Serum Levels of IL-1β, IL-6, TGF-β, and MMP-9 in Patients Undergoing Carotid Artery Stenting and Regulation of MMP-9 in a New In Vitro Model of THP-1 Cells Activated by Stenting by Rongrong Zhang, Fan Jiang, Cindy Si Chen, Tianzhu Wang, Jinzhou Feng, Tao Tao, Xinyue Qin

“…Monocyte is a significant source of inflammatory cytokines in vascular remodeling. Telmisartan could reduce inflammation. …”
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Interleukin 10 Plays an Important Role in Neonatal Rats with Hypoxic-Ischemia Associated with B-Cell Lymphoma 2 and Endoplasmic Reticulum Protein 29 by Xue Bai, Liu-Lin Xiong, Chang-Le Fang, Hao-Li Zhou, Lu-Lu Xue, Yue Hu, Qing-Jie Xia, Jia Liu, Jun-Yan Zhang, Ting-Hua Wang, Si-Jin Yang

“…Interleukin 10 (IL-10) is a synthetic inhibitor of human cytokines with immunomodulatory and anti-inflammatory effects. …”
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3-bromo-4-(2-hydroxyethyl)-7-methoxy-2H-chromen-2-one inhibits allergic reactions in IgE-mediated RBL-2H3 cells and a passive cutaneous anaphylaxis mouse model by Moonsu Kim, Huiji Kim, Sun Young Moon, Seong-Ah Shin, Minji Kim, Seyeon Choi, Sugeun Gwon, Jun Hyuck Lee, Hyun Ho Park, Chang Sup Lee

“…Additionally, 3-bromo-4-(2-hydroxyethyl)-7-methoxy-2H-chromen-2-one suppressed the production of allergy-related pro-inflammatory cytokines (IL-4, IL-13, and TNF-α) and inhibited key signaling pathways, including MAPK, AKT, and NF-κB. …”
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A new vaccination approach for Salmonellosis employing a multi-epitope vaccine based on live microbial cell factory from Lactococcus lactis by Reyhaneh Sadat Moosavi-Kohnehsari, Mahnaz Jafari-Sohi, Tohid Piri-Gharaghie, Shakiba Tolou-Shikhzadeh-Yazdi, Mona Aghassizadeh-Sherbaf, Romina Hosseinzadeh

“…Birds that received the L. lactis/pNZ8121-Multi epitope vaccination showed increased levels of interferon (IFN-γ) and NFkB1α, increased transcription rates of cytokines, and a significant presence of IgY antibodies specific to the multi epitope gene in their serum. …”
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Resistance to P. brasiliensis Experimental Infection of Inbred Mice Is Associated with an Efficient Neutrophil Mobilization and Activation by Mediators of Inflammation by Felipe Fornias Sperandio, Gisele Pesquero Fernandes, Ana Carolina Silvério Cerqueira Mendes, Giulia Maria de Alencar Castro Bani, Vera Lucia Garcia Calich, Eva Burger

“…Susceptible mice produced higher numbers of PMN; however, these cells were less effective in killing the fungi. Inflammatory cytokines were more pronounced in resistant mice, which supports their PCM raised resistance.…”
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Macrophage Activities in Myocardial Infarction and Heart Failure by Sophia Esi Duncan, Shan Gao, Michael Sarhene, Joel Wake Coffie, Deng Linhua, Xingru Bao, Zhang Jing, Sheng Li, Rui Guo, Jing Su, Guanwei Fan

“…Also, though inflammation is as a result of adverse HF in patients, but despite the fact that broad immunosuppression therapeutic target has been used in various clinical trials, no positive results have showed up, but rather, the focus on proinflammatory cytokines has proved more benefits in patients with HF. …”
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Essential Roles of PKA, iNOS, CD95/CD95L, and Terminal Caspases in Suppression of Eosinopoiesis by PGE2 and Other cAMP-Elevating Agents by Bianca de Luca, Pedro Xavier-Elsas, Mônica Barradas, Ricardo A. Luz, Túlio Queto, Carla Jones, Maria Augusta Arruda, Thiago Mattar Cunha, Fernando Queiroz Cunha, Maria Ignez Gaspar-Elsas

