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  1. 1421

    Climate Impact on Evapotranspiration in the Yellow River Basin: Interpretable Forecasting with Advanced Time Series Models and Explainable AI by Sheheryar Khan, Huiliang Wang, Umer Nauman, Rabia Dars, Muhammad Waseem Boota, Zening Wu

    Published 2025-01-01
    “…Advanced data preprocessing techniques, including Yeo-Johnson and Box-Cox transformations, Savitzky–Golay smoothing, and outlier elimination, were applied to improve data quality. …”
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  2. 1422

    Fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) and mortality among survivors of liver cirrhosis: a prospective cohort study by Danial Fotros, Azita Hekmatdoost, Fereshteh Pashayee-khamene, Sara Karimi, Saleheh Ahmadzadeh, Mehdi Saberifiroozi, Behzad Hatami, Zahra Yari

    Published 2025-01-01
    “…The study classified participants into three groups based on their FODMAPs consumption and assessed the risk of mortality using Cox proportional hazards regression models. Results Total FODMAPs intake was associated with increased overall mortality risk (T3 vs. …”
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  3. 1423

    CK19 protein expression: the best cutoff value on the prognosis and the prognosis model of hepatocellular carcinoma by Chenglei Yang, Wanyan Xiang, Zongze Wu, Nannan Li, Guoliang Xie, Juntao Huang, Lixia Zeng, Hongping Yu, Bangde Xiang

    Published 2025-01-01
    “…The predictors were screened using univariate and multivariate COX regression and least absolute shrinkage and selection operator (LASSO) regression to construct nomogram prediction models, and their predictive potentials were assessed using calibration curves and AUC values. …”
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  4. 1424

    Association of geriatric nutritional risk index with renal prognosis and all-cause mortality among older patients with chronic kidney disease: a secondary analysis of CKD-ROUTE stu... by Lei Chen, Mengyao Yan, Jie Li, Xue Zhao, Lu Zeng, Zhumei Gao, Hongli Jiang, Limin Wei

    Published 2025-12-01
    “…Associations between GNRI and clinical outcomes were estimated using Cox proportional hazards model analysis. Multivariable linear mixed regression models with random intercepts were used to assess the association between GNRI and estimated glomerular filtration rate (eGFR) decline per year.Results During the median follow-up period of 2.92 years, there were 123 (22.86%) CKD progression events, 44 (8.18%) deaths, and 76 (14.13%) cardiovascular events. …”
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  5. 1425

    Desmoglein-2 was a novel cancer-associated fibroblasts-related biomarker for oral squamous cell carcinoma by Jin Liu, Zhonghao Sun, Shihui Cao, Hao Dai, Ze Zhang, Jingtao Luo, Xudong Wang

    Published 2025-01-01
    “…Differentially expressed genes and Cox regression analyses were used to identify candidate genes, and their functions were evaluated using Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses. …”
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  6. 1426

    Predictive nomograms of repeat intrahepatic recurrence and overall survival after radiofrequency ablation of recurrent colorectal liver metastases by Ji-Chen Wang, Bin-Bin Jiang, Zhong-Yi Zhang, Yu-Hui Liu, Li-Jin Shao, Song Wang, Wei Yang, Wei Wu, Kun Yan

    Published 2024-12-01
    “…Potential prognostic factors associated with rIHR and OS, after RFA, were identified by using the competing-risks and Cox proportional hazard models, respectively, and were used to construct the nomogram. …”
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  7. 1427

    New rectum dose surface mapping methodology to identify rectal subregions associated with toxicities following prostate cancer radiotherapy by Artemis Bouzaki, Dylan Green, Marcel van Herk, Jane Shortall, Tanuj Puri, Sarah Kerns, David Azria, Marrie-Pierre Farcy-Jacquet, Jenny Chang-Claude, Ananya Choudhury, Alison Dunning, Maarten Lambrecht, Barbara Avuzzi, Dirk De Ruysscher, Petra Seibold, Elena Sperk, Christopher Talbot, Ana Vega, Liv Veldeman, Adam Webb, Barry Rosenstein, Catharine M. West, Eliana Gioscio, Tiziana Rancati, Eliana Vasquez Osorio, Alan McWilliam

