The Muscadine Grape (Vitis rotundifolia Michx) by Peter C. Andersen, Ali Sarkhosh, Dustin Huff, Jacque Breman

“…Euvitis and Muscadania have somatic chromosome numbers of 38 and 40, respectively. Vines do best in deep, fertile soils, and they can often be found in beside river beds.  …”
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Fluorescence In Situ Hybridization (FISH) Signal Analysis Using Automated Generated Projection Images by Xingwei Wang, Xiaodong Chen, Yuhua Li, Hong Liu, Shibo Li, Roy R. Zhang, Bin Zheng

“…In this study, a dual-detector fluorescence image scanning system was applied to scan four specimen slides with FISH-probed chromosome X. A CAD scheme was developed to detect analyzable interphase cells and map the multiple imaging slices recorded FISH-probed signals into the 2-D projection images. …”
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Development of Genome-Wide Unique Indel Markers for a Heat-Sensitive Genotype in Wheat (<i>Triticum aestivum</i> L.) by Huijie Zhai, Kunpeng Xu, Meng Wang, Zhenchuang Wang, Ziyang Cai, Ao Li, Anxin He, Xiaoming Xie, Lingling Chai, Mingjiu Liu, Xingqi Ou, Zhongfu Ni

“…A chromosome segment substituted line (CSSL) represents an ideal resource for studying quantitative traits like thermotolerance. …”
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Response to Infliximab in Crohn’s Disease: Genetic Analysis Supporting Expression Profile by Luz María Medrano, Carlos Taxonera, Cristina González-Artacho, Virginia Pascual, María Gómez-García, Manuel Barreiro-de Acosta, José L. Pérez-Calle, Fernando Bermejo, Antonio López-Sanromán, Dolores Martín Arranz, Javier P. Gisbert, Juan Luis Mendoza, Javier Martín, Concepción Núñez, Elena Urcelay

“…A tagging strategy was used to select genetic polymorphisms that cover the variability present in the chromosomal regions encoding the identified genes with altered expression. …”
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Role of Bone Marrow-Derived Stem Cells in Polyps Development in Mice with ApcMin/+ Mutation by Michele Barone, Maria Principia Scavo, Raffaele Licinio, Michele Piombino, Nicola De Tullio, Rosanna Mallamaci, Alfredo Di Leo

“…At 4 and 7 weeks after transplantation, BM-derived colonocytes were recognized by colocalization of Y-chromosome and Cdx2 protein (specific colonocyte marker). …”
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Factor-Reduced Human Induced Pluripotent Stem Cells Efficiently Differentiate into Neurons Independent of the Number of Reprogramming Factors by Andreas Hermann, Jeong Beom Kim, Sumitra Srimasorn, Holm Zaehres, Peter Reinhardt, Hans R. Schöler, Alexander Storch

“…In an attempt to minimize the risk of chromosomal disruption and to simplify reprogramming, several studies demonstrated that a reduced set of reprogramming factors is sufficient to generate iPSC. …”
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Selective JAK2 pathway inhibition enhances anti-leukemic functionality in CD19 CAR-T cells by Kohei Mitsuno, Masaya Suematsu, Yuki Naito, Azusa Mayumi, Hideki Yoshida, Shinya Osone, Toshihiko Imamura, Yozo Nakazawa, Shigeki Yagyu, Tomoko Iehara

“…While CD19-targeted CAR-T cells and Janus kinase (JAK) inhibitors have independently shown efficacy against certain B-cell leukemias, such as Philadelphia chromosome-like acute lymphoblastic leukemia, the concurrent use of JAK1/2 inhibitors, such as ruxolitinib, has been implicated in reducing CAR-T cell potency by inhibiting the JAK1-dependent T cell activation pathway. …”
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Identification of a distal enhancer of Ucp1 essential for thermogenesis and mitochondrial function in brown fat by Duo Su, Tingting Jiang, Yulong Song, Die Li, Siyuan Zhan, Tao Zhong, Jiazhong Guo, Li Li, Hongping Zhang, Linjie Wang

