Mechanism of Transcranial Magnetic Stimulation in the Treatment of Neuropathic Pain by SUN Yu-jia, ZHANG Jun-feng, YAN Long, FAN Shi-yu, QIAN Yu-lin, CONG Shan, YU Tao

“…Neuropathic pain （NP） is a persistent and refractory chronic pain condition resulting from damage or disease within the somatosensory nervous system. …”
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How Do We Treat Children with Anterior Cutaneous Nerve Entrapment Syndrome and Is the Biopsychosocial Model Also Being Applied? A Scoping Review by Anke P. C. Top, Thomas G. de Leeuw, Wichor M. Bramer, Bernadette C. M. de Mol, Frank J. P. M. Huygen, Maaike Dirckx

“…In accordance with the World Health Organization (WHO) guidelines for managing chronic pain in children, these patients and their families and caregivers should be treated within the context of the biopsychosocial model; pain should not be treated purely as a biomedical problem. …”
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Sacral Fracture Nonunion Treated by Bone Grafting through a Posterior Approach by Sang Yang Lee, Takahiro Niikura, Yoshitada Sakai, Masahiko Miwa, Kotaro Nishida, Ryosuke Kuroda, Masahiro Kurosaka

“…Nonunion of a sacral fracture is a rare but serious clinical condition which can cause severe chronic pain, discomfort while sitting, and significant restriction of the level of activities. …”
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A safety and feasibility randomized placebo controlled trial exploring electroencephalographic effective connectivity neurofeedback treatment for fibromyalgia by Lucy Anderson, Dirk De Ridder, Paul Glue, Ramakrishnan Mani, Cindy van Sleeuwen, Mark Smith, Divya Bharatkumar Adhia

“…Abstract Fibromyalgia is a chronic pain condition contributing to significant disability worldwide. …”
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A scoping review of randomized trials assessing the impact of n-of-1 trials on clinical outcomes. by Joyce P Samuel, Susan H Wootton, Travis Holder, Donald Molony

“…<h4>Findings</h4>Twelve randomized trials of the n-of-1 approach were identified in conditions spanning chronic pain, osteoarthritis, chronic irreversible airflow limitation, attention-deficit hyperactivity disorder, hyperlipidemia, atrial fibrillation, statin intolerance, and hypertension. …”
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Oral administration of hydrolyzed collagen alleviates pain and enhances functionality in knee osteoarthritis: Results from a randomized, double-blind, placebo-controlled study by Juan Antonio Carrillo-Norte, Guillermo Gervasini-Rodríguez, María Ángeles Santiago-Triviño, Virginio García-López, Rafael Guerrero-Bonmatty

“…Osteoarthritis (OA) is a major source of chronic pain and disability, representing a significant global health concern that affects 10–15 % of individuals aged over 60, with a higher prevalence among females than males. …”
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Neurovascularization inhibiting dual responsive hydrogel for alleviating the progression of osteoarthritis by Wenpin Qin, Zhangyu Ma, Guo Bai, Wen Qin, Ling Li, Dongxiao Hao, Yuzhu Wang, Jianfei Yan, Xiaoxiao Han, Wen Niu, Lina Niu, Kai Jiao

“…In an in vivo OA model, intraarticular injection of OSPPB accelerates the healing process of condyles and alleviates chronic pain by inhibiting neurovascularization at the osteochondral interface. …”
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Serum interleukin-6, interleukin-8, and interleukin-1 receptor antagonist levels in South Indian fibromyalgia patients and its correlation with disease severity by Sandeep Surendran, C B Mithun, Vishnu S Chandran, Suma Balan, Arun Tiwari

“…Background: Fibromyalgia is a chronic pain syndrome characterized by widespread diffuse pain and multiple tender points along with sleep disturbances, fatigue, and psychological distress. …”
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Pain and the perception of space in fibromyalgia by Michele Scandola, Maddalena Beccherle, Enrico Polati, Giorgia Pietroni, Elena Rossato, Vittorio Schweiger, Valentina Moro

“…The results of the studies investigating the impact of pain on distance estimation remain inconclusive. 28 women suffering from chronic pain and fibromyalgia (FM), and 24 healthy women (HC) were assessed for musculoskeletal, neuropathic, and visceral pain by means of the Widespread Pain Index, the Symptom Severity Scale and an ad-hoc devised questionnaire for pain (the Verona Pain Questionnaire). …”
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The Effect of Electroacupuncture on PKMzeta in the ACC in Regulating Anxiety-Like Behaviors in Rats Experiencing Chronic Inflammatory Pain by Junying Du, Junfan Fang, Cun Wen, Xiaomei Shao, Yi Liang, Jianqiao Fang