    Published 2025-01-01
    “…Voxel-based analysis of the dose surface maps for the manual and automatic contours against individual rectal toxicities was performed using Student’s t permutation test and Cox Proportional Hazards Model (CPHM). Significance was defined by permutation testing. …”
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  8. 1428
  9. 1429

    Nonlinear association between proteinuria levels and the risk of cardiovascular disease events and all-cause mortality among chronic kidney disease patients by Haiying Song, Yuheng Liao, Haofei Hu, Qijun Wan

    Published 2024-12-01
    “…The primary outcome of this study was the composite of cardiovascular events or all-cause death. Cox proportional hazards regression, smooth curve fitting, piecewise linear regression, and subgroup analyses were used.Results The mean age of the included individuals was 67.3 ± 13.6 years old. …”
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  10. 1430

    Modeling extracellular matrix through histo-molecular gradient in NSCLC for clinical decisions by Camila Machado Baldavira, Tabatha Gutierrez Prieto, Juliana Machado-Rugolo, Juliana Machado-Rugolo, Jurandir Tomaz de Miranda, Lizandre Keren Ramos da Silveira, Ana Paula Pereira Velosa, Walcy Rosolia Teodoro, Alexandre Ab’Saber, Teresa Takagaki, Vera Luiza Capelozzi

    Published 2022-11-01
    “…In our cohort, WNT3A, WNT5A, heparan sulfate and SPARC played an important role in the Cox regression model, influencing the overall survival (OS) of patients, be it directly or indirectly, with the SPARC expression stratifying the OS into two groups: 97 months for high expression; and 65 for low expression. …”
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  11. 1431

    Novel machine learning algorithm in risk prediction model for pan-cancer risk: application in a large prospective cohort by Chi-Pang Wen, Xifeng Wu, Qingfeng Hu, Huakang Tu, Shan Pou Tsai, David Ta-Wei Chu

    Published 2024-07-01
    “…Objective To develop and validate machine-learning models that predict the risk of pan-cancer incidence using demographic, questionnaire and routine health check-up data in a large Asian population.Methods and analysis This study is a prospective cohort study including 433 549 participants from the prospective MJ cohort including a male cohort (n=208 599) and a female cohort (n=224 950).Results During an 8-year median follow-up, 5143 cancers occurred in males and 4764 in females. Compared with Lasso-Cox and Random Survival Forests, XGBoost showed superior performance for both cohorts. …”
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  12. 1432

    Effect of visit-to-visit blood pressure variability on cardiovascular events in populations with different body mass indexes: a prospective cohort study by Shouling Wu, Haojia Chen, Youren Chen, Weiqiang Wu, Jianhuan Huang, Zekai Chen, Zhichao Chen, Xiuzhu Yan

    Published 2020-09-01
    “…We further divided these groups into four subgroups based on the ARVSBP. A Cox regression model was used to calculate the HRs of the ARVSBP on CVEs in the same and different BMI groups. …”
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  13. 1433

    The association of sexual frequency with cardiovascular diseases incidence and all-cause mortality by Tian-Qi Teng, Jing Liu, Meng-Meng Wang, De-Gang Mo, Rui Chen, Jia-Chao Xu, Zi-Han Dong, Ning Zhang, Hai-Chu Yu

    Published 2024-12-01
    “…We analyzed 17,243 participants from the National Health and Nutrition Examination Survey(NHANES)(2005–2016), comparing CVD incidence and all-cause mortality risks across sexual frequencies using multivariable Logistic and Cox regression models. Kaplan-Meier curves assessed survival probability stratified by sexual frequency, and a restricted cubic spline regression examined the nonlinear relationship between sexual frequency, CVD and survival status. …”
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  14. 1434

    Comparison of Oncological Outcomes After Curative Resection for Right-side Colon Cancer and Left-side Colon Cancer: a Retrospective Observational Study by Mehmet Torun, Orhan Uzun, Mustafa Duman, Erdal Polat, Aziz Serkan Senger, Mürşit Dinçer, Ömer Özduman, Selçuk Gülmez, Ahmet Orhan Sunar

