Hepatitis C Virus Infection and Mixed Cryoglobulinemia by Gianfranco Lauletta, Sabino Russi, Vincenza Conteduca, Loredana Sansonno

“…Hepatitis C virus (HCV) chronic infection is recognized as the major cause of mixed cryoglobulinemia (MC). Its persistence represents a continuous stimulus for host immune system with production of circulating immune complexes (ICs), one-third of them with cryoprecipitate property. …”
Get full text

Hepatitis C Virus, Cryoglobulinemia, and Kidney: Novel Evidence by Fabrizio Fabrizi

“…The most frequent HCV-associated nephropathy is type I membranoproliferative glomerulonephritis, usually in the context of type II mixed cryoglobulinemia. Various approaches have been tried for the treatment of HCV-related glomerulonephritis, including immunosuppressive therapy (corticosteroids and cytotoxic agents), plasma exchange and antiviral agents. …”
Get full text

Concomitant Nephrotic Syndrome and Cryoglobulinemia in a Case of Malignant Mesothelioma by Kei Nagai, Hiroaki Tachi, Kohei Inoue, Atsushi Ueda

“…Malignant pleural mesothelioma is rarely associated with nephrotic syndrome. Cryoglobulinemia is found in various pathological statuses, such as hepatitis C virus infection but rarely in malignant neoplasms. …”
Get full text

Symptomatic Mixed Cryoglobulinemia during HIV Primary Infection: A Case Report by Philippe Genet, Laurence Courdavault, Bouchra Wifaq, Juliette Gerbe

“…Cryoglobulinemia progressively disappeared in several months after HAART.…”
Get full text

Cryoglobulinemia Associated With Multiple Myeloma in a Dog Presenting With Epistaxis and Skin Lesions by Myrto Spyropoulou, Ivan Montanes‐Sancho, Adam G. Gow, Suzanne Bussey

“…A diagnosis of multiple myeloma associated with cryoglobulinemia was made. The patient received palliative care with prednisolone while the owner was considering chemotherapy. …”
Get full text

B-cell non-Hodgkin's lymphoma in the patient with chronic hepatitis C and mixed cryoglobulinemia by V. S. Adonyeva, Ye. A. Kolodyazhnaya, A. B. Bochkarev

“…Presence of mixed cryoglobulinemia within symptomatics of chronic HCV-infection, long history of infection were indicative of HCV-associated lymphoma development. …”
Get full text

Type III Mixed Cryoglobulinemia and Antiphospholipid Syndrome in a Patient With Partial DiGeorge Syndrome by Alice D. Chang, Raffi Tachdjian, Kerry Gallagher, Deborah K. McCurdy, Charles Lassman, E. Richard Stiehm, Ora Yadin

“…This is the first report of a patient with partial DGS presenting with APS and type III mixed cryoglobulinemia possibly due to Streptococcal infection.…”
Get full text

Clinical role of endothelial dysfunction and hemostasis gene allelic variants in hepatitis C virus-associated cryoglobulinemia by M. V. Sokolova, Ye. Ye. Starostina, T. N. Krasnova, L. M. Samokhodskaya, T. P. Rozina, V. G. Avdeyev, M. G. Artemova, Ye. B. Yarovaya, N. A. Mukhin

“…Original study included overall 72 patients with CHC and cryoglobulinemia: 21 patients had CryoVas, 51 - CHC without vasculitis. …”
Get full text

A Rare Cause of Unilateral Central Retinal Vein Occlusion in a Young Patient: Type III Mixed Cryoglobulinemia by Sibel Doguizi, Mehmet Ali Sekeroglu, Mustafa Alpaslan Anayol, Pelin Yilmazbas

“…Based on the clinical, laboratory, and ophthalmological assessments, we diagnosed this case as type III mixed cryoglobulinemia with unilateral CRVO with macular edema. …”
Get full text

A Rare Case of Eosinophilic Granulomatosis with Polyangiitis Associated with Cryoglobulinemia Presenting with a Bullous Skin Eruption of the Lower Limbs by D. D. K. Abeyaratne, C. Liyanapathirana, C. L. Fonseka, P. W. M. C. S. B. Wijekoon

“…We report a rare case of EGPA overlapped with mixed essential cryoglobulinemia presenting with a bullous skin eruption. …”
Get full text

HCV Proteins and Immunoglobulin Variable Gene (IgV) Subfamilies in HCV-Induced Type II Mixed Cryoglobulinemia: A Concurrent Pathogenetic Role by Giuseppe Sautto, Nicasio Mancini, Laura Solforosi, Roberta A. Diotti, Massimo Clementi, Roberto Burioni

