The relationship between DNA fragmentation and the intensity of morphologically abnormal human spermatozoa by Mercedes González-Martínez, Pascual Sánchez-Martín, Carmen López-Fernández, Stephen D. Johnston, Jaime Gosálvez

“…Conclusions: Although analysis of a more continuous range of values for teratozoospermia would help further clarify any causal relationship with SDF, there is clearly a synergistic or coincident affiliation between these variables that needs to be acknowledged by the clinician when interpreting the spermiogram.…”
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A research on academic self-perception and academic achievement of secondary school students by Şenay Bozdağ, Sümer Aktan

“…A predictive correlational research design and causal comparison methods were employed. The sample consisted of 906 volunteer seventh-grade students from public secondary schools in Altıeylül and Karesi, Balıkesir Province. …”
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Environmental Influences on Young Adult Male Height. A Comparison of Town and Countryside in the Netherlands, 1815-1900 by Jan Kok, Erik Beekink, David Bijsterbosch

“…But how was urban residence connected to height? Causal mechanisms can include disease environment related to crowdedness, food availability or the nature of urban versus rural work. …”
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Triglyceride levels and its association with all-cause mortality and cardiovascular outcomes among patients with heart failure by Qing-Wen Ren, Tiew-Hwa Katherine Teng, Wouter Ouwerkerk, Yi-Kei Tse, Christopher Tze Wei Tsang, Mei-Zhen Wu, Hung-Fat Tse, Adriaan A. Voors, Jasper Tromp, Carolyn S. P. Lam, Kai-Hang Yiu

“…Abstract Remnant cholesterol, identified by triglyceride-rich lipoprotein, is a significant causal risk factor for ischemic heart diseases. The association of triglyceride levels with all-cause and cause-specific outcomes in heart failure (HF) remains unexplored. …”
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Adaptive period decomposition network with muti-scale temporal variation learning for water level prediction by Hui Wang, LiPing Wang, QiCang Qiu, Yuyan Gao, WenJuan Li, QiuShun Wang

“…The model incorporates a 2D overlap patch attention mechanism and separable dilation causal convolution to effectively capture local and global temporal variations. …”
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Complement activated granulocytes can cause autologous tissue destruction in man by E. Löhde, H. Raude, M. Lück, E. Kraas, W. Lierse

“…These data support the concept that C5a activated PMNs can cause endothelial and mesothelial damage in man. Even though a causal relationship between anaphylatoxins and organ failure cannot be proved by these experiments C5a seems to be an important mediator in the pathogenesis of changes induced by severe sepsis and trauma in man.…”
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First Report on the Emergence of <i>Neopestalotiopsis rosae</i> as a Severe Economic Threat to Strawberry Production in Germany by Tom E. Schierling, Ralf T. Voegele, Abbas El-Hasan

“…A combination of morphological and molecular analyses, along with pathogenicity tests, confirmed the identity of <i>N. rosae</i> as the causal agent. Morphological examination of conidia and mycelium revealed key characteristics including the presence of versicolorous median cells, conidial appendages, black spherical conidiomata formation as well as changing colony color and fluffy texture. …”
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Exome Sequencing Identified a Recessive RDH12 Mutation in a Family with Severe Early-Onset Retinitis Pigmentosa by Bo Gong, Bo Wei, Lulin Huang, Jilong Hao, Xiulan Li, Yin Yang, Yu Zhou, Fang Hao, Zhihua Cui, Dingding Zhang, Le Wang, Houbin Zhang

“…Exome sequencing was performed on a single RP patient (the proband of this family) and direct Sanger sequencing on other family members and normal controls was followed to confirm the causal mutations. A homozygous mutation c.437T<A (p.V146D) in the retinol dehydrogenase 12 (RDH12) gene, which encodes an NADPH-dependent retinal reductase, was identified as being related to the phenotype of this arRP family. …”
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Factors affecting fatigue progression in multiple sclerosis patients by Dima Machtoub, Callie Fares, Hassan Sinan, Moustafa Al Hariri, Rim Nehme, Joelle Chami, Ronny Joukhdar, Raya Tcheroyan, Salim Adib, Samia J. Khoury

“…Further studies are needed in order to elucidate a causal relationship and determine whether the management of fatigue in patients with MS should include interventions that address the aforementioned variables to optimize patient care and improve quality of life.…”
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Alterations in Monocyte CD16 in Association with Diabetes Complications by Danqing Min, Belinda Brooks, Jencia Wong, Robert Salomon, Wensheng Bao, Brian Harrisberg, Stephen M. Twigg, Dennis K. Yue, Susan V. McLennan

“…These changes may be causally related to and could potentially be used to predict susceptibility to diabetic complications.…”
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Bilateral chemogenetic activation of intratelencephalic neurons in motor cortex reduces spontaneous locomotor activity in mice by Mihai Atudorei, Christian del Agua Villa, Ulrik Gether, Maria Angela Cenci, Hartwig Roman Siebner, Mattias Rickhag

