Showing 21 - 40 results of 160 for search '"cytochrome P450"', query time: 0.09s Refine Results
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    RETRACTED ARTICLE: Association between cytochrome P450 1A1 (CYP1A1) gene polymorphisms and the risk of renal cell carcinoma: a meta-analysis by Fan-dong Meng, Ping Ma, Cheng-guang Sui, Xin Tian, You-hong Jiang

    Published 2015-01-01
    “…Abstract Cytochrome P450 1A1 (CYP1A1) usually metabolizes carcinogens to their inactive derivatives but occasionally converts the chemicals to more potent carcinogens. …”
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    In vitro study of size-dependent inhibition of human cytochrome P450 (P450) P450-1A2, P450-2A6, P450-2B6, P450-2C8, P450-2E1, P450-2J2, and P450-3A5 by zinc oxide nanoparticles (ZnONPs) by Lamia Chowdhury, Yuh Fen Pung, Swee Yong Pung, Chin Eng Ong, Cin Kong, Yan Pan

    Published 2025-02-01
    “…However, these ZnONPs may potentially inhibit enzyme activities. Cytochrome P450 (P450-) isozymes, which play a crucial function in human bio-transforming drugs, can be inhibited by ZnONPs, leading to slower clearance of co-administrated drugs and elevated drug plasma concentrations. …”
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  19. 39

    Metabolic Characteristics of Oxcarbazepine (®Trileptal) and their Beneficial Implications for Enzyme Induction and Drug Interactions by Johann W. Faigle, Guenter P. Menge

    Published 1990-01-01
    “…Hepatic oxygenases of the cytochrome P-450 family play a major role in the clearance of various anti-epileptic drugs. …”
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    High on Cannabis and Calcineurin Inhibitors: A Word of Warning in an Era of Legalized Marijuana by Naomi Hauser, Tanmay Sahai, Rocco Richards, Todd Roberts

    Published 2016-01-01
    “…Tacrolimus has a narrow therapeutic index with variable oral bioavailability and metabolism via cytochrome P-450 3A enzyme. Toxicity can occur from overdosing or from drug-drug interactions with the simultaneous administration of cytochrome P-450 3A inhibitors and possibly P-glycoprotein inhibitors. …”
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