Predicting the effectiveness of omalizumab in patients with refractory chronic rhinosinusitis with nasal polyps comorbid with asthma based on inflammatory biomarkers by Yutong Sima, MD, Ming Zheng, MD, Yan Zhao, PhD, Siqi Ge, PhD, Chengyao Liu, MD, Ping Wang, BS, Xiangdong Wang, MD, PhD, Luo Zhang, MD, PhD

“…The concentrations of T2 inflammatory biomarker, granulocyte-macrophage colony-stimulating factor (GM-CSF), T3 inflammatory biomarkers, granulocyte colony-stimulating factor (G-CSF), chemokine (C-X-C motif) ligand (CXCL)-1, and chemokine (C–C motif) ligand-20 (CCL-20), T1 inflammatory biomarker, IP-10 (CXCL-10), and granzyme B in nasal secretion and serum periostin were significantly decreased. …”
Get full text

Differential Reponses of Hematopoietic Stem and Progenitor Cells to mTOR Inhibition by Aimin Yang, Xia Xiao, Mingfeng Zhao, Amanda C. LaRue, Bradley A. Schulte, Gavin Y. Wang

“…Here we report that dual inhibition of mTORC1/2 by AZD or its analogue (KU-63794) depletes mouse BM Lin−Sca-1+c-Kit+ cells in cultures via the induction of apoptotic cell death. Subsequent colony-forming unit (CFU) assays revealed that inhibition of mTORC1/2 suppresses the clonogenic function of hematopoietic progenitor cells (HPCs) in a dose-dependent manner. …”
Get full text

Interaction of STIL with FOXM1 regulates SF3A3 transcription in the hepatocellular carcinoma development by Haijun Zhang, Lin Zhang, Ziqi Wu

“…Changes in malignant behavior of HCC cells after downregulation of SF3A3 were assessed by EdU, colony formation, flow cytometry, wound healing, and Transwell invasion assays. …”
Get full text

Bacteriospermia and Sperm Quality of Cryopreserved Bull Semen Used in Artificial Insemination of Cows in South Wollo Zone, Ethiopia by Abadi Amare Reda, Gizat Almaw, Solomon Abreha, Wedajo Tadeg, Belege Tadesse

“…Overall average bacterial load of 50.38 ± 16.29 colony-forming units (CFU)/ml (from nil to 1318.20 CFU/ml) was found. …”
Get full text

Deformation-induced pearlite transformation and spheroidization of bearing steel for new energy vehicles by Zhihui Chen, Xiaolong Gan, Man Liu, Zhengliang Xue, Hao Tian, Desheng Li, Guang Xu

“…EBSD results show that with increasing the deformation strain, the size of pearlite colony decreased, the size of pearlite nodules, and the proportion of high-angle grain boundaries decreased first and then increased. …”
Get full text

Secretory Leukocyte Protease Inhibitor Is an Inducible Antimicrobial Peptide Expressed in Staphylococcus aureus Endophthalmitis by Victor E. Reviglio, Ruben H. Sambuelli, Alejandra Olmedo, Micaela Falco, Jose Echenique, Terrence P. O'Brien, Irene C. Kuo

“…Seventy-five female Lewis rats were divided into three groups: the endophthalmitis group received an intravitreal injection of 65 colony-forming units of viable S. aureus, the vehicle-injected group received balanced sterile saline solution (BSS), and the control group was not injected. …”
Get full text

Occurrence and Antibiotic Resistance of Mesophilic Aeromonas in Three Riverine Freshwaters of Marrakech, Morocco by Boujamaa Imziln

“…Average counts of Aeromonas in low and heavily polluted waters were 2.5 × 103 and 2.1 × 106 colony forming units per 100 ml, respectively. The biochemical identification of 841 isolates indicated a predominance of A. caviae in heavily and moderately polluted water and sediment. …”
Get full text

Optimizing Photovoltaic Panel Performance: A Comparative Study of Meta-Heuristic Algorithms by M. Sundar Rajan

“…This method was compared against other well-known algorithms such as Artificial Bee Colony (ABC), Dragonfly Algorithm (DA), Grey Wolf Optimizer (GWO), Cuckoo Search (CS), Composite Grey Wolf Optimizer (CGWO), and the standalone PSO and GWO methods. …”
Get full text

Cryptanalysis of hyperchaotic S-box generation and image encryption by Mohammad Mazyad Hazzazi, Gulraiz, Rashad Ali, Muhammad Kamran Jamil, Sameer Abdullah Nooh, Fahad Alblehai

Get full text

Cathepsin G, a Neutrophil Protease, Induces Compact Cell-Cell Adhesion in MCF-7 Human Breast Cancer Cells by Tomoya Kudo, Hideaki Kigoshi, Takashi Hagiwara, Takahisa Takino, Masatoshi Yamazaki, Satoru Yui

“…Cathepsin G subsequently induced cell condensation, a very compact cell colony, resulting due to the increased strength of E-cadherin-mediated cell-cell adhesion. …”
Get full text

