Ethical dilemmas in the care of patients suffering from psychotic catatonia: a case report by Luigi F. Saccaro, Luigi F. Saccaro, Barbara Privé, Ambra D’Imperio, Ambra D’Imperio, Claire Bridel, Othman Sentissi, Othman Sentissi, Alexandre Wullschleger

“…Ethical debates focus on respecting autonomy, minimizing damaging effects, and acting in the patient’s best interest.CaseWe present a unique case of a young patient suffering from a first episode of catatonic psychosis, in which striking this balance was especially difficult given the patient’s complete mutism and opposition, given the absence of immediate danger to herself or others, the lack of anamnestic information, and her avoidance of social support, which would have meant that she would not have encountered psychiatric care, were it not for an exceptional government plan in place at the time of hospitalization. …”
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Expression of catecholaminergic genes in the midbrain and prepulse inhibition in rats with a genetic catatonia by M. A. Ryazanova, O. I. Prokudina, V. S.  Plekanchuk, T. A. Alekhina

“…The GC rat strain (from the words “genetic” and “catatonia”) was created by selection for predisposition to passive-defensive reaction of catatonic freezing in response to stressing stimuli. …”
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X-Linked Autism Type 9 Caused by a Hemizygote Pathogenic Variant in the TMLHE Gene: Etiological Diagnosis in an Adult Male with Moderate Intellectual Disability by Verhoeven WM, Pfundt R, Engelke UF, Kluijtmans LA, Egger JI

“…Also, Whole Exome Sequencing (WES) and Next-Generation Metabolic Screening (NGMS) were performed.Results: Moderate intellectual disability along with obsessive and aggressive behaviour in the context of autism spectrum disorders was established as well as symptoms from the catatonic spectrum. With WES, a novel variant in the TMHLE gene was identified and using NGMS, increased concentration of trimethyllysine and decreased concentration of γ-butyrobetaine were found resulting in a significantly decreased BB/TML ratio, confirming the pathogenicity of this variant.Conclusion: X-linked autism type 6 is characterized by moderate intellectual disability and symptoms from the autism spectrum in the absence of any dysmorphisms. …”
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Alternative psychopharmacologic treatments for pediatric catatonia: a retrospective analysis by Joshua R. Smith, Joshua R. Smith, Isaac Baldwin, Tasia York, Carina Anderson, Trey McGonigle, Simon Vandekar, Lee Wachtel, James Luccarelli, James Luccarelli

“…. = 43.2, p < 0.001, 95% CI = (0.931,0.992)], indicating the average subject is expected to experience some improvement.DiscussionIn conclusion, all patients responded to these treatments with improvement in their catatonic symptoms. Alternative pharmacologic interventions for catatonia, including benzodiazepines other than lorazepam, valproic acid, NMDA receptor antagonists, and atypical antipsychotics were safe and effective in treating catatonia in this population.…”
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