-
301
Hepatitis in Disseminated Bacillus Calmette-Guérin Infection
Published 2000-01-01“…Empirical treatment was started with antituberculous combination therapy. A short course of an oral corticosteroid was given. …”
Get full text
Article -
302
Prognostic impact of primary versus secondary resistance to sorafenib in patients with HCC
Published 2025-01-01“…Compared with tyrosine kinase inhibitor (TKI) monotherapy, the use of TKI plus PD-1 inhibitor combination therapy as second-line treatment conferred a longer median PFS (6.0 vs 10.0 months, p < 0.001) and OS (13.0 vs 22.0 months, p < 0.001). …”
Get full text
Article -
303
Management of asynchronous multifocal adult glioblastoma with loss of BRAFV600E -mutant clonality: a case report
Published 2025-01-01“…Subsequent recurrences were managed with re-resection and dabrafenib/trametinib combination therapy. Notably, a new, non-clonal BRAFV600E -negative tumor developed in a distant location, highlighting the challenge of clonal evolution and resistance in GBM management. …”
Get full text
Article -
304
Regenerative Medicine for Neurological Disorders
Published 2010-01-01“…A number of studies focused on novel methods for drug monitoring or graft tracking, and combination therapy with stem cells and medicine, such as cytokines or trophic factors. …”
Get full text
Article -
305
Sirolimus Enhances Cyclosporine A-Induced Cytotoxicity in Human Renal Glomerular Mesangial Cells
Published 2012-01-01“…These synergistic alterations may have been due to an increase in CTGF which was not evident when the immunosuppressive drugs were used alone. The CsA/SRL combination therapy significantly enhanced Smad signalling and altered the extracellular matrix regulator matrix metalloproteinase 9 (MMP-9). …”
Get full text
Article -
306
Pulmonary and Meningeal Cryptococcosis after Corticosteroid Therapy for Autoimmune Hepatitis: Coexistence of Cryptococci within Pulmonary Cancer Nodule
Published 2013-01-01“…Cryptococcal meningitis was diagnosed as positive for cryptococcal antigen from both serum and cerebrospinal fluid (CSF) as well as the growth of Cryptococcus neoformans (C. neoformans) in fungal culture. A combination therapy of amphotericin B and flucytosine was started, and the corticosteroid therapy was gradually reduced and finally discontinued. …”
Get full text
Article -
307
Association of Serum CXCL13 with Intrarenal Ectopic Lymphoid Tissue Formation in Lupus Nephritis
Published 2016-01-01“…LN patients with positive CD20 expression (CD20+ LN) had a longer disease course and poorer response to combination therapy and higher serum CXCL13 levels than CD20− LN patients. …”
Get full text
Article -
308
Clinical efficacy of different methods for treatment of granulomatous lobular mastitis: A systematic review and network meta-analysis.
