Simulation of Image-Guided Microwave Ablation Therapy Using a Digital Twin Computational Model by Frankangel Servin, Jarrod A. Collins, Jon S. Heiselman, Katherine C. Frederick-Dyer, Virginia B. Planz, Sunil K. Geevarghese, Daniel B. Brown, William R. Jarnagin, Michael I. Miga

“…Emerging computational tools such as healthcare digital twin modeling are enabling the creation of patient-specific surgical planning, including microwave ablation to treat primary and secondary liver cancers. …”
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Evidence in Practice of Tissue Healing with Latex Biomembrane: Integrative Review by Suélia de Siqueira Rodrigues Fleury Rosa, Mário Fabrício Fleury Rosa, Marcos Augusto Moutinho Fonseca, Glécia Virgolino da Silva Luz, Carlos Federico Domínguez Avila, Aldira Guimarães Duarte Domínguez, Aldene Guimarães Duarte Dantas, Von Braun Richter

“…The LBM was characterized as a good therapeutic alternative in cases of wounds, including chronic diseases, such as diabetes mellitus and PU, due to its relevant potential for wound healing stimulation, acceleration of cell tissue mending and revascularization, or the reestablishment of angiogenic functions (creation of new blood vessels). The LBM was also confirmed to be safe as a biocompatible material whose structural qualities (elasticity, adaptability, impermeability, and possibility of suture), devoid of toxicity, allowed interaction between tissues and presented no hypersensitivity inducer and no antimicrobial effect.…”
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In silico design of an epitope-based vaccine ensemble for fasliolopsiasis by Ruchishree Konhar, Ruchishree Konhar, Kanhu Charan Das, Kanhu Charan Das, Aiboklang Nongrum, Rohan Raj Samal, Shailesh Kumar Sarangi, Devendra Kumar Biswal, Devendra Kumar Biswal

“…The increasing prevalence of medication resistance and the necessity for an effective vaccination make controlling these diseases challenging.MethodsOver the last decade, we have achieved major advances in our understanding of intestinal fluke biology by in-depth interrogation and analysis of evolving F. buski omics datasets. The creation of large omics datasets for F. buski by our group has accelerated the discovery of key molecules involved in intestinal fluke biology, toxicity, and virulence that can be targeted for vaccine development. …”
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Serological insights from SARS-CoV-2 heterologous prime and boost responses in Thailand by Daniel Ward, Lapasrada Pattarapreeyakul, Rujiraporn Pitaksalee, Naphatcha Thawong, Waritta Sawaengdee, Suthida Tuntigumthon, Catriona Patterson, Kevin Tetteh, Susana Campino, Panadda Dhepakson, Surakameth Mahasirimongkol, Taane G. Clark

“…Overall, our study underscores the necessity for vaccine (re-)development and the creation of serological tools to monitor vaccine performance.…”
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Exploring machine learning algorithms for predicting fertility preferences among reproductive age women in Nigeria by Zinabu Bekele Tadese, Teshome Demis Nimani, Kusse Urmale Mare, Fetlework Gubena, Ismail Garba Wali, Jamilu Sani

“…BackgroundFertility preferences refer to the number of children an individual would like to have, regardless of any obstacles that may stand in the way of fulfilling their aspirations. Despite the creation and application of numerous interventions, the overall fertility rate in West African nations, particularly Nigeria, is still high at 5.3% according to 2018 Nigeria Demographic and Health Survey data. …”
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A Simple Machine Learning-Based Quantitative Structure–Activity Relationship Model for Predicting pIC₅₀ Inhibition Values of FLT3 Tyrosine Kinase by Jackson J. Alcázar, Ignacio Sánchez, Cristian Merino, Bruno Monasterio, Gaspar Sajuria, Diego Miranda, Felipe Díaz, Paola R. Campodónico

