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A novel imatinib analogue inhibitor of chronic myeloid leukaemia: design, synthesis and characterization—explanation of its folded conformation
Published 2025-01-01“…Molecular docking studies demonstrate strong binding affinity to the ABL1 enzyme, with PAPP1 showing comparable binding energy to imatinib, indicating its potential as a lead compound for further development. Computational studies, including molecular electrostatic potential and vibrational analysis, provide further support for the structural stability and bioactivity of PAPP1. …”
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26182
Relation Between Rates of Geriatric Suicide and Consumption of Alcohol Beverages in European Countries
Published 2006-01-01“…Data on suicide rates in 65- to 74-year-olds and per capita consumption of alcoholic beverages were obtained from the World Health Organization databases. Correlations were computed to examine relationships between suicide rates in 65- to 74-year-old males and females and per capita consumption of beer, wine, and spirits in the general population in 34 European countries. …”
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26183
Incidence and Risk Factors of Postcontrast Acute Kidney Injury in Patients with Acute Ischemic Stroke
Published 2020-01-01“…Background. Multimodal computed tomography (CT) guides decision-making regarding use of thrombolytic agents in acute ischemic stroke patients. …”
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26184
E-Book Mobile Application: A Case of Kabale University Mukombe Library, Uganda
Published 2023“…However, university students find it difficult to access e-books because some of the university libraries have few computers that hold the downloaded e-books, which are stored in a folder, and little effort has been made as a result; there is low usage of e-books. …”
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26185
Food Safety Analysis of Milk and Beef in Southwestern Uganda
Published 2023“…Samples were analyzed by atomic absorbance spectrophotometer, and the EDI and ILCR were computed using the US EPA reference values. Results and Discussion. …”
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26186
Adoption of sustainable agricultural intensification practices: assessing the role of institutional and socio economic factors amongst smallholder farmers.
Published 2025“…The binomial logistic and generalized Poisson regression models were used to compute the predictor variables of adoption and adoption intensity of SAIPs respectively. …”
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26187
A Multimodal Convolutional Neural Network Based Approach for DICOM Files Classification. , 2025(1), e70107.
Published 2025“…Despite the promising results, the study acknowledges limitations in dataset diversity and computational efficiency, with future work focusing on addressing these challenges and further optimising the model for deployment in resource-limited environments.…”
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26188
E-Book Mobile Application: A Case of Kabale University Mukombe Library, Uganda
Published 2022“…However, university students find it difficult to access e-books because some of the university libraries have few computers that hold the downloaded e-books, which are stored in a folder, and little effort has been made as a result; there is low usage of e-books. …”
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26189
Impacts on and damage to European forests from the 2018–2022 heat and drought events
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Molecular and pharmacological heterogeneity of ETV6::RUNX1 acute lymphoblastic leukemia
Published 2025-01-01Get full text
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26192
Measúnú ar Ionphlandú Téarmaí Teicneolaíochta Faisnéise agus Cumarsáide sa Ghaeilge: Cur chuige corpasbhunaithe [Assessing the Implantation of ITC Terms in Irish: A corpus-based ap...
Published 2024-11-01“…This paper deals with a research project to evaluate the implantation of information and communication technology terms in written Irish by searching in a corpus of computing texts. The corpus-based methodology was based on Quirion's (2003) standard research protocol, a recognised approach to measuring terminology implantation. …”
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A Security Authentication Protocol for Trusted Domains in an Autonomous Decentralized System
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