“…Overall, PGE2 and isoproterenol shared a requirement for four effector elements (iNOS, CD95L, CD95, and terminal caspases), which together define a pathway targeted by several soluble up- and downmodulators of eosinopoiesis, including drugs, mediators of inflammation, and cytokines.…”
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Telomere length sensitive regulation of interleukin receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signalling in the tumour microenvironment by Ananda Kishore Mukherjee, Subhajit Dutta, Ankita Singh, Shalu Sharma, Shuvra Shekhar Roy, Antara Sengupta, Megha Chatterjee, Soujanya Vinayagamurthy, Sulochana Bagri, Divya Khanna, Meenakshi Verma, Dristhi Soni, Anshul Budharaja, Sagar Kailasrao Bhisade, Vivek Anand, Ahmad Perwez, Nija George, Mohammed Faruq, Ishaan Gupta, Radhakrishnan Sabarinathan, Shantanu Chowdhury

“…This altered NF-kappa B signalling and affected downstream cytokines like IL6, IL8, and TNF. Further, IL1R1 expression was telomere-sensitive in triple-negative breast cancer (TNBC) clinical samples. …”
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Bioactive Compounds from Propolis on Bone Homeostasis: A Narrative Review by Vanessa Bertolucci, André Felipe Ninomiya, Giovanna Barbarini Longato, Luisa Oliveira Kaneko, Nilson Nonose, Pedro Paulo Menezes Scariot, Leonardo Henrique Dalcheco Messias

“…Key mechanisms include reducing inflammatory cytokines, protecting against oxidative stress, and upregulating growth factor essential for bone formation. …”
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Enhanced breast cancer cell targeting: RGD integrin ligand potentiates RWQWRWQWR’s cytotoxicity and inhibits migration by Andrea Barragán-Cárdenas, Daniel Castellar-Almonacid, Yerly Vargas-Casanova, Claudia Parra-Giraldo, Adriana Umaña-Pérez, Joel López-Meza, Zuly Rivera-Monroy, Javier García-Castañeda

“…Also, this peptide induces a reduction in migration and invasion associated with a diminish in metalloprotease 9 activity and a lesser release of IL-6, IL-10 and arginase cytokines. Conclusions: Our results suggest that this promising peptide can be considered for preclinical evaluation in the development of drugs to treat breast cancer and thus mitigate the impact of this disease.…”
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Pharmacological Effects of Antioxidant Mycosporine-Glycine in Alleviating Ultraviolet B-Induced Skin Photodamage: Insights from Metabolomic and Transcriptomic Analyses by Kai Wang, Ling Qin, Huan Lin, Mengke Yao, Junhan Cao, Qing Zhang, Changfeng Qu, Yingying He, Jinlai Miao, Ming Liu

“…Furthermore, M-Gly reduced inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and IL-1β, typically upregulated after UVB exposure. …”
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The Effect and Mechanism of TLR9/KLF4 in FFA-Induced Adipocyte Inflammation by Cuizhe Wang, Meixiu Zhang, Jinxiu Wu, Wei Li, Xiaodan Ha, Yajuan Gu, Bo Han, Jianxin Xie, Jun Zhang

“…ELISA was used to detect the release level of inflammatory cytokines. The triglyceride (TG) and glucose (GLU) testing cassettes were used to detect the TG and GLU levels in culture medium. …”
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Combination of potassium oxonate with anti-PD-1 for the treatment of colorectal cancer by Yuanyuan Wang, Chenxi Hu, Tianpeng Du, Jiawen Li, Kaiyuan Hui, Xiaodong Jiang

