3D Electrospun Nanofiber-Based Scaffolds: From Preparations and Properties to Tissue Regeneration Applications by Shanshan Han, Kexin Nie, Jingchao Li, Qingqing Sun, Xiaofeng Wang, Xiaomeng Li, Qian Li

“…The applications of 3D ENF-S in cartilage, bone, tendon, ligament, skeletal muscle, nerve, and cardiac tissue regeneration are then presented with a discussion of current challenges and future directions. …”
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Long-term outcomes after fixation of pure chondral fragment from the femoral trochlea in adolescents –three case reports- by Shuto Yamashita, Ryohei Uchida, Tomohiko Matsuo, Norimasa Nakamura, Shuji Horibe, Yukiyoshi Toritsuka

“…Radiographs showed no osteoarthritic changes and MRI showed good integration with the surrounding native cartilage and smooth surface in all cases. In all cases, Lysholm score and IKDC score were over 95, and most of KOOS were over 90. …”
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Injectable Self-Assembling Procyanidin Nanospheres for Effective Osteoarthritis Treatment by Li G, He F, Feng J, Xu G, Wu C, Qiao Y, Liu Y, Chen H, Du P, Wang J

“…In an enzymolysis model of rat OA, PAs/PF127 nanospheres significantly reduce joint space swelling in the early stages of cartilage destruction and accelerate the formation of subchondral bone and cartilaginous surface.Implication: This study offers valuable insights into the preparation of novel PA nanospheres for effective repair of OA.Keywords: procyanidin, self-assembling nanospheres, injectable, osteoarthritis treatment…”
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Histological and Immunohistochemical Evaluation of Autologous Cultured Bone Marrow Mesenchymal Stem Cells and Bone Marrow Mononucleated Cells in Collagenase-Induced Tendinitis of E... by Antonio Crovace, Luca Lacitignola, Giacomo Rossi, Edda Francioso

“…In cBMSC- and BMMNCS-treated tendons, a high expression of cartilage oligomeric matrix protein (COMP) and type I collagen, but low levels of type III collagen were revealed by immunohistochemistry, with a normal longitudinally oriented fiber pattern. …”
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Patients Walking Faster After Anterior Cruciate Ligament Reconstruction Have More Gait Asymmetry by Rachel J. Knobel, Naoaki Ito, Elanna K. Arhos, Jacob J. Capin, Thomas S. Buchanan, Lynn Snyder-Mackler

“…Slower walking speeds have been associated with biomarkers suggesting cartilage breakdown. The relationship between walking speed and gait symmetry after ACLR is unknown…”
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Arctiin alleviates the progression of osteoarthritis by regulating the cholesterol metabolic pathway by Jiale Mai, Jiacong Xiao, Yanhuai Ma, Dawei Gong, Jianliang Li

“…It modulated cholesterol metabolism in IL-1β-stimulated chondrocytes by inhibiting the CH25H-CYP7B1-RORα axis, reducing cartilage damage and proteoglycan loss in OA rats, and effectively inhibiting subchondral bone osteolysis. …”
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Stem Cells and Regenerative Medicine: Myth or Reality of the 21th Century by J.-F. Stoltz, N. de Isla, Y. P. Li, D. Bensoussan, L. Zhang, C. Huselstein, Y. Chen, V. Decot, J. Magdalou, N. Li, L. Reppel, Y. He

“…Different clinical applications are under study (cardiac insufficiency, atherosclerosis, stroke, bone and cartilage deterioration, diabetes, urology, liver, ophthalmology, and organ’s reconstruction). …”
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Open Medial Meniscus Centralization With Arthroscopic Root Repair by Nicholas Newcomb MD, Jared Sanderford MD, Tyag Patel MD, Price Sessums MD, Ryan Price MD, William Curtis MD, Gehron Treme MD, Christopher Shultz MD

“…If left untreated, these extruded tears may result in loss of medial compartment cartilage. As a result, multiple approaches have been developed to centralize the extruded meniscus. …”
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Biocompatible ionized air alleviates rat osteoarthritis by modulating polarization from M1 to M2 macrophages by Haoran Yu, Chengbiao Ding, Zhongyao Hu, Qi Liu, Xuesong Gu, Junyan He, Yiqun Yan, Shenrui Yu, Lin Gao, Wendan Cheng, Zhengwei Wu, Juehua Jing

“…In vivo studies in rats showed that BIA inhibited M1 macrophage infiltration in the synovium, upregulated the proportion of M2 macrophages, alleviated cartilage degeneration, and delayed OA progression. …”
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Production of Adult Human Synovial Fluid-Derived Mesenchymal Stem Cells in Stirred-Suspension Culture by Kristen D. Jorgenson, David A. Hart, Roman Krawetz, Arindom Sen

“…The chondrogenic potential of synovial fluid-derived mesenchymal stem cells (SF-MSCs) supports their use in cartilage regeneration strategies. However, their paucity in synovial fluid necessitates their proliferation in culture to generate clinically relevant quantities. …”
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Congenital laryngeal anomalies in childhood by Yulia E. Stepanova

“…Nine (11%) patients suffered from arytenoid cartilage dyschronia, and 7 (8%) patients suffered from dysplasia. …”
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Quadriceps and Hamstrings Activation Peaks Earlier as Athletes Repeatedly Hop, but There are Differences Depending on ACL Reconstruction Technique. by Einar Einarsson, Olivia Barbosa, Magnus Kjartan Gislason, Kristin Briem, Argyro Kotsifaki, Rodney Whiteley