Asparagine endopeptidase regulates lysosome homeostasis via modulating endomembrane phosphoinositide composition by Linli Yao, GuangHui Zi, Miao He, Yuhong Xu, Lulu Wang, Baowei Peng

“…Loss of AEP impaired colony formation by breast cancer cells in vitro and suppressed lung metastasis in mice. …”
Get full text

NOP2/Sun RNA Methyltransferase 4 Regulates the Mammalian Target of Rapamycin Signaling Pathway to Promote Hepatocellular Carcinoma Progression by Congren Wang, Shaoying Ke, Shaoze Lin, Conglin Lin, Zhibing Cai, Lingju Hong, Qunxiong Pan

“…Cell counting kit-8 and colony formation assays were employed to measure cell proliferation ability. …”
Get full text

Effects of Adding Clove (Syzygium aromaticum L.)  Seed Extract on Oxidative Stability, Microbial Activity, and Sensory Attributes in Beef Patties During Refrigerated Storage by Bestoon Hassan Ahmed, Naska Abdulqadir Mohammed Mohammed

“…Microbial growth was inhibited in a concentration-dependent manner; for instance, aerobic plate counts decreased from 5.31 to 4.68 Log10 colony forming unit (CFU)/g, and coliform counts declined from 2.92 to 2.57 Log10 CFU/g at 0.30% CSE. …”
Get full text

KLF5 promotes esophageal squamous cell carcinoma radioresistance by targeting the Keap1-Nrf2 pathway by Yang Wang, Yue-ying Yang, Abulajiang Kamili, Dilimulati Aishanjiang, Yi Liu

“…The effects of overexpression or downregulation of KLF5 on anti-irradiated cells' proliferation, migration, invasion, and apoptotic activity were studied through colony formation assay, Transwell assay, and flow cytometry. …”
Get full text

A study on beneficial impact of the use of medium-molecular-weight hydroxyethyl starch in granulocyte apheresis using continuous-flow cell separator Spectra Optia: A retrospective... by Amardeep Pathak, Devasis Panda, Narender Tejwani, Anurag Mehta

“…All the donors in both the groups received single 600 μg of granulocyte colony-stimulating factor subcutaneous injection followed by 8 mg of dexamethasone tablet 10–12 h and omnacortil 60 mg orally 3 h before harvest. …”
Get full text

Isolation and Characterization of Potential Antibiotic-Producing Actinomycetes from Water and Soil Sediments of Different Regions of Nepal by Bhanu Shrestha, Dharmendra Kumar Nath, Alina Maharjan, Anju Poudel, Roshani Nhuchhen Pradhan, Sagar Aryal

“…Different isolates were characterized by observing colony characteristics and microscopic characteristics. …”
Get full text

Neuroprotective Effects of Collagen-Glycosaminoglycan Matrix Implantation following Surgical Brain Injury by Jia-Hui Chen, Wei-Cherng Hsu, Kuo-Feng Huang, Chih-Huang Hung

“…Proinflammatory (tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells)) and anti-inflammatory (IL-10 and granulocyte-macrophage colony-stimulating factor (GMCSF)) cytokine expression was evaluated by enzyme-linked immunosorbent assays. …”
Get full text

Fluconazole-Pyridoxine Bis-Triazolium Compounds with Potent Activity against Pathogenic Bacteria and Fungi Including Their Biofilm-Embedded Forms by Marsel R. Garipov, Roman S. Pavelyev, Svetlana A. Lisovskaya, Elena V. Nikitina, Airat R. Kayumov, Alina E. Sabirova, Oksana V. Bondar, Albina G. Malanyeva, Alexander M. Aimaletdinov, Alfia G. Iksanova, Konstantin V. Balakin, Yurii G. Shtyrlin

“…While no biofilm structure destruction occurred, all compounds were able to diffuse into the matrix and reduce the number of colony-forming units by three orders of magnitude at 16 × MBC. …”
Get full text

Fermentation characteristics of lactofermented cucumbers using an isolated Lactiplantibacillus plantarum NCHU–FC1 strain by Hsuan-Min Wang, Shwu-Jene Tsai, Jin-Yuarn Lin

“…The pH value was quickly lower than 4.6 (aka high-acid foods), while total nitrite contents were below the standard limit using 1 × 107 colony forming unit (CFU)/mL Lpb. plantarum NCHU–FC1 at 4 °C for 5 days. …”
Get full text

Trusted fuzzy routing scheme in flying ad-hoc network by Sahabul Alam, Joydeep Kundu, Shivnath Ghosh, Arindam Dey

“…Second, the flying nodes' highly dynamic mobility pattern in 3D space may cause link disconnection because of their potential dispersion. Using ant colony optimization, it employs trusted leader drone selection within the cluster and safe routing among leaders. a fuzzy‐based UAV behavior analytics is presented for trust management in FANETs. …”
Get full text