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321
Laryngeal recurrence sites in patients previously treated with transoral laser microsurgery for squamous cell carcinoma
Published 2018-02-01“…Final pathology reports demonstrated that 67% (10/15) of patients had thyroid cartilage involvement while 53% (9/15) of patients had cricoid cartilage involvement on salvage TL pathology. 33% (5/15) of patients had perineural invasion and 27% (4/15) had lymphovascular invasion. …”
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322
Tri-Lineage Differentiation Potential of Stem Cells from Human Exfoliated Deciduous Teeth - An In-vitro Study
Published 2024-12-01“…Material and Method: After being propagated through multiple sequential subcultures, adherent fibroblastic cells in the pulp tissue culture from human exfoliation teeth were evaluated to assess their tripotent differentiation potential into bone, cartilage, and adipose cell lineages. Result: The stem cells derived from dental pulp had a comparatively high ability for proliferation and successfully differentiated into chondrocytes and osteocytes while less significant for adipocytes. …”
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323
Macrophage Polarization in the Osteoarthritis Pathogenesis and Treatment
Published 2025-01-01“…These pathways induce low‐grade inflammation within OA‐affected joints, altering chondrocyte metabolism, inhibiting cartilage repair, and impairing mesenchymal stem cell chondrogenesis, thereby contributing to OA progression. …”
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324
Designing Novel Interfaces via Surface Functionalization of Short-Chain-Length Polyhydroxyalkanoates
Published 2019-01-01“…Thus far, these surface modifications have led to PHA being widely used in various biomedical and pharmaceutical applications such as cardiac patches, wound management, nerve, bone, and cartilage repair. This review addresses the surface modification on biomedical applications focusing on short-chain-length PHA such as poly(3-hydroxybutyrate) [P(3HB)], poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-4HB)] and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) [P(3HB-co-3HV)].…”
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325
Controversy About Management of Osteoarthritis with Disease-modifying Anti-rheumatic Drugs
Published 2025-01-01“…Osteoarthritis (OA) is a degenerative joint cartilage disease characterized pathologically by osteophytes formation and subchondral bone damage. …”
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326
Ochronotic arthropathy: skeletal manifestations and orthopaedic treatment
Published 2025-02-01“…Alkaptonuria is an extremely rare disorder of tyrosine metabolism caused by an autosomal recessive enzymatic deficiency of homogentisic acid (HGA) oxidase, causing its accumulation in collagenous structures, especially in hyaline cartilage. It is characterized by a triad of homogentisic aciduria, bluish-black discoloration of connective tissues (ochronosis) and arthropathy of the spine and large weight-bearing joints. …”
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327
Ferroptosis plays a role in osteoarthritis
Published 2024-12-01“…Furthermore, we discuss the roles of ferrioptosis in different aspects of osteoarthritis, encompassing the degradation of cartilage, synovitis, dysfunction of chondrocytes, and the manifestation of OA-related pain. …”
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328
Inhibitory effects of Spirulina in zymosan-induced arthritis in mice
Published 2002-01-01“…Histopathological and ultrastructural studies showed inhibition of the inflammatory reaction, whereas no destruction of cartilage, well-preserved chondrocytes, and normal rough endoplasmic reticulum and mitochondria were seen. …”
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329
Humeral Capitellum Fractures in Adolescents: A Study of 6 Cases Treated by Open Reduction and Internal Fixation with Bioabsorbable Nails
Published 2022-01-01“…That fractures should be anatomically reduced with no articular cartilage damage in order to prevent osteoarthritis. …”
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330
Spidroin-Based Biomaterials in Tissue Engineering: General Approaches and Potential Stem Cell Therapies
Published 2021-01-01“…., lung tissue engineering, vascularization, bone and cartilage regeneration, and peripheral nerve repair), and finally, we prospected the development direction and manufacturing technology of building more refined and customized spidroin-based protein scaffolds.…”
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331
Cartilaginous Choristoma of the Gingiva: A Rare Clinical Entity
Published 2014-01-01“…The histopathological examination revealed features of a well circumscribed mass of mature cartilage in a dense fibrous connective tissue stroma.…”
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332
Cytokine Reduction in the Treatment of Joint Conditions
Published 1994-01-01“…The destruction of joints caused by rheumatoid arthritis and osteoarthritis is characterized by an imbalance of enzyme catalysed cartilage breakdown and regeneration. A complex cytokine network perpetuates joint conditions by direct regulation of metalloproteases, by indirect recruitment of cells that secrete degradative enzymes, and by inhibition of reparative processes. …”
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333
Regeneration of Tracheal Tissue in Partial Defects Using Porcine Small Intestinal Submucosa
Published 2018-01-01“…Histological analysis revealed immature cartilage, pseudostratified ciliated epithelium, and connective tissue in 54.5% (p=0.018) of the SIS group, while no cartilaginous regeneration was observed in the control group. …”
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334
LncRNA PTS-1 Protects Against Osteoarthritis Through the miR-8085/E2F2 Axis
Published 2025-01-01“…The expression of lnc-PTS-1 was further validated by qRT-PCR in degenerated cartilage tissues, degenerative primary chondrocytes, and IL-1β-treated C28/I2 cells. …”
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335
The Impact of Body Mass Index on Osteoarthritis Severity Levels
Published 2024-12-01“…Osteoarthritis (OA) is a degenerative joint disease characterized by cartilage damage, with pain being one of the most frequent complaints among patients. …”
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336
Mesenchymal Stem Cells and Cardiovascular Disease: A Bench to Bedside Roadmap
Published 2012-01-01“…Mesenchymal progenitors, owing to their availability, ease of manipulation, and therapeutic potential, have become one of the most attractive options for the treatment of a wide range of diseases, from cartilage defects to cardiac disorders. Moreover, their immunomodulatory capacity has opened up their allogenic use, consequently broadening the possibilities for their application. …”
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337
Fat Graft Myringoplasty versus Chemical Cauterization in Small Tympanic Membrane Perforation:A Comparative Study
Published 2024-11-01“…A variety of autografts have been used for closure of tympanic membrane perforation such as perichondrium. temporalis fascia, cartilage fat, platelet rich plasma, and chemical cauterization. …”
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338
Metalloproteinase Inhibitors: Status and Scope from Marine Organisms
Published 2010-01-01“…Imbalance in the expression of MMPs leads to severe pathological condition that could initiate cardiac, cartilage, and cancer-related diseases. Three decades of endeavor for designing potent matrix metalloproteinase inhibitory substances (MMPIs) with many not making upto final clinical trials seek new resources for devising MMPIs. …”
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339
Matrix Gla Protein Binds to Fibronectin and Enhances Cell Attachment and Spreading on Fibronectin
Published 2014-01-01“…MGP is a calcification inhibitor of arteries and cartilage. However MGP is synthesized in many tissues and is especially enriched in embryonic tissues and in cancer cells. …”
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340
ATP-Dependent Chromatin Remodeling Complex in the Lineage Specification of Mesenchymal Stem Cells
Published 2020-01-01“…Mesenchymal stem cells (MSCs) present in multiple tissues can self-renew and differentiate into multiple lineages including the bone, cartilage, muscle, cardiac tissue, and connective tissue. …”
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