A novel cytoprotective organ perfusion platform for reconstructing homeostasis of DCD liver while alleviating IRI injury by Tingting Lan, Mingxing Yu, Tao Ming, Hong Wang, Juan Deng, Shuhan Cheng, Zhongyang Shen, Deling Kong

“…Abstract Pump is a vital component for expelling the perfusate in small animal isolated organ normothermic machine perfusion (NMP) systems whose flexible structure and rhythmic contraction play a crucial role in maintaining perfusion system homeostasis. …”
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Exploring the metabolic patterns and response mechanisms of bile acids during fasting: A study with poultry as an example by Jun Zhang, Yujie Gong, Yidan Zhu, Qingduo Zeng, Hao Zhang, Ruili Han, Yujie Guo, Donghua Li, Yadong Tian, Xiangtao Kang, Yawei Yang, Zhuanjian Li, Ruirui Jiang

“…In addition, enhanced gallbladder contraction and increased hunger were observed in laying hens during fasting. …”
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Atrial Arrhythmias in Patients with Severe COVID-19 by Kai-Yue Han, Qi Qiao, Ye-Qian Zhu, Xin-Guang Chen, Xing-Xing Kang, Gao-Feng Zhang, Xun-Chao Cai, Yong Du, Jing Jin, Ruo-Min Di, Chen-Xi Yang, Feng-Xiang Zhang, Ying-Jia Xu

“…Plasma creatine kinase isoenzyme (CKMB) levels (P=0.01) were higher in the severe group than in the nonsevere group, and there were more deaths in the severe group than in the nonsevere group (6 (15%) vs. 3 (2.30%); P=0.05). Premature atrial contractions (PAC) and nonsustained atrial tachycardia (NSAT) were significantly positively correlated with plasma CKMB levels but not with high-sensitive cardiac troponin I or myoglobin levels. …”
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Commissioning health services for First Nations, regional, and remote populations: a scoping review by Henry Boer, Janya McCalman, Chris Doran, Amanda Rush, Bridgett Mitchell, Ruth Fagan, Elizabeth Whiting, Megan Kreis, Hannah Johnson, David Lyon

“…The studies reported enabling conditions for effective commissioning including operating models that were responsive to beneficiary needs, workforce and technical capability, flexibility and duration of contracts, adequate funding, and achievable health outcomes and indicators. …”
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Post-COVID-19 conditions and health effects in Africa: a scoping review by Mustapha Amoadu, Promise Kwame Salu, David N Banaaleh, Edward W Ansah, Martin S Daanko

“…In addition to its grave effects on the global systems, there is continuation or development of new symptoms among individuals who have contracted the virus, with the potential to further stress the health systems on the continent. …”
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Noninvasive release of tendons using MRI guided focused ultrasound: a hybrid therapy using long-pulse focused ultrasound followed by thermal ablation by William Chu Kwan, Imogen den Otter-Moore, Ari Partanen, Karolina Piorkowska, Unni Narayanan, Adam C. Waspe, James M. Drake

“…The standard deviation for the area of thermal injury was also smaller for the hybrid protocol, suggesting greater predictability.Conclusion This study demonstrated a hybrid MRgFUS protocol combining long-pulse FUS followed by thermal ablation to be noninferior and safer than an ablation-only protocol for extracorporeal in-vivo tendon rupture for future clinical application for noninvasive release of contracted tendon.…”
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Epidermal stem cell derived exosomes-induced dedifferentiation of myofibroblasts inhibits scarring via the miR-203a-3p/PIK3CA axis by Shixin Zhao, Haoran Kong, Dahu Qi, Yushuang Qiao, Yu Li, Zhiming Cao, Hanwen Wang, Xuefeng He, Hengdeng Liu, Hao Yang, Suyue Gao, Tao Liu, Julin Xie

“…After in vitro and in vivo treatment with EpiSC-EVs, we assessed antifibrotic effects through scratch assays, collagen contraction assays, Western blotting, and immunofluorescence. …”
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A Review of Integrated Optimization Method of Batch Planning and Scheduling for Steelmaking-Continuous Casting-Hot Rolling Production Under Uncertain Environment Based on Lagrangia... by Liangliang Sun, Xirang Hao, Yunpeng Li, Jinghan Xue, Natalia M. Matsveichuk, Yuri N. Sotskov, Qichun Zhang

