X-Linked Autism Type 9 Caused by a Hemizygote Pathogenic Variant in the TMLHE Gene: Etiological Diagnosis in an Adult Male with Moderate Intellectual Disability by Verhoeven WM, Pfundt R, Engelke UF, Kluijtmans LA, Egger JI

“…To prevent regressive autistic episodes in young children, it is highly recommended to consider next-generation sequencing techniques as the first step in the differential diagnostic process of autism.Keywords: epsilon-trimethyllysine hydroxylase gene, TMLHE, levocarnitine, autism, intellectual disability, contextual neuropsychology, psychopathology…”
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Epsin3 promotes non-small cell lung cancer progression via modulating EGFR stability by Huiling Su, Jie Shen, Chenzi Gao, Yue Zhao, Wanyu Deng, Bo Qin, Xin Zhang, Juan Lai, Qian Wang, Jie Dou, Min Guo

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From guideline to practice: three years of ICH S11 insights and recommendations by Diana Tavares, Hsiao-Tzu Chien, Hsiao-Tzu Chien, Maria Elzbieta Sheean, Peter Theunissen, Peter Theunissen, Peter van Meer, Peter van Meer, Peter van Meer, Karen Van Malderen

“…Juvenile Animal Studies (JAS) may be warranted to ensure the safe clinical use of medicines for children. The ICH S11 guideline was developed to guide the need for and design of JAS, and proposes a weight-of-evidence (WoE) approach. …”
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Impact of COVID-19 on paediatric admissions to a Chinese hospital: a single-centre retrospective chart review by Jie Zheng, Yan-hui Chen

“…Objective To explore the impact of the COVID-19 on the distribution, type and patterns of diseases in hospitalised children under local antiepidemic measures.Design Retrospective chart review.Setting Electronic medical records of patients hospitalised in the paediatric department of a tertiary hospital in South China from 21 January 2019 to 20 January 2021.Participants Records of 2139 patients.Outcome measures Data were analysed before and during the COVID-19 pandemic. …”
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Subjective and objective vestibular changes that occur following paediatric cochlear implantation: systematic review and meta-analysis by Michael Yong, Emily Young, Jane Lea, Hannah Foggin, Erica Zaia, Frederick K. Kozak, Brian D. Westerberg

“…Study selection Articles published from 1980 until the present which documented pre-operative and post-operative vestibular testing on children under the age of 18 were used. Data extraction Parameters that were assessed included number of patients, pre- and post-operative vestibular-evoked myogenic potentials (VEMPs), head impulse testing (HIT), calorics, and posturography, timing of pre- and post-operative testing, symptomatology, and other demographic data such as etiology of the hearing loss. …”
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Comprehensive Iranian guidelines for the diagnosis and management of maple syrup urine disease: an evidence- and consensus- based approach by Noushin Rostampour, Setila Dalili, Hossein Moravej, Zhila Afshar, Negar Yazdani, Seyedeh Tahereh Mousavi, Parastoo Rostami, Daniel Zamanfar, Maryam Yahay, Abdolhossein Nikravesh, Zahra Beyzaei, Mohamad Ahangar Davoodi, Atefeh Sedaghat, Tahora Hakemzadeh, Ali Talea

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Central obesity is a burden even in normal weight adolescents of a non-metropolitan Indian City: A case for alarm and action for prevention and control by Tabassum Nawab, Zulfia Khan, Iqbal M. Khan, Mohammad A. Ansari

“…Introduction: Central obesity (CO) leads to increased cardiovascular and metabolic risks in children and adolescents. The evidence on prevalence of central obesity and its correlates are lacking among adolescents in India. …”
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History of Pain Research and Management in Canada by Harold Merskey

“…Their work continues while a variety of basic and clinical studies are advancing knowledge of fundamental mechanisms, including work by Henry and by Sawynok on purines; by Salter and by Coderre on spinal cord mechanisms and plasticity; by Katz on postoperative pain; by several workers on children's pain; and by Bushnell and others in Montreal on cerebral imaging. …”
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Identifying Factors Associated with Barriers in the Number of Antenatal Care Service Visits among Pregnant Women in Rural Parts of Ethiopia by Sali Suleman Hassen, Belete Mulatu Teshale, Lema Abate Adulo

“…To fill this discrepancy, the concerned bodies including government and nongovernmental organizations should work on the identified factors in the rural parts of the country to save children and mothers.…”
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Safety, Immunogenicity, and Efficacy of Cytomegalovirus Vaccines: A Systematic Review of Randomized Controlled Trials by Manuela Chiavarini, Anita Genga, Giorgia Maria Ricciotti, Marcello Mario D’Errico, Pamela Barbadoro

“…<b>Background/Objectives:</b> Cytomegalovirus (CMV) is widespread and mostly causes asymptomatic infections in immunocompetent hosts, but it may lead to severe and life-threatening diseases in immunocompromised individuals, such as transplant patients and congenitally infected children, representing a significant public health concern. …”
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Postnatal cytomegalovirus infection and its effect on hearing and neurodevelopmental outcomes among infants aged 3-10 months: A cohort study in Eastern Uganda. by Noela Regina Akwi Okalany, David Mukunya, Peter Olupot-Olupot, Martin Chebet, Francis Okello, Andrew D Weeks, Fred Bisso, Thorkild Tylleskär, Kathy Burgoine, Ingunn Marie Stadskleiv Engebretsen