“…<b>Conclusions:</b> These results represent a significant advancement in the field of FLT3 inhibitor discovery, offering a reliable, practical, and efficient approach for early-stage drug development, potentially accelerating the creation of targeted therapies for AML.…”
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The Importance of Coordinated Actions in Preventing the Spread of Yellow Fever to Human Populations: The Experience from the 2016-2017 Yellow Fever Outbreak in the Northeastern Reg... by Márcio Junio Lima Siconelli, Danillo Lucas Alves Espósito, Nathália Cristina Moraes, Julia Maria Ribeiro, Lívia Perles, Maria Angélica Dias, Adolorata Aparecida Bianco Carvalho, Karin Werther, Natália Coelho Couto de Azevedo Fernandes, Silvia D'Andretta Iglezias, Karina Paes Bürger, Benedito Antonio Lopes da Fonseca

“…Public health actions included dissemination of information on YF transmission, investigation of the probable location of NHP infection, characterization of the environment, and subsequent creation of the blueprint from which prevention and control measures were implemented. …”
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Pastoral livestock farming constraints and adaptation strategies in response to institutional reforms in the Sudano-Sahelian zone of West Africa by Basnewindé Ilboudo, Alhassane Zaré, Alhassane Zaré, Innocent Charles Emmanuel Traoré, Innocent Charles Emmanuel Traoré, Loyapin Bondé, Reginald Tang Guuroh, Reginald Tang Guuroh, Reginald Tang Guuroh, Oumarou Ouédraogo

“…In Burkina Faso, the pastoral zone creation process began in 1980 to sedentarize livestock farmers, reduce social conflict, and strengthen livestock production. …”
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In-House Fabrication and Validation of 3D-Printed Custom-Made Medical Devices for Planning and Simulation of Peripheral Endovascular Therapies by Arianna Mersanne, Ruben Foresti, Chiara Martini, Cristina Caffarra Malvezzi, Giulia Rossi, Anna Fornasari, Massimo De Filippo, Antonio Freyrie, Paolo Perini

“…CTA images were analyzed using Syngo.via by a specialist to formulate a medical prescription that guided the model’s creation. The CTA data were then processed in OsiriX MD to generate the .STL file, which is further refined in a Meshmixer. …”
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Development of the cultural tailoring score (CTS): a scoring instrument to assess cultural tailoring of health messaging by Claudia Parvanta, Kayleigh Murray, Samantha Boddupalli, Natalie Erasme, Rheese McNab, Vijay Prajapati, Arabel Severe, Aura Reyes, Richard Harner, Rhonda Holliday

“…While contractors and partner organizations are asked to produce culturally appropriate materials, there are no government-endorsed metrics to assess the “cultural content” of health communication materials.Aims To fill this implementation gap we created a cultural tailoring score that can be used to guide creation or pretesting of health communication materials. …”
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Comparative effectiveness of buprenorphine-naloxone versus methadone for treatment of opioid use disorder: a population-based observational study protocol in British Columbia, Cana... by Lawrence C McCandless, Malcolm Maclure, M Eugenia Socías, Evan Wood, Paul Gustafson, Robert W Platt, Bohdan Nosyk, Sander Greenland, Micah Piske, Trevor Thomson, Emanuel Krebs, Natt Hongdilokkul, Julie Bruneau, M Ehsan Karim, Judith I Tsui

“…Sensitivity analyses will be used to assess the robustness of results to heterogeneity in the patient population and threats to internal validity.Ethics and dissemination The protocol, cohort creation and analysis plan have been approved and classified as a quality improvement initiative exempt from ethical review (Providence Health Care Research Institute and the Simon Fraser University Office of Research Ethics). …”
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Construction of an anaplastic thyroid cancer stratification signature to guide immune therapy selection and validation of the pivotal gene HLF through in vitro experiments by Li Pengping, Yin Kexin, Xie Yuwei, Sun Ke, Li Rongguo, Wang Zhenyu, Jin Haigang, Wang Shaowen, Huang Yuqing

“…Through weighted gene co-expression network analysis (WGCNA), we identified 12 differentially expressed genes closely associated with immunotherapy outcomes. This led to the creation of a refined signature for predicting ATC’s immune responsiveness to anti-PD1 therapy, which was further validated using thyroid cancer cohorts from TCGA and nine melanoma cohorts from clinical trials. …”
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Identification of antibiotic use patterns in poultry farms in the southwest region of Bangladesh by Sarder Safiqul Islam, Ratna Ghosh, Md. Shafiqul Islam, Minhazul Abedin Sun, Mustajabur Rahman, Dhiman Mondol

