Clara Kjerfve, Lydia Pless, Nicholas L. Truex

“…These studies demonstrate that transcriptional targeting of cytokine genes, rather than surface receptors, activates cytokine expression and shows significant potential for directing immune function.…”
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Panduratin A Inhibits TNF Alpha-Stimulated Endothelial Cell Activation Through Suppressing the NF-κB Pathway by Kriangkrai Kiatsoonthon, Nitchakarn Phimthong, Saranyapin Potikanond, Nitwara Wikan, Wutigri Nimlamool

“…We discovered that PA reduced the level of pro-inflammatory cytokine IL-6 and chemokine MCP-1 in the media collected from endothelial cells stimulated with TNF-α. …”
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Natural Cytotoxicity Receptors in Decidua Natural Killer Cells of Term Normal Pregnancy by Hideki Takahashi, Tatsuo Yamamoto, Motomi Yamazaki, Takayuki Murase, Takayuki Matsuno, Fumihisa Chishima

“…To investigate the changes in the maternal immune system at term pregnancy, we studied the expression of natural cytotoxicity receptors (NCRs) and the cytokine production of NK cells in term placenta decidua and peripheral blood. …”
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Identification of Differentially Expressed Genes in COVID-19 and Integrated Bioinformatics Analysis of Signaling Pathways by Linjie Fang, Tingyu Tang, Mengqi Hu

“…Downregulated DEGs were in cellular response to cytokine stimulus, IL-17 signaling pathway, FoxO signaling pathway, etc. …”
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Involvement of a 1-Cys peroxiredoxin in bacterial virulence. by Gilberto Hideo Kaihami, José Roberto Fogaça de Almeida, Suelen Silvana dos Santos, Luis Eduardo Soares Netto, Sandro Rogério de Almeida, Regina Lúcia Baldini

“…Infection of macrophages with the lsfA mutant strains resulted in higher levels of the cytokine TNF-α production due to the activation of the NF-kB and MAPK pathways, that are partially inhibited by the wild-type P. aeruginosa strain. …”
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Folic Acid Is Able to Polarize the Inflammatory Response in LPS Activated Microglia by Regulating Multiple Signaling Pathways by Antonia Cianciulli, Rosaria Salvatore, Chiara Porro, Teresa Trotta, Maria Antonietta Panaro

“…Inducible NO synthase (iNOS), nuclear transcription factor-kappa B (NF-κB) p65, MAPKs protein, and suppressors of cytokine signaling (SOCS)1 and SOCS3 were analyzed by western blotting. …”
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Altered Expressions of miR-1238-3p, miR-494, miR-6069, and miR-139-3p in the Formation of Chronic Brucellosis by Ferah Budak, Salih Haldun Bal, Gulcin Tezcan, Halis Akalın, Guher Goral, Haluk Barbaros Oral

“…The differentially expressed miRNAs and their predicted target genes involved in endocytosis, regulation of actin cytoskeleton, MAPK signaling pathway, and cytokine-cytokine receptor interaction and its chemokine signaling pathway indicate their potential roles in chronic brucellosis and its progression. …”
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Peran Kemokin dalam Patogenesis Rinitis Alergi by Effy Huriyati, Bestari J Budiman, Ricki Octiza

“…Purpose: To know the role of chemotactic cytokine (chemokine) in pathogenesis of allergic rhinitis. …”
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Central amygdala neuroimmune signaling in alcohol use disorder by Mariam Melkumyan, Patrick A. Randall, Yuval Silberman

“…Chronic alcohol consumption disrupts neuroimmune signaling, leading to altered cytokine expression and activation of glial cells, including astrocytes and microglia. …”
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Bioinformatics analysis identifies key secretory protein-encoding differentially expressed genes in adipose tissue of metabolic syndrome by Jiandong Zhou, Yunshan Guo, Xuan Liu, Weijie Yuan

“…KEGG pathway analysis of the SP-DEGs were involved in the TGF-beta signalling pathway, cytokine‒cytokine receptor interactions, the hippo signalling pathway, Malaria. …”
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ET-1 Promotes Differentiation of Periodontal Ligament Stem Cells into Osteoblasts through ETR, MAPK, and Wnt/β-Catenin Signaling Pathways under Inflammatory Microenvironment by Li Liang, Wei Zhou, Nan Yang, Jifeng Yu, Hongchen Liu

“…ET-1 is related to periodontitis and involved in the regulation of cytokines, but the mechanisms remain unclear. The aim of this study is to investigate how ET-1 affects proinflammatory cytokine expression and differentiation in human periodontal ligament stem cells (PDLSCs). …”
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Assessment of Ocriplasmin Effects on the Vitreoretinal Compartment in Porcine and Human Model Systems by Bart Jonckx, Michael Porcu, Aurelie Candi, Isabelle Etienne, Philippe Barbeaux, Jean H. M. Feyen

“…Retinal morphology was unaffected in all eyes. Cytokine profiles of ocriplasmin-treated eyes were not different from vehicle. …”
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OK-432 Acts as Adjuvant to Modulate T Helper 2 Inflammatory Responses in a Murine Model of Asthma by Cheng-Jang Wu, Pin-Hsun Tseng, Cheng-Chi Chan, Sara Quon, Li-Chen Chen, Ming-Ling Kuo

“…Prior vaccination with OK-432 formulated against OVA attenuated lung eosinophilic inflammation and Th2 cytokine responses that were caused by challenging with OVA through the airway. …”
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