“…# Background After Anterior Cruciate Ligament Reconstruction (ACLR) athletes face the challenge of regaining their previous competitive level while avoiding re-injury and early knee joint cartilage degeneration. Quadriceps and hamstrings strength reductions and neuromuscular alterations potentially related to risk of re-injury are present after ACLR and relate to deficits in muscle activation…”
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IL-1β Suppresses the Formation of Osteoclasts by Increasing OPG Production via an Autocrine Mechanism Involving Celecoxib-Related Prostaglandins in Chondrocytes by Yusuke Watanabe, Aki Namba, Yukiko Aida, Kazuhiro Honda, Hideki Tanaka, Naoto Suzuki, Hideo Matsumura, Masao Maeno

“…Elevated interleukin (IL)-1 concentrations in synovial fluid have been implicated in joint bone and cartilage destruction. Previously, we showed that IL-1β stimulated the expression of prostaglandin (PG) receptor EP4 via increased PGE2 production. …”
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A CASE REPORT: ENHANCING TARSAL AND MUSCULAR SUPPORT FOR ECTROPION CORRECTION IN TESSIER 3 AND 5 FACIAL CLEFT by Teuku Adifitrian, Hendra Tri Hartono, Agustina Indah Garnasih

“…The initial surgeries were performed to address a unilateral facial cleft classified as Tessier 3 and 5, utilizing ear cartilage grafts for the tarsal plate. However, she subsequently experienced complications, including ectropion, epiphora, and soft tissue deformities around her left eye. …”
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Safety and efficacy of mesenchymal stromal cells mitochondria transplantation as a cell-free therapy for osteoarthritis by Ana Maria Vega-Letter, Cynthia García-Guerrero, Liliana Yantén-Fuentes, Carolina Pradenas, Yeimi Herrera-Luna, Eliana Lara-Barba, Felipe A. Bustamante-Barrientos, Masyelly Rojas, María Jesús Araya, Nicole Jeraldo, Constanza Aros, Francisca Troncoso, Daniela Poblete, Angela Court, Alexander Ortloff, Jose Barraza, Francesca Velarde, Carlos Farkas, Claudio Carril, Noymar Luque-Campos, Gonzalo Almarza, Maximiliano Barahona, Jose Matas, Lucas Cereceda, Rocío Lorca, Jorge Toledo, Karina Oyarce, Rolando Vernal, Andrés Caicedo, Andrea del Campo, Yessia Hidalgo, Roberto Elizondo-Vega, Farida Djouad, Maroun Khoury, Fernando E. Figueroa, Patricia Luz-Crawford

“…Conclusion Collectively, our results reveal that mitochondria derived from MSC are transferred to key articular cells and are retained in the joint without generating an inflammatory immune response mitigating articular cartilage degradation in OA, probably through a restorative effect triggered by the stress antiviral response within OA chondrocytes.…”
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Clinical-grade extracellular vesicles derived from umbilical cord mesenchymal stromal cells: preclinical development and first-in-human intra-articular validation as therapeutics f... by Aliosha I. Figueroa-Valdés, Patricia Luz-Crawford, Yeimi Herrera-Luna, Nicolás Georges-Calderón, Cynthia García, Hugo E. Tobar, María Jesús Araya, José Matas, Darío Donoso-Meneses, Catalina de la Fuente, Jimena Cuenca, Eliseo Parra, Fernando Lillo, Cristóbal Varela, María Ignacia Cádiz, Rolando Vernal, Alexander Ortloff, Gino Nardocci, Verónica Castañeda, Catalina Adasme-Vidal, Maximiliano Kunze-Küllmer, Yessia Hidalgo, Francisco Espinoza, Maroun Khoury, Francisca Alcayaga-Miranda

“…Abstract Osteoarthritis (OA) is a joint disease characterized by articular cartilage degradation. Persistent low-grade inflammation defines OA pathogenesis, with crucial involvement of pro-inflammatory M1-like macrophages. …”
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The role of VNTR aggrecan gene polymorphism in the development of osteoarthritis in women by D. A. Shapovalova, A. V. Tyurin, S. S. Litvinov, E. K. Khusnutdinova, R. I. Khusainova

“…Aggrecan is one of the major structural components of cartilage and it provides the ability to resist compressive loads throughout life. …”
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Effects of gestational and lactational exposure to ethanol on body and bone growth of rat offspring by Natalia Viana Tamiasso, Fabiana Rocha Araújo, Natália de Melo Ocarino, Amanda Maria Sena Reis, Athelson Stefanon Bittencourt, Rogéria Serakides

“…The length and width of the femur and tibia and the thickness of the epiphysis were measured in the neonates, and the thickness of the articular cartilage, epiphyseal plate, and its zones were measured at 17 days of age. …”
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The effect of a barley-based food product in alleviating knee osteoarthritis discomfort symptoms in Egyptian female patients by Suzanne Fouad, Rasha Monir, Fatma A. Ibrahim, Ahmed M.S. Hussein, Heba F. Shafei, Aliaa El Gendy

“…Background/aim Osteoarthritis is a common joint condition that causes cartilage to erode. There are numerous conventional treatments available, including nonsteroidal anti-inflammatory medicines and pharmaceuticals containing glucosamine; however, taking them can result in serious side effects. …”
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Paradigms of intraoperative neuromonitoring in paediatric thyroid surgery by Yuchuan Li, Chunhai Zhang, Yi Zhang, Gianlorenzo Dionigi, Gianlorenzo Dionigi, Yishen Zhao, Hui Sun, Hui Sun, Yingying Wang

“…The use of innovative devices such as laryngeal masks with surface electrodes and thyroid cartilage receiving electrodes could replace monitoring tubes as a new form of IONM. …”
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