Spatial analysis of socioeconomic data and its relationship with illicit crops in Nariño-Colombia. by Andrés Fernando Grajales-Marín, Fabio Humberto Sepúlveda-Murillo, Alex Tapia, Alexander Tabares

“…Concurrently, Nariño registers the highest levels of coca cultivation in Colombia, accounting for 65% of national cocaine production, reflecting the region's precarious conditions. …”
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A Unique Case of Cardiac Arrest following K2 Abuse by Saif Ibrahim, Farah Al-Saffar, Thomas Wannenburg

“…The causative association of sudden death with cocaine, methadone, and volatile agents is well established (Adgey et al. (1995) and Isner et al. (1986)). …”
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Successful Use of Ertapenem for the Treatment of Enterobacter cloacae Complex Infection of the Central Nervous System (CNS) by Sunish Shah, Dayna McManus, Jeffrey E. Topal

“…A 55-year-old female with a past medical history of cocaine use and hypertension was admitted for intracranial hemorrhage requiring right decompressive craniotomy with duraplasty. …”
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Prevalence of dual diagnosis in the south of Peru: descriptive clinical study by Jonathan A. Zegarra-Valdivia, Brenda Nadia Chino Vilca, Ernesto Cazorla Perez

“…Alcohol was the most used substance, followed by cannabis marijuana and cocaine base (PBC). The socio-family and individual vulnerability of the population is evidence for protection or resistance to mental illness, as well as the lack of implementation of effective policies in mental health care for dual disorders, showing worse prognosis and indexes every time higher.…”
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Current Controversies in the Prediction, Diagnosis, and Management of Cerebral Vasospasm: Where Do We Stand? by Young Lee, Scott L. Zuckerman, J. Mocco

“…Evidence regarding the effect of age, smoking, and cocaine use on the incidence and outcome of vasospasm is reviewed. …”
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Exploring the impact of xenobiotic drugs on forensic entomology for accurate post-mortem interval estimation by Sapna Jain, Jonathan J. Parrott, Gulnaz T. Javan

“…This systematic overview delves into the influence of drugs such as Morphine, heroin, Opiates, and cocaine on the variables affecting the use of forensically significant insects as evidence tools. …”
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Historical Pathways for Opioid Addiction, Withdrawal with Traditional and Alternative Treatment Options with Ketamine, Cannabinoids, and Noribogaine: A Narrative Review by Amber N. Edinoff, Natalie W. Wu, Catherine A. Nix, Bryce Bonin, Rama Mouhaffel, Stephen Vining, William Gibson, Elyse M. Cornett, Kevin S. Murnane, Adam M. Kaye, Alan D. Kaye

“…Of particular interest to the subject at hand, ketamine is promising in treating individuals addicted to opioids, alcohol, and cocaine. Therapeutically administered cannabinoids have been proposed for the treatment of multiple illnesses. …”
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Exploring the Novel Continuum-Cancellation Leal-Method for the Approximate Solution of Nonlinear Differential Equations by Hector Vazquez-Leal

“…Furthermore, we present the application of CCLM in several examples: Thomas–Fermi singular equation for the neutral atom, magnetohydrodynamic flow of blood in a porous channel singular boundary-valued problem, and a system of initial condition differential equations to model the dynamics of cocaine consumption in Spain. We present a computational convergence study for the proposed approximations resulting in a tendency of the RMS error to zero as the approximation order increases for all case studies. …”
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Impact of Methamphetamine Abuse: A Rare Case of Rapid Cerebral Aneurysm Growth with Review of Literature by James Fowler, Brian Fiani, Syed A. Quadri, Vladimir Cortez, Mudassir Frooqui, Atif Zafar, Fahad Shabbir Ahmed, Asad Ikram, Anirudh Ramachandran, Javed Siddiqi

“…Illicitly abused neurostimulants like cocaine and meth predispose patients to the aneurysmal formation with reported rupture at a younger age and in much smaller sized aneurysms. …”
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Evaluation of a Smoking Cessation Program for HIV Infected Individuals in an Urban HIV Clinic: Challenges and Lessons Learned by Debra Chew, Michael B. Steinberg, Polly Thomas, Shobha Swaminathan, Sally L. Hodder

“…Mean six-month abstinence rate amongst SCP participants was 16%. A history of cocaine or heroin use was predictive of continued smoking (odds ratio [OR] adjusted 0.20, 95% confidence interval [CI] 0.07–0.55) while smokers in the preparation stage of change were more likely abstinent at six months (OR adjusted 8.26, 95% CI 1.02–66.67). …”
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An Unusual Case of Anti-GBM Antibody Elevation in HIV-Associated Nephropathy by Vinay Minocha, Raafat Makary, Andreea Poenariu

“…We present a case of a 27-year-old African American female with a history of schizophrenia, cocaine abuse, and HIV infection who upon admission to our hospital was found to have severe acute kidney injury requiring hemodialysis. …”
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Paradoxical and Retrograde Air Embolism from Pressurized Peripheral Bolus by Joshua Santucci, Naresh Mullaguri, Anusha Battineni, Raviteja R. Guddeti, Christopher R. Newey