“…It can be concluded that most of the chicken farmers are using antibiotics indiscriminately which suggests proper education and awareness creation of poultry farmers to reduce the risks associated with antibiotic use.…”
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The linkage between economic literacy and students’ intention of starting business: The mediating role of entrepreneurial alertness by Agus Wibowo, Bagus Shandy Narmaditya, Ratieh Widhiastuti, Ari Saptono

“…IMPLICATIONS: The result of this research can provide insight into the literature on the entrepreneurship theme and policymakers concerned with delivering new business creation. Besides, educational institutions can consider the matter of economic literacy to be part of their curricula in order to foster the students’ intention of starting a business. …”
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An integrated approach to flood risk assessment using multi-criteria decision analysis and geographic information system. A case study from a flood-prone region of Pakistan by Muhammad Ibrahim, Aidi Huo, Aidi Huo, Aidi Huo, Waheed Ullah, Safi Ullah, Zhao Xuantao

“…This combination of methods enabled the creation of accurate, data-driven flood risk maps. …”
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Study for Improving Maternal Pregnancy And Child ouTcomes (IMPACT): a study protocol for a Swedish prospective multicentre cohort study by Anders Larsson, Henrik Imberg, Marius Kublickas, Anna-Karin Wikström, Peter Lindgren, Lina Bergman, Bo Jacobsson, Anna Sandström, Stefan Hansson, Peter Conner, Ylva Carlsson

“…Inclusion in the study began in November 2018 with a targeted sample size of 45 000 pregnancies by end of 2021. Creation of a new risk prediction model will then be developed, validated and implemented. …”
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A qualitative systematic review of umbilical cord care practices in Nigeria by Precious Ebube Anyakorah, Florence Chinelo Aguna, David Chinaecherem Innocent, Anthony Chinonso Uwandu-Uzoma, Uzochukwu Godswill Ekeleme, Chidera Chisom Obasi, Stanley Chinedu Eneh, Chidinma Peace Ahunam, Ihuoma Chimdimma Dike, Vivian Chidimma Maduekwe, Oluwaseunayo Deborah Ayando, Chinazaekpere Oguguo Duruji, Rejoicing Chijindum Innocent, Princess Chidiebube Uwaezuoke, Oluwafunmilayo Opeyemi Adenuga, Chiagoziem Ogazirilem Emerole

“…Despite its limitations, the study is an important resource for guiding future research, policy creation, and interventions to improve maternal and newborn health outcomes in Nigeria.…”
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Automatic Segmentation of Asphalt Cracks on Highways After Large-Scale and Severe Earthquakes Using Deep Learning-Based Approaches by Mehmet Yilmaz, Erkut Yalcin, Fatih Demir, Ahmet Munir Ozdemir, Muhammed Atar, Aysegul Gunes, Beyza Furtana Yalcin, Ertugrul Cambay

“…The innovative aspect of this research lies in the creation of a unique post-earthquake dataset, collected and labeled from highways affected by the February 6, 2023 earthquakes in Turkey (Mw = 7.7 and Mw = 7.6). …”
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STANDARDIZATION OF CLINICAL PHARMACIST FUNCTIONAL RESPONSIBILITIES IN HOSPITAL SETTING IN UKRAINE AND ABROAD by Andriy Zimenkovsky, Х.І. Макух, Myroslava Sekh, Marta Zayats

“…Further integration of the clinical pharmacist into national health care, as an equal and integral member of a multidisciplinary team of specialists, is possible under the conditions of the creation of relevant legislative\regulatory acts and the development or optimization of national clinical pharmaceutical education at all levels.…”
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Constitutional consolidation of the rule of law as the basis for the development of the Ukrainian state: historical origins and implementation practice by Lutskyi R., Kaleniuk O., Lytsur M.

“…As a result of the research conducted, it was found that this principle, which forms the basis of the constitutional order, is proclaimed and operates in our country. The creation by the state of reliable and favorable conditions for the implementation of the rule of law in all social relations, the consolidation at the legislative level of guarantees for its enforcement and the mechanism of legal protection in case of violation of this principle are its priorities, because in a state governed by the rule of law, a person, his or her life, health, honor, dignity, rights and security are the highest value. …”
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