Case report: Complete response of recurrent locally advanced basal cell carcinoma following addition of vismodegib to neoadjuvant cemiplimab therapy by Chalette Lambert-Swainston, Wolfram Samlowski, Wolfram Samlowski, Wolfram Samlowski, Brandon Reynolds, Amin Hedayat, Amin Hedayat

“…Further evaluation of cemiplimab and hedgehog inhibitor combination therapy in la BCC appears warranted.…”
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Reversible Pulmonary Arterial Hypertension Associated with Interferon-Beta Treatment for Multiple Sclerosis by E Gibbons, S Promislow, RA Davies, G Chandy, DJ Stewart, V Contreras-Dominguez, C Pugliese, R Dunne, LM Mielniczuk

“…The patient experienced significant clinical and hemodynamic improvement, with normalization of her pulmonary pressures after the initiation of combination therapy for PAH. At 28 months after diagnosis, she remains asymptomatic with no hemodynamic evidence of PAH and has been off all PAH therapy for 10 months.…”
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Severe Myositis, Myocarditis, and Myasthenia Gravis with Elevated Anti-Striated Muscle Antibody following Single Dose of Ipilimumab-Nivolumab Therapy in a Patient with Metastatic M... by Mahdieh Fazel, Patrick M. Jedlowski

“…A case of a 78-year-old woman with metastatic melanoma status after combination therapy with ipilimumab-nivolumab that developed transaminitis, myositis, myocarditis, and myasthenia gravis (with positive anti-striational antibodies) five days after the first cycle, is presented. …”
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THERAPY FOR HYPERTENSION WITH ACUPUNTURE AND HERBAL CUCUMBER (Cucumis sativus (L.)) by Yuninda Asyroful Kamaliyah, Ario Imandiri, Myrna Adianti

“…Purpose: To determine the effect of acupuncture combination therapy at Shenmen (HT 7), Fuliu (KI 7), Taichong (LR 3), Xingjian (LR 2), and Yinlingquan (SP 9) herbal fruit and herbal cucumber (Cucumis sativus) in diseases hypertension. …”
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The Curative and Prophylactic Effects of Xylopic Acid on Plasmodium berghei Infection in Mice by J. N. Boampong, E. O. Ameyaw, B. Aboagye, K. Asare, S. Kyei, J. H. Donfack, E. Woode

“…Efforts have been intensified to search for more effective antimalarial agents because of the observed failure of some artemisinin-based combination therapy (ACT) treatments of malaria in Ghana. …”
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IRREGULAR MENSTRUATION THERAPY WITH ACUPUNCTURE, POMEGRANATE PEEL AND GINGER HERBS by Sinta Diyah Dimyati, Suhariningsih Suhariningsih, Nurmawati Fatimah

“…Purpose: To determine the effect of acupuncture combination therapy at the Taichong (LV3), Sanyinjiao (SP6), Diji (SP8) and Qihai (CV6) point with herbal pomegranate peel (Punica granatum L.) and ginger (Zingiber officinale Rosc.) in irregular menstrual patients. …”
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Nose to brain strategy coupled to nano vesicular system for natural products delivery: Focus on synaptic plasticity in Alzheimer's disease by Nunzia Maisto, Dalila Mango

“…The combination of nano vesicular systems, as colloidal systems, and nose to brain (NtB) delivery depicts a new nanotechnological strategy to overtake this limit and to develop new treatment approaches for brain diseases, including the use of natural molecules in combination therapy for AD. Herein, we will provide an updated overview, examining the literature of the last 20 years and using specific keywords that provide evidence on natural products with the ability to restore synaptic plasticity alterations in AD models, and the possible application using safe and non-invasive strategies focusing on nano vesicular systems for NtB delivery.…”
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Permeation Peptide Conjugates for In Vivo Molecular Imaging Applications by Kristin E. Bullok, Seth T. Gammon, Stefania Violini, Andrew M. Prantner, Victor M. Villalobos, Vijay Sharma, David Piwnica-Worms

“…These novel permeation peptide conjugates maintain rapid translocation across cell membranes into intracellular compartments and have the potential for targeted in vivo applications in molecular imaging and combination therapy.…”
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Natural products as part of triple negative breast cancer by Yozlem Kobakova, Maria Moneva-Sakelarieva, Spiro Konstantinov, Georgi Momekov, Stefka Achkova Ivanova, Ventseslava Atanasova, Maria Chaneva, Radoslav Tododrov, Nikolay Bashev, Petar Atanasov

“…More and more research in this field is focused on single or combination therapy based on compounds obtained from natural sources. …”
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Effectiveness of acupuncture on glycolipid metabolism in patients with coronary heart disease: A systematic review and meta-analysis by Yuxin Sun, Yu Liu, Jian Xiong, Xiao Li, Ying Wei, Qianhua Zheng, Xiang Li, Wenchuan Qi, Fanrong Liang

