Study on Apoptosis of Prostate Cancer Cells Induced by IκBα Overexpression Synergistic with Poly (Lactic-Co-Glycolic Acid)-Curcumin Nanoparticles by Hui Guo, Jianwen Huang, Hongbin Li, Ranxing Yang, Rong Chen

“…The expression levels of IκBα, apoptosis-related, and signaling proteins were measured by western blotting assay. Results. PC cell proliferation was significantly inhibited by the overexpression of IκBα. …”
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Increased Apoptosis and Proliferative Capacity are Early Events in Cyst Formation in Autosomal-Dominant, Polycystic Kidney Disease by Salwa Ibrahim

“…In this study, we sought to evaluate the timing and extent of these changes in renal tissue obtained from patients with autosomal-dominant, polycystic kidney disease (ADPKD) subjected for nephrectomy for a variety of clinical indications. Cell proliferation was assessed using an antibody to proliferating cell nuclear antigen (PCNA), and apoptosis was evaluated by the use of terminal deoxynucleotidyl transferase (TdT) digoxigenin-deoxyuridine (dUTP) nick end-labeling technique (ApopTag®). …”
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In Vitro 3D Models of Haematological Malignancies: Current Trends and the Road Ahead? by Carlotta Mattioda, Claudia Voena, Gianluca Ciardelli, Clara Mattu

“…In the last decades, it was largely demonstrated that the tumor microenvironment significantly affects cancer cell proliferation and tumor response to treatment. The development of biomimetic, in vitro models may promote the investigation of the interactions between cancer cells and the tumor microenvironment and may help to better understand the mechanisms leading to drug resistance. …”
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Dasatinib enhances curcumin-induced cytotoxicity, apoptosis and protective autophagy in human schwannoma cells HEI-193: The role of Akt/mTOR/p70S6K signalling pathway by Pang Pengfei, Zhang Shirong

“…Cellular toxicity, cell proliferation, and cell death were determined by LDH, MTT, and trypan blue dye assays, respectively. …”
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Emerging Delivery Strategies of Platelet-Rich Plasma with Hydrogels for Wound Healing by Ya Zhang, Zi-Lin Wang, Ze-Peng Deng, Zi-Li Wang, Fei Song, Li-Li Zhu

“…Platelet-rich plasma (PRP), a platelet-rich plasma concentrate obtained from whole blood, has been widely used to treat wounds due to its high contents of growth factors that can not only play a role in the hemostasis, repair, and anti-infection of wounds but also promote cell proliferation, maturation, and angiogenesis. However, after PRP activation, its clinical effect was limited because of burst and uncontrolled release of growth factors and poor mechanical properties of PRP gels. …”
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Th22 Cells/IL-22 Serves as a Protumor Regulator to Drive Poor Prognosis through the JAK-STAT3/MAPK/AKT Signaling Pathway in Non-Small-Cell Lung Cancer by Yinan Yao, Guangdie Yang, Guohua Lu, Jiani Ye, Luyun Cui, Zhu Zeng, Junjun Chen, Jianying Zhou

“…Furthermore, IL-22 not only antagonized the apoptosis inducing and cell cycle arresting effect by chemotherapy and molecular targeted drugs on NSCLC cell lines but also promoted tumor cell proliferation and tumor tissue growth. Moreover, IL-22 activated the JAK-STAT3/MAPK/AKT signaling pathway, both in vitro and in vivo. …”
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Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. by Tonibelle Gatbonton, Maria Imbesi, Melisa Nelson, Joshua M Akey, Douglas M Ruderfer, Leonid Kruglyak, Julian A Simon, Antonio Bedalov

“…We also found 39 genes that have an important role in telomere maintenance or cell proliferation in the absence of telomerase, including genes that participate in deoxyribonucleotide biosynthesis, sister chromatid cohesion, and vacuolar protein sorting. …”
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ASPM Promotes the Progression of Anaplastic Thyroid Carcinomas by Regulating the Wnt/β-Catenin Signaling Pathway by Liang Jiang, Shuai Zhang, Ning An, Guoqing Chai, Changhong Ye

“…The effect of ASPM on cell proliferation, migration, invasion, and cell cycle was explored in ATC cell lines by in vitro inhibition of ASPM, while ASPM-mediated tumorigenicity was investigated in a xenograft tumor model. …”
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Magnetic Resonance Imaging of Cells Overexpressing MagA, an Endogenous Contrast Agent for Live Cell Imaging by Donna E. Goldhawk, Claude Lemaire, Cheryl R. McCreary, Rebecca McGirr, Savita Dhanvantari, R. Terry Thompson, Rene Figueredo, Jim Koropatnick, Paula Foster, Frank S. Prato

