Genetic code expansion reveals site-specific lactylation in living cells reshapes protein functions by Chang Shao, Shuo Tang, Siqin Yu, Chenguang Liu, Yueyang Zhang, Tianyan Wan, Zimeng He, Qi Yuan, Shihan Wu, Hanqing Zhang, Ning Wan, Mengru Zhan, Ren Xiang Tan, Haiping Hao, Hui Ye, Nanxi Wang

“…Our findings highlight the utility of the GCE-based workflow in establishing causal relationships between specific lactylation events and both target-specific and cell-wide changes, advancing our understanding of protein lactylation’s functional impact.…”
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The mycobiome in human cancer: analytical challenges, molecular mechanisms, and therapeutic implications by Ting Ding, Chang Liu, Zhengyu Li

“…This review aims to elucidate the causal and complicit roles of mycobiome in cancer development and progression while highlighting the issues that need to be addressed in executing such research. …”
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Causes and solutions for fruit and vegetable waste: a participatory approach with Romanian farmers for sustainable agriculture by Ruxandra Malina Petrescu-Mag, Dacinia Crina Petrescu, Iulia Ajtai, Carmen Andreea Roba, Oana Adriana Gica, Lucian Cuibus, Ancuta Tenter, Valentin Toader, Adina Letitia Negrusa, Nicoleta Bican-Brișan

“…The results of the qualitative research methods, including one to one interviews and a community-based causal analysis (CBCA) process, showed that farmers defined FV waste as discarded produce, excluding items used for compost or animal feed. …”
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Dynamic representation of appetitive and aversive stimuli in nucleus accumbens shell D1- and D2-medium spiny neurons by Ana Verónica Domingues, Tawan T. A. Carvalho, Gabriela J. Martins, Raquel Correia, Bárbara Coimbra, Ricardo Bastos-Gonçalves, Marcelina Wezik, Rita Gaspar, Luísa Pinto, Nuno Sousa, Rui M. Costa, Carina Soares-Cunha, Ana João Rodrigues

“…Optogenetic manipulation of D2-MSNs provided causal evidence of the necessity of this population in the extinction of aversive associations. …”
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Latanoprost Induced Iris Pigment Epithelial and Ciliary Body Cyst Formation in Hypermetropic Eyes by Abhijit Anand Mohite, Rangarajan V. Prabhu, Thomas Ressiniotis

“…The cysts subsided with discontinuation of Latanoprost, thereby demonstrating a causal relationship. We discuss the pathogenesis of such cysts and advocate using of serial ultrasound biomicroscopic (UBM) images to monitor them. …”
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Systematic Review of the Relationship between Acute and Late Gastrointestinal Toxicity after Radiotherapy for Prostate Cancer by Matthew Sean Peach, Timothy N. Showalter, Nitin Ohri

“…In this systematic review of published reports, we found that late gastrointestinal toxicity following prostate radiotherapy seems to be statistically and potentially causally related to acute gastrointestinal morbidity as a consequential effect. …”
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Investigating the Structural Model of Predicting Sleep Disorders Through Symptoms of Rumination with the Mediating Role of Social Support in Dialysis Patients by Farhad Ghorbani, Amin Rafiepoor, Niloufar Tahmouresi, Reza, Hosseinpour

“…Therefore, it is essential to focus on identifying and addressing the effective and causal factors when developing therapeutic interventions for these sleep disorders.…”
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Bidirectional relationship between epigenetic age and stroke, dementia, and late-life depression by Cyprien A. Rivier, Natalia Szejko, Daniela Renedo, Santiago Clocchiatti-Tuozzo, Shufan Huo, Adam de Havenon, Hongyu Zhao, Thomas M. Gill, Kevin N. Sheth, Guido J. Falcone

“…Mendelian Randomization analyses replicate these findings, supporting their causal nature. Our results support using epigenetic age as a biomarker to evaluate interventions aimed at preventing and promoting recovery after brain health events.…”
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Multiple Sclerosis and Obesity: Possible Roles of Adipokines by José de Jesús Guerrero-García, Lucrecia Carrera-Quintanar, Rocío Ivette López-Roa, Ana Laura Márquez-Aguirre, Argelia Esperanza Rojas-Mayorquín, Daniel Ortuño-Sahagún

“…Once MS is initiated, obesity can contribute to increased disease severity by negatively influencing disease progress and treatment response, but, also, obesity in early life is highly relevant as a susceptibility factor and causally related risk for late MS development. The aim of this review was to discuss recent evidence about the link between obesity, as a chronic inflammatory state, and the pathogenesis of MS as a chronic autoimmune and inflammatory disease. …”
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Attachment as a factor in generating satisfaction with, and loyalty to, rural tourism destinations by Ana María Campón-Cerro, Helena Maria Baptista Alves, José Manuel Hernández-Mogollón