“…For secondary outcome measures, combination therapy improved TC (SMD = −0.97; 95 % CI, −1.44 to −0.51; P < 0.0001), TG (MD = −0.39; 95 % CI, −0.58 to −0.20; P < 0.0001), hs-CRP (MD = −0.98; 95 % CI, −1.43 to −0.52; P <0.0001), 2hPG (MD = −1.45; 95 % CI, −1.74 to −1.16; P < 0.00001), and ORR (RR, 1.27; 95 % CI, 1.19–1.36; P < 0.00001) levels more than standard therapy alone.However, the combination therapy did not prevail in lowering HDL-C (MD = 0.11; 95 % CI, 0.07–0.14; P < 0.00001) compared with standard therapy alone. …”
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First-in-human phase 1 dose-escalation results with livmoniplimab, an antibody targeting the GARP:TGF-ß1 complex, as monotherapy and in combination with the anti–PD-1 antibody budi... by Toshio Shimizu, Toshio Shimizu, John Powderly, Albiruni Abdul Razak, Patricia LoRusso, Kathy D. Miller, Steven Kao, Sarah Kongpachith, Catherine Tribouley, Michelle Graham, Brian Stoll, Maulik Patel, Mohammad Sahtout, Martha Blaney, Rachel Leibman, Talia Golan, Talia Golan, Anthony Tolcher

“…The most common adverse events reported in monotherapy-treated patients were fatigue, anemia, and nausea, and those in combination therapy-treated patients were pruritus, fatigue, nausea, and anemia. …”
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Advancements in managing chemotherapy-induced nausea and vomiting: From efficacy to cost-effectiveness by Yuvashree Chandrasekaran, Mukesh Kumar Dharmalingam Jothinathan

“…A review of the available research indicates that there are specific kinds of treatment therapies that are effective as well as inexpensive such as netupitant and palonosetron combination therapy. With tropisetron along with dexamethasone acting as first choice for controlling CINV symptoms, especially though cisplatin, the superior CINV control is ensured for both acute and delayed symptoms. …”
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The role of mitochondrial dysfunction in the cytotoxic synergistic effect of gemcitabine and arsenic on breast cancer. by Farshid Maleki, Somayeh Handali, Mohsen Rezaei

“…To the best of our knowledge, this is the first study showing promising results for combination therapy with ATO and GCB in breast cancer.…”
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THERAPY LOW BACK PAIN WITH SWEDISH MASSAGE, ACUPRESSURE AND TURMERIC by Dyah Ayu Rhomandhoni Putri, Ario Imandiri, Rakhmawati Rakhmawati

“…Purpose: To prove the effect of combination therapy for Swedish massage in the back and waist area, acupressure at Shenshu (BL23), Dachangshu (BL25), Taixi (KI3), Taibai (SP3), Fenglong (ST40) and turmeric herbs (Curcuma longa Linn) on low back pain sufferers. …”
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Effect of an “Autogenous Leukocyte Platelet-Rich Fibrin Tooth Graft” Combination around Immediately Placed Implants in Periodontally Compromised Sites: A Randomized Clinical Trial... by Walid ElAmrousy, Dalia Rasheed Issa

“…The ATBG- L-PRF combination therapy enhances new bone formation and appeared to be a favorable procedure with immediate implant placement, particularly in severe periodontitis cases.…”
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Microneedling in Combination with Topical Pimecrolimus 1% versus Topical Pimecrolimus 1% for the Treatment of Refractory Stable Vitiligo: A Randomized Clinical Trial by Fariba Iraji, Ali Asilian, Zahra Talebzadeh, Mina Saber, Fatemeh Mokhtari, Amirhossein Siadat, Seyed Mohsen Hosseini

“…This study established that combination therapy results in more significant patient improvement. …”
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Efficacy of Telmisartan Plus Amlodipine in Nonresponders to CCB Monotherapy by Steen Neldam, Dingliang Zhu, Helmut Schumacher

“…Early use of such combination therapy should be considered to quickly reach BP targets, particularly in patients with added risk.…”
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Amodiaquine and Ciprofloxacin Combination in Plasmodiasis Therapy by Peace Mayen Edwin Ubulom, Chinweizu Ejikeme Udobi, Mark Iheukwumere Madu

“…Conversely, the combination therapy of Amodiaquine and Ciprofloxacin had a significant antiplasmodial effect at all the doses administered. …”
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The combination treatment of RC48 and STAT3 inhibitor acts as a promising therapeutic strategy for basal bladder cancer by Jingxian Li, Kun Shan, Wei Huang, Qiang Su, Yuanjiong Qi, Zhihong Zhang, Jianqiang Zhu, E. Du

“…In our study, we aim to explore sensitivity differences and mechanisms of different molecular subtypes of MIBC to RC48 treatment and develop a strategy for combination therapy against cancer. Using large-scale mRNA expression profile datasets, Western blotting, and immunohistochemistry, we first found that ERBB2 is upregulated in the luminal type but downregulated in basal bladder cancer. …”
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Lifestyle and behavioral interventions for urinary incontinence in frail older adults: An integrative review of recent evidence by Kristine M.C. Talley, Janie Thompson

“…The most evidence existed for prompted voiding and individualized combination therapy that includes functional training. Discussion:: Frail older adults are rarely included in research on lifestyle and behavioral interventions for incontinence and are overlooked in clinical practice guidelines. …”
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