Bone Marrow Aspirate Concentrate-Enhanced Marrow Stimulation of Chondral Defects by Henning Madry, Liang Gao, Hermann Eichler, Patrick Orth, Magali Cucchiarini

“…A bone marrow clot forms within the cartilage defect either as a result of marrow stimulation or during the course of the spontaneous repair of osteochondral defects. …”
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Synergistic Effects of FGF-18 and TGF-β3 on the Chondrogenesis of Human Adipose-Derived Mesenchymal Stem Cells in the Pellet Culture by Liangjie Huang, Lingxian Yi, Chunli Zhang, Ying He, Liangliang Zhou, Yan Liu, Long Qian, Shuxun Hou, Tujun Weng

“…Cell-based therapy serves as an effective way for cartilage repair. Compared with a limited source of autologous chondrocytes, adipose-derived stem cells (ADSCs) are proposed as an attractive cell source for cartilage regeneration. …”
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Corrigendum to “New Issues in the Management of Osteoporosis” by Joonas Sirola, Manuel Diaz Curiel, Risto Honkanen, Jun Iwamoto

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Gel-Based Autologous Chondrocyte Implantation in a Patient with Noncontained Osteochondral Knee Defect at 9-Year Follow-Up by Ujjval Deliwala, Sumit Jain Sethia

“…Osteochondritis dissecans (OCD) is a disorder of the subchondral bone affecting the adjacent articular cartilage that may lead to cartilage and bone fragment detachment. …”
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Morphology of the rat knee joint after intraarticular injection of hydroxymethyl-quinoxaline dioxide by A.V.  Degtiar

“…The synovial membrane of the capsule was thickened, and synoviocytes were hypertrophied. The articular cartilage contains single cells with dense nuclei only in the superficial parts, but in general, the cytoarchitectonics of articular cartilage was preserved. …”
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Superior Thyroid Cornu Anatomical Variation Causing Globus Pharyngeous and Dysphagia by Jiannis K. Hajiioannou, Vasiliki Florou, Panagiotis Kousoulis

“…Rare case presentation of thyroid cartilage variation causing globus sensation and dysphagia. …”
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Vitamin D Receptor Genetic Variations May Associate with the Risk of Developing Late Fracture-Related Infection in the Chinese Han Population by Xing-qi Zhao, Kun Chen, Hao-yang Wan, Si-ying He, Han-jun Qin, Bin Yu, Nan Jiang

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The Effects of Morus alba and Acacia catechu on Quality of Life and Overall Function in Adults with Osteoarthritis of the Knee by Douglas S. Kalman, Susan J. Hewlings

“…Early intervention with UP1306 aimed at reducing bone and cartilage degradation through reported inhibition of catabolic proinflammatory pathways may help to prevent joint cartilage damage. …”
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Molecular and Cellular Pathways Contributing to Joint Damage in Rheumatoid Arthritis by Qinghua Fang, Chun Zhou, Kutty Selva Nandakumar

“…Rheumatoid arthritis is a chronic autoimmune syndrome associated with several genetic, epigenetic, and environmental factors affecting the articular joints contributing to cartilage and bone damage. Although etiology of this disease is not clear, several immune pathways, involving immune (T cells, B cells, dendritic cells, macrophages, and neutrophils) and nonimmune (fibroblasts and chondrocytes) cells, participate in the secretion of many proinflammatory cytokines, chemokines, proteases (MMPs, ADAMTS), and other matrix lysing enzymes that could disturb the immune balance leading to cartilage and bone damage. …”
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Case Report of Multiple Tracheostomy Revisions due to Persistent, Recurrent Cuff Leak by Jian P. Azimi-Bolourian, Issa A. Hanna, George W. Williams

