Physical activity and the outcome of cognitive trajectory: a machine learning approach by Bettina Barisch-Fritz, Jay Shah, Jelena Krafft, Yonas E. Geda, Teresa Wu, Alexander Woll, Janina Krell-Roesch

“…Less is known about the value of ML for predicting cognitive decline in people with dementia (PwD). The aim of this study was to use an ML approach to identify variables associated with a multimodal PA intervention that may impact cognitive changes in PwD, i.e., by distinguishing between cognitive decliners and non-decliners. …”
Get full text

Cognitive Impairment in Genetic Parkinson’s Disease by A. Planas-Ballvé, D. Vilas

“…Monogenic forms of genetic PD show distinct cognitive profiles and rate of cognitive decline progression. Cognitive impairment is higher in GBA- and SNCA-associated PD, lower in Parkin- and PINK1-PD, and possibly milder in LRRK2-PD. …”
Get full text

Longitudinal study of care needs and behavioural changes in people living with dementia using in-home assessment data by Chloe Walsh, Alexander Capstick, Nan Fletcher-Lloyd, Jessica True, CR&T Group, Ramin Nilforooshan, Payam Barnaghi

“…Behavioural changes correlate with cognitive decline, functional impairment, caregiver distress, and care availability. …”
Get full text

Level of cognitive functioning among elderly patients in urban area of Bangladesh: A cross-sectional study. by Joynal Abedin Imran, Pradip Kumar Saha, Marzana Afrooj Ria, Syeda Saika Sarwar, Jannatul Ferdous Konok

“…Bangladesh is experiencing rapid urbanization and a growing elderly population, particularly in urban areas. Cognitive decline, ranging from mild cognitive impairment to dementia, is a prevalent issue among elderly populations globally. …”
Get full text

Nonconvulsive Status Epilepticus on Electroencephalography: An Atypical Presentation of Subacute Sclerosing Panencephalitis in Two Children by Pratibha Singhi, Arushi Gahlot Saini, Jitendra Kumar Sahu

“…Subacute sclerosing panencephalitis is a neurodegenerative disease secondary to measles infection that usually has a typical presentation with progressive myoclonia, cognitive decline, and periodic slow-wave complexes on electroencephalography. …”
Get full text

Dietary Fatty Acids and Predementia Syndromes by Vincenzo Solfrizzi, Vincenza Frisardi, Cristiano Capurso, Alessia D' Introno, Anna M. Colacicco, Gianluigi Vendemiale, Antonio Capurso, Francesco Panza

“…An increasing body of epidemiological evidence suggests that elevated saturated fatty acids (SFA) could have negative effects on age-related cognitive decline (ARCD). Furthermore, a reduction of risk for cognitive decline and mild cognitive impairment (MCI) has been found in population samples with elevated fish consumption, and high intake of monounsaturated fatty acids (MUFA) and polyunsaturated fatty acids (PUFA), particularly n-3 PUFA. …”
Get full text

Effect of Combined Antihypertensive and Lipid-Lowering Therapies on Cognitive Function: A New Treatment Strategy? by Ze-Min Kuang

“…Risk factors for cardiovascular disease such as hypertension and hyperlipidemia are associated with cognitive decline. However, there is still no clear evidence that the use of antihypertensive or lipid-lowering therapy can prevent or delay cognitive decline or development of dementia. …”
Get full text

Protection of Alzheimer’s disease progression by a human-origin probiotics cocktail by Santosh Kumar Prajapati, Shaohua Wang, Sidharth P Mishra, Shalini Jain, Hariom Yadav

“…In conclusion, our results suggest that this unique probiotics cocktail could serve as a prophylactic agent to reduce the progression of cognitive decline and AD pathology. This is achieved by beneficially modulating the microbiome, improving intestinal tight junction proteins, reducing permeability in both gut and BBB, and decreasing inflammation in the gut, blood circulation, and brain, ultimately mitigating AD pathology and cognitive decline.…”
Get full text

A measure of modifiable lifestyle factors shaping subjective cognitive reserve in the general population by Carmen Moret-Tatay, Carmen Moret-Tatay, José María Tormos Muñoz, José María Tormos Muñoz, Alvaro Pascual-Leone, Alvaro Pascual-Leone

“…Furthermore, discriminant validity was demonstrated by a significant negative correlation between SCR scores and subjective cognitive decline, suggesting that individuals with higher cognitive reserve experience lower levels of perceived cognitive decline. …”
Get full text

Advanced Asymptomatic Carotid Disease and Cognitive Impairment: An Understated Link? by Irena Martinić-Popović, Arijana Lovrenčić-Huzjan, Vida Demarin