“…In addition, this field lacks causal studies related to marketing, to better plan, manage and commercialise these destinations and their companies. …”
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Factors affecting community participation in the waste bank in sukoharjo regency: Implications for circular economy by Dara Sari Lusia, Marwanti Sri, Barokah Umi

“…This research used binary logistic regression analysis and causal loop diagram (CLD) modeling. The results indicate that the variables of knowledge and socialization related to waste significantly affect community participation. …”
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Dynamic Interactions of Urban Land Use Efficiency, Industrial Structure, and Carbon Emissions Intensity in Chinese Cities: A Panel Vector Autoregression (PVAR) Approach by Guihong Yang, Xuxi Wang, Li Peng, Xinyue Zhang

“…A PVAR model was established to analyze the long-term and short-term dynamic and causal relationships among the three variables. ULUE, IS, and CEI showed an upward trend, but significant spatial heterogeneity existed. …”
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Pathophysiological mechanisms, multidimensional diagnostics and modern therapies of pruritus in pancreatic cancer: review and perspectives by Jagienka Agata Włodyka, Urszula Zelik, Maria Przygoda, Wiktoria Domino, Gabriela Trestka, Sabina Adamczyk, Kamila Stępień, Joanna Śnieżna, Wojciech Florczak, Karol Dzwonnik, Jakub Dziewic

“…Lastly, a comprehensive therapeutic approach is addressed, consisting of causal treatment, pharmacological interventions, and supportive care. …”
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Contract Cheating ‘Pseudepigraphy’. A Cardinal Sin in Higher Education? A Phenomenological Narrative of Andragogical Experiences, Insights and Reflections by Reuben Agbelengor Glover, Cyril Senyo Kpodo, Selasi Awusi Sosu

“…Using an interpretive phenomenological analysis (IPA) in a qualitative narrative paradigm, the study discussed the critical causal factors, strategic interventions, andragogy, heutagogy, support mechanisms and software employed to mitigate graduate students’ indulgence in contract cheating in their final year thesis, dissertations, and project works/reports. …”
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Compilation a Model of Professional Competencies of Educational Managers of Iran Program and Budget Organization by Zeynab Nazarzadeh Danak, Amirhossein Mahmoodi, Abbas Khorshidi

“…Results: The outcomes reveal that the principal dimensions of professional competencies among educational managers in the Iran program and budget organization encompass six dimensions: causal conditions, contextual conditions, intervening conditions, strategies, consequences, and central categories. …”
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Body Mass Index mediates the relationship between estimated glucose disposal rate and gallstones by Shuaipeng Yuan, Yuexia Lu, Zhun Xiao, Suping Ma

“…Logistic regression, subgroup analysis, smoothed curve fitting, and causal mediation studies were among the statistical techniques used to examine the participant data. …”
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A mechanism-informed deep neural network enables prioritization of regulators that drive cell state transitions by Xi Xi, Jiaqi Li, Jinmeng Jia, Qiuchen Meng, Chen Li, Xiaowo Wang, Lei Wei, Xuegong Zhang

“…Some regulators reveal potential new therapeutic targets, drug repurposing possibilities, and putative causal single nucleotide polymorphisms. This method to analyze single-cell multi-omics data demonstrates how the interpretable design of neural networks can better decode biological systems.…”
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The Effect of Creating a Sense of Individual and Collective Psychological Ownership of the Brand in Online Communities on Buying Behavior and Online Word-of-Mouth Advertising by Yazdan Shirmohammadi, Jahan Rajabi

“…We used a structural equation modelling method to determine the causal relationship between the variables.Findings: The results showed that self-efficacy, responsibility, belonging, personal identity, and collective psychological ownership positively and significantly affect members' participation goals. …”
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Providing a Model for Developing the Entrepreneurial Capacity of the Young Generation of the Country in the Context of Curriculum Planning of the University by Somayeh Gharagozloo, Faezeh Nateghi, Mahnaz Jalalvandi

“…Similar to the elimination and final cases, which included 100 components in the form of 12 factors were extracted in the causal conditions of factors such as creativity and innovation, leadership, entrepreneurial experience and training, as well as in the intervention of five factors of teamwork, perseverance, risk-taking, independence and positive thinking. …”
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Historical Case of Cervical Penetrating Wound: From First Aid to Surgical Intervention by Koné Fatogoma Issa, Keïta Mohamed Amadou, Soumahoro Siaka, Konaté N’faly, Diarra Kassim, Timbo Samba Karim

“…The outcome was good, allowing the exit 10 days after cervicotomy. Conclusion. The causal circumstances of cervical penetrating wounds are diverse. …”
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