Showing 1,801 - 1,820 results of 3,119 for search '"colony"', query time: 0.09s Refine Results
  1. 1801
  2. 1802

    L’aqueduc de Fontanières : un cinquième aqueduc romain à Lyon ? by Jean-Yves Barbier

    Published 2023-12-01
    “…In France, the Fourvière promontory, the original founding site of the Roman colony of Lyon/Lugdunum (Metropolis of Lyon), extends southwards into the line of hills that was left behind by the Alpine glaciers of the Lyon plateau, marking the steep eastern edge of the Massif Central at its point of contact with the Rhone Graben and river valley. …”
    Get full text
    Article
  3. 1803

    Repurposing the prostaglandin analogue treprostinil and the calcium-sensing receptor modulator cinacalcet to revive cord blood as an alternate source of hematopoietic stem and prog... by Michaela Prchal-Murphy, Julia Zehenter, Marlene Fischer, Anita Pirabe, Madeleine Themanns, Behnaz Afrashteh, Eva Maria Putz, Karoline Kollmann, José Basílio, José Basílio, Manuel Salzmann, Wolfgang Strohmaier, Günther Krumpl, Alex Farr, Veronika Sexl, Michael Freissmuth, Eva Zebedin-Brandl

    Published 2025-01-01
    “…In vitro assays demonstrated enhanced migration and adhesion in response to the presence of treprostinil and cinacalcet, suggesting potential synergistic effects. Colony formation confirmed synergism.ConclusionAugmenting the bone marrow reconstitution potential of HSPCs with treprostinil and cinacalcet shows promise for rescuing patients undergoing HCT. …”
    Get full text
    Article
  4. 1804

    Gut microbiota derived DCA enhances FOLFOX efficacy via Ugt1a6b mediated enterohepatic circulation in colon cancer by Qian Fang, Xiaoying Hou, Limei Fan, Yufei Deng, Xiaoxuan Li, Hongyun Zhang, Haiping Wang, Zhengqi Fu, Binlian Sun, Xiji Shu, Hongzhi Du, Yuchen Liu

    Published 2025-03-01
    “…Further, based on the system screen of 15 bile acids on FOLFOX efficacy via MTT, colony formation and flow cytometry assay, Deoxycholic Acid (DCA) and Glycodeoxycholic Acid (GDCA) were annotated as potential modulators of FOLFOX efficacy. …”
    Get full text
    Article
  5. 1805

    Vingt années de recherches à Oedenburg (Biesheim et Kunheim, Haut-Rhin) : un bilan by Michel Reddé

    Published 2019-12-01
    “…The recent and widely diffused identification of Oedenburg with the “polis” of Argentovaria, considered as an indigenous capital of Rauraques, beside the Roman colony, thus appears to be very dubious.The wetland zones were conducive to archaeobotanical studies, which showed the importance of Roman military presence through the identification of an association of plants from the Mediterranean or even further away. …”
    Get full text
    Article
  6. 1806

    Metabolically activated and highly polyfunctional intratumoral VISTA+ regulatory B cells are associated with tumor recurrence in early-stage NSCLC by Domenico Lo Tartaro, Beatrice Aramini, Valentina Masciale, Nikolaos Paschalidis, Francesco Demetrio Lofaro, Anita Neroni, Rebecca Borella, Elena Santacroce, Alin Liviu Ciobanu, Anna Valeria Samarelli, Federica Boraldi, Daniela Quaglino, Alessandra Dubini, Michele Gaudio, Gloria Manzotti, Francesca Reggiani, Federica Torricelli, Alessia Ciarrocchi, Antonino Neri, Federica Bertolini, Massimo Dominici, Pier Luigi Filosso, Franco Stella, Lara Gibellini, Sara De Biasi, Andrea Cossarizza

    Published 2025-01-01
    “…VISTA+ Bregs displayed high metabolic demand and were able to produce different cytokines, including interleukin (IL)-10, transforming growth factor (TGF)-β, IL-6, tumor necrosis factor (TNF), and granulocyte–macrophage colony-stimulating factor (GM-CSF). Spatial analysis showed colocalization of B cells with CD4+/CD8+ T lymphocytes in TME. …”
    Get full text
    Article
  7. 1807

    Early bactericidal activity of sitafloxacin against pulmonary tuberculosis by Lihui Nie, Jing Tong, Guihui Wu, Juan Du, Yuanyuan Shang, Yufeng Wang, Zhangjun Wu, Yuanhong Xu, Yi Ren, Youyi Rao, Yu Pang, Mengqiu Gao

    Published 2025-01-01
    “…Sputum for quantitative culture was collected 2 days before the study of drug administration, followed by 16 hours of overnight sputum collected daily for 7 days of monotherapy. Colony-forming units (CFU) of Mycobacterium tuberculosis were counted from the collected overnight sputum on agar plates to calculate the EBA, defined as log10 CFU/mL sputum/day. …”
    Get full text
    Article
  8. 1808