“…Aberrant tracheal cartilage should be on the differential diagnosis for cuff leaks subsequent to surgical tracheostomy (ST) or percutaneous dilatational tracheostomy (PDT).…”
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A Rare Case of Malignant Tumor of the Larynx with Good Prognosis: Laryngeal Chondrosarcoma by Abderrahim Elktaibi, Issam Rharrassi, Nabil Hammoune, Youssef Darouassi, Mohammed Amine Hanine, Haddou Ammar

“…Laryngeal chondrosarcoma is a rare laryngeal tumor that most frequently originates from the cricoid cartilage. The majority of lesions are low grade and the distinction from benign chondromas must be made. …”
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Current Perspectives in Mesenchymal Stem Cell Therapies for Osteoarthritis by Baldur Kristjánsson, Sittisak Honsawek

“…In this review the history and early uses of MSCs in cartilage regeneration are reviewed and different approaches in current trends are explained and evaluated.…”
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Osteoperiosteal versus osteochondral for autologous transplantation in the treatment of large cystic osteochondral lesions of the talus by Lequan Liu, Jiangtao Jin, Jinping Pan, Huikang Guo, Sen Li, Jisheng Li, Zheng Zhang

“…Second-look arthroscopy was performed 12 months postoperatively, and the cartilage repair was assessed with the criteria of the International Cartilage Repair Society (ICRS). …”
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Relationship between insertions of the tibialis anterior and peroneus longus and first tarsometatarsal joint degeneration by Kodai Sakamoto, Mutsuaki Edama, Tomoki Hirai, Hirotake Yokota, Ryo Hirabayashi, Chie Sekine, Tomonobu Ishigaki, Makoto Komiya, Taku Toriumi, Ikuo Kageyama

“…The severity of articular cartilage degeneration was assessed in five stages using the International Cartilage Repair Society scale. …”
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Multiscale correlations between joint and tissue-specific biomechanics and anatomy in postmortem ovine stifles by Aritra Chatterjee, Zachary Robert Davis, Timothy Lescun, Deva D. Chan

“…Further, the viscoelastic properties of the tendons and ligaments correlate positively with joint laxity forces; however, no such correlations were observed for the cartilage and menisci. We also found weak inverse correlation between tissue viscoelasticity and T 2 * for MCL; and positive correlations for cartilage and menisci, LCL and PCL respectively. …”
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Inhibition of miR-182-5p Targets FGF9 to Alleviate Osteoarthritis by Yang Sun, Sanmao Su, Mengjun Li, Ang Deng

“…Hematoxylin–eosin (HE) and safranin O-fast Green (S–O) staining were utilized to access cartilage damage. Ki67 expression in cartilage was detected using immunohistochemistry (IHC). …”
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Characterization of Different Sources of Human MSCs Expanded in Serum-Free Conditions with Quantification of Chondrogenic Induction in 3D by Hugo Fabre, Maxime Ducret, Olivier Degoul, Jonathan Rodriguez, Emeline Perrier-Groult, Elisabeth Aubert-Foucher, Marielle Pasdeloup, Céline Auxenfans, Colin McGuckin, Nico Forraz, Frédéric Mallein-Gerin

“…Mesenchymal stem cells (MSCs) represent alternative candidates to chondrocytes for cartilage engineering. However, it remains difficult to identify the ideal source of MSCs for cartilage repair since conditions supporting chondrogenic induction are diverse among published works. …”
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The Interplay of Aging and PANoptosis in Osteoarthritis Pathogenesis: Implications for Novel Therapeutic Strategies by Liu S, Zhang G, Li N, Wang Z, Lu L

“…In OA, dysregulated apoptosis, necroptosis, and pyroptosis, particularly in chondrocytes, exacerbate cartilage damage. Apoptosis, mediated by the JNK pathway, reduces chondrocyte density, while necroptosis and pyroptosis, involving RIPK-1/RIPK-3 and the NLRP3 inflammasome, respectively, amplify inflammation and cartilage destruction. …”
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Association between meniscal extrusion and disease severity in knee osteoarthritis: a retrospective case-control study by Peng