“…Electroacupuncture (EA) has effects on chronic pain and pain-related anxiety. Protein kinase Mzeta (PKMzeta) has been proposed to be essential for the maintenance of pain and may interact with GluR1 to maintain CNS plasticity in the anterior cingulate cortex (ACC). …”
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Detection of Cannabinoid Receptor Expression by Endometriotic Lesions in Women with Endometriosis as an Alternative to Opioid-Based Pain Medication by Sarah Allam, Elizabeth Paris, Itzel Lazcano, Pincas Bitterman, Sanjib Basu, James O’Donnell, Animesh Barua

“…Endometriosis is a disease of women of reproductive age associated with infertility and reproductive failure as well as chronic pain of varying degrees depending on the stage of the disease. …”
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The prevalence of hypermobile Ehlers–Danlos syndrome at a gender-affirming primary care clinic by Theo Stein, Shannon Collins, Joshua St. Louis

“…Within the sample of patients with hypermobile Ehlers–Danlos syndrome, 81.4% were found to have diagnoses of anxiety, depression, or attention deficit hyperactivity disorder, 50.8% had a history of migraines or dysautonomia, 39.0% had a history of gastroesophageal reflux disease, irritable bowel syndrome, nausea, diarrhea, or gastroparesis, 16.9% had history of mast cell activation disorder, 32.2% had postural orthostatic tachycardia syndrome, 30.5% had dysmenorrhea, 83.1% reported chronic pain, and 44.1% reported chronic fatigue. Conclusions: We found that 2.7% of the 2180 patients had a diagnosis of hypermobile Ehlers–Danlos syndrome syndrome. …”
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DNA Methylation May be Involved in the Analgesic Effect of Hyperbaric Oxygen via Regulating FUNDC1 by Kun Liu, Hao Wu, Rui Gao, Guang Han

“…Neuropathic pain (NP) is a type of chronic pain which lacks predictable, effective, and safe therapeutic options. …”
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Examining the effects of race/ethnicity and other factors on outcomes of care for complex regional pain syndrome type 1 in the United States. by Anh Khoa Vo, James A G Crispo, Lisa J W Liu, Dylan Thibault, Allison W Willis, Donald E G Griesdale, John L K Kramer, Jacquelyn J Cragg

“…Complex regional pain syndrome is a chronic pain disorder marked by symptoms such as swelling, impaired motor function, and sympathetic dysfunction. …”
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The Effect of Baduanjin Qigong on Impact of Disease and Sleep Quality in Elderly Fibromyalgia Patients by Heiresh Saeed Ali, Razieh Khanmohammadi, Elahe Arabameri, Ina Shaw, Brandon Shaw

“…Introduction: Fibromyalgia is marked by widespread chronic pain, fatigue, and disrupted sleep, significantly impacting quality of life. …”
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Copper and iron as unique trace elements linked to fibromyalgia risk by Wenxing Zeng, Minhua Hu, Luyao Ma, Feng Huang, Ziwei Jiang

“…Abstract Fibromyalgia (FM) is a prevalent chronic pain condition with a complex and not fully understood etiology. …”
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Repetitive transcranial magnetic stimulation as a modality of treatment in patients with fibromyalgia by Rawan M. El Shahat, Mona A. El Sebaie, Sahar F. Ahmed, Shereen I. Fawaz, Marwa A. Kamel, Marwa A. Nassef

“…Repetitive transcranial magnetic stimulation (rTMS) is an emerging nonpharmacological therapeutic option for fibromyalgia. rTMS involves an electromagnetic coil placed on the scalp that is rapidly turned on and off to generate short magnetic pulses to the brain (2). rTMS can reduce chronic pain by triggering inhibitory neural pathways at the level of the dorsal horn of the spinal cord. …”
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Longitudinal Relationship between the Introduction of Medicinal Cannabis and Polypharmacy: An Australian Real-World Evidence Study by Maja Kalaba, Graham M. L. Eglit, Matthew T. Feldner, Patrizia D. Washer, Tracie Ernenwein, Alistair W. Vickery, Mark A. Ware

“…Recent studies recommend medicinal cannabis (MC) as a potential treatment for chronic pain (CP) when conventional therapies are not successful; however, data from Australia is limited. …”
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Treatment of Brachial Plexus Injuries following Gunshot Injuries: A Systematic Review by Rohun Gupta, Isabel Herzog, Lauren Phung, Jacquelyn Roth, Joseph Weisberger, Margaret Luthringer, Edward S. Lee, Ashley Ignatiuk

“…Brachial plexus injuries (BPI) from gunshot injuries are uncommon but usually severe and can cause chronic pain, loss of function, and permanent nerve damage. …”
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An In Vitro and In Vivo Comparison of Osteogenic Differentiation of Human Mesenchymal Stromal/Stem Cells by Jamie Mollentze, Chrisna Durandt, Michael S. Pepper

“…Clinically acceptable protocols could be developed in which MSCs are used to aid in bone regeneration providing relief for patients with chronic pain. The aim of this review is to examine the differences between studies conducted in vitro and in vivo with regard to the osteogenic process to better define the gaps in current osteogenic research. …”
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