    Published 2024-12-01
    “…Statistical analyses were performed using the chi-squared test, Fisher’s exact test, Mann-Whitney U test, the Kaplan-Meier method, and Cox regression analysis. Results: Among the 182 patients, 108 (59.3%) had RCC, and 74 (40.7%) had LCC. …”
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  15. 1435

    Association between cytokines and progression-free survival in ovarian cancer following CRS/HIPEC treatment by Chao-Yu Chen, Ting-Yao Wang, Jing-Lan Liu, Yu-Che Ou, Li-Wen Lee, Chien-Hui Hung, Chuan-Pin Lee, Jrhau Lung

    Published 2025-01-01
    “…Methods From January 2018 to January 2023, serum cytokine levels were analyzed in 34 EOC patients (17 primary, 17 recurrent) before and after CRS/HIPEC using MILLIPLEX Magnetic Bead Panels. Cox proportional hazards regression calculated adjusted hazard ratios (HRs) after controlling for clinical variables. …”
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  16. 1436

    Lymphopenia Is Associated with Gross Target Volumes and Fractions in Hepatocellular Carcinoma Patients Treated with External Beam Radiation Therapy and Also Indicates Worse Overall... by Hai-Ge Zhang, Ping Yang, Tao Jiang, Jian-Ying Zhang, Xue-Juan Jin, Yong Hu, Jing Sun, Shi-Suo Du, Zhao-Chong Zeng

    Published 2019-01-01
    “…Kaplan–Meier analysis, log-rank test, as well as univariate and multivariate Cox regression were performed to assess the relationship between lymphocyte nadir and overall survival (OS). …”
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  17. 1437

    Prognostic significance of CDK1 expression in diffuse large B-Cell lymphoma by Qiuni Chen, Lei Xu, Chuanyang Lu, Yujie Xue, Xue Gong, Yuye Shi, Chunling Wang, Liang Yu

    Published 2025-01-01
    “…Univariate and multivariate Cox regression analyses were used to ascertain whether CDK1 expression independently predicted DLBCL prognosis. …”
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  18. 1438

    Linking Creatinine‐to‐Body Weight Ratio With Diabetes Incidence: A Multiethnic Malaysian Cohort Study by Noraidatulakma Abdullah, Ying‐Xian Goh, Aisyatul Najihah Khuzaimi, Azwa Shawani Kamalul Arifin, Nurul Ain Mhd Yusuf, Nazihah Abd Jalal, Norliza Ismail, Nurul Faeizah Husin, Mohd Arman Kamaruddin, Rahman Jamal

    Published 2025-01-01
    “…Participants were stratified into four groups based on Cre/BW ratio quartiles. The Cox proportional hazards model evaluated the effect of Cre/BW ratio on developing incident diabetes. …”
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  19. 1439

    Refining MR-guided thermal ablation for HCC within the Milan criteria: a decade of clinical outcomes and predictive modeling at a single institution by Fu-Qun Wei, Pei-Shu Huang, Bing Zhang, Rui Guo, Yan Yuan, Jin Chen, Zheng-Yu Lin

    Published 2025-01-01
    “…Factors influencing progression-free survival (PFS) and overall survival (OS) were identified using univariate and multivariate Cox regression and stepwise regression. A nomogram was developed for survival prediction, followed by risk stratification and internal validation. …”
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  20. 1440

    Association of blood cadmium and physical activity with mortality: A prospective cohort study by Yilin Chen, Cien Zhen, Lin Zeng, Hongliang Feng, Jinyu Wang, Qi Yong H. Ai, Sizhi Ai, Jihui Zhang, Yannis Yan Liang, Huachen Xue, Yujing Zhou

    Published 2025-01-01
    “…In this prospective cohort study, a total of 20,253 participants (weighted mean age, 47.79 years), including 10,247 men (weighted prevalence: 50.1 %), aged 18 years or older, were selected from the National Health and Nutrition Examination Survey from 2007 to 2018. Multivariable Cox proportional hazards regression models were utilized to evaluate the associations between blood cadmium levels, PA, and the risks of mortality. …”
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