“…We also tested the changes of TME through flow cytometry of spleen of mice in each group, as well as the IHC of cytokines.ResultsThe co-therapy of PO and anti-PD-1 showed admirable anti-tumor effect compared with the control group and the single drug groups. …”
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Taenia crassiceps-Excreted/Secreted Products Induce a Defined MicroRNA Profile that Modulates Inflammatory Properties of Macrophages by Diana Martínez-Saucedo, Juan de Dios Ruíz-Rosado, César Terrazas, Blanca E. Callejas, Abhay R. Satoskar, Santiago Partida-Sánchez, Luis I. Terrazas

“…Here, we found that, while TcES reduced the production of inflammatory cytokines (IL-6, IL-12, and TNFα), they increased the release of IL-10 in LPS-induced bone marrow-derived macrophages (BMDM). …”
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Development and characterization of a chicory extract fermented by Akkermansia muciniphila: An in vitro study on its potential to modulate obesity-related inflammation by A. Chervet, R. Nehme, C. Defois-Fraysse, C. Decombat, C. Blavignac, C. Auxenfans, B. Evrard, S. Michel, E. Filaire, J.-Y. Berthon, A. Dreux-Zigha, L. Delort, F. Caldefie-Chézet

“…The anti-inflammatory and anti-obesity activities of C-Akm extract were studied by testing the extract (50 μg/mL) on the polarization of THP-1 into macrophages, the secretion of pro-inflammatory cytokines in LPS-stimulated PBMCs, and the secretion of leptin and adiponectin in adipospheroids derived from human adipose stem cells. …”
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Polymorphisms of Tumor Necrosis Factor-α, Transforming Growth Factor-β, and Interleukin-10 in Asthma Associated with Olive Pollen Sensitization by Blanca Cárdaba, David Calzada, Selene Baos, Miriam Aguerri, Joaquín Quiralte, Carlos Lahoz

“…Levels of serum-soluble cytokines were correlated with specific genotypes and clinical phenotypes. …”
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Multimodal low-opioid anesthesia as a factor in reducing the activation of the proinflammatory response in cardiac surgery by S.R. Maruniak, O.A. Loskutov, O.M. Druzhyna, I.R. Malysh, V.G. Kolesnikov, N.O. Korotchuk

“…The aim – to evaluate the effect of the low opioid anesthetic management scheme on the dynamics of cytokines (interleukin-6) during coronary artery bypass grafting (CABG). …”
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Branched-chain fatty acids from goat milk alleviate ulcerative colitis via the TLR4/NF-κB/NLRP3 pathway by Jiaxin Zhang, Jinjing Zhong, Zhengying Cui, Yu Shen, Yaping Zheng, Yu Zhang, Chaoxin Man, Yanmei Hou, Qianyu Zhao, Yujun Jiang

“…In conclusion, these results demonstrated that BCFAs in goat milk exerted effects on colitis-related inflammatory cytokines and inhibited inflammation by inducing the TLR4/NF-κB/NLRP3 pathway to alleviate DSS-induced ulcerative colitis. …”
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Phlorofucofuroeckol-A: A Natural Compound with Potential to Attenuate Inflammatory Diseases Caused by Airborne Fine Dust by Eun-Gyeong Lee, Sung-Kun Yim, Sang-Min Kang, Byung Jae Ahn, Chang-Kwon Kim, Mina Lee, Dongseob Tark, Gun-Hee Lee

“…Additionally, gene profiling revealed the early activation of various signature genes involved in the production of inflammatory cytokines and chemokines using gene profiling. Treatment with PFF-A markedly reduced the expression levels of pro-inflammatory and apoptosis-related genes and even elevated the Bmp gene families. …”
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T-bet+ILC3 in peripheral blood is increased in the ankylosing spondylitis with high disease activity by Yang Liu, Yi Shen, Hongbai Ding, Dongyi He, Peng Cheng, Xinyao Wu, Zheng Xiang, Lei Shen, Yanqin Bian, Qi Zhu

“…The levels of different ILC subsets and the expression of T-box transcription factor 21 (T-bet) and retinoic-acid-receptor-related orphan receptor gamma (RORγt) in peripheral blood were analyzed via flow cytometry. Additionally, 24 cytokines in plasma were measured using a Luminex liquid suspension chip. …”
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