The Role of Controlled Breathing in Pain Management by Maria Wydro, Magdalena Grotowska, Martyna Łukasiewicz, Aleksandra Strawińska

“…Additionally, the combination of DSB and vagus nerve stimulation (VNS) has shown promise in managing chronic pain and improving musculoskeletal pain thresholds. …”
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Cohort profile: the Halland osteoarthritis (HALLOA) cohort–from knee pain to osteoarthritis: a longitudinal observational study in Sweden by Ann Bremander, Maria L E Andersson, S Bergman, Katarina Aili, Emma Haglund

“…It is also important to study the development of chronic pain in OA, to get tools to identify individuals at risk and to be able to offer them treatment.Trial registration number ClinicalTrials.gov (NCT04928170).…”
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Plasticity-Related PKMζ Signaling in the Insular Cortex Is Involved in the Modulation of Neuropathic Pain after Nerve Injury by Jeongsoo Han, Minjee Kwon, Myeounghoon Cha, Motomasa Tanioka, Seong-Karp Hong, Sun Joon Bai, Bae Hwan Lee

“…According to recent reports, neural plasticity in the brain including the IC can be induced by nerve injury and may contribute to chronic pain. Continuous active kinase, protein kinase Mζ (PKMζ), has been known to maintain the long-term potentiation. …”
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Antinociceptive and Anti-Inflammatory Activities of Teucrium persicum Boiss. Extract in Mice by Abdolhossein Miri, Javad Sharifi-Rad, Kaveh Tabrizian, Ali Akbar Nasiri

“…Oral gavaged of TPE revealed significant analgesic effect on chronic pain in both formalin test and sciatic nerve ligated animals. …”
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A Novel Nitronyl Nitroxide with Salicylic Acid Framework Attenuates Pain Hypersensitivity and Ectopic Neuronal Discharges in Radicular Low Back Pain by Wen-Juan Han, Lei Chen, Hai-Bo Wang, Xiang-Zeng Liu, San-Jue Hu, Xiao-Li Sun, Ceng Luo

“…Evidence has accumulated that reactive oxygen species and inflammation play crucial roles in the development of chronic pain, including radicular low back pain. Nonsteroid anti-inflammatory drugs (NSAIDs), for example, salicylic acid, aspirin, provided analgesic effects in various types of pain. …”
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Stem Cells from Human Exfoliated Deciduous Teeth Attenuate Trigeminal Neuralgia in Rats by Xiaofeng Bai, Xuedi Zhang, Chun Wang, Yao Liu, Xuemei Liu, Yu Fan, Xia Zhang

“…Therefore, these results provide preclinical evidence that supports the use of SHED in the treatment of trigeminal neuralgia and potentially other chronic pain conditions.…”
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Exploring the Associations between Sleep Problems and Chronic Musculoskeletal Pain in Adolescents: A Prospective Cohort Study by Lee Harrison, Sue Wilson, Marcus R Munafò

“…BACKGROUND: The prevalence of musculoskeletal chronic pain in adolescents is estimated to be approximately 4% to 40%. …”
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Preclinical Science Regarding Cannabinoids as Analgesics: An Overview by ME Lynch

“…Since then, potent antinociceptive and antihyperalgesic effects of cannabinoid agonists in animal models of acute and chronic pain; the presence of cannabinoid receptors in pain-processing areas of the brain, spinal cord and periphery; and evidence supporting endogenous modulation of pain systems by cannabinoids has provided support that cannabinoids exhibit significant potential as analgesics. …”
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Protocol for the impact of CBT for insomnia on pain symptoms and central sensitisation in fibromyalgia: a randomised controlled trial by Michael Robinson, Chokkalingam Siva, Christina S McCrae, Ashley F Curtis, Jason Craggs, Chelsea Deroche, Pradeep Sahota, Roland Staud

“…Previous research suggests sustained hyperarousal mediated by a neural central sensitisation mechanism may underlie insomnia and chronic pain symptoms in fibromyalgia. We hypothesise CBT-I will improve insomnia symptoms, improve clinical pain and reduce central sensitisation. …”
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Reliability and concurrent validity of the iHandy level mobile application to measure thoracolumbar range of motion in low back pain patients by Nimra Ijaz, Saima Riaz, Tahreem Raza, Sidra Ali