“…Its batch planning and scheduling are connected to the production contract plan at the upper level and the production process control at the lower level, which is the key to achieving efficient and full process steel manufacturing. …”
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An automated platform for simultaneous, longitudinal analysis of engineered neuromuscular tissues for applications in neurotoxin potency testing by Jacob W. Fleming, Molly C. McCloskey, Kevin Gray, David R. Nash, Vincent Leung, Christos Michas, Shawn M. Luttrell, Christopher Cavanaugh, Julie Mathieu, Shawn Mcquire, Mark Bothwell, David L. Mack, Nicholas A. Geisse, Alec S.T. Smith

“…We present a turnkey iPSC-based model of the NMJ employing channelrhodopsin-2 expression within the motor neuron (MN) population driving muscle contraction in response to blue light. MNs co-cultured with engineered skeletal muscle tissues produced twitch forces of 34.7 ± 22.7 µN in response to blue light, with a response fidelity > 92 %. …”
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Projected distribution patterns of Alpinia officinarum in China under future climate scenarios: insights from optimized Maxent and Biomod2 models by Yong Kang, Yong Kang, Fei Lin, Junmei Yin, Junmei Yin, Yongjie Han, Min Zhu, Yuhua Guo, Fenling Tang, Yamei Li

“…Through Multivariate environmental similarity surface (MESS) and most dissimilar variable (MoD) analyses revealed that increased climate variability under high emission scenarios, especially in ssp585, led to large-scale habitat contraction due to rising temperatures and unstable precipitation patterns. …”
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Coupling analysis of multi-systems urbanization: Evidence from China by Junqiang Luo, Weijing Ma, Shuang An, Zining Zhang, Yanchuan Fu, Hejun Huang, Genying Chang

“…Low-coordination cities are mainly found in the Qinghai-Tibet Plateau, Yunnan-Guizhou Plateau, the border areas of Gansu, Shaanxi, Sichuan, Chongqing, and Hubei, the Hetao area of the Yellow River Basin, the agricultural regions of the Huanghuaihai Plain, and the southeastern hilly and mountainous areas. (2) The degree of uneven urbanization development initially expands and then contracts, with intra-regional imbalances following the pattern: “Eastern Coastal Area > Northeast Area > Middle Reaches of the Yangtze River Area > Northern Coastal Area > Middle Reaches of the Yellow River Area > Southwest Area > Southern Coastal Area > Northwest Area.” (3) The coupling and coordinated development of urbanization is closely related to the economic foundation and production energy usage. …”
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Duckweed: a starch-hyperaccumulating plant under cultivation with a combination of nutrient limitation and elevated CO2 by Ling Guo, Ling Guo, Yang Fang, Songhu Wang, Yao Xiao, Yanqiang Ding, Yanling Jin, Xueping Tian, Anping Du, Zhihua Liao, Kaize He, Shuang Chen, Yonggui Zhao, Li Tan, Zhuolin Yi, Yuqing Che, Lanchai Chen, Jinmeng Li, Leyi Zhao, Peng Zhang, Zhengbiao Gu, Fangyuan Zhang, Yan Hong, Qing Zhang, Hai Zhao

“…In this study, we integrated whole-genome sequencing, epigenomics, transcriptomics, enzyme activity, and composition variation to elucidate the mechanisms of efficient starch accumulation in duckweed in terms of starch accumulation and carbon partitioning, regulation of the expression of genes in the starch metabolic pathway, and sucrose biosynthesis and transportation.Results and discussionAlthough Landoltia punctata exhibits dramatic gene family contraction, its starch content and productivity reached 72.2% (dry basis) and 10.4 g m-2 d-1, respectively, in 10 days, equivalent to a yield of 38.0 t ha-1 y-1, under nutrient limitation treatment with elevated CO2 levels. …”
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Antifungal Activity of Genistein Against Phytopathogenic Fungi <i>Valsa mali</i> Through ROS-Mediated Lipid Peroxidation by Fangjie Li, Chen Yang, Maoye Li, Su Liu, Kuo Xu, Xianjun Fu

