Senescent cell depletion alleviates obesity-related metabolic and cardiac disorders by Tábatha de Oliveira Silva, Guilherme Lunardon, Caroline A. Lino, Amanda de Almeida Silva, Shiju Zhang, Maria Cláudia Costa Irigoyen, Yao Wei Lu, John D. Mably, Maria Luiza M. Barreto-Chaves, Da-Zhi Wang, Gabriela P. Diniz

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Distribution of sasX, mupA, and qacA/B genes and determination of genetic relatedness of epidemic methicillin-resistant Staphylococcus aureus strains associated with bloodstream in... by Rui Zhao, Bingyu Du, Lingling Hu, Chenxi Li, Fen Xue, Xing Wang, Changhong Jiang, Jinghua Wang, Yanfeng Zhao

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Rapid identification and phenotyping of nonalcoholic fatty liver disease patients using a machine‐based approach in diverse healthcare systems by Anna O. Basile, Anurag Verma, Leigh Anne Tang, Marina Serper, Andrew Scanga, Ava Farrell, Brittney Destin, Rotonya M. Carr, Anuli Anyanwu‐Ofili, Gunaretnam Rajagopal, Abraham Krikhely, Marc Bessler, Muredach P. Reilly, Marylyn D. Ritchie, Nicholas P. Tatonetti, Julia Wattacheril

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Dose-response associations of device-measured sleep regularity and duration with incident dementia in 82391 UK adults by Wenxin Bian, Raaj K. Biswas, Matthew N. Ahmadi, Yu Sun Bin, Svetlana Postnova, Andrew J. K. Phillips, Nicholas A. Koemel, Jean-Philippe Chaput, Shantha M. W. Rajaratnam, Peter A. Cistulli, Emmanuel Stamatakis

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Laparoscopic excision of deep rectovaginal endometriosis in BSGE endometriosis centres: a multicentre prospective cohort study by Paul Smith, Lucky Saraswat, Sanjay Vyas, Thomas Ind, Ertan Saridogan, Elizabeth Ball, Edward Morris, James Clark, Tony Chalhoub, David Rowlands, Moiad Alazzam, Dominic Byrne, Tamara Curnow, Alfred Cutner, T Justin Clark, Iris Menninger, Yousri Afifi, Kevin Phillips, Saikat Banerjee, Robert Richardson, Jeremy Hawe, Barry Whitlow, Emmanuel Ofuasia, Ashwini Trehan, Tyrone Carpenter, Christian Becker, Stuart Jack, Kumar Kunde, Chris Barnick, Alan Farthing, Graham Phillips, John Bidmead, Mohamed Abdel-aty, George Botros, Marlin Mubarak, Christian Kremer, Stanley Okolo, Edmond Edi-osagi, Kamel Shehata-iskander, Gaity Ahmad, Jonathan Frappell, Brice Rodriguez, Yemi Coker, Gourab Misra, Adam Moors, Chris Guyer, Caroline Overton, Suku George, Oliver Chappatte, Richard Penketh, Funlayo Odejinmi, Keith Louden, Jon Hughes

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Testing a Web-Based Interactive Comic Tool to Decrease Obesity Risk Among Racial and Ethnic Minority Preadolescents: Randomized Controlled Trial by May May Leung, Katrina F Mateo, Marlo Dublin, Laura Harrison, Sandra Verdaguer, Katarzyna Wyka

“…The mean total usability score was high and moderately high for the experimental and comparison groups, respectively (mean 4.01, SD 0.37 and mean 3.81, SD 0.51; P=.048), based on a 5-point Likert scale). Children in both groups found the tool acceptable, and few reported difficulties logging in or accessing content. …”
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Classification of risk for transmission of vaccine-preventable diseases in Brazilian municipalities: comparative analysis before and after the national movement for vaccination and... by Ana Catarina de Melo Araújo, Thales Philipe Rodrigues da Silva, Janaina Fonseca Almeida Souza, Krishna Mara Rodrigues Freire, Fernanda Penido Matozinhos, Eder Gatti Fernandes

