Influence of immune cells and inflammatory factors on Alzheimer’s disease axis: evidence from mediation Mendelian randomization study by Linzhu, Jianxin Zhang, Wenhui Fan, Chen Su, Zhi Jin

“…Results The study findings suggest potential causal relationships between six different types of immune cells and AD, as well as causal relationships between 13 immune cells and inflammatory factors. …”
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Estimating the Effect of Adhering to the Recommendations of the 2019 Canada’s Food Guide on Health Outcomes in Older Adults: Protocol for a Target Trial Emulation by Didier Brassard, Nancy Presse, Stéphanie Chevalier

“…NuAge includes 4 yearly measurements of dietary intakes, covariates, and outcomes. The per-protocol causal contrast will be the primary causal contrast of interest to account for nonadherence. …”
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Exploring genetic associations and drug targets for mitochondrial proteins and schizophrenia risk by Wenxi Sun, Ping Sun, Jin Li, Qun Yang, Qing Tian, Shiting Yuan, Xueying Zhang, Peng Chen, Chuanwei Li, Xiaobin Zhang

“…Abstract Numerous observational studies have highlighted associations between mitochondrial dysfunction and schizophrenia (SCZ), yet the causal relationship remains elusive. This study aims to elucidate the causal link between mitochondria-associated proteins and SCZ. …”
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Analysis of the spatial pattern and causes of ecological environmental quality in Myanmar based on the RSEI model and the Geodetector-GCCM method by Shuangfu Shi, Shuangfu Shi, Shuangyun Peng, Shuangyun Peng, Zhiqiang Lin, Zhiqiang Lin, Bangmei Huang, Dongling Ma, Dongling Ma, Ziyi Zhu, Ziyi Zhu, Yilin Zhu, Yilin Zhu, Rui Zhang, Ting Li

“…However, there remains limited understanding of the interactions and causal relationships between multiple factors, with existing studies mainly focusing on the impact of individual factors on EEQ and their correlations. …”
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Lipid Profiles, Telomere Length, and the Risk of Malignant Tumors: A Mendelian Randomization and Mediation Analysis by Shupeng Liu, Zhengzheng Fu, Hui Liu, Yinghui Wang, Meijuan Zhou, Zhenhua Ding, Zhijun Feng

“…TL showed positive causal associations with lung and hematologic cancers (OR > 1, <i>p</i> < 0.05). …”
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Association between wide-ranging food intake and Parkinson’s disease: a comprehensive mendelian randomization study by Yana Su, Yulei Hao, Wanhui Dong, Ruqing Qiu, Ying Zhang

“…Our study reveals the causal relationships between Pancake intake, and Mozzarella intake with Parkinson’s disease.…”
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Estimating the contribution of Arctic sea-ice loss to central Asia temperature anomalies: the case of winter 2020/2021 by Lara R Cosford, Rohit Ghosh, Marlene Kretschmer, Clare Oatley, Theodore G Shepherd

“…This lagged relationship was observed in 2020/2021. Using a causal network framework grounded in known physical mechanisms, we assess how strongly one factor directly influences another (i.e. the causal relationship) and apply this analysis to the anomalies from 2020/2021. …”
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A genetic exploration of the relationship between posttraumatic stress disorder and cardiovascular diseases by Eva Lukas, Rada R. Veeneman, Dirk J. A. Smit, Tarunveer S. Ahluwalia, Jentien M. Vermeulen, Gita A. Pathak, Renato Polimanti, Karin J. H. Verweij, Jorien L. Treur

“…While insomnia, smoking, alcohol, and inflammation were important mediators, independent causal effects also remained. In addition to shared genetic liability between PTSD and CVD, we present strong evidence for causal effects of PTSD on CVD. …”
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The association between serum albumin levels and metabolic syndrome based on the NHANES and two sample Mendelian randomization study by Yile Tang, Yong Fan, Jin Su, Zisen Yang, Zaoling Liu