“…Here, we employed circularized chromosome conformation capture coupled with next-generation sequencing (4C-seq) to generate high-resolution chromatin interaction profiles of Ucp1 in interscapular brown adipose tissue (iBAT) and epididymal white adipose tissue (eWAT) and revealed marked changes in Ucp1 chromatin interaction between iBAT and eWAT. …”
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Fine-mapping of PmHHM, a broad-spectrum allele from a wheat landrace conferring both seedling and adult resistance to powdery mildew by Bisheng Fu, Bisheng Fu, Bisheng Fu, Zhixin Lin, Lijuan Yan, Qiaofeng Zhang, Caiyun Liu, Caiyun Liu, Jin Cai, Jin Cai, Wei Guo, Wei Guo, Ying Liu, Wenling Zhai, Shuangjun Gong, Feng Xu, Jizhong Wu, Jizhong Wu, Jizhong Wu

“…It was then fine-mapped to an interval with a genetic distance of 0.0031 cM and a physical distance of 187.4 kb on chromosome 4AL of the Chinese Spring reference sequence v.2.1. …”
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Pleura-Based Lipomatous Neoplasm with RUNX1T1::PLAG1 Rearrangement and RB1 Gene Deletion by Rayan Sibira, Anna Vu, Ryan Martinez, Emilian Racila, Siddhartha Sen, Diana Oramas

“…The genetic hallmark involves clonal rearrangements of the chromosomal region 8q11 > q13 (8q12). The oncogene PLAG1 (pleomorphic adenoma gene 1) is situated on band 8q12. …”
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Enhancement of Growth, Antioxidant Activity, and Immunity in Nile Tilapia (<i>Oreochromis niloticus</i>) Through Recombinant <i>Bacillus subtilis</i> Expressing L-Gulonolactone Oxi... by Jirawadee Kaewda, Surintorn Boonanuntanasarn, Papungkorn Sangsawad, Pimpisut Manassila, Chatsirin Nakharuthai

“…To enhance antioxidant properties and vitamin C-related effects, we employed recombinant technology to integrate the <i>GULO</i>-encoding gene into the <i>Bacillus subtilis</i> chromosome. In this study, fish were divided into four groups: those fed with a basal diet (CON), a basal diet + vitamin C (VC), a basal diet + wild-type <i>B. subtilis</i> (BS), and a basal diet + recombinant <i>B. subtilis</i> (BS+GULO). …”
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Development of a 50K SNP array for whole-genome analysis and its application in the genetic localization of eggplant (Solanum melongena L.) fruit shape by Chuying Yu, Qihong Yang, Weiliu Li, Yaqin Jiang, Guiyun Gan, Liangyu Cai, Xinchun Li, Zhiqiang Li, Wenjia Li, Min Zou, Yang Yang, Yikui Wang

“…The BSA-seq data were located in the 78444173−84449348 interval on chromosome 3, with a size of 6 Mb, which was narrowed to 712.6 kb through fine mapping. …”
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Detection of inversion with breakpoints in ARSB causing MPS VI by whole-genome sequencing: lessons learned and best practices by Yufeng Huang, Wenyue Deng, Hui Huang, Xiankai Zhang, Xiaohong Chen, Jian Ye, Sukun Luo, Ting Yu, Hui Yao, Hao Du, Xuelian He

“…By performing WGS, we found a paracentric inversion involving chromosome 5q14.1q13.2 (78180730-138771424 inv), disrupting the ARSB gene on the proband and his father. …”
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Polymorphisms in immunosuppression-related genes are associated with AML by Mingying Li, Mingying Li, Jingjing Ye, Jingjing Ye, Mengyuan Chang, Mengyuan Chang, Lei Feng, Lei Feng, Tingting Liu, Tingting Liu, Di Zhang, Di Zhang, Yuyan Wu, Yuyan Wu, Yuechan Ma, Yuechan Ma, Guangqiang Meng, Guangqiang Meng, Chunyan Ji, Chunyan Ji, Tao Sun, Tao Sun

