Meta-Analysis and Evidence Base for the Efficacy of Autologous Bone Marrow Mesenchymal Stem Cells in Knee Cartilage Repair: Methodological Guidelines and Quality Assessment by Mohamed E. Awad, Khaled A. Hussein, Inas Helwa, Mohamed F. Abdelsamid, Alexandra Aguilar-Perez, Ibrahim Mohsen, Monte Hunter, Mark W. Hamrick, Carlos M. Isales, Mohammed Elsalanty, William D. Hill, Sadanand Fulzele

“…The aim of this study is to review all the published clinical trials on autologous bone marrow mesenchymal stem cells (BM-MSCs) in the repair of cartilage lesions of the knee. We performed a comprehensive search in three electronic databases: PubMed, Medline via Ovid, and Web of Science. …”
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Corrigendum to “Poly(ε-caprolactone)/Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Blend from Fused Deposition Modeling as Potential Cartilage Scaffolds” by Wasana Kosorn, Pacharapan Sonthithai, Wanida Janvikul, Patcharaporn Wutticharoenmongkol

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Physicobiochemical Characteristics and Chondrogenic Differentiation of Bone Marrow Mesenchymal Stem Cells (hBM-MSCs) in Biodegradable Porous Sponge Bovine Cartilage Scaffold by Dwikora Novembri Utomo, Ferdiansyah Mahyudin, Teddy Heri Wardhana, Purwati Purwati, Febrian Brahmana, Agrippina Waya Rahmaning Gusti

“…Tissue engineering had been believed to overcome the limitation of cartilage lesions treatment. Nowadays the studies focus on using mesenchymal stem cells in scaffold. …”
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Neuronal guidance factor Sema3A inhibits neurite ingrowth and prevents chondrocyte hypertrophy in the degeneration of knee cartilage in mice, monkeys and humans by Shishu Huang, Dashuang Gao, Zhenxia Li, Hongchen He, Xi Yu, Xuanhe You, Diwei Wu, Ze Du, Jiancheng Zeng, Xiaojun Shi, Qinshen Hu, Yong Nie, Zhong Zhang, Zeyu Luo, Duan Wang, Zhihe Zhao, Lingli Li, Guanglin Wang, Liping Wang, Zongke Zhou, Di Chen, Fan Yang

“…Abstract Osteoarthritis (OA) is a degenerative joint disease accompanied with the loss of cartilage and consequent nociceptive symptoms. Normal articular cartilage maintains at aneural state. …”
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A large giant cell tumor of the larynx: case report and review of the literature by Andrew Arndt, Rachelle LeBlanc, Peter Spafford

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Vibroarthrography as a Noninvasive Screening Method for Early Diagnosis of Knee Osteoarthritis: A Review of Current Research by Robert Karpiński, Aleksandra Prus, Kamil Jonak, Przemysław Krakowski

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Cricoid chondroma presenting as upper airway obstruction: A report of a rare case by Samuel Sisay Hailu, MD, Eyoel Degafu, MD, Tequam Debebe, MD, Yonas Shumiye, MD, Bizunesh Dires, MD, Bethlehem Tesfasilassie Kibrom, MD

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Local delivery of TGF-β1-mRNA decreases fibrosis in osteochondral defects by Gianluca Fontana, Brett Nemke, Yan Lu, Connie Chamberlain, Jae-Sung Lee, Joshua A. Choe, Hongli Jiao, Michael Nelson, Margot Amitrano, Wan-Ju Li, Mark Markel, William L. Murphy

Subjects: “…Cartilage…”
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Arctiin alleviates knee osteoarthritis by suppressing chondrocyte oxidative stress induced by accumulated iron via AKT/NRF2/HO-1 signaling pathway by Junzheng Yang, Delong Chen, Qi He, Baihao Chen, Zhaofeng Pan, Gangyu Zhang, Miao Li, Shaocong Li, Jiacong Xiao, Haibin Wang, Peng Chen, Zhantian An

