O perspectivă inedită asupra romanului latin by Carmen-Nicola Jumara

“…Drawing a distinction between the story and the intrigue, we underline that the first one is a narration of some events, especially based upon curiosity, while the intrigue is also a narration, but it implies also intelligence and good memory, the stress being focused on causality. We can discuss about intrigue in the two Latin novels because every deed, every word matters there, everything is economical and has an organic meaning, even if it is complicated. …”
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Expression of cell-wall related genes is highly variable and correlates with sepal morphology by Hartasánchez, Diego A., Kiss, Annamaria, Battu, Virginie, Soraru, Charline, Delgado-Vaquera, Abigail, Massinon, Florian, Brasó-Vives, Marina, Mollier, Corentin, Martin-Magniette, Marie-Laure, Boudaoud, Arezki, Monéger, Françoise

“…Overall, our work highlights the benefit of using coupled variation in gene expression and phenotype in wild-type plants to shed light on the mechanisms underlying organ size and shape determination. Although causality between gene expression and sepal morphology has not been established, our approach opens the way to informed analysis for mutant characterization and functional studies. …”
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Point-of-care tests in the emergency medical services: a scoping review by T. H. M. Moore, S. Dawson, K. Kirby, R. Body, A. Thompson, Y. O. Adepoju, R. Perry, H. Nicholson, J. Dinnes, K. Mitchell, J. Savović, S. Voss, J. R. Benger

“…Few studies were of a design to inform guidelines to change patient pathways and the associated outcomes, including, randomised controlled trials (RCTs) (4%), non-randomised studies able to assess causality (6%), economic analyses (1%) or qualitative work on acceptability (3%). …”
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Gut microbiota influence on lung cancer risk through blood metabolite mediation: from a comprehensive Mendelian randomization analysis and genetic analysis by Yizhao Du, Qin Wang, Zongmei Zheng, Hailun Zhou, Yang Han, Ao Qi, Lijing Jiao, Lijing Jiao, Yabin Gong

“…BackgroundGut microbiota (GM) and metabolic alterations play pivotal roles in lung cancer (LC) development and host genetic variations are known to contribute to LC susceptibility by modulating the GM. However, the causal links among GM, metabolite, host genes, and LC remain to be fully delineated.MethodThrough bidirectional MR analyses, we examined the causal links between GM and LC, and utilized two-step mediation analysis to identify potential mediating blood metabolite. …”
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Gut microbiota and blood biomarkers in IBD-Related arthritis: insights from mendelian randomization by Wei Yang, Miao Cui, Peng Yang, Chenlin Liu, Xiuzhen Han, Wenyi Yao, Zhenhua Li

“…Lastly, in the reverse MR study, the insufficient number of SNPs available for analysis precluded the detection of a reverse causal relationship. This study employs the MR method to elucidate the potential causal relationships among gut microbiota, plasma proteins, inflammatory proteins, and blood and urine biomarkers in relation to the occurrence and progression of IBD-related arthritis. …”
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Dealing with Complexity – Knowledge, design, and management of the built environment by Cesare Sposito, Francesca Scalisi

“…In this view, ‘complex’ should be brought back to its etymological meaning of ‘woven’ or ‘held together’, connecting different forms of knowledge in the virtuous circle of a body of knowledge articulated in a systemic view of the real world based on the principle of ‘co-evolution’ of social and ecological systems (of culture and nature) and the awareness that it determines; on the one hand, the interweaving of multiple causal chains (e.g., although the pandemic crisis is a health crisis it has also become a biological, ecological, economic, social, cultural and spiritual crisis) with interdependent effects, and on the other hand, effects that also retroact on causes since causality is circular. …”
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The fungal microbiota modulate neonatal oxygen-induced lung injury by Isaac Martin, Mary Silverberg, Ahmed Abdelgawad, Kosuke Tanaka, Brian A. Halloran, Teodora Nicola, Erin D. Myers, Jay P. Desai, Catrina T. White, Ibrahim Karabayir, Oguz Akbilgic, Laura Tipton, Samuel J. Gentle, Namasivayam Ambalavanan, Brian M. Peters, Luan D. Vu, Viral G. Jain, Charitharth V. Lal, Stephania A. Cormier, Joseph F. Pierre, Tamás Jilling, Ajay J. Talati, Kent A. Willis