“…The association between hepatitis C virus (HCV) infection and type II mixed cryoglobulinemia (MCII) is well established, but the role played by distinct HCV proteins and by specific components of the anti-HCV humoral immune response remains to be clearly defined. …”
Get full text

Inicio del síndrome de Sjögren con manifestaciones extraglandulares: reporte de caso by Tania Liliana Molina-Huertas, Sara Carolina Navarro-Salgado

Subjects: Get full text

Combined Treatment with Antiviral Therapy and Rituximab in Patients with Mixed Cryoglobulinemia: Review of the Literature and Report of a Case Using Direct Antiviral Agents-Based Antihepatitis C Virus Therapy by Teresa Urraro, Laura Gragnani, Alessia Piluso, Alessio Fabbrizzi, Monica Monti, Elisa Fognani, Barbara Boldrini, Jessica Ranieri, Anna Linda Zignego

“…Mixed cryoglobulinemia (MC) is an autoimmune/B-cell lymphoproliferative disorder associated with Hepatitis C Virus (HCV) infection, manifesting as a systemic vasculitis. …”
Get full text

Nursing management for 5 patients undergoing Rituximab treatment for cryoglobulinemia-associated membranoproliferative glomerulonephritis (利妥昔单抗治疗5例冷球蛋白血症相关膜增生性肾小球肾炎患者的护理) by LI Aijuan (李爱娟)

Subjects: Get full text

WALDENSTRÖM MACROGLOBULINEMIA - A STATE-OF-THE-ART REVIEW: PART 1: EPIDEMIOLOGY, PATHOGENESIS, CLINICOPATHOLOGIC CHARACTERISTICS, DIFFERENTIAL DIAGNOSIS, RISK STRATIFICATION, AND C... by Michele Bibas, Shayna Sarosiek, Jorge J. Castillo

Subjects: “…Amyloidosis, Anemia, B cells, BCL2, Bruton tyrosine kinase, Bing-Neel syndrome, Bruton Tyrosine Kinase Inhibitors, Cryoglobulinemia, CXCR4, flow cytometry, hyperviscosity, lymphoplasmacytic lymphoma, MYD88, Waldenström Macroglobulinemia, Peripheral neuropathy.…”
Get full text

A Nonseminomatous Germ Cell Tumor Presenting as a Mixed Cryoglobulinemic Vasculitis by Gabriel Cojuc-Konigsberg, Isabel Natera-Comte, Blanca E. López Graciano, Luis Gerardo Mosqueda López, José Alonso Ávila-Rojo, Braulio Martínez, Juan C. Ramírez-Sandoval

“…Background. Mixed cryoglobulinemia syndrome (MCS) is a rare entity with a variety of causes but has not been associated with testicular germ cell tumors. …”
Get full text

Autoimmune and Neoplastic Thyroid Diseases Associated with Hepatitis C Chronic Infection by Poupak Fallahi, Silvia Martina Ferrari, Ugo Politti, Dilia Giuggioli, Clodoveo Ferri, Alessandro Antonelli

“…In patients with “HCV-associated mixed cryoglobulinemia” (MC + HCV), a higher prevalence of thyroid autoimmune disorders was shown not only compared to controls, but also versus HCV patients without cryoglobulinemia. …”
Get full text

Virus-induced Systemic Vasculitides: New Therapeutic Approaches by Loïc Guillevin

“…In vasculitis related to HCV-associated cryoglobulinemia, plasma exchanges improve the outcome but the poor effectiveness of antiviral drugs is not able to favor, usually, a definite recovery of the patients and relapses are frequent.…”
Get full text

The clinical role of blood coagulation and platelet receptors gene allelic variants in development of cryoglobulinemic vasculitis at chronic hepatitis C by Yekaterina Ye. Starostina, M. V. Sokolova, L. M. Samokhodskaya, T. П. Rozina, T. N. Krasnova, Ye. B. Yarovaya, N. A. Mukhin

“…Original study included overall 200 patients with CHCs and liver cirrhosis in its outcome, who were divided into 3 groups: patients without cryoglobulinemia (CG, n=123), those with asymptomatic cryoglobulinemia (ACG, n=40) and with cryoglobulinemic vasculitis (CGV, n=37). …”
Get full text

Long-term results of antiviral therapy in patients with chronic hepatitis C with sustained virologic response by T. M. Ignatova, T. N. Lopatkina, V. P. Chulanov, Ye. V. Gaydasheva, S. N. Batskikh, G. V. Mikhaylovskaya, D. T. Abdurakhmanov, S. Yu. Karpov, Ye. N. Nikulkina, O. A. Chernova

“…No data on latent HCVinfection was obtained not in a single case, including patients with relapse of cryoglobulinemia syndrome. A principal cause of elevation of alanine transaminase activity was non-alcoholic steatohepatitis. …”
Get full text