    Creation of body color mutants by CRISPR/Cas9 gene editing in largemouth bass, Micropterus salmoides by Lina Sun, Tian Gao, Zhiqiang Li, Xiaolong Yang, Zuliang Qin, Mingxiao Ye, Ying Li, Feilong Wang, Deshou Wang

    Published 2025-03-01
    “…The fertilized eggs were obtained through hormonal induction (5 μg/kg LHRH-A3, 600 IU/kg hCG and 2 mg/kg DOM) and artificial insemination, and the tyrb (tyrosinase b) or csf1ra (colony-stimulating factor 1 receptor a) gRNA and Cas9 mRNA were microinjected into the fertilized eggs at the one-cell stage for targeted gene editing. …”
    Get full text
    Article
  9. 1809

    Klebsiella pneumoniae induces dose-dependent shock, organ dysfunction, and coagulopathy in a nonhuman primate critical care model by Jeffrey R. Strich, Marcos J. Ramos-Benitez, Seth Warner, Heather Kendall, Sydney Stein, Andrew P. Platt, Sabrina C. Ramelli, Shelly J. Curran, Izabella Lach, Kiana Allen, Ashley Babyak, Luis J. Perez-Valencia, Mahnaz Minai, Junfeng Sun, Kevin M. Vannella, Derron Alves, Richard Herbert, Daniel S. Chertow

    Published 2025-01-01
    “…Neutrophil activation evidenced by increased CD11b expression, decreased CD62L expression, and increased circulating levels of myeloperoxidase, lactoferrin, and neutrophil extracellular traps; monocyte activation evidenced by increased circulating levels of interleukin-6, tumor necrosis factor-alpha, granulocyte-macrophage colony-stimulating factor, and monocyte chemotactic protein-1; and endothelial activation evidenced by increased circulating levels of syndecan-1 and angiopoietin-II were all consistent with human sepsis. …”
    Get full text
    Article
  10. 1810

    Brucea javanica oil inhibited the proliferation, migration, and invasion of oral squamous carcinoma by regulated the MTFR2 pathway by Yihan Lai, Yihan Lai, Mingkang Li, Mingkang Li, Juan Zhan, Juan Zhan, Lin Jiang, Lin Jiang, Yuan Wu, Zhiyi Fang, Jianhan Zhou, Jianhan Zhou, Yujie Ma, Yisen Shao, Yisen Shao, Wei Wang, Wei Wang

    Published 2025-01-01
    “…Studies have shown that Brucea javanica oil (BJO) extracts have anti-cancer effects against a variety of cancers, but little research has been reported on OSCC. MethodsCCK8, Colony formation, Scratch test and Transwell invasion assays were applied to determine the effects of BJO on the proliferation, migration, and invasion ability of OSCC cells in vitro. …”
    Get full text
    Article
  11. 1811
  12. 1812

    Preclinical pharmaco-toxicological screening of biomimetic melanin-like nanoparticles as a potential therapeutic strategy for cutaneous melanoma by Iasmina Marcovici, Iasmina Marcovici, Raul Chioibas, Raul Chioibas, Istvan Zupko, Iulia Pinzaru, Iulia Pinzaru, Alina Moaca, Alina Moaca, Adriana Ledeti, Adriana Ledeti, Lucian Barbu-Tudoran, Lucian Barbu-Tudoran, Andreea Geamantan, Andreea Geamantan, Iasmina Predescu, Iasmina Predescu, Cristina Adriana Dehelean, Cristina Adriana Dehelean

    Published 2025-02-01
    “…The cytotoxic, anti-migratory, anti-clonogenic, pro-oxidant and pro-apoptotic properties of MEL-NPs were investigated in vitro by applying the MTT viability test, bright-field and immunofluorescence microscopy, DCFDA/H2DCFDA test, scratch assay, colony formation assay, and RT-qPCR. The irritant and anti-angiogenic effects were assessed in ovo on the vascularized chorioallantoic membrane (CAM).ResultsThe as-made MEL-NPs presented a spherical morphology, an average size of 85.61 nm, a broad UV-VIS absorption spectrum, and a strong antioxidant activity. …”
    Get full text
    Article
  13. 1813
  14. 1814

    Pulmonary fibrosis in patients with autoimmune pulmonary alveolar proteinosis: a retrospective nationwide cohort study by Yoann Guirriec, David Luque-Paz, Gontran Bernard, Axelle Mabo, Mallorie Kerjouan, Cédric Ménard, Delphine Monnier, Hilario Nunes, Yurdagül Uzunhan, Martine Reynaud-Gaubert, Julien Bermudez, Raphaël Borie, Bruno Crestani, Julie Traclet, Lidwine Wémeau-Stervinou, Cécile Chenivesse, Emmanuel Gomez, Grégoire Prévot, Arnaud Bourdin, Benjamin Bondue, Anne Bergeron, Vincent Cottin, Mathieu Lederlin, Stéphane Jouneau