“…Conclusions These findings demonstrate that features of the initial intestinal fungal microbiome are associated with the later development of BPD in premature neonates and exert a microbiome-driven effect that is transferable and modifiable in murine models, which suggests both causality and a potential therapeutic strategy. Video Abstract…”
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Laying the groundwork: Exploring pesticide exposure and genetic factors in south-eastern Brazilian farmers by Débora Dummer Meira, Victor Nogueira Da Gama Kohls, Matheus Correia Casotti, Luana Santos Louro, Gabriel Mendonça Santana, Thomas Erik Santos Louro, Adriana Madeira Alvares da Silva, Lorena Souza Castro Altoé, Raquel Reis Trabach, Sonia Groisman, Elizeu Fagundes de Carvalho, Jamila Alessandra Perini Machado, Stephanie Seneff, Iúri Drumond Louro

“…These findings suggest that the CYP2C9 genotype may influence the way farmers exposed to pesticides respond, but more research is needed to clarify causality and investigate other possible health effects. …”
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Assessing the relationships of 1,400 blood metabolites with abdominal aortic aneurysm: a Mendelian randomization study by Qian Guo, Xinghua Xu, Xiaohui Li, Yang Mao, Shengqiang Li, Yuxin Yao, Xiang Li, Yaxing Li, Jiayue Feng, Yan Shu, Xingli Xu

“…However, evidence of a causal relationship between blood metabolites and AAA is still lacking at present.MethodsUsing Mendelian randomization (MR), we assessed the causal association between 1,400 serum metabolites and AAA. …”
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The Mechanical Power in Patients with Acute Respiratory Distress Syndrome Undergoing Prone Positioning Can Predict Mortality by Ko-Wei Chang, Shaw-Woei Leu, Han-Chung Hu, Ming-Cheng Chan, Shinn-Jye Liang, Kuang-Yao Yang, Li-Chung Chiu, Wen-Feng Fang, Chau-Chyun Sheu, Ying-Chun Chien, Chung-Kan Peng, Ching-Tzu Huang, Kuo-Chin Kao

“…Further randomized controlled research is required to elucidate the potential causality of decreased MP and improved clinical outcomes.…”
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Exploring the mechanisms of Devonian oceanic anoxia: impact of ocean dynamics, palaeogeography, and orbital forcing by J. Gérard, L. Sablon, J. J. C. Huygh, A.-C. Da Silva, A. Pohl, C. Vérard, M. Crucifix

“…While growing geological evidence has demonstrated a temporal correlation between astronomical forcing and anoxia during this period, underlying physical mechanisms remain unknown, hence questioning causality. Here, we perform multiple sensitivity experiments, using an Earth system model of intermediate complexity (cGENIE), to isolate the influences of specific Devonian climate and palaeogeography components on ocean oxygen levels, contributing to the better understanding of the intricate interplay of factors preconditioning the ocean to anoxia. …”
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Presenting the local model of increasing the market share in Iran's dairy industry with a qualitative approach by leila taheri fard, farzad asayesh, alireza rousta

“…How these factors affect market share in the form of structure, behavior and performance patterns has always been a subject of disagreement among industrial economists, so that the economists of the school of structuralism consider the direction of causality from structure to function; while behaviorists and economists of the Chicago school consider the direction of causality from performance to behavior and structure (Abzari, Safari Shad, Abedi Sharbiani & Porveshi Murad, 2019). …”
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Spare Parts Inventory Optimization for Military Vehicles Using a Mixed Probability Distribution by Mojtaba Salehi, Mojtaba Omidvar, Shohreh Shariati

“…Research limitations: This research was conducted on a case-by-case basis on the parts of military vehicles of the 177th brigade of Torbat Heydarieh city, so it should be possible to generalize it to other organizations, and because it was typically a cross-sectional study, conclusions about on the causality might seem difficult. Practical implications: The main challenge in the supply chain is to control inventory levels by determining the size of orders for each department during each period to optimize the objective function, which has been investigated in various studies because inventory optimization is one of the important and practical techniques for optimizing the economic value of the order and realizing a stable situation in a production system. …”
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Association between non-insulin-based insulin resistance indicators and frailty progression: a national cohort study and mendelian randomization analysis by Hui Tian, Yong-meng Li, Cheng-qiang Wang, Guo-qiang Chen, Ying Lian

“…Findings from MR analysis showed a causal relationship between higher TyG index and increased risk of frailty (β = 0.214, 95% CI = 0.079, 0.349; P = 0.002). …”
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Analyzing Expressions of the Design Argument and Answering Doubts Attributed to it Based on the Type of Logical Reasoning by Shokoh Monazzam, Abbas Abbaszadeh, Naser Forouhi