“…The results establish a causal link between the activity level of intratelencephalic neurons in the motor cortex, spontaneous locomotor activity in the open field, and the dopamine system. …”
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The association of gut microbiota, immunocyte dynamics, and protein–protein ratios with tuberculosis susceptibility: a Mendelian randomization analysis by Hanxin Wu, Weijie Ma, Liangyu Zhu, Li Peng, Xun Huang, Lei Zhong, Rui Yang, Bingxue Li, Weijiang Ma, Li Gao, Xinya Wu, Jieqin Song, Suyi Luo, Fukai Bao, Aihua Liu

“…Abstract This study focused on the relationships among gut microbiota, plasma protein ratios, and tuberculosis. Given the unclear causal relationship between gut microbiota and tuberculosis and the scarcity of research on relevant plasma protein ratios in tuberculosis, Mendelian randomization analysis (MR) was employed for in-depth exploration. …”
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Novel mitochondrial-targeted alkyl chains act as fungal specific inhibitors of C. neoformans by Elizabeth S. M. Edrich, Luke Young, John Spencer, Andrew McGown, Anthony L. Moore, Campbell W. Gourlay

“…Cryptococcus neoformans is the causal agent of cryptococcal meningitis in immunocompromised patients and increasing instances of anti-fungal resistance have led to investigations into new alternative antifungal targets. …”
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Genetic analyses identify circulating genes related to brain structures associated with Parkinson’s disease by Zhe Han, Yanping Zhu, Zhenhong Xia, Qing Deng, Hongjie He, Quanting Yin, Hui Zhang, Mudan Yuan, Chunhua Yang, Geng Tian, Jia Mi, Fuyi Xu

“…Additionally, 1345 circulating genes causally linked with white matter tract diffusivity were enriched for muscle physiological abnormalities (padj < 0.05). …”
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Obtaining personalized predictions from a randomized controlled trial on Alzheimer’s disease by Dennis Shen, Anish Agarwal, Vishal Misra, Bjoern Schelter, Devavrat Shah, Helen Shiells, Claude Wischik

“…The SNN estimator is interpretable, transparent, and causally justified under a broad class of missing data scenarios. …”
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Genome-wide association analysis of composite sleep health scores in 413,904 individuals by Matthew O. Goodman, Tariq Faquih, Valentina Paz, Pavithra Nagarajan, Jacqueline M. Lane, Brian Spitzer, Matthew Maher, Joon Chung, Brian E. Cade, Shaun M. Purcell, Xiaofeng Zhu, Raymond Noordam, Andrew J. K. Phillips, Simon D. Kyle, Kai Spiegelhalder, Michael N. Weedon, Deborah A. Lawlor, Jerome I. Rotter, Kent D. Taylor, Carmen R. Isasi, Tamar Sofer, Hassan S. Dashti, Martin K. Rutter, Susan Redline, Richa Saxena, Heming Wang

“…Post-GWAS analyses uncover novel genetic mechanisms underlying sleep health and reveal connections (including potential causal links) to behavioral, psychological, and cardiometabolic traits.…”
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TREMSUCS-TCGA – an integrated workflow for the identification of biomarkers for treatment success by Balogh Gabor, Jorge Natasha, Dupain Célia, Kamal Maud, Servant Nicolas, Le Tourneau Christophe, Stadler Peter F., Bernhart Stephan H.

“…The best ranked biomarker candidates are discussed in the light of the existing literature, indicating plausible causal relationships to the relevant cancer entities.…”
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Short Reads Phasing to Construct Haplotypes in Genomic Regions That Are Associated with Body Mass Index in Korean Individuals by Kichan Lee, Seonggyun Han, Yeonjeong Tark, Sangsoo Kim

“…Since these studies are useful to investigate untyped but causal variants using linkage disequilibrium (LD), it would be useful to explore the haplotypes of single-nucleotide polymorphisms (SNPs) within the same LD block of significant associations based on high-density variants from population references. …”
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Probiotics administration alleviates cognitive impairment and circadian rhythm disturbance induced by sleep deprivation by Peijun Tian, Yunfei Hou, Zheng Wang, Jiaona Jiang, Xin Qian, Zhihao Qu, Jianxin Zhao, Gang Wang, Wei Chen

“…Specifically, gut microbiota plays a causal role in sleep deprivation (SD)-induced cognitive impairment. …”
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Satellite Observations Reveal Declining Diatom Concentrations in the Three Gorges Reservoir: The Impacts of Dam Construction and Local Climate by Menglan Gan, Lei Feng, Jingan Shao, Li Feng, Yao Wang, Meiling Liu, Ling Wu, Botian Zhou

“…The results indicate that a synchronous diatom distribution is found between the upstream and downstream artificial lakes along the primary tributary in the Three Gorges Reservoir, and the causal relationships between the declining diatom trend and hydrological/meteorological drivers on the monthly and yearly scales are highlighted. …”
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