“…Methods This is an epidemiological, ecological study using secondary data on vaccination coverage, dropout rates, and homogeneity of vaccination coverage (HCV) for ten immunobiologicals recommended for children under 2 years of age. The study aims to compare the years 2022 and 2023 in Brazil. …”
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Artificial intelligence can help individualize Wilms tumor treatment by predicting tumor response to preoperative chemotherapy by Ahmed Nashat, Ahmed Alksas, Rasha T. Aboulelkheir, Ahmed Elmahdy, Sherry M. Khater, Hossam M. Balaha, Israa Sharaby, Mohamed Shehata, Mohammed Ghazal, Salama Abd El-Wadoud, Ayman El-Baz, Ahmed Mosbah, Ahmed Abdelhalim

“…Materials and Methods: A single-center database was reviewed for children <18 years diagnosed with WT and received PC between 2001 and 2021. …”
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Characterization of Listeria monocytogenes strains isolated from soil under organic carrot farming by Maciej Nowak, Zbigniew Paluszak, Natalia Wiktorczyk-Kapischke, Katarzyna Grudlewska-Buda, Anna Budzyńska, Joanna Skonieczna-Kurpiel, Ewa Wałecka-Zacharska, Monika Huse-Kutowska, Krzysztof Skowron

“…This is an important aspect in organic farming, where products are chosen as a healthier option and consumed by children and the elderly.MethodsThe isolates were subjected to genetic similarity assessment (PFGE method), and the tested strains were evaluated for antibiotic susceptibility (disc-diffusion method), invasiveness (HT-29 line human colon cancer cell line), coaggregation with Salmonella Enteritidis, biofilm-forming ability and the effect of disinfectants on the biofilm.ResultsTwenty-seven isolates of L. monocytogenes were isolated from 250 soil samples, 10 of which were genetically different. 80% of the tested strains were sensitive to the tested antibiotics. …”
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De Novo Mutation of m.3243A>G together with m.16093T>C Associated with Atypical Clinical Features in a Pedigree with MIDD Syndrome by Zhixin Jiang, Yinan Zhang, Jingbin Yan, Fengwen Li, Xinqian Geng, Huijuan Lu, Xiaoer Wei, Yanmei Feng, Congrong Wang, Weiping Jia

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The multidisciplinary approach to the treatment of paediatric chronic pain: a qualitative analysis through focus groups by Aldana Paola Ercolano, Sabrina Galvan, Tessa Louise Marchesan, Alessia Gavioli, Gerardo Papa, Mariarita Todaro, Lidia Berforini D’Aquino, Alessia Zanatta, Andrea Vianello

“…The World Health Organization (WHO) has recently promoted a multidisciplinary approach for pediatric chronic pain, integrating physical, psychological, and pharmacological interventions, given the high prevalence of pain in pediatric populations, affecting up to 46% of children and adolescents. However, recent studies highlight gaps in healthcare providers’ competencies in managing pediatric chronic pain, and the need to update professional training and explore further non-pharmacological approaches to improve its management. …”
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Use High-Flow Nasal Cannula for Acute Respiratory Failure Patients in the Emergency Department: A Meta-Analysis Study by Cheng-Chieh Huang, Hao-Min Lan, Chao-Jui Li, Tsung-Han Lee, Wen-Liang Chen, Wei-Yuan Lei, Pei-You Hsieh, Mei-Chueh Yang, Chu-Chung Chou, Han-Ping Wu, Yuan-Jhen Syue

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Intravesical BCG in patients with non-muscle invasive bladder cancer induces trained immunity and decreases respiratory infections by J Alfred Witjes, Alina Vrieling, Mihai G Netea, Leo A B Joosten, Katja K H Aben, Sita H Vermeulen, Joost L Boormans, Antoine G van der Heijden, Boris Novakovic, Jelmer H van Puffelen, Liesbeth van Emst, Denise Kooper, Tahlita C M Zuiverloon, Ursula T H Oldenhof, Tessel E Galesloot, Lambertus A L M Kiemeney, Egbert Oosterwijk

