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A synthetic chronogenetic gene circuit for programmed circadian drug delivery
Published 2025-02-01“…Once implanted in vivo, the constructs expressed circadian rhythms and entrained to daily light cycles, producing daily increases in biologic drug at the peak of Per2 expression. …”
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122
Selecting Energy-Efficient LED Retrofits with Optimal Color Qualities for New and Refurbished Buildings
Published 2024-12-01“…We demonstrate that energy efficiency and the color preference criteria for retrofitted LEDs must be considered and balanced with the potential impact on circadian rhythms as assessed by the melanopic daylight efficacy ratio. …”
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123
Nicotinamide mononucleotide boosts the development of bovine oocyte by enhancing mitochondrial function and reducing chromosome lagging
Published 2025-01-01“…Abstract Nicotinamide adenine dinucleotide (NAD(H)) and its metabolites function as crucial regulators of physiological processes, allowing cells to adapt to environmental changes such as nutritional deficiencies, genotoxic factors, disruptions in circadian rhythms, infections, inflammation, and exogenous substances. …”
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124
Nocturnal Light Pollution Synergistically Impairs Glucose Metabolism With Age and Weight in Monkeys
Published 2024-01-01“…It is widely accepted that glucose metabolism can be impaired by circadian rhythms and sleep disturbances. Concurrently, exposures to light at night have been closely linked to circadian and sleep disturbances. …”
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125
Sleep Deprivation Influences Circadian Gene Expression in the Lateral Habenula
Published 2016-01-01“…Clock genes play an important role in the generation and maintenance of circadian rhythms but are also involved in regulating sleep homeostasis. …”
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126
RETRACTED ARTICLE: Serum melatonin levels and in a sample of Iranian patients with migraine
Published 2024-10-01“…The production of melatonin in the pineal gland, which is crucial for controlling circadian rhythms and sleep–wake cycles, is altered in various conditions, including neurological disorders such as migraine. …”
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127
Comparing Circadian Dynamics in Primary Derived Stem Cells from Different Sources of Human Adult Tissue
Published 2017-01-01“…There is evidence to suggest that circadian rhythms and daily circadian temporal cues have substantial effects on stem cell activation, cell cycle, and differentiation. …”
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128
The finding and researching algorithm for potentially oscillating enzymatic systems
Published 2021-06-01“…Oscillatory processes are responsible for cell cycles in both prokaryotes and eukaryotes, for circadian rhythms, for synchronous coupling of respiration with cardiac contractions, etc. …”
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129
Genetics of aging and longevity
Published 2016-09-01“…Genes and signaling pathways that regulate stress response, metabolism, growth of cells and organism, maintaining of genome and proteome integrity, qualitative and quantitative mitochondria composition, inflammatory response, apoptosis and selection of viable cells, as well as circadian rhythms were considered. The redistribution of energy resources from one pathway to the other can induce or inhibit the ”longevity program”, providing increased vitality and aging slowdown. …”
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130
Signaling pathway mechanisms of circadian clock gene Bmal1 regulating bone and cartilage metabolism: a review
Published 2025-01-01“…We hope to provide new insights for the prevention and treatment of bone/cartilage diseases related to circadian rhythms.…”
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131
Circadian Clock Gene Bmal1: A Molecular Bridge from AKI to CKD
Published 2025-01-01“…Kidney function is influenced by circadian rhythms, with the circadian gene Bmal1 being vital in managing these cycles. …”
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132
Influence of time-of-day on neuromuscular performance in team sport athletes: a systematic review and meta-analysis
Published 2025-01-01“…IntroductionAlthough circadian rhythms have been shown to influence some neuromuscular performance tasks, the time-of-day effect on team sports performance athletes remains equivocal. …”
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133
PATIENTS' CHRONOTYPE INFLUENCE IN TREATMENT EFFICIENCY OF PLACENTA CRYERXTRACT CHANGES IN MAXILLOFACIAL PHLEGMONS
Published 2024-04-01“…The dependence of lipid peroxidation markers on the timing of surgical intervention on the patient's circadian rhythm was established, which is most clearly observed in the 2nd clinical group. …”
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134
Development and validation of a protocol to determine product perception in relation to the moment of the day
Published 2025-06-01“…To address this gap, we developed and validated a method to measure sensory perception and examine its variations throughout the day in alignment with circadian rhythms. Fifty-two university students completed the Munich Chronotype Questionnaire and, over four days within a week, they participated in sensory evaluations using a web-based questionnaire. …”
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135
Circadian Variation of Zinc, Copper, Selenium, and Bromine in Human Milk
Published 2025-01-01“…The ‘V’ shaped pattern generally disappeared in the fourth, fifth, and sixth months. Conclusion: Circadian rhythms for zinc, copper, selenium, and bromine varied during the first six months postpartum. …”
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136
Candidate genes for productivity identified by genome-wide association study with indicators of class in the Russian meat merino sheep breed
Published 2020-12-01“…The listed genes encode proteins involved in the control of the cell cycle and DNA replication, regulation of cell proliferation and apoptosis, lipid and carbohydrate metabolism, the development of the inflammatory process and the work of circadian rhythms. Thus, the candidate genes under consideration can influence the formation of exterior features and productive qualities of sheep. …”
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137
Transcriptomic Analysis of Wheat Under Multi LED Light Conditions
Published 2024-12-01“…Additionally, this study revealed differential effects of blue and red light on the expression levels of genes related to hormones such as cytokinin (CK) and salicylic acid (SA) synthesis as well as significant changes in pathways such as flavonoid biosynthesis, circadian rhythms, chlorophyll synthesis, and flowering. …”
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138
Bright night sleeping environment induces diabetes and impaired glucose tolerance in non-human primates
Published 2025-02-01“…It is widely accepted that glucose metabolism can be impaired by circadian rhythms disruption and sleep disturbances, both closely linked to exposure to light at night. …”
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139
Two-Dimensional Transition Metal Dichalcogenide: Synthesis, Characterization, and Application in Candlelight OLED
Published 2024-12-01“…Low-color-temperature candlelight organic light-emitting diodes (OLEDs) offer a healthier lighting alternative by minimizing blue light exposure, which is known to disrupt circadian rhythms, suppress melatonin, and potentially harm the retina with prolonged use. …”
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140
Association between instillation time of glaucoma eye drops and their efficacy
Published 2020-06-01“…An interesting and promising area of modern pharmacotherapy is chronotherapy that implies target prescription of a drug in specific daytime considering circadian rhythms to achieve maximum effect. This paper reviews current modalities of personalized chronopharmacotherapy and their potential application in r outine glaucoma practice. …”
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