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1261
Association between surgery and increased survival in primary central nervous system lymphoma: a retrospective cohort study
Published 2025-01-01“…The median survival was 24.0 months for STR, 30.0 months for GTR, and 18.0 months for non-surgical patients (P < 0.001). Multivariate Cox regression analyses showed that the adjusted hazard ratio (HR) for STR was 0.77 (95% CI 0.70–0.85, P < 0.001) for overall survival (OS) and 0.74 (95% CI 0.66–0.83, P < 0.001) for cancer-specific survival (CSS). …”
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1262
Health system costs of providing outpatient care for diabetes in people with TB in the Philippines
Published 2024-03-01Get full text
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1263
Anti-Inflammatory Effects of Aster incisus through the Inhibition of NF-κB, MAPK, and Akt Pathways in LPS-Stimulated RAW 264.7 Macrophages
Published 2018-01-01“…Aster incisus also reduced significantly the production of inflammation-related enzymes (iNOS, Cox-2) and cytokines (TNFα, IL-1β, and IL-6) and the gene expression of the proinflammatory cytokines. …”
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1264
Association between lipid accumulation products and mortality outcomes in patients with osteoporosis and osteopenia
Published 2025-03-01“…Kaplan-Meier survival curves, multivariable Cox proportional hazards regression, and restricted cubic spline plots were used to evaluate the association between LAP and mortality outcomes in patients with OP or osteopenia. …”
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1265
Association between blood–urea–nitrogen-to-albumin ratio and in-hospital mortality in patients diagnosed with coronavirus disease 2019: a retrospective cohort study
Published 2025-02-01“…Methods This retrospective observational study enrolled a cohort of 1027 patients diagnosed with COVID-19 between December 2022 and March 2023. Multivariate Cox regression analyses were used to ascertain the independent association between BAR and in-hospital mortality among patients with COVID-19. …”
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1266
Factors predicting early discontinuation of methotrexate as a first-line treatment for rheumatoid arthritis in Italy: Results from the GISEA registry
Published 2019-01-01“…Baseline features of disease were evaluated by means of univariate Cox regression, and parameters significantly associated to the outcome were included in multivariate model. …”
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1267
Prevalence and outcomes associated with hypocalcaemia and hypercalcaemia among pre-dialysis chronic kidney disease patients with mineral and bone disorder
Published 2024-08-01“…Outcomes evaluated included all-cause mortality and cardiovascular events. Multivariate Cox regression analysis was done to evaluate the association of hypocalcaemia and/or hypercalcaemia with the clinical outcomes. …”
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1268
Association between alkaline phosphatase levels and mortality in Chinese patients with colorectal cancer with liver metastases: a retrospective cohort study
Published 2025-01-01“…ALP level was the primary exposure variable, with demographic, clinical and pathological factors serving as covariates. Multivariate Cox regression analyses were used to evaluate the impact of ALP on mortality over a 4-year follow-up period. …”
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1269
Role of Toll-like receptor 2 during infection of Leptospira spp: A systematic review.