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Uncovering women's healthcare access challenges in low- and middle-income countries using mixed effects modelling approach: Insights for achieving the Sustainable Development Goals... by Bewuketu Terefe, Belayneh Shetie Workneh, Gebreeyesus Abera Zeleke, Enyew Getaneh Mekonen, Alebachew Ferede Zegeye, Agazhe Aemro, Berhan Tekeba, Tadesse Tarik Tamir, Mulugeta Wassie, Mohammed Seid Ali

“…On the other hand, factors such as divorce/widowhood, the number of young children, household size, female household heads, rural residence, and region have been linked to higher odds of facing healthcare access challenges. …”
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Multi-Center Outcome Analysis of 16 Face Transplantations – A Retrospective OPTN Study by Leonard Knoedler, Thomas Schaschinger, Tobias Niederegger, Gabriel Hundeshagen, Gabriel Hundeshagen, Adriana C. Panayi, Curtis L. Cetrulo, Maxime Jeljeli, Elena Hofmann, Max Heiland, Steffen Koerdt, Alexandre G. Lellouch, Alexandre G. Lellouch, Alexandre G. Lellouch

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Surgical resection, radiotherapy and percutaneous thermal ablation for treatment of stage 1 non-small cell lung cancer: protocol for a systematic review and network meta-analysis by Arun Chockalingam, Menelaos Konstantinidis, Brandon Koo, John Timothy Moon, Andrew Tran, Sahar Nourouzpour, Emily Lawson, Kathleen Fox, Peiman Habibollahi, Bruno Odisio, Mohammed Loya, Ali Bassir, Nariman Nezami

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Unravelling distinct patterns of metagenomic surveillance and respiratory microbiota between two P1 genotypes of Mycoplasma pneumoniae by Hailong You, Bin Yang, Huifang Liu, Wencai Wu, Fei Yu, Nan Lin, WenJiao Yang, Bingxue Hu, Yong Liu, Hongyan Zou, Sijia Hao, Yunping Xiao, Teng Xu, Yanfang Jiang

“…However, no significant differences were observed in the co-detection odds ratio between children and other age groups in P1-2. This study is the first to demonstrate differences in relative abundance, diversity of respiratory microbiota and co-detection rate of opportunistic pathogen between M. pneumoniae P1-1 and P1-2. …”
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Antenatal pelvic floor muscle exercise intervention led by midwives in England to reduce postnatal urinary incontinence: APPEAL feasibility and pilot randomised controlled cluster... by Karla Hemming, Jonathan Bishop, Sarah Dean, Jean Hay-Smith, Tim Coleman, Elizabeth Edwards, Christine MacArthur, Debra Bick, Mark Pearson, Rohini Terry, Eivor Oborn, Sara Webb, Eleni Gkini, Victoria Salmon, Ellie Jones, Helena Frawley

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Enriched environment rescues bisphenol A induced anxiety-like behavior and cognitive impairment by modulating synaptic plasticity by Jiong Li, Guangyin Yu, Laijian Wang, Wenjun Zhang, Wenya Ke, Yifei Li, Danlei Liu, Keman Xie, Yuanyuan Xu, Caihui Cha, Guoqing Guo, Jifeng Zhang

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The effect of zopiclone co-administration on sertraline initial dosage optimization in pediatric major depressive disorder patients based on model-informed precision dosing by Xiao Chen, Ke Hu, Hao-Zhe Shi, Su-Mei He, Yang Yang, Chao-Wen Yang, Yue Zhang, Xue Tian, Ye Li, Yu-Hang Gao, Wen-Yi Xu, Cun Zhang, Dong-Dong Wang

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