“…However, it is unclear whether this association is causal or only influenced by confounding factors, so further investigation is needed to determine the causal relationships. …”
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Assessing the relationship between wrist synovitis and anxiety: a study using clinical statistics and Mendelian randomization analysis by Xunhao Wang, Linyi Zhu, Jingyi Mi, Fei Xiong

“…Although arthroscopic synovectomy can alleviate physical symptoms, whether it also improves anxiety and the causal relationship between synovitis and anxiety remains unclear. …”
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Genetic insights into the risk of hip osteoarthritis on stroke: A single-variable and multivariable Mendelian randomization. by Zhengze Zhang, Yanan Lian, Yuewen He, Hao Liu, Kai Meng, Yong Wang, Wuhua Ma

“…This study aims to further elucidate the causal relationship between the two, employing Two-Sample and Multivariable Mendelian randomization methods.…”
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Genetic association between immune-mediated inflammatory diseases and peripheral artery disease: a Mendelian randomization study by Haichao Wu, Dandan Zheng, Long Zhou, Qiang Wang, Tao Wang, Siyuan Liang

“…Our analysis supported the causal association of RA with increased risks of PAD. …”
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Towards a global knowledge for environmentally sustainable development agenda in 21 st century southern Africa by Stanford Garikayi Mukasa

“…Is there a missing link, variable or factor in all of these attempts to causally relate information and communication to development? …”
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Association of Myasthenia Gravis With Autoimmune Thyroid Disease: A Bidirectional Mendelian Randomization Study by Yao Wang, Ke Wang, Jing Lu, Peng Xu, Dongmei Zhang, Xinzhi Chen, Jian Wang

“…The primary method for evaluating causal effects was the inverse variance weighted (IVW) method. …”
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Space time manifolds and contact structures by K. L. Duggal

“…We show that odd dimensional strongly causal (in particular, globally hyperbolic) spacetimes can carry a regular contact structure. …”
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Natural Experiments in Labor Economics and Beyond by Simon Jäger, Jörn-Steffen Pischke

“…Abstract This year’s Nobel Prize in Economics honoured David Card of the University of California, Berkeley “for his empirical contributions to labour economics”, and Joshua Angrist of MIT and Guido Imbens of Stanford University “for their methodological contributions to the analysis of causal relationships”. We explain how the laureates revolutionised the analysis of causal relationships in empirical economics through the methodology of natural experiments. …”
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Using fuzzy clustering to reconstruct alert correlation graph of intrusion detection by MA Lin-ru1, YANG Lin2, WANG Jian-xin2, TANG Xin2

“…Causal correlation method was one of the most representative methods for instruction detection alert correla-tion. …”
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Genetic associations of plasma metabolites with immune cells in hyperthyroidism revealed by Mendelian randomization and GWAS-sc-eQTLs xQTLbiolinks analysis by Yutong Li, Xingyu Song, Yuyang Huang, Sifan Zhou, Linkun Zhong

“…Abstract Mendelian randomization (MR) was employed to investigate the causal relationships between immune cell phenotypes, hyperthyroidism (HD), and potential metabolic mediators. …”
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Inflammatory bowel disease increases the risk of pancreatitis: a two-sample bidirectional Mendelian randomization analysis by Li-Hui Fang, Jia-Qi Zhang, Jin-Ke Huang, Xu-Dong Tang

“…However, there is no causal relationship between AP and the risk of UC, and there is no causal relationship between CP and the risk of IBD and its subtypes(P > 0.05). …”
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Desheredación e indignidad: hacia una inclusión de los concubinos en el derecho sucesorio peruano by Santiago Herrera Navarro

“… Este artículo analiza las implicaciones legales de los concubinatos en la asignación de herencias en la legislación peruana, destacando la necesidad de reformar las causales de exclusión, como la desheredación y la indignidad, para incluir a los concubinos. …”
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