“…Scanning electron microscopy analysis revealed that genistein caused significant changes in the structure of <i>V. mali</i>, including mycelial contraction, distortion, deformity, collapse, and irregular protrusions. …”
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Study on Mechanical Properties of Gravelly Sand under Different Stress Paths by Dongjie Zhang, Fei Luo, Zhanyuan Zhu, Jiaming Liu, Jing Li, Bailin Li, Tianlang Xue

“…We can see from the test results that gravelly sand samples show strain hardening and shear contraction under the CTC (drained), TC, and RTC during the shearing process but exhibit strain softening under the CTC (undrained). …”
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Peripheral nerve injury induces dystonia-like movements and dysregulation in the energy metabolism: A multi-omics descriptive study in Thap1+/− mice by Colette Reinhold, Susanne Knorr, Rhonda L. McFleder, Lisa Harder-Rauschenberger, Tom Gräfenhan, Andreas Schlosser, Michael Sendtner, Jens Volkmann, Chi Wang Ip

“…DYT-THAP1 dystonia is a monogenetic form of dystonia, a movement disorder characterized by the involuntary co-contraction of agonistic and antagonistic muscles. The disease is caused by mutations in the THAP1 gene, although the precise mechanisms by which these mutations contribute to the pathophysiology of dystonia remain unclear. …”
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Neuromuscular electrical stimulation training induces myonuclear accretion and hypertrophy in mice without overt signs of muscle damage and regeneration by Aurélie Fessard, Aliki Zavoriti, Natacha Boyer, Jules Guillemaud, Masoud Rahmati, Peggy Del Carmine, Christelle Gobet, Bénédicte Chazaud, Julien Gondin

“…Each NMES training session consisted of 80 isometric contractions delivered at ∼15% of maximal tetanic force to avoid muscle damage. …”
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Post COVID glaucoma service redesign utilising electronic patient triage and community optometry clinics (Fife, Scotland 2020—2022) by Niharika Nalagatla, Shameela Parveen, Kelvin KW Cheng, Caroline Styles, Andrew Blaikie, Peter Wilson, Bhavani Karri, David J Chinn, Roshini Sanders, Glaucoma Team, Lisa Wong, Alan Ramsay, Steven Halstead, Michelle Boulton, David Cummins, Colin Ferrier, Gavin Galloway, Elizabeth Embrey, Duncan Preston

“…Level one patients (482) were discharged within the Scottish general optometry service contract. Level two patients (714) were discharged to glaucoma accredited community optometry clinics. …”
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Forearm elevation impairs local static handgrip endurance likely through reduction in vascular conductance and perfusion pressure: revisiting Rohmert’s curve by L. Heinzl, S. Risse, H. Schwarzbach, O. Hildebrandt, U. Koehler, A. M. Koenig, A. H. Mahnken, R. Kinscherf, W. Hildebrandt

“…Abstract Maximal isometric contraction time (MICT) is critical for most motor tasks and depends on skeletal muscle blood flow at < 40% of maximal voluntary strength (MVC). …”
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Use of alternative payment models for substance use disorder prevention in the United States: development of a conceptual framework by Elian Rosenfeld, Sarah Potter, Jennifer Caputo, Sushmita Shoma Ghose, Nelia Nadal, Christopher M. Jones, Margaret R. Kuklinski, Andrew D. Carlo, D. Max Crowley, Lisa Clemans-Cope, Michael T. French

“…Methods In November 2023, the Substance Abuse and Mental Health Services Administration (SAMHSA), through a contract with Westat, convened an expert panel to refine a preliminary conceptual framework developed for utilizing APMs for SUD prevention and to identify strategies to encourage their adoption. …”
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Reducing men’s health drug costs: exploring the impact of the Mark Cuban Cost Plus Drug Company model on Medicare savings by Adam Khan, Karim Kari, Eli Oldham, Jacob Duncan, Matthew Rashid, Matt Vassar

“…Our study findings highlight substantial potential for cost savings if Medicare were to adjust its contracted rates to those currently set by the MCCPDC. …”
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