Broadening horizons: molecular mechanisms and disease implications of endothelial-to-mesenchymal transition by Cheng Qian, Guanglu Dong, Chunmei Yang, Weiwei Zheng, Chongjin Zhong, Qiuhong Shen, Yin Lu, Yang Zhao

“…Numerous studies have proved that EndMT is a multifaceted biological event driven primarily by cytokines such as TGF-β, TNF-α, and IL-1β, alongside signaling pathways like WNT, Smad, MEK-ERK, and Notch. …”
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Role of Mitochondria-Associated Endoplasmic Reticulum Membrane in Inflammation-Mediated Metabolic Diseases by Themis Thoudam, Jae-Han Jeon, Chae-Myeong Ha, In-Kyu Lee

“…These mitochondrial DAMPs rapidly activate MAM-resident inflammasome components and other inflammatory factors, which promote inflammasome complex formation and release of proinflammatory cytokines in pathological conditions. Long-term stimulation of the inflammasome instigates chronic inflammation, leading to the pathogenesis of metabolic diseases. …”
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Blockade Effects of Anti-Interferon- (IFN-) γ Autoantibodies on IFN-γ-Regulated Antimicrobial Immunity by Dyah Ika Krisnawati, Yung-Ching Liu, Yuarn-Jang Lee, Yun-Ting Wang, Chia-Ling Chen, Po-Chun Tseng, Ting-Jing Shen, Chiou-Feng Lin

“…Treatment with patient serum significantly blocked the production of proinflammatory factors, including cytokines/chemokines and reactive oxygen/nitrogen species, by M1 macrophages. …”
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Pharmacological Therapy in the Heart as an Alternative to Cellular Therapy: A Place for the Brain Natriuretic Peptide? by Nathalie Rosenblatt-Velin, Suzanne Badoux, Lucas Liaudet

“…Indeed, differentiation and/or proliferation of cardiac precursor cells is controlled by various endogenous mediators, such as growth factors and cytokines, which could thus be used as pharmacological agents to promote regeneration. …”
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The curcumin-loaded zein-shellac nanoparticles using pH-driven method: Fabrication, characterization, and anti-inflammatory effect by Xinyi Lv, Zijian Wu, Limin Wang, Peibo Guo, Ao Qu, Wenjing Liang, Pengbo Zheng, Yuan Li, Wen Zhang

“…Notably, the levels of pro-inflammatory cytokines, namely tumor necrosis factor-α (TNF-α), mouse interleukin-6 (IL-6), and interleukin-1β (IL-1β), were significantly reduced. …”
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Immunomodulatory Properties of HLA-G in Infectious Diseases by Laurence Amiot, Nicolas Vu, Michel Samson

“…The polymorphism, the interference of viral proteins with HLA-G intracellular trafficking, and various cytokines have been described to modulate HLA-G expression during infections. …”
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Life stage impact on the human skin ecosystem: lipids and the microbial community by Martin P. Pagac, Bala Davient, Luca Antonio Plado, Hilbert Yuen In Lam, Shi Mun Lee, Aarthi Ravikrishnan, Wee Ling Esther Chua, Sneha Muralidharan, Aishwarya Sridharan, Antony S. Irudayaswamy, Ramasamy Srinivas, Stephen Wearne, Ahmad Nazri Mohamed Naim, Eliza Xin Pei Ho, H. Q. Amanda Ng, Junmei Samantha Kwah, Eileen Png, Anne K. Bendt, Markus R. Wenk, Federico Torta, Niranjan Nagarajan, John Common, Yap Seng Chong, Elizabeth Huiwen Tham, Lynette Pei-Chi Shek, Evelyn Xiu Ling Loo, John Chambers, Yik Weng Yew, Marie Loh, Thomas L. Dawson

“…Co-culturing Malassezia with keratinocytes demonstrated a link between 9,10-DiHOME and pro-inflammatory cytokines IL-1β and IL-6 production. We also observed strong correlations between other skin oxylipins and microbial taxa, highlighting life stage differences in sebum production and microbial community composition. …”
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Three anti-inflammatory polysaccharides from Lonicera japonica Thunb.: insights into the structure-function relationships by Yu Liu, Hongjing Dong, Dongxiao Sun-Waterhouse, Wenwen Li, Bin Zhang, Jinqian Yu, Zhichang Qiu, Zhenjia Zheng

“…They exhibited excellent protective effects (in a dose-dependent manner) in lipopolysaccharide-injured RAW264.7 macrophages and CuSO4-damaged zebrafish via reducing NO production and inhibiting the overexpressions of inflammation-related transcription factors, inflammatory proteins and cytokines in the NF-κB/MAPK signaling pathways. Their anti-inflammatory effects varied owing to their different molecular characteristics and chemical compositions. …”
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Activation of Macrophages by Oligomeric Proteins of Different Size and Origin by Indrė Dalgėdienė, Asta Lučiūnaitė, Aurelija Žvirblienė