“…Conclusions iHandy level smartphone applications might be considered reliable and valid for assessing thoracolumbar motion ranges in individuals with chronic pain in the lower back.…”
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Use of behavioural activation to manage pain: a systematic scoping review by G Lorimer Moseley, Marianne Gillam, Martin Jones, Sandra Walsh, Richard John Gray, Trevor Barker, Tesfahun Eshetie, Kate M. Gunn, Kham Tran

“…High-quality research is required to test if BA is an effective intervention for chronic pain.…”
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Neural Mobilization Treatment Decreases Glial Cells and Brain-Derived Neurotrophic Factor Expression in the Central Nervous System in Rats with Neuropathic Pain Induced by CCI in R... by Aline Carolina Giardini, Fabio Martinez dos Santos, Joyce Teixeira da Silva, Mara Evany de Oliveira, Daniel Oliveira Martins, Marucia Chacur

“…Glial cells are implicated in the development of chronic pain and brain-derived neurotropic factor (BDNF) released from activated microglia contributes to the nociceptive transmission. …”
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The impact of comorbid depression in chronic rhinosinusitis on post-operative sino-nasal quality of life and pain following endoscopic sinus surgery by Javier Ospina, Guiping Liu, Trafford Crump, Jason M. Sutherland, Arif Janjua

“…Abstract Background Depression and chronic pain are debilitating disorders that co-exist with many chronic diseases. …”
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Novel Techniques to Manage Temporomandibular Disorders – A Multidisciplinary Approach by Mehul A. Shah, Kunal Shankarrao Deshmukh, Kabir Suman Dash, Shafali Agrawal, Ankita Mishra, Vignesh Kamath

“…Current literature supports the interrelationship between chronic pain and behavioral, psychological, and psychosocial factors. …”
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Cannabinoids for the Treatment of Pain: An Update on Recent Clinical Trials by Mark Ware, Pierre Beaulieu

“…The present article summarizes recent clinical trial data in the field of pain management and suggests that the potential for cannabinoid therapy for chronic pain states is encouraging. Clinicians working in pain management should be aware of the options becoming available from the cannabinoid class of medications.…”
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Intra-Articular Application of Sluijter-Teixera Poisson Pulsed Radiofrequency in Symptomatic Patients with Knee Osteoarthritis: Focus upon Clinical Efficacy and Safety by D. Filippiadis, A. Tsochatzis, E. Petsatodis, S. Galanis, G. Velonakis, C. Giankoulof, A. Kelekis

“…To retrospectively evaluate the effectiveness of intra-articular application of Sluijter-Teixera Poisson pulsed radiofrequency (STP PRF) in knee osteoarthritis symptomatic patients with chronic pain refractory to conservative therapies. Materials and Methods. …”
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Effects of a Pain Catastrophizing Induction on Sensory Testing in Women with Chronic Low Back Pain: A Pilot Study by Chloe J. Taub, John A. Sturgeon, Kevin A. Johnson, Sean C. Mackey, Beth D. Darnall

“…Pain catastrophizing, a pattern of negative cognitive-emotional responses to actual or anticipated pain, maintains chronic pain and undermines response to treatments. Currently, precisely how pain catastrophizing influences pain processing is not well understood. …”
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Knowledge translation initiatives at the Transitional Pain Service: insights from healthcare provider outreach and patient education by Anna M. Lomanowska, Rabia Tahir, Christina Choo, Sabrina Zhu, Dora Y. Wang, P. Maxwell Slepian, Joel Katz, Hance Clarke

“…Abstract Evidence-based treatment of chronic pain requires a multidisciplinary approach grounded in the biopsychosocial model. …”
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A Need for Further Education on Buprenorphine in Pain Medicine by Jamal Hasoon, Anvinh Nguyen, Ivan Urits, Christopher Robinson, Omar Viswanath, Alan D Kaye

“…With the ongoing opioid epidemic in the United States there has been a strong transition towards utilizing multi-modal analgesia, interventional procedures, and non-opioid medications when managing acute and chronic pain. There has also been an increased interest in utilizing buprenorphine. …”
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The Implications of Mental Health and Trauma in Interstitial Cystitis by Tyler R. Bendrick, Graison L. Sitenga, Cameron Booth, Matthew P. Sacco, Christine Erie, Danyon J. Anderson, Alan D. Kaye, Ivan Urits

“…This review also revealed an apparent lack of, and need for, trauma informed care and screening for PTSD in patients diagnosed with IC or other chronic pain syndromes.…”
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