“…MagA expression augmented both Prussian blue staining and the elemental iron content of N2A cells, without altering cell proliferation, in cultures grown in the presence of iron supplements. …”
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Alcohol and cancer: the role of cytochrome P-4502E1 by Helmut K. Seitz, Bernardo Moreira, Manuela Neuman

“…CYP2E1 is also responsible for the degradation of retinol and retinoic acid (RA), which is associated with changes in cell differentiation, cell proliferation and apoptosis, leading to a precancerous cell cycle behaviour. …”
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A structural model of the VEGF signalling pathway: Emergence of robustness and redundancy properties by Floriane Lignet, Vincent Calvez, Emmanuel Grenier, Benjamin Ribba

“…The model, built on qualitative information from knowledge databases, is composed of 38 ordinary differential equations with 78 parameters and focuses on the signalling driving endothelial cell proliferation, migration and resistance to apoptosis. …”
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Role of Stat3 in Skin Carcinogenesis: Insights Gained from Relevant Mouse Models by Everardo Macias, Dharanija Rao, John DiGiovanni

“…Stat3 plays critical roles in various biological activities including cell proliferation, migration, and survival. Studies using keratinocyte-specific Stat3-deficient mice have revealed that Stat3 plays an important role in skin homeostasis including keratinocyte migration, wound healing, and hair follicle growth. …”
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Discrimination of Anti-Donor Response in Allogeneic Transplantation Using an Alloreactive T-Cell Detection Assay by Ryosuke Arata, Naoki Tanimine, Akhmet Seidakhmetov, Kentaro Ide, Yuka Tanaka, Hideki Ohdan

“…Overall, although the conventional readout for evaluating T-cell proliferation following an MLR quantifies the precursor frequency of alloreactive T cells, the assay reported herein assesses T-cell activation markers after a short-term MLR to characterize immediate immune status. …”
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Induction of Cell Activation Processes by Low Frequency Electromagnetic Fields by Myrtill Simkó

“…Modification in cell proliferation was observed after EMF exposure and a few reports on cytotoxic effects have also been published. …”
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Effects of exosomes from human dental pulp stem cells on the biological behavior of human fibroblasts by Guan-Yu Chen, Ling-ling Fu, Hui-ping Ye, Ping Cheng, Hong-chao Feng, Ming Yan

“…We detected its effect on cell proliferation using the CCK-8 assay; cell migration ability by cell scratch and Transwell assays; extracellular matrix synthesis using the hydroxyproline content assay; the expression levels of genes associated with fibrosis by PCR assay; and the expression levels of proteins related to fibrosis in the cells using the Western Blot method. …”
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Proteomic Analysis of Exudates from Chronic Ulcer of Diabetic Foot Treated with Scorpion Antimicrobial Peptide by Zhixiang Tan, Zhiguo Yu, Xiaobo Xu, Lanxia Meng, Mosheng Yu, Rui Tao, Yingliang Wu, Zhanyong Zhu

“…The results showed that the biochemical changes of wound microenvironment during the treatment involved activated biological functions such as protein synthesis, cell proliferation, differentiation, migration, movement, and survival. …”
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Structure simulation-based comparison of active site variations in fungal ornithine decarboxylases by Min Jeong Kim, Jeong Ho Chang

“…Polyamines play crucial roles in various biological processes, including cell proliferation and differentiation, immune response modulation, and signal transduction. …”
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TNPO1-Mediated Nuclear Import of FUBP1 Contributes to Tumor Immune Evasion by Increasing NRP1 Expression in Cervical Cancer by BiKang Yang, Jing Chen, YinCheng Teng

“…In vitro, functional experiments showed that knockdown of FUBP1 inhibited CC cell proliferation and migration. Therefore, FUBP1 plays a prooncogenic function in CC progression. …”
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Polymeric Scaffolds in Tissue Engineering Application: A Review by Brahatheeswaran Dhandayuthapani, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar

“…To restore function or regenerate tissue, a scaffold is necessary that will act as a temporary matrix for cell proliferation and extracellular matrix deposition, with subsequent ingrowth until the tissues are totally restored or regenerated. …”
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Identification of key regulators in pancreatic ductal adenocarcinoma using network theoretical approach. by Kankana Bhattacharjee, Aryya Ghosh

“…Our analysis revealed 33 key regulators were predominantly enriched in neuroactive ligand-receptor interaction, Cell adhesion molecules, Leukocyte transendothelial migration pathways; positive regulation of cell proliferation, positive regulation of protein kinase B signaling biological functions; G-protein beta-subunit binding, receptor binding molecular functions etc. …”
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