“…We then analyzed the relationship between these SNPs and AML susceptibility, treatment response, and prognosis.ResultsOur findings indicated that rs4883263 in the CD163 gene is a protective factor for AML susceptibility and chromosomal karyotype abnormalities. Additionally, rs4883263 in CD163 was related to low PLT count at diagnosis, while rs2272022 in CD200 was protective against low PLT count. rs4780335 in CIITA was associated with high WBC count at diagnosis and worse OS. …”
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Human Leukocyte Antigen Class I and II Alleles and Overall Survival in Diffuse Large B-Cell Lymphoma and Follicular Lymphoma by Yani Lu, Amr M. Abdou, James R. Cerhan, Lindsay M. Morton, Richard K. Severson, Scott Davis, Wendy Cozen, Nathaniel Rothman, Leslie Bernstein, Stephen Chanock, Patricia Hartge, Sophia S. Wang

“…Genetic variation in the 6p21 chromosomal region, including human leukocyte antigen (HLA) genes and tumor necrosis factor (TNF), has been linked to both etiology and clinical outcomes of lymphomas. …”
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Role of Anti-MICA Antibodies in Graft Survival of Renal Transplant Recipients of India by Mohit Chowdhry, R. N. Makroo, Mandhata Singh, Manoj Kumar, Yogita Thakur, Vandana Sharma

“…The MIC (MHC class I chain-related) genes are a group of nonclassical MHC genes, located in the MHC class 1 region of chromosome 6. The aim of the present study was to find the prevalence of MHC class 1 chain-related (MICA) alloantibodies in patients undergoing live-related donor renal transplantation and its role in short-term graft survival. …”
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Analysis of fetal fraction in non-invasive prenatal testing with low-depth whole genome sequencing by Xiaolei Xie, Weiguo Yin, Fuguang Li, Suxia Xuan, Yu Ouyang

“…There was no statistically significant difference in the ratio of chromosome 13, 18, and 21 between pregnant and non-pregnant women. …”
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DNA Quality Assessment for Array CGH by Isothermal Whole Genome Amplification by Tineke E. Buffart, Marianne Tijssen, Thijs Krugers, Beatriz Carvalho, Serge J. Smeets, Ruud H. Brakenhoff, Heike Grabsch, Gerrit A. Meijer, Henry B. Sadowski, Bauke Ylstra

“…DNAs before and after amplification yielded the same segmentation patterns of chromosomal copy number changes for both the fresh DNA sample and the FFPE samples. …”
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Identification of the AHP family reveals their critical response to cytokinin regulation during adventitious root formation in apple rootstock by Ke Li, Ke Li, Ke Li, Huan Li, Wei Ling Liang, Jing Ju Liu, Hui Yue Tian, Li Hu Wang, Li Hu Wang, Yan Hong Wei, Yan Hong Wei

“…The 13 MdAHPs family members were named MdAHP1 to MdAHP13 by chromosome positions. The physicochemical properties, phylogenetic relationship, motifs, and elements of their proteins were also analyzed. …”
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Retrospective Analysis of Pregnancy Terminations: 9-Years Experience at a Tertiary Hospital in Southeastern Turkey by Neslihan Bayramoglu Tepe, Reyhan Gunduz, Omer Faruk Dizibuyuk, Huseyin Caglayan Ozcan, Ozge Komurcu Karuserci, Seyhun Sucu, Tanyeli Guneyligil Kazaz, Ali Irfan Kutlar

“…Anomalies that led to termination were grouped as central nervous system , cardiovascular system, gastrointestinal system, genitourinary system, pulmonary, musculoskeletal, head-neck, chromosomal, genetic, multiple anomalies and others. …”
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