“…Therefore, real believers would not conclude the existence of a contriver creature in the design argument based on knowing the world as a mechanical one but perceive an intelligent cause based on definite and obvious rules like causality and cause-effect suitability.…”
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Genetic factors shaping the plasma lipidome and the relations to cardiometabolic risk in children and adolescentsResearch in context by Yun Huang, Sara Elizabeth Stinson, Malte Thodberg, Louise Aas Holm, Roman Thielemann, Karolina Sulek, Morten Asp Vonsild Lund, Cilius Esmann Fonvig, Min Kim, Kajetan Trost, Helene Bæk Juel, Trine Nielsen, Peter Rossing, Maja Thiele, Aleksander Krag, Cristina Legido-Quigley, Jens-Christian Holm, Torben Hansen

“…Colocalisation and Mendelian randomisation (MR) analyses were performed to infer causality between lipid species and cardiometabolic outcomes. …”
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Cardio-metabolic-related plasma proteins reveal biological links between cardiovascular diseases and fragility fractures: a cohort and Mendelian randomisation investigationResearch... by Karl Michaëlsson, Rui Zheng, John A. Baron, Tove Fall, Alicja Wolk, Lars Lind, Jonas Höijer, Carl Brunius, Eva Warensjö Lemming, Olga E. Titova, Bodil Svennblad, Susanna C. Larsson, Shuai Yuan, Håkan Melhus, Liisa Byberg, Hannah L. Brooke

“…Mendelian randomisation (MR) analysis supported causality since genetically predicted levels of SOST (Sclerostin), CCDC80 (Coiled-coil domain-containing protein 80), NT-proBNP (N-terminal prohormone brain natriuretic peptide), and BNP (Brain natriuretic peptide) were associated with risk of hip fracture. …”
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Citizen science platforms can effectively support early detection of invasive alien species according to species traits by Pablo González‐Moreno, Ana A. Anđelković, Tim Adriaens, Christophe Botella, Jakovos Demetriou, Rita Bastos, Sandro Bertolino, Celia López‐Cañizares, Franz Essl, Živa Fišer, Milka Glavendekić, Marc Herremans, Philip E. Hulme, Viola Jani, Dimitra Katsada, Periklis Kleitou, Nicola La Porta, Katharina Lapin, Marta López‐Darias, Vanessa Lozano, Angeliki F. Martinou, Damiano Oldoni, Esra Per, Stephanie Rorke, Helen E. Roy, Karl‐Manfred Schweinzer, Kristijn Swinnen, Elena Tricarico, Joana R. Vicente, Maarten de Groot, Michael J. O. Pocock

“…Although we cannot determine causality (the first official record could have been from a citizen science platform, or contemporaneous with it), this demonstrates that citizen science platforms are effective for IAS early detection. …”
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The role of teachers and administrators in supporting the adaptation of students with special needs in mainstream high schools by Amir Mahmood, Xiao Huang, Nadia Rehman

“…Second, the study’s cross-sectional design limits the ability to establish causality between the variables. Longitudinal studies would be beneficial in exploring the causal relationships between teacher and administrative support and students’ adaptation capabilities. …”
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Inflammatory rheumatic diseases with onset after SARS-CoV-2 infection or COVID-19 vaccination: a report of 267 cases from the COVID-19 and ASD group by Laura Massaro, Annamaria Iagnocco, Florenzo Iannone, Corrado Campochiaro, Maria De Santis, Ilaria Cavazzana, Piero Ruscitti, Roberto Giacomelli, Rosario Foti, Lorenzo Dagna, Giovanna Cuomo, Giacomo De Luca, Francesco Caso, Ilenia Di Cola, Clodoveo Ferri, Vincenzo Raimondo, Francesco Ursini, Veronica Brusi, Giuseppe Varcasia, Roberta Pellegrini, Domenico Olivo, Giuseppe Murdaca, Carlo Selmi, Olga Addimanda, Erika Pigatto, Francesca Francioso, Rossella De Angelis, Jacopo Ciaffi, Luana Mancarella, Marcella Visentini, Francesca Motta, Virginia Caira, Alberto Lo Gullo, Caterina Naclerio, Elena Marchetti, Sebastiano Lorusso, Jessica Luppino, Roberta Foti, Massimo Reta

“…Despite the short follow-up period, IJD and PMR patients’ response to first-line therapy was favourable, with both groups achieving a drop in baseline disease activity scores of ~30% and ~70% respectively.Conclusion Our article reports the largest cohort published to date of new-onset IRD following SARS-CoV-2 infection or COVID-19 vaccines. Although causality cannot be ascertained, the spectrum of possible clinical manifestations is broad and includes IJD, PMR, CTD and vasculitis.…”
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