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441
Cytotoxicity and Antiangiogenic Activity of Turbinaria ornata Agardh and Padina australis Hauck Ethanolic Extracts
Published 2018-01-01“…Brown macroalgae species are constantly reported as potential sources of bioactive compounds useful in inhibiting cell proliferation and vascular formation. Thus, this study was conducted to determine and compare the in vitro cytotoxic activities of Turbinaria ornata Agardh and Padina australis Hauck ethanolic extracts against baker’s yeast (Saccharomyces cerevisiae) using the resazurin reduction test (RRT) and investigate their in vivo antiangiogenic activity through duck (Anas platyrhynchos) chorioallantoic membrane (CAM) assay. …”
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442
The RNA-binding protein Modulo promotes neural stem cell maintenance in Drosophila.
Published 2024-01-01“…Stem cells that remain lack expression of key NB identity factors and exhibit cell proliferation defects. Mechanistically, our analysis suggests these deficiencies arise at least in part from altered cell cycle progression, with a proportion of NBs arresting prior to mitosis. …”
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443
Seroprevalence and pathological investigation of salmonellosis in poultry
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444
Endogenous Proliferation after Spinal Cord Injury in Animal Models
Published 2012-01-01“…All SCI animal models experience a similar peak of cell proliferation three days after injury; however, each specific type of injury promotes a specific and distinct stem cell response. …”
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445
The Mammary Gland Carcinogens: The Role of Metal Compounds and Organic Solvents
Published 2013-01-01“…The four most predominant mechanisms for metal carcinogenicity include (1) interference with cellular redox regulation and induction of oxidative stress, (2) inhibition of major DNA repair, (3) deregulation of cell proliferation, and (4) epigenetic inactivation of genes by DNA hypermethylation. …”
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446
Perioperative Management of Patient with Systemic Mastocytosis Going for Total Thyroidectomy
Published 2025-01-01“… Systemic mastocytosis (SM) is a rare disorder affecting 1 in 10,000 individuals, characterised by abnormal mast cell proliferation in extra-cutaneous organs, resulting in a variety of presentations ranging from mild asymptomatic disease to life-threatening tissue-destructive disease. …”
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447
Wnt5a Signaling in Normal and Cancer Stem Cells
Published 2017-01-01“…Recent studies show the involvement of Wnt5a signaling in regulating normal and cancer stem cell self-renewal, cancer cell proliferation, migration, and invasion. In this article, we review recent findings regarding the molecular mechanisms and roles of Wnt5a signaling in stem cells in embryogenesis and in the normal or neoplastic breast or ovary, highlighting that Wnt5a may have different effects on target cells depending on the surface receptors expressed by the target cell.…”
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448
Exploring Long Noncoding RNAs in Glioblastoma: Regulatory Mechanisms and Clinical Potentials
Published 2018-01-01“…The WHO grade IV glioblastoma (GBM), characterized by rapid cell proliferation, easily recrudescent, high morbidity, and mortality, is the most common, devastating, and lethal gliomas. …”
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449
Positive and Negative Regulation of Cellular Immune Responses in Physiologic Conditions and Diseases
Published 2012-01-01“…In the presence of a pathogen, a specific and effective immune response must be induced and this leads to antigen-specific T-cell proliferation, cytokines production, and induction of T-cell differentiation toward an effector phenotype. …”
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450
Neutrophil-Derived IL-6 Potentially Drives Ferroptosis Resistance in B Cells in Lupus Kidney
Published 2023-01-01“…Moreover, we identified that in lupus kidney, neutrophils could provide IL-6 to facilitate ferroptosis resistance in B cells via SLC7A11, and inhibition of SLC7A11 could significantly enhance ferroptosis in B cells and could decrease B cell proliferation. This study helps understand the crosstalk between neutrophils and B cells in the kidney in the development of lupus.…”
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451
Cytokine Secretion of Peripheral Blood Mononuclear Cells by Hydnocarpus anthelminthicus Seeds
Published 2018-01-01“…Cell viability was detected with WST-1 cell proliferation assay reagent. Proinflammatory cytokines were quantified using ELISA with a specific antibody. …”
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452
The role of complement in tumor immune tolerance and drug resistance: a double-edged sword
Published 2025-01-01“…On the one hand, the complement system has the capacity to directly inhibit cancer cell proliferation via specific pathways, thereby exerting a beneficial anti-tumor effect. …”
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453
ATP-Dependent Chromatin Remodeling Complex in the Lineage Specification of Mesenchymal Stem Cells
Published 2020-01-01“…Key events, including cell proliferation, lineage commitment, and MSC differentiation, are ensured by precise gene expression regulation. …”
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454
A review on the potential of Bruton’s tyrosine kinase (Btk) inhibitor – Ibrutinib for treatment of Multiple Myeloma (MM)
Published 2019-05-01“…In MM patients, it has been reported that the expression of Btk was elevated and this could potentially contribute to chemoresistance indirectly via enhancement of cell proliferation and survival. Ibrutinib is a highly selective irreversible Btk inhibitor commonly used as treatment for B-cell malignancies such as Mantle Cell Lymphoma (MCL) and Chronic Lymphocytic Leukemia (CLL). …”
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455
Enhanced antibody responses in CD19-Cre mice
Published 2025-01-01“…In vitro, we observed enhanced class-switch recombination and a moderate reduction in B cell proliferation upon LPS and IFNγ stimulation, yet no drastic differences in BCR signalling. …”
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456
“Dead Cells Talking”: The Silent Form of Cell Death Is Not so Quiet
Published 2012-01-01“…We will discuss evidence suggesting that cancer cell proliferation may be driven by inappropriate or corrupted tissue-repair programmes that are initiated by signals from apoptotic cells and show how this may dramatically modify how we view the role of apoptosis in both tumourigenesis and cancer therapy.…”
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457
AhR governs lipid metabolism: the role of gut microbiota
Published 2025-01-01“…Under physiological conditions, AhR mainly participates in regulating the body’s immune response, cell proliferation, and apoptosis among a series of processes. …”
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458
Tumour Immunotherapy and Applications of Immunological Products: A Review of Literature
Published 2024-01-01“…Malignant tumors, characterized by uncontrolled cell proliferation, are a leading global health challenge, responsible for over 9.7 million deaths in 2022, with new cases expected to rise to 35 million annually by 2050. …”
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459
A Review on the Antimutagenic and Anticancer Effects of Cysteamine
Published 2023-01-01“…Although the mechanisms of action are not fully understood, possible explanations are (i) free radical scavenging, (ii) alteration of the tumor cell proliferation by affecting nucleic acid and protein synthesis or inhibition of DNA synthesis, and (iii) hormone regulation. …”
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460
Purple corn extract improves benign prostatic hyperplasia by inhibiting 5 alpha-reductase type 2 and inflammation in testosterone propionate-induced rats
Published 2025-01-01“…In these rats, PCE decreased androgen receptor (AR) expression, AR-mediated signaling, and cell proliferation and increased apoptotic cell death. Finally, PCE exhibited anti-inflammatory activity through the regulation of the nuclear factor-kappa B (NF-κB) and nuclear factor erythroid 2-related factor 2 (Nrf-2) axis. …”
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