More than just a number: the gut microbiota and brain function across the extremes of life by Nathan D. Nuzum, Clara Deady, Sarah Kittel-Schneider, John F. Cryan, Siobhain M. O'Mahony, Gerard Clarke

“…In neurodegeneration research, strong causal evidence now links the gut microbiome to Alzheimer's (AD), and Parkinson's Disease (PD), as supported by human-to-animal transplantation studies. …”
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Neurobiological Mechanisms Underlying Psychological Dysfunction After Brain Injuries by Prashin Unadkat, Tania Rebeiz, Erum Ajmal, Vincent De Souza, Angela Xia, Julia Jinu, Keren Powell, Chunyan Li

“…Furthermore, it underscores significant gaps, particularly the inadequate consideration of interactions among causal factors, environmental influences, and individual susceptibilities. …”
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Warming-driven migration of enterotypes mediates host health and disease statuses in ectotherm Litopenaeus vannamei by Shenzheng Zeng, Zhijian Huang, Satapornvanit Kriengkrai, Renjun Zhou, Derun Yuan, Nguyễn Văn Tuấn, Zhiming Zhu, Luwei Zheng, Qilu Hou, Xuanting Li, Qi Chen, Lingyu Zhang, Dongwei Hou, Zhixuan Deng, Shicheng Bao, Wenjun Wang, Sukontorn Khoruamkid, Soo Loon Goh, Shaoping Weng, Jianguo He

“…Collectively, the warming-driven enterotypes mediated shrimp health, which exemplified the causal relationship between temperature rising and ectothermic animals’ health. …”
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Association of Helicobacter pylori Infection with Coronary Artery Disease: Is Helicobacter pylori a Risk Factor? by Jamshid Vafaeimanesh, Seyyed Fakhroldin Hejazi, Vahid Damanpak, Mostafa Vahedian, Mohammadamin Sattari, Mohammadreza Seyyedmajidi

“…HP infection is more prevalent in CAD positive patients and, in case of proving causal relationship, it can be considered as a reversible risk factor for CAD.…”
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A cross-tissue transcriptome-wide association study identified susceptibility genes for age-related macular degeneration by Hongfan Yang, Haofei Huang, Kunlin Pu

“…Multi-marker Analysis of Genomic Annotation (MAGMA) was employed to validate results and identify reliable susceptibility genes, followed by summary data-based Mendelian randomization (SMR) and colocalization analyses to explore causal associations. The cross-tissue and single-tissue TWAS analyses identified 12 reliable AMD-associated genes. …”
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Disease suppression is driven by microbial community properties at fine taxonomic scales by Shan Shan, Isabelle George, Michael D. Millican, Linda L. Kinkel, Richard A. Lankau

“…In a greenhouse study, we grew potato plants in pots sharing a common background soil and inoculated with living soil microbial communities with or without a separate inoculation with Streptomyces scabiei, the causal agent of potato common scab disease. The suppression of common scab and growth promotion abilities of a variety of soil microbial communities were estimated and related to quantitative patterns in microbial community structure. …”
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Genetic Variants in the SCN9A Gene are Detected in a Minority of Erythromelalgia Patients by Mari Skystad Kvernebo, Celene Grayson, Ioannis M. Stylianou, Virginia Woloshen, Christopher Radomski, Cato Mørk, Knut Kvernebo

“…Five were found to carry likely causal variants, including a variant found in 2 related individuals and a variant not previously described in patients with erythromelalgia. …”
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Replication of the Association of the 6q22.31c Locus near with Pulse Rate in the Korean Population by Nam Hee Kim, Young Jin Kim, Ji Hee Oh, Yoon Shin Cho

“…GJA1 was implied as a functionally causal gene for pulse rate from the KARE study, but lacked evidence of replication. …”
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Is Weight-Bearing Asymmetry Associated with Postural Instability after Stroke? A Systematic Review by Jip F. Kamphuis, Digna de Kam, Alexander C. H. Geurts, Vivian Weerdesteyn

“…Greater WBA after stroke was associated with increased postural sway, but the current literature does not provide evidence for a causal relationship. Further studies should investigate whether reducing WBA would improve postural stability.…”
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A theory-driven framework for the design and implementation of successful agri-environmental programmes: results of a realist review by Bibi Witvliet, Huub Ploegmakers, Sander Meijerink

“…We performed a realist review to identify causal relationships between agri-environmental strategies (S), their outcomes (O), and the contextual factors (C) and motivational mechanisms (M) that explain how, when and why AEP outcomes were achieved. …”
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Conceptualizing and Presenting a Paradigm Model of Advertising Strategies for Cosmetics and Health Products in Iran's Online Space by Ayoub Pazhouhan, Latifeh Jaferi