“…Advanced carotid disease is known to be associated with symptomatic cerebrovascular diseases, such as stroke or transient ischemic attack (TIA), as well as with poststroke cognitive impairment. However, cognitive decline often occurs in patients with advanced carotid stenosis without clinically evident stroke or TIA, so it is also suspected to be an independent risk factor for dementia. …”
Get full text

Successful Aging and Longevity in Older Old Women: The Role of Depression and Cognition by Daniel Paulson, Mary Elizabeth Bowen, Peter A. Lichtenberg

“…Based in successful aging theory and terminal cognitive drop research, this paper investigates cerebrovascular burden (CVB), depressive symptoms, and cognitive decline as threats to longevity. A subsample of stroke-free women over the age of 80 was identified in the Health and Retirement Survey (years 2000–2008). …”
Get full text

Remembering what did not happen: the role of hypnosis in memory recall and false memories formation by Donato Giuseppe Leo, Donato Giuseppe Leo, Davide Bruno, Riccardo Proietti, Riccardo Proietti

“…Additionally, cardiovascular diseases may lead to cognitive decline and memory loss, also increasing the occurrence of false events recall. …”
Get full text

Iron induces blood-brain barrier alteration contributing to cognitive impairment in β-thalassaemia mice by Parinda Jamrus, Nuttanan Pholngam, Benjaporn Kiatpakdee, Kittikun Viwatpinyo, Jim Vadolas, Sukonthar Ngampramuan, Saovaros Svasti, Pornthip Chaichompoo

“…However, persistent iron overload may lead to chronic neuroinflammation, neurodegeneration, and cognitive decline. These results underscore the critical role of iron overload in accelerating cognitive decline in β-thalassaemia and suggest that regular monitoring of iron levels and chelation therapy may help prevent early cognitive impairment, ultimately improving the quality of life for β-thalassaemia patients.…”
Get full text

Relationship between Urinary Alzheimer-Associated Neuronal Thread Protein and Apolipoprotein Epsilon 4 Allele in the Cognitively Normal Population by Yuxia Li, Meimei Kang, Can Sheng, Guanqun Chen, Taoran Li, Jun Wang, Yanning Cai, Rong Wang, Ying Han

“…We investigated the relationship between urinary Alzheimer-associated neuronal thread protein (AD7c-NTP) levels and apolipoprotein epsilon 4 (ApoE ɛ4) alleles, as well as other factors that cause cognitive decline, in the cognitively normal population. …”
Get full text

The Effect of Physical Activity on Alzheimer’s Disease - Systematic Review by Julia Lachowska, Karolina Senior, Jerzy Smandek, Maja Mielczarek, Paulina Sroczyńska, Jan Sroczyński

“…Both RET and aerobic exercise have been shown to delay the onset of cognitive decline, with RET also reducing amyloid plaque formation and promoting neuroprotection. …”
Get full text

Relationships between muscle strength, lung function, and cognitive function in Chinese middle-aged and older adults: A study based on the China health and retirement longitudinal... by Yixuan Ma, Xinze Wu, Yinjiao Zhao, Weihao Hong, Yisheng Luan, Peiyu Song, Bing Zhang

“…Objective: As the population ages, concerns about cognitive decline have become increasingly relevant in medical consultations. …”
Get full text

Prolonged nightly fasting in older adults with memory decline: A single-group pilot study exploring changes in cognitive function and cardiometabolic risk factors by Dara L. James, Linda K. Larkey, Molly Maxfield, SeungYong Han, Edward Ofori, Alex E. Mohr, Nanako A. Hawley, Kate Alperin, Erica Ahlich, David E. Vance, Dorothy D. Sears

“… Abstract Introduction: Older age significantly increases risk for cognitive decline. A growing number of older adults (≥ 65 years) experience cognitive decline that compromises immediate and/or long-term health. …”
Get full text

The intricate interplay between dietary habits and cognitive function: insights from the gut-brain axis by Ruyi Zhang, Ruyi Zhang, Meiya Zhang, Pengyu Wang

“…The Mediterranean diet has been associated with improved cognitive performance and a delay in cognitive decline in elderly populations. However, challenges in dietary intervention implementation, including adherence and individual variability, remain. …”
Get full text

Revealing the Role of Social Support on Cognitive Deficits in Fibromyalgia Syndrome by Carmen M. Galvez-Sánchez, Gustavo A. Reyes del Paso, Casandra I. Montoro

“…Despite the relevance of cognitive deficits in fibromyalgia syndrome (FMS) and the attempts to elucidate the influence of the disorder symptoms in the cognitive decline reported by patients, no studies have explored the specific role of social support on cognition in FMS. …”
Get full text

Mapping and modeling age-related changes in intrinsic neural timescales by Kaichao Wu, Leonardo L. Gollo

“…Aging, often associated with cognitive decline, involves progressive neuronal and synaptic loss, reshaping brain structure and dynamics. …”
Get full text