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3921
Cannabis consumption and risk of asthma: a systematic review and meta-analysis
Published 2025-01-01“…Future research should prioritize identifying moderating factors, such as the frequency and mode of cannabis consumption, to enhance understanding of this association and provide a stronger evidence base for potential public health interventions. Clinical trial number Not applicable.…”
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3922
Ewing sarcoma – pathomechanisms, standard treatment and new therapeutic perspectives
Published 2025-01-01“…Findings: The studies cited vary depending on the phase of the clinical trial they are on, of which teprotumumab, robatumumab, and a combination of cixutumumab/temsyrolimus, ivodesinib, Nivolumab (a PD-1 inhibitor), and Ipilimumab (a CTLA-4 inhibitor) are quite advanced as well as those conducted only on animals and in vitro like YK-4-279 molecule, mithramycin 2'-oxime, NK cells, siRNAs with cationic detonation nanodiamonds (DNDs) and Il-12 by means of lentiviruses. …”
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3923
LCZ696 Therapy Reduces Ventricular Tachyarrhythmia Inducibility in a Myocardial Infarction-Induced Heart Failure Rat Model
Published 2019-01-01“…LCZ696 (valsartan/sacubitril) therapy significantly reduced mortality in patients with heart failure (HF). Although a clinical trial (PARADISE-MI Trial) has been ongoing to examine the effects of LCZ696 in myocardial infarction (MI) patients, the effects of LCZ696 on remodeling of cardiac electrophysiology in animal models remain largely unclear. …”
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3924
Synergistic effects of PGPRs and fertilizer amendments on improving the yield and productivity of Canola (Brassica napus L.)
Published 2025-01-01“…Combining PGPRs with fertilizers for canola enhances nutrient efficiency, promotes sustainable growth, and boosts stress resilience, addressing agricultural and environmental challenges. Clinical trial number Not Applicable.…”
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3925
Prediction of post-contrast acute kidney injury by bedside ultrasonography
Published 2025-01-01“…Trial registration Clinical trial number: not applicable.…”
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3926
A non-randomised open-label exploratory ‘window of opportunity’ study of TG02 treatment in patients with locally advanced primary and recurrent RAS mutant colorectal cancer
Published 2025-01-01“…Background: TG02 is a peptide-based cancer vaccine eliciting immune responses to oncogenic codon 12/13 RAS mutations. This phase 1 clinical trial (NCT02933944) assessed the safety and immunological efficacy of TG02 adjuvanted by GM-CSF in patients with KRAS-mutant colorectal cancer. …”
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3927
High-dose dual therapy for Helicobacter pylori eradication inducing less impact on the gut microbiota
Published 2025-01-01“…Conclusions Compared to BQT, HDDT exerted less impact on the diversity and composition of the gut microbiota. Clinical trial registration ChiCTR2100053268.…”
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3928
Influence of strength and power training on the rate of force development, peak force and functional mobility in elderly people with Parkinson's disease: a randomized controlled tr...
Published 2025-01-01“…ObjectiveTo analyze the influence of lower limb muscle strength and muscle power training on rate of force development (RFD) and peak force (PF) in elderly people with Parkinson's disease (PD), as well as the effect of these training sessions influence on the functional mobility (FM) of this population.MethodsThis was a randomized controlled clinical trial and registered on the virtual platform for registration of experimental and non-experimental studies “Registro Brasileiro de Ensaios Clínicos (ReBEC)”. …”
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3929
Hymecromone Efficacy in the Treatment of Biliary Pancreatitis
Published 2019-12-01“…An open single-centre clinical trial included 30 patients with chronic pancreatitis (CP), which was diagnosed according to the Cambridge criteria. …”
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3930
Genome-wide identification and expression analysis of CBF/DREB1 gene family in Medicago sativa L. and functional verification of MsCBF9 affecting flowering time
Published 2025-01-01“…This study laid a foundation for further analysis of the function of the CBF family in alfalfa. Clinical trial number Not applicable.…”
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3931
Efficacy and safety of trabeculectomy versus peripheral iridectomy plus goniotomy in advanced primary angle-closure glaucoma: study protocol for a multicentre, non-inferiority, ran...
Published 2022-07-01“…Therefore, this multicentre, non-inferiority, randomised controlled clinical trial aims to compare the efficacy and safety of trabeculectomy versus peripheral iridectomy plus an ab interno goniotomy in advanced PACG with no or mild cataracts.Methods and analysis This non-inferiority, multicentre, randomised controlled trial will be conducted at seven ophthalmic departments and institutes across China. …”
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3932
Acupuncture treatment of restless legs syndrome: a randomized clinical controlled study protocol based on PET-CT and fMRI
Published 2024-12-01“…The results of this study will be published in peer-reviewed journals or presented at academic conferences.Clinical trial registrationhttps://www.chictr.org.cn/, identifier ChiCTR2000037287.…”
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3933
Youth experiencing homelessness at risk for suicide: psychosocial risk factors and service use patterns
Published 2025-02-01“…Methods A cross-sectional analysis of youth enrolled in a supportive housing randomized clinical trial. We categorized suicide risk into three groups (low-, moderate-, and high-risk) based on suicidal ideation and past-year suicide attempt. …”
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3934
Cost-effectiveness analysis of pembrolizumab plus chemotherapy versus chemotherapy in untreated advanced pleural mesothelioma in the Chinese healthcare system
Published 2025-01-01“…The purpose of this study was to assess its cost-effectiveness.Materials and methodsA Markov state-transition model was constructed using data from the IND227 phase 3 randomized clinical trial. Utility values for health states were taken from the IND227 trial, and direct medical costs were from the pertinent literature and local pricing data. …”
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3935
Trimethylamine Oxidation into the Proatherogenic Trimethylamine N-Oxide Is Higher in Coronary Heart Disease Men: From the CORDIOPREV Study
Published 2025-01-01“…Materials and Methods: This study was carried out within the framework of the CORDIOPREV study (NCT00924937; June 19, 2009), a clinical trial which included 827 men and 175 women with CHD, with a non-CVD population of 375 individuals (270 men and 105 women) as a reference group. …”
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3936
Enhancing lung transplantation with ECMO: a comprehensive review of mechanisms, outcomes, and future considerations
Published 2024-12-01“…Sources included peer-reviewed journals and clinical trial results, with emphasis on articles captured recent advancements in ECMO technology and techniques. …”
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3937
Stem Cell Therapy: A Compassionate Use Program in Perianal Fistula
Published 2019-01-01“…Under controlled circumstances and approved by European and Spanish laws, a compassionate use program allows the use of stem cell therapy for patients with nonhealing diseases, mostly complex fistula-in-ano, who do not meet criteria to be included in a clinical trial. Candidates had previously undergone multiple surgical interventions that had failed. …”
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3938
The battle of question formats: a comparative study of retrieval practice using very short answer questions and multiple choice questions
Published 2024-12-01“…To optimize the use of VSAQs in retrieval practice, it seems important to improve initial retrieval success to maximize learning outcomes. Clinical trial number Not applicable.…”
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3939
Immune checkpoint inhibitor-induced diabetes mellitus: clinical characteristics and risk factors
Published 2025-01-01“…Blood glucose monitoring is needed in patients receiving ICI therapy.Clinical trial registrationhttps://www.chictr.org.cn, identifier ChiCTR2300075974.…”
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3940
The association between the dietary inflammatory index during pregnancy and risk of gestational diabetes: a prospective cohort study and a meta-analysis
Published 2025-02-01“…The results need to be confirmed by larger cohort studies. Clinical trial number Not applicable.…”
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