    Published 2024-12-01
    “…Dust exposure was associated with pulmonary fibrosis occurrence (OR 4.3; p=0.038). aPAP patients treated with whole-lung lavage, rituximab or granulocyte–monocyte colony-stimulating factor therapy did not have more fibrotic evolution than patients who did not receive these treatments (n=25 out of 45, 57% versus n=10 out of 16, 62%; p=0.69). …”
    Get full text
    Article
  15. 1815

    Newly identified c-di-GMP pathway putative EAL domain gene STM0343 regulates stress resistance and virulence in Salmonella enterica serovar Typhimurium by Kaifeng Chen, Lili Li, Nanwei Wang, Zhouping Zhou, Peng Pan, Chenggang Xu, Dage Sun, Jiayi Li, Changzhi Dai, Dai Kuang, Ming Liao, Jianmin Zhang

    Published 2025-01-01
    “…As a result, the biofilm formation ability of 269ΔSTM0343 was enhanced by 21.54%, accompanied by a more pronounced red, dry, and rough colony morphology. 269ΔSTM0343 also showed a 19.03% decrease in motility due to the downregulation of flhD expression. …”
    Get full text
    Article
  16. 1816

    Alimentation et gestion de l’eau sur la colline de Fourvière à Lyon : les aménagements hydrauliques, la ville et ses monuments by Aldo Borlenghi, Éric Leroy

    Published 2023-12-01
    “…On Fourvière hill, which reaches a maximum altitude of about 298 m NGF, the public buildings, thermal baths, fountains, reservoirs as well as the houses and private amenities were supplied with water by the four Lyon aqueducts.The constraints caused by the topography of the hill on which the Roman colony was established made it difficult to supply the districts located in the highest part of the hill, in particular those located above 270 m. …”
    Get full text
    Article
  17. 1817
  18. 1818

    GM-CSF and IL-21-armed oncolytic vaccinia virus significantly enhances anti-tumor activity and synergizes with anti-PD1 immunotherapy in pancreatic cancer by Yujing Xuan, Wenyi Yan, Ruimin Wang, Xibin Wang, Yu Guo, Huilin Dun, Ziyan Huan, Lihua Xu, Ruxia Han, Xianlei Sun, Lingling Si, Nicholas R. Lemoine, Nicholas R. Lemoine, Yaohe Wang, Yaohe Wang, Pengju Wang

    Published 2025-01-01
    “…Then, VVL-DD was armed with an optimal combination of immunomodulatory molecules, granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-21 (IL-21), to produce VVL-GL21. …”
    Get full text
    Article
  19. 1819

    The dynamics of African indigenous knowledge systems : a sustainable alternative for livelihoods in southern Africa /

    Published 2022
    Table of Contents: “…Introduction: The dynamics of indigenous knowledges and sustainable livelihoods in Africa / Edward Shizha and Christopher Ndlovu -- Mainstreaming and investing in indigenous knowledge epistemologies for sustainable livelihoods / Edward Shizha -- Buttressing sustainable security systems through African indigenous epistemologies / Shepherd Ndondo and Christopher Ndlovu -- Harnessing indigenous conflict resolution processes in building sustainable communities / Mandlenkosi Ndlovu -- Participation of diasporas in building sustainable communities in Zimbabwe: Implementation of Ubuntu philosophy / Roland Moyo, Christopher Ndlovu and Edward Shizha -- The role of indigenous knowledge systems in sustainable adaptation to climate change / Tinashe Pikirai -- Understanding climate change adaptation for increased productivity and sustainability in Southern African communities: A review / Keith Phiri -- Implementing indigenous knowledge systems for sustainable learning in African primary schools / Emily Mangwaya and Ezron Mangwaya -- Integration of indigenous mathematical knowledge into the mathematics education for sustainable learning / Nhlanhla Mkwelie, Ntandoyenkosi Satamwe and Edward Shizha -- Embedding sustainability and Ubuntu philosophy in the learning of learners with disruptive behaviours / Mlungisi Moyo -- Language of instruction imbroglio in the post-colonial school curriculum (Zimbabwe Curriculum Framework, 2015-2020): The obstacle to sustainable learning / Otildah S. …”
    View in OPAC
    eBook
  20. 1820

    Le réseau hydraulique à Pompéi (Italie) de l’époque des Samnites à Auguste (fin ive-fin ier s. av. J.-C.) by Federico Giletti

    Published 2023-12-01
    “…While it is true that the decision to install chambered cisterns to regulate the slope of the hillside may have served to enlarge the building spaces, it is equally plausible that their purpose was also to provide the city wall defences with water reserves to supply the militia in case of siege or fire, in accordance with a common practice in ancient urban design.The military value of some of these cisterns, however, lost its significance after the establishment of the colony, as did walled fortifications. For this reason, the growing tendency to build sumptuous dwellings, with an enviable viewpoint overlooking the Sarno plain below, led to buildings being extended above and beyond the defensive walls, even reusing structural parts that were no longer considered necessary.In the same way, many of the cisterns behind them lost their function, being converted into rooms in the house or used as stairways or corridors.The large basins seem to have retained their function until the advent of the aqueduct system, introduced in Pompeii in the Augustan age. …”
    Get full text
    Article