Published 2024-01-01“…Notably, we observed the secretion/mRNA expression of several cytokines (IL6, IL8, IL-1β, TNFα, IFNγ, IL10, CCL2/MCP-1, CCL10, COX2, CXCL1/KC, CXCL2/MIP2) and immune effectors (hBD2, iNOS, Fibronectin, Oxygen, and Nitrogen reactive species) as key aspects of host TLR2 responses during leptospirosis. …”
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1270
Diagnosis and Prognosis of Neuroendocrine Tumours of the Lung by Means of High Resolution Image Analysis
Published 1999-01-01“…Stepwise linear discriminant analysis to differentiate the classes and Cox regression analysis for the survival time analysis were applied. …”
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1271
泛素特异性蛋白酶44在肝细胞癌中的表达及预后价值
Published 2021-09-01“…结果在161例HCC患者中,98例(60.9%)高表达USP44蛋白,Pearson′s卡方检验结果显示USP44在HCC中的表达水平与临床分期(<italic>χ<sup>2</sup></italic>=14.44,<italic>P</italic><0.001)、肿瘤单灶及多灶性(<italic>χ<sup>2</sup></italic>=8.04,<italic>P </italic>=0.005)显著相关;Kaplan-Meier分析结果显示,低表达组患者平均生存时间59.6个月,显著低于高表达组患者的平均生存时间185.0个月(Log-rank <italic>χ<sup>2</sup></italic>=20.77,<italic>P</italic><0.001);多因素Cox比例风险模型揭示USP44是HCC患者的独立预后危险因素。结论USP44蛋白高表达的HCC患者具有良好的生存期,检测其蛋白表达可作为筛选预后良好的肝细胞癌患者的一种手段。…”
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1272
Renal Complication and Glycemic Control in Korean Veterans with Type 2 Diabetes: A 10-Year Retrospective Cohort Study
Published 2020-01-01“…Participants were divided into six groups according to their baseline or dynamic HbA1c levels. Extended Cox models were used to calculate adjusted hazard ratios for the development of chronic kidney disease (CKD) and end-stage renal disease (ESRD) associated with specific HbA1c ranges. …”
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1273
Is Helicobacter pylori eradication required for non-steroidal anti-inflammatory drug-associated erosions and ulcers?
Published 2018-08-01“…Anyway, H. pylori eradication does not eliminate necessity of other methods for NSAID gastropathy prophylaxis: application of COX-2 selective inhibitors and PPI preventive prescription.…”
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1274
A Novel Insight into Paraptosis-Related Classification and Signature in Lower-Grade Gliomas
Published 2022-01-01“…Through least absolute shrinkage and selection operator regression analysis and multivariate Cox regression analysis, 10-paraptosis-related gene (PRG) signatures (CDK4, TNK2, DSTYK, CDKN3, CCR4, CASP9, HSPA5, RGR, LPAR1, and PDCD6IP) were identified to separate LGG patients into high- and low-risk subgroups successfully. …”
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1275
Common protocol for validation of the QCOVID algorithm across the four UK nations
Published 2022-06-01Get full text
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1276
The Sequence of Prostaglandin-Endoperoxide Synthase 2 Gene in Women with Cervicitis
Published 2022-11-01“…The current study aims to determine the CA125, CA 19.9, and, CA 15.3 markers level and their relationship with the COX-2 gene. Venous blood samples were obtained from 100 women with cervicitis whose ages ranged from 18 to 60 years, and 100 healthy women as a control group. …”
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1277
Neighborhood Material Deprivation Is Associated with Childhood Asthma Development: Analysis of Prospective Administrative Data
Published 2019-01-01“…We measured the risk of incident asthma using Cox proportional hazards models and the associations between ongoing asthma visits and deprivation by year of life with generalized linear mixed models. …”
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1278
The role of MRO as an M2 macrophage-associated gene in non-small cell lung cancer: insights into immune infiltration, prognostic significance, and therapeutic implications
Published 2025-01-01“…Differential gene expression and correlation studies examined MRO’s association with M2 macrophages. Univariate Cox regression and Kaplan–Meier analyses assessed prognostic significance. …”
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1279
Operative versus Nonoperative Treatment in Patients with Advanced Non-Small-Cell Lung Cancer: Recommended for Surgery
Published 2023-01-01“…NSCLC patients with stages III and IV, recommended for operation, were identified in the US National Cancer Institute Surveillance, Epidemiology, and End Results database (SEER).We used propensity score matching (PSM) and multivariable Cox proportional hazards regression to ensure the robustness of our findings. …”
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1280
Expressions and Clinical Significance of Met and YAP in Gastric Cancer Tissue Microarray
Published 2024-01-01“…Survival analysis was conducted using the Kaplan-Meier method, while multivariate survival analysis was performed using the Cox proportional hazard model. Bioinformatics analysis was carried out by downloading chip data from TCGA. …”
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