“…<h4>Background</h4>Hearing impairment and neurodevelopmental disorders pose a significant global health burden in children. The link between postnatal cytomegalovirus (CMV) infection and these outcomes remains unclear. …”
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The Role of Immersive Experience in Anxiety Reduction: Evidence from Virtual Reality Sessions by Dominika Wilczyńska, Tamara Walczak-Kozłowska, David Alarcón, María José Arenilla, Jose Carlos Jaenes, Marcelina Hejła, Mariusz Lipowski, Joanna Nestorowicz, Henryk Olszewski

“…We assessed immersion in VR using the Polish adaptation of the Immersion Questionnaire and anxiety using the Polish adaptations of the State–Trait Anxiety Inventory (STAI-X1) and its early adolescent version, the State–Trait Anxiety Inventory–Children (STAI-C1). Results and Conclusions: The results indicate that individuals using the new VR device demonstrated increased immersion and reduced post-test anxiety levels, highlighting the significance of immersion in enhancing positive affect, mitigating the negative effects of VR technology, and offering insights for future development and refinement of VR solutions.…”
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Diagnosis, treatment, and management of Mpox in urban Informal Settlements in Southwestern Nigeria: an ethnographic approach by Olufunke Adegoke, Megan Schmidt-Sane, Michael Kunnuji, Syed Abbas, Akanni Lawanson, Ayodele Jegede, Hayley MacGregor

“…We interviewed a total of 28 interlocutors who were either confirmed or suspected cases of Mpox or parents of children who are confirmed or suspected Mpox cases identified by the public health workers. …”
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Increased Body Mass Index during Therapy for Childhood Acute Lymphoblastic Leukemia: A Significant and Underestimated Complication by Helen C. Atkinson, Julie A. Marsh, Shoshana R. Rath, Rishi S. Kotecha, Hazel Gough, Mandy Taylor, Thomas Walwyn, Nicholas G. Gottardo, Catherine H. Cole, Catherine S. Choong

“…We undertook a retrospective review of children diagnosed with acute lymphoblastic leukemia (ALL) and treated with modern COG protocols (n=80) to determine longitudinal changes in body mass index (BMI) and the prevalence of obesity compared with a healthy reference population. …”
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THE ATTITUDE OF STUDENT YOUTH TO FAMILY VALUES (CASE STUDY OF THE SVERDLOVSK REGION) by Yu. R. Vishnevsky, M. V. Yachmeneva

“…The objective reason of these phenomena consists in the period of social and economic reforms dragged on over several decades; the spontaneous and unpredictable nature of those reforms have turned the prospects of the family institute to be uncertain and obliged people to strengthen their fears for the future and future of their children, which in turn resulted in complicated decision making on marriage by young people. …”
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Third Trimester Lower Extremity Lymphorrhea by Kaori Morimoto, Luke O’Rourke

“…We report a case of a 32-year-old multigravida patient pregnant with her third child and has two living full-term children (G3P2003). Her pregnancy was complicated by obesity, smoking (vape), and previous history of fetal growth restriction. …”
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What are the Thoughts of Women Whose Husbands&rsquo; Frozen Testicular Sperm Is Thawed for in vitro Fertilization on the Day of Oocyte Retrieval? A Qualitative Study by He Y, Wei Q, Chen X, Zhang C, Wang Z

“….; b. shared expectations for children help couples establish a common goal).Conclusion: It is recommended that healthcare practitioners implement strategies to enhance patient education and awareness surrounding assisted reproductive technology. …”
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Molecular Detection of Panton Valentine Leukocidin Toxin in Clinical Isolates of Staphylococcus aureus from Kiambu County, Kenya by Sani Iliya, Jonathan Mwangi, Ronald Maathai, Mary Muriuki, Christopher Wainaina

“…This study shows that PVL positive isolates occur in the sampled hospitals in the county and female as well as children must be taken into consideration among patients with wound infections when isolating S. aureus.…”
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Effects of Essential Oils as Antioxidant and Cryoprotective Agents in Improving Frozen and Thawed Human Sperm Criteria by Hamza Goujet, Ismail Kaarouch, Abderrahim Malki, Modou Mamoune Mbaye, Rosalie Cabry, Noureddine Louanjli, Taha Rhouda, Moncef Benkhalifa

“…Sperm cryopreservation provides patients undergoing oncological, surgical, or infertility treatments the opportunity to conceive their own children, using assisted reproductive technologies. …”
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Formulation and In Vitro Evaluation of Oral Capsules from Liquid Herbal Antimalarials Marketed in Ghana by Christina Osei-Asare, Fredrick William Akuffo Owusu, Philomena Entsie, Ama Kwansima Annan, Rita Akosua Gyamaa, Edem Makafui Amenuke

“…In Sub-Saharan and tropical regions of Africa, malaria continues to claim the life of one out of every twenty children below the age of five years. In adults, mortality rates are lower, but frequent debilitating attacks reduce the quality of life for chronic sufferers. …”
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