Published 2025-01-01“…<h4>Conclusions</h4>Steroid-based combination therapy may be the first choice for IGM patients, with a comprehensive strategy of local and systemic steroids combined with surgery having the best effect on IGM.…”
Get full text
Article -
309
Features of conservative therapy of benign prostatic hyperplasia in patients with metabolic syndrome: " Treat to Target "
Published 2020-12-01“…A direct correlation was established between the severity of metabolic disorders and the progression of BPH /LUTS in the main assessed indicators. The use of combination therapy with metformin, ACE inhibitors / ARA and statins in combination with tamsulosin showed efficacy after 6 and 12 months of the study compared with tamsulosin monotherapy. …”
Get full text
Article -
310
Hotspots evolution and frontiers of immunotherapy for the treatment of acute myeloid leukemia: A bibliometric analysis
Published 2025-12-01“…The current research hotspots of AML immunotherapy included chimeric antigen receptor-T-cell therapy, antibody-based immunotherapies, immune checkpoint blockade, and combination therapy, highlighting the key aspects of immunotherapy for AML treatment and providing comprehensive insights into the research status and advances in this field. …”
Get full text
Article -
311
ALLERGIC RHINITICAL THERAPY WITH ACUPUNCTURE, LEGUNDI AND TEMULAWAK HERBS
Published 2019-01-01“…Purpose: To prove the effect of acupuncture combination therapy on Yintang point (EXHN 3), Yinxiang (LI 20), Zusanli (ST 36), Taibai (SP 3) with herbal legundi (Vitex trifolia) and temulawak (Curcuma xanthorrhiza) in patients with allergic rhinitis. …”
Get full text
Article -
312
Epidemiological, Clinical and Paraclinical Profile of Paediatric Malaria at University Hospital Centre Amissa Bongo in Franceville, Gabon
Published 2024-12-01“…The majority of children were treated for simple malaria with artemisinin-based combination therapy. A total of 16/53 was seen in post-therapeutic consultation. …”
Get full text
Article -
313
ErbB- and MUC1-targeted CAR-T cell immunotherapy of oral squamous cell carcinoma
Published 2023-03-01“…Potential strategies including combination therapy, utilising both TAA-targeting CAR-Ts and immune checkpoint inhibitors, such as PD-L1, have been discussed, in an attempt to develop synergistic anti-tumour responses. …”
Get full text
Article -
314
In Vivo and In Vitro Studies Assessing the Antiviral Efficacy of Double Combinations Against Coxsackievirus B Infection
Published 2025-01-01“…Drug therapy is an important tool for controlling enterovirus infections, but clinically effective drugs do not currently exist, mainly due to the development of drug resistance. Combination therapy with two or more drugs has the potential to successfully inhibit viral infection more effectively than either drug alone as well as delay the development of resistance. …”
Get full text
Article -
315
Brucellosis Presenting with Febrile Pancytopenia: An Atypical Presentation of a Common Disease and Review of Brucellosis
Published 2021-01-01“…Treatment involves a prolonged course of multiple antibiotics; six weeks of combination therapy with aminoglycoside or rifampin and tetracycline represents the most common regimen. …”
Get full text
Article -
316
Targeting the kynurenine pathway: another therapeutic opportunity in the metabolic crosstalk between cancer and immune cells
Published 2025-01-01“…In Phase III investigation of the combination of IDO1 inhibition with immune checkpoint inhibitors (ICIs), the combination therapy was not efficacious. In this review, we revisit current advances, explore future directions, and emphasize the importance of dual inhibition of the KP rate-limiting enzymes IDO1 and tryptophan 2,3-dioxygenase-2 (TDO2) in appropriate patient populations. …”
Get full text
Article -
317
Antibacterial action of penicillin against Mycobacterium avium complex
Published 2024-08-01“…CONCLUSIONS: Benzylpenicillin demonstrated a better bactericidal effect against MAC than guideline-recommended drugs before the development of resistance. Its role in combination therapy with other drugs with better efficacy than guideline-recommended drugs should be explored.…”
Get full text
Article -
318
MicroRNA in Cervical Cancer: OncomiRs and Tumor Suppressor miRs in Diagnosis and Treatment
Published 2014-01-01“…Previous approaches to development of siRNA as a drug have provided information for establishment of therapy based on these approaches, and an anti-miR-21 inhibitor has been developed. miRNAs also have effects on drug resistance and may be useful in combination therapy with other drugs.…”
Get full text
Article -
319
Conductive Composite Biosensor System for Electrochemical Indinavir Drug Detection
Published 2015-01-01“…Indinavir undergoes first-pass metabolism through the cytochrome P450 (CYP) enzymes in the human liver, of which CYP3A4 is the most influential isoenzyme. Multidrug combination therapy and, as such, therapeutic drug monitoring (TDM) during HIV/AIDS treatment are therefore critical, to prevent adverse interactions. …”
Get full text
Article -
320
Surgical Excision and Radiotherapy for Giant Keloids in Auricula: A Case Report
Published 2025-01-01“…Therefore, this study aimed to report combination therapy for patients with giant keloids in auricula. …”
Get full text
Article