“…After 48 h, expression of surface markers F4/80, CD68, CD86, and CD206 and secreted cytokines IL-10, IL-12, IL-23, and TNF-α was analysed. …”
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Antigen Presenting Cells and Stromal Cells Trigger Human Natural Killer Lymphocytes to Autoreactivity: Evidence for the Involvement of Natural Cytotoxicity Receptors (NCR) and NKG2... by Alessandro Poggi, Maria Raffaella Zocchi

“…Indeed, NK cells can kill and produce pro-inflammatory and regulating cytokines as IFN-γ, TNF-α and IL10 during interaction with autologous dendritic cells or bone marrow stromal cells or skin fibroblasts. …”
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Conditioned medium derived from mesenchymal stem cells and spinal cord injury: A review of the current therapeutic capacities by Gholam Reza Kaka, Farrokh Modarresi

“…CM encompasses neuroprotective growth factors and cytokines, such as stem cell factor (SCF), vascular endothelial growth factor (VEGF), and glial cell line-derived neurotrophic factor (GDNF). …”
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Airway Inflammation and the Pathogenesis of Asthma by Paul M O'Byrne

“…Also, these inflammatory cells can produce proinflammatory cytokines, such as granulocytc-macrophage colony-stimulating factor. interleukin (IL) 3 and IL-5, which may promote continuing inflammation in the airways. …”
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Matched serum- and urine-derived biomarkers of interstitial cystitis/bladder pain syndrome. by Tadeja Kuret, Igor Sterle, Rok Romih, Peter Veranič

“…A total of 33 different biomarkers were measured, including cytokines and chemokines, proteins involved in extracellular matrix remodeling, adhesion molecules, growth factors, and markers of oxidative stress using enzyme linked immunoassays and multiplex technology. …”
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Circulating proliferative factors versus portal inflow redistribution: mechanistic insights of ALPPS-derived rapid liver regeneration by Shiran Zhang, Yu Ma, Xue Chen, Shuai Wu, Geng Chen

“…The key words “liver regeneration/hypertrophy”, “portal vein ligation/embolization”, “two-stage hepatectomy”, “liver partition/split” and “future liver remnant” in combination with “mechanisms”, “hemodynamics”, “cytokines”, “growth factors” or “collaterals” were searched in the title and/or abstract. …”
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Salivary Biomarkers in Periodontitis Patients: A Pilot Study by Sarah Reddahi, Amal Bouziane, Sana Rida, Houssain Tligui, Oumkeltoum Ennibi

“…Periodontal examination and saliva sampling were performed in all patients. Levels of salivary cytokines including IL-1β, IL-6, MMP-8, and IL-10 were evaluated by a sandwich ELISA test kit. …”
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Comparative Neuroprotective Effects of Dexamethasone and Minocycline during Hepatic Encephalopathy by Maha Gamal, Zainab Abdel Wahab, Mohamed Eshra, Laila Rashed, Nivin Sharawy

“…Methods. 48 male albino rats were divided into 4 groups: control group, acute liver injury (ALI) group, minocycline pretreated ALI group, and dexamethasone pretreated ALI group. 24 hours after acute liver injury serum ammonia, liver enzymes, brain levels of heme oxygenase-1 gene, iNOS gene expression, nitrite/nitrate, and cytokines were measured. In addition, the grades of encephalopathy and brain water content were assessed. …”
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Mechanistic insight of curcumin: a potential pharmacological candidate for epilepsy by Saima Khatoon, Nida Kalam

“…In the present review, we reviewed curcumin’s modulatory effects on potential biomarkers involved in epileptogenesis including dendritic cells, T cell subsets, cytokines, chemokines, apoptosis mediators, antioxidant mechanisms, and cognition impairment. …”
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Role of Stat3 in Skin Carcinogenesis: Insights Gained from Relevant Mouse Models by Everardo Macias, Dharanija Rao, John DiGiovanni

“…Signal transducer and activator of transcription 3 (Stat3) is a cytoplasmic protein that is activated in response to cytokines and growth factors and acts as a transcription factor. …”
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Asthma in Sickle Cell Disease by Manisha Newaskar, Karen A. Hardy, Claudia R. Morris

“…While the pathophysiologic mechanism in atopic asthma involves up-regulation of Th2 cytokines, mast cell– and eosinophil-driven inflammation, plus increased activity of inducible nitric oxide synthase (iNOS) and arginase in airway epithelium resulting in obstructive changes and AHR, the exact mechanisms of AHR, obstructive and restrictive lung disease in SCD is unclear. …”
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Hypoglycaemic, anti-hyperlipidemic, and anti-inflammatory activities of Asparagus africanus (Asparaceae) extract on high-fat diet/streptozotocin-induced diabetes in Wistar rats by Focham Evans Ngwenah, Oumar Mahamat, Tume Christopher

“…Fasting blood glucose levels, inflammatory cytokines, and lipid profiles were assessed in diabetic rats. …”
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