“…It is suggested to pay attention to the paradigm model and its components, especially the causal factors, background and strategies, in order to develop advertising strategies for cosmetics and health products in Iran's online space.Originality/Value:  Few studies have been conducted on the advertising strategies of cosmetics and health products in Iran's online space, especially with a qualitative approach, and there is no practical and systematic model or framework in this field, so this study tries to solve this theoretical and research gap to some extent and provide advertising strategies for the health and cosmetic industries in Iran's online space for the marketing and sales managers of the mentioned industries.…”
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Analytical approaches to evaluate risk factors of multimorbidity: a systematic scoping review protocol by Alex Lewin, Poppy Alice Carson Mallinson, Sanjay Kinra, Judith Lieber, Chaisiri Angkurawaranon, Hirotomo Yamanashi, Chanchanok Aramrat, Nutchar Wiwatkunupakarn, Nick Birk, Wenbo Song, Mika Matsuzaki, Elliott Rogers

“…Introduction Understanding causal risk factors that contribute to the development of multimorbidity is essential for designing and targeting effective preventive strategies. …”
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Electroencephalographic and Epilepsy Findings in ZNF711 Variants: A Case Series of Two Siblings by Michele Minerva, Lorenzo Perilli, Samanta Carbone, Margherita Maria Rossi, Federica Lotti, Luisa Lonoce, Maria Rosaria Curcio, Salvatore Grosso

“…Conclusions: This case expands the clinical range of ZNF711 variants by highlighting epilepsy as a potential comorbidity and suggesting other possible causal candidates for generalized epilepsy. Moreover, it emphasizes the need for further research into the phenotypic spectrum associated with this variant.…”
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Investigative model of repurchase intention on boycott brand of multinational franchise food and beverage in Indonesia by Mohamad Rizan, Agung Kresnamurti, Farah Chalida Hanoum, Raka Pria Anugrah, Heri Prabowo, Qristin Violinda, Guruh Ghifar Zalzalah, Hapsari Dyah Herdiany

“…Following the boycott movement against certain foreign-brand food and beverage goods, the impact of religious beliefs, hostility, and the perception of the country of origin define this process. A causal/explanatory survey was employed as the research method. …”
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DNA replication stress underpins the vulnerability to oxidative phosphorylation inhibition in colorectal cancer by Xiao Hong Zhao, Man Man Han, Qian Qian Yan, Yi Meng Yue, Kaihong Ye, Yuan Yuan Zhang, Liu Teng, Liang Xu, Xiao-Jing Shi, Ting La, Yu Chen Feng, Ran Xu, Vinod K. Narayana, David P. De Souza, Lake-Ee Quek, Jeff Holst, Tao Liu, Mark A. Baker, Rick F. Thorne, Xu Dong Zhang, Lei Jin

“…The addition of purine nucleobases adenine and guanine along with the pyrimidine nucleoside uridine restored replication fork progression and cell proliferation, whereas the supplementation of exogenous aspartate recovered the nucleotide pool, demonstrating a causal role of the aspartate shortage in OXPHOS inhibition-induced nucleotide deficiencies and consequently replication stress and reductions in proliferation. …”
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Effects of vegetable commercialization on household food security: a generalized propensity score matching approach by Asfaw Shaka Gosa, Tebarek Lika Megento, Meskerem Abi Teka

“…This study used a Generalized Propensity Score Matching (GPSM) approach to evaluate the average causal effects of vegetable commercialization levels on the food security status of households in Sabbata Hawas Woreda, Oromia Region, Ethiopia. …”
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Inuit uses of weather, water, ice, and climate indicators to assess travel safety in Arctic Canada, Alaska, and Greenland: a scoping review by Breanna Bishop, Emmelie Paquette, Natalie Carter, Gita Ljubicic, Eric C.J. Oliver, Claudio Aporta

“…Indicators can be considered as causal, conditional, or predictive (or a combination thereof), where knowledge of the interactions among various indicators is especially important to support safe travel. …”
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Women in business: The impact of digital and financial literacy on female-owned small and medium-sized enterprises by Nadia Asandimitra, Achmad Kautsar, Dewie Tri Wijayati, Nunik Dwi Kusumawati, Ina Uswatun Nihaya

“…Financial and digital capability are examined as mediators between performance and these factors. The study used a causal explanatory research approach. The data in this study were collected through questionnaires. …”
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The Impact of Land Development Rights Transfer on Urban–Rural Spatial Justice: A Case Study of Chongqing’s Land Quota Trading by Siyi Wei, Jing Huang, Zhanlu Zhang

“…Using the Chongqing land quota trading pilot as the core case, we apply synthetic control methods to analyze the causal effects of this policy. The results show that LDR transfer promotes urban–rural spatial resources equity in the short term, particularly through the marketization of land transactions. …”
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Sonication: A Valuable Technique for Diagnosis and Treatment of Periprosthetic Joint Infections by D. S. Evangelopoulos, I. P. Stathopoulos, G. P. Morassi, S. Koufos, A. Albarni, P. K. Karampinas, A. Stylianakis, S. Kohl, S. Pneumaticos, J. Vlamis

“…Identification of the causal microbial factor is of paramount importance for the successful treatment. …”
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