-
541
ITGAX promotes gastric cancer progression via epithelial-mesenchymal transition pathway
Published 2025-01-01“…Moreover, ITGAX enhanced cell proliferation, invasion, and tumorigenic capacity in mouse models. …”
Get full text
Article -
542
Anticancer effect of curcumin on breast cancer and stem cells
Published 2018-06-01“…Numerous studies have shown that curcumin, a natural compound, exerts anticancer effects by inhibiting cancer cell proliferation and metastasis and by inducing cell cycle arrest and apoptosis. …”
Get full text
Article -
543
Omentin-1 Ameliorated Free Fatty Acid-Induced Impairment in Proliferation, Migration, and Inflammatory States of HUVECs
Published 2020-01-01“…An FFA-induced endothelial cell injury model was established to investigate the role of omentin-1 in this process. Cell proliferation was analyzed with the Cell Counting Kit assay and flow cytometry. …”
Get full text
Article -
544
Identification of Common Oncogenic Genes and Pathways Both in Osteosarcoma and Ewing’s Sarcoma Using Bioinformatics Analysis
Published 2022-01-01“…Knockdown of FN1, COL1A1, and COL1A2 enhanced the cell proliferation and migration of U2OS under the restriction of cisplatin. …”
Get full text
Article -
545
Spontaneous Tumor Lysis Syndrome in a Patient with a Dedifferentiated Endometrial Adenocarcinoma
Published 2017-01-01“…TLS is observed mainly among tumors with rapid cell proliferation or high sensitivity to antineoplastic treatment. …”
Get full text
Article -
546
Fibrous Histiocytoma in the Far Lateral Frontal Sinus—A Rare Observation
Published 2024-12-01“…Histopathological examination of the excised tissue revealed characteristic features of benign fibrous histiocytoma, including spindle cell proliferation and the presence of histiocytes and siderophages. …”
Get full text
Article -
547
ZNF652-Induced circRHOT1 Promotes SMAD5 Expression to Modulate Tumorigenic Properties and Nature Killer Cell-Mediated Toxicity in Bladder Cancer via Targeting miR-3666
Published 2021-01-01“…The results from CCK-8, EDU, Transwell migration, and NK cell-mediated cytotoxicity detection assays suggested that circRHOT1 knockdown could markedly suppress BC cell proliferation and migration level and could aggravate the sensitivity of BC cells to NK cells. …”
Get full text
Article -
548
Role of T Regulatory Cells and Myeloid-Derived Suppressor Cells in COVID-19
Published 2022-01-01“…In viral infections, MDSC levels are highly increased, and they have the potential to suppress T cell proliferation and reduce viral clearance. Some subsets of MDSCs are expanded in the blood of COVID-19 patients; however, there is a controversy whether this expansion has pathogenic or protective effects in COVID-19 patients. …”
Get full text
Article -
549
Apoptosis, Inflammatory Bowel Disease and Carcinogenesis: Overview of International and Greek Experience
Published 2003-01-01“…A balance between cell proliferation (Ki-67 overexpression) and apoptosis (Bax protein overexpression) may partly explain the low incidence of cancer development in Greek inflammatory bowel disease patients.…”
Get full text
Article -
550
Regulation of adult-born and mature neurons in stress response and antidepressant action in the dentate gyrus of the hippocampus
Published 2025-02-01“…Regarding adult-born neurogenic processes in the DG, chronic stress, such as repeated social defeat, suppresses cell proliferation during and immediately after stress; however, this effect is transient. …”
Get full text
Article -
551
Quercetin inhibits the biological activity of endometrial cancer by regulating autophagy: A network pharmacology analysis and cellular experimental validation
Published 2025-02-01“…Cell Counting Kit-8 and flow cytometry assays were used to evaluate cell proliferation and apoptosis; cell invasive and migratory abilities were assessed by Transwell and wound healing assays, respectively; the observation of the cell ultrastructure was performed by transmission electron microscopy; the relative protein expressions were measured by the western blot assay. …”
Get full text
Article -
552
The Role of Neurokinin-1 Receptor in the Microenvironment of Inflammation and Cancer
Published 2012-01-01“…Recently, it has become apparent that SP can induce tumor cell proliferation, angiogenesis, and migration via the NK-1 receptor, and that the SP/NK-1 receptor complex is an integral part of the microenvironment of inflammation and cancer. …”
Get full text
Article -
553
Proteolytic Processing of CD44 and Its Implications in Cancer
Published 2021-01-01“…These include the protooncogene tyrosine-protein kinase Src (c-Src)/signal transducer and activator of transcription 3 (STAT3), the epithelial growth factor receptor, the estrogen receptor, Wnt/βcatenin, or Hippo signaling pathways all of which are associated to cell proliferation, differentiation, or cancer progression. …”
Get full text
Article -
554
MFAP5 inhibits the malignant progression of endometrial cancer cells in vitro
Published 2024-12-01“…HEC-1-A and Ishikawa cells overexpressing MFAP5 were created. Cell proliferation, apoptosis, migration, and invasion were evaluated using CCK8, colony formation, flow cytometry, and transwell assays. …”
Get full text
Article -
555
GrB-Fc-KS49, an anti-EMP2 granzyme B fusion protein therapeutic alters immune cell infiltration and suppresses breast cancer growth
Published 2024-12-01“…In vivo, the GrB-Fc-KS49 showed efficacy against a TNBC syngeneic (4T1/FLuc) mouse model, reducing tumor volume and cell proliferation and increasing cell death compared with controls. …”
Get full text
Article -
556
Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth
Published 2025-01-01“…The combination of bakuchiol and isobavachalcone synergistically inhibited cancer cell proliferation in vitro. Importantly, it also prevented tumor development in xenografted NOD/SCID mice. …”
Get full text
Article -
557
NCAPD3 promotes diffuse large B-cell lymphoma progression through modulating SIRT1 expression in an H3K9 monomethylation-dependent manner
Published 2025-02-01“…NCAPD3 deficiency impeded cell proliferation, induced apoptosis and increased the chemosensitivity. …”
Get full text
Article -
558
Myotubularin-Related Phosphatase 3 Promotes Growth of Colorectal Cancer Cells
Published 2014-01-01“…Knockdown of MTMR3 resulted in a significant reduction in cell proliferation in both HCT116 and SW1116 cells. Moreover, knockdown of MTMR3 led to S phase cell cycle arrest. …”
Get full text
Article -
559
Development and characterization of in vitro inducible immortalization of a murine microglia cell line for high throughput studies
Published 2025-01-01“…The addition of doxycycline facilitates rapid cell proliferation, allowing for population expansion. Upon withdrawal of doxycycline, this monoclonal microglial cell line differentiates, resembling in vivo microglial physiology as demonstrated by the expression of microglial genes, innate immune responses, chemotaxis, and phagocytic abilities. …”
Get full text
Article -
560
To Determine the Role of Human Papillomavirus in Oral Cancer—A Prospective Study
Published 2024-12-01“…The presence of HPV causes molecular damage in cells, thereby resulting in cell proliferation and malignant conversions. Therefore, we can conclude that the human papillomavirus significantly contributes to carcinogenesis. …”
Get full text
Article