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Polydatin retards the progression of osteoarthritis by maintaining bone metabolicbalance and inhibiting macrophage polarization by Qi Sun, Xin-Yu Nan, Hui Wang, Shuo Pan, Gang Ji, Ya-Feng Guo, Ya-Heng Zhao, Gao-Cen Li, Shao-Shi Guo, Lu-Feng Lin, Yu-Jie Jin, Xue Li Zhang, Chang-Cheng Liu, Guo-Bin Liu

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Leptin Enhances Synthesis of Proinflammatory Mediators in Human Osteoarthritic Cartilage—Mediator Role of NO in Leptin-Induced PGE2, IL-6, and IL-8 Production by Katriina Vuolteenaho, Anna Koskinen, Meiju Kukkonen, Riina Nieminen, Unto Päivärinta, Teemu Moilanen, Eeva Moilanen

“…In the present paper, the effects of leptin on human OA cartilage were studied. Leptin alone or in combination with IL-1 enhanced the expression of iNOS and COX-2, and production of NO, PGE2, IL-6, and IL-8. …”
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miR-223 promotes cartilage differentiation of bone marrow-derived mesenchymal stem cells and protects against osteoarthritis by suppressing NLRP-3 expression by Nan Min, Jie Ma, Lei Shi, Lin Wang, Chi Liu, Yaonan Zhang, Qingyun Xue

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Retaining Severely Damaged Talar Body and Medial Malleolar Cartilage for Diabetic Ankle/Hindfoot Charcot Arthrodesis Using Intramedullary Nail: A Short Report by Kaissar Yammine MD, PhD, Camille Samaha MD, Chahine Assi MD, MSc

“…The talus was retained after excision of its proximal and distal cartilages while the medial malleolus cartilage was not touched. …”
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Comparison of Concentration- and Homology-Dependent Effects of the Proinflammatory Cytokine Interleukin-1β (IL-1β) in a Bovine Chondrocyte Inflammation Model by Robert Ossendorff, Sarah Kurth, Su Wang, Max Jaenisch, Elio Assaf, Sebastian Scheidt, Kristian Welle, Christof Burger, Dieter C. Wirtz, Andreas C. Strauss, Frank A. Schildberg

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Multicystic renal dysplasia, a histomorphological spectrum: Seven years experience from a tertiary care hospital by Kanika Gupta, Shramana Mandal, Varuna Mallya, Meeta Singh, Nita Khurana, Yogesh K. Sarin

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Discoidin domain receptors; an ancient family of collagen receptors has major roles in bone development, regeneration and metabolism by Renny T. Franceschi, Shawn A. Hallett, Chunxi Ge

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Experimental Study of Modified Videman Method to Replicate Knee Osteoarthritis in Rabbits by Jing LIU, Qiaoxuan LIN, Liming LU, Zexing GUO, Hong LIU, Liangzhi ZHANG, Zhongbiao XIU

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Mesenchymal stem cells for osteoarthritis: Recent advances in related cell therapy by Jianjing Lin, Jingtao Huang, Zilu Jiao, Mengyuan Nian, Canfeng Li, Yali Dai, Shicheng Jia, Xintao Zhang

Subjects: “…cartilage…”
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Effect of older age and/or ACL injury on the dose–response relationship between ambulatory load magnitude and immediate load-induced change in serum cartilage oligomeric matrix protein by Simon Herger, Corina Nüesch, Anna-Maria Liphardt, Christian Egloff, Annegret Mündermann

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Extracellular Vesicles Derived from Human Umbilical Mesenchymal Stem Cells Transfected with miR-7704 Improved Damaged Cartilage and Reduced Matrix Metallopeptidase 13 by Kun-Chi Wu, Hui-I Yang, Yu-Hsun Chang, Raymond Yuh-Shyan Chiang, Dah-Ching Ding

“…Walking capacity (rotarod test), cartilage morphology, histological scores, and the expression of type II collagen, aggrecan, interleukin-1 beta, and matrix metalloproteinase 13 (MMP13) in the cartilage were evaluated. …”
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