“…Her medical history was significant for intravenous heroin and cocaine abuse, methicillin-sensitive Staphylococcus aureus tricuspid valve infective endocarditis on vancomycin, patent foramen ovale, septic pulmonary embolism with cavitation, tracheostomy with chronic ventilator dependence, multifocal cerebral infarction, hepatitis C, nephrolithiasis, anxiety, and depression. …”
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Clinical Features and Long-Term Outcomes in Very Young Patients with Myocardial Infarction with Non-Obstructive Coronary Arteries by Pablo Juan-Salvadores, Víctor Alfonso Jiménez Díaz, Ana Rodríguez González de Araujo, Cristina Iglesia Carreño, Alba Guitián González, Cesar Veiga Garcia, José Antonio Baz Alonso, Francisco Caamaño Isorna, Andrés Iñiguez Romo

“…The incidence of major adverse cardiovascular events (MACE) at follow-up was significantly higher in the MINOCA (HR 4.13 (95%CI 1.22–13.89) and obstructive CAD (HR 4.59 (95%CI 1.90–10.99) patients compared to controls. Cocaine use HR 14.58 (95%CI 3.08–69.02), family history of CAD HR 6.20 (95%CI 1.40–27.43), and depression HR 5.16 (95%CI 1.06–25.24) were associated with a poor outcome in the MINOCA population. …”
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Xylazine as a Drug of Abuse and Its Effects on the Generation of Reactive Species and DNA Damage on Human Umbilical Vein Endothelial Cells by Luz Silva-Torres, Christian Veléz, Lyvia Álvarez, Beatriz Zayas

“…Our previous work demonstrated that XYL and its combination with cocaine (COC) and/or 6-monoacetylmorphine (6-MAM) induce cell death through an apoptotic mechanism. …”
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Transcriptomic Profile Analysis of Brain Tissue in the Absence of Functional TRPM8 Calcium Channel by Erick B. Saldes, Alexandra Erdmier, Jai Velpula, Timothy E. Koeltzow, Michael X. Zhu, Swapna Asuthkar

“…Among them, the androgen–estrogen receptor (AR-ER) pathway, steroidogenesis pathway, sexual reward pathway, and cocaine reward pathway are particularly worth noting. …”
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A cohort-based assessment of drug use trends during the COVID-19 pandemic: relationship with mood and sociodemographic factors in Brazil by Nubia Heidrich, Nubia Heidrich, Maurício Schüler Nin, Felipe Borges Almeida, Felipe Borges Almeida, Hilda M. R. M. Constant, Luana Freese, Helena M. T. Barros, Helena M. T. Barros

“…The ASSIST (alcohol, cannabis, hallucinogens, and cocaine/crack) and DASS-21 (anxiety, depression, and stress) scores decreased over time. …”
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Varying circumstances surrounding opioid toxicity deaths across ethno-racial groups in Ontario, Canada: a population-based descriptive cross-sectional study by Tara Gomes, Mina Tadrous, Sophie A Kitchen, Frank Crichlow, Tonya J Campbell, Cynthia Damba, Colin H Johnson, Ashley Smoke

“…Black people (median age: 35 years; SD: 0.40) and Asian people (median age: 37 years; SD: 0.30) generally died younger than white people (median age: 40 years), and there was greater male predominance in deaths among Asian people (86.2%; SD: 0.30), Latin American people (83.0%; SD: 0.21) and black people (80.3%; SD: 0.14) relative to white people (74.6%). Cocaine contributed to more deaths among black people (55.9%; SD: 0.37) and Asian people (45.1%; SD: 0.15) compared with white people (37.6%). …”
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A synthetic cyclic peptide for promoting antigen presentation and immune activation by Jiahui Zhang, Harrison Y. R. Madge, Asmaa Mahmoud, Lantian Lu, Wanyi Wang, Wenbin Huang, Prashamsa Koirala, Jazmina L. Gonzalez Cruz, Wei Yang Kong, Sahra Bashiri, Ahmed O. Shalash, Waleed M. Hussein, Zeinab G. Khalil, James W. Wells, Istvan Toth, Rachel J. Stephenson

“…., bovine serum albumin [BSA], receptor binding domain (RBD) of the SARS-CoV-2 protein responsible for COVID-19 infection [SARS-CoV-2 RBD]) and small molecular haptens (e.g., cocaine). All vaccine candidates self-assembled into sub-500 nm nanoparticles and induced high antigen-specific systemic IgG titers and opsonic potential compared to the antigen co-administered with a commercial adjuvant, complete Freund’s adjuvant. …”
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Effects of Glycyrrhizin (GL) Supplementation on Survival, Growth Performance, Expression of Feeding-Related Genes, Activities of Digestive Enzymes, Antioxidant Capacity, and Expres... by Yuntao Wang, Wenxuan Xu, Jianmin Zhang, Jiahui Liu, Zhen Wang, Yongtao Liu, Kangsen Mai, Qinghui Ai

“…Compared with the control, the mRNA expression of orexigenic factor genes including neuropeptide Y (npy) and agouti-related protein (agrp) were significantly increased in larvae fed the diet with 0.005% GL, while the mRNA expression of anorexigenic factor genes including thyrotropin-releasing hormone (trh), cocaine and amphetamine regulated transcript (cart), and leptin receptor (lepr) were significantly decreased in larvae fed the diet with 0.005% GL (P<0.05). …”
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Identification of Behavioral, Clinical, and Psychological Antecedents of Acute Stimulant Poisoning: Development and Implementation of a Mixed Methods Psychological Autopsy Study by Marley Antolin Muñiz, Vanessa M McMahan, Xochitl Luna Marti, Sarah Brennan, Sophia Tavasieff, Luke N Rodda, James Knoll, Phillip O Coffin

“…We selected deaths determined to be due to acute poisoning from cocaine or methamphetamine, which occurred 3‐12 months prior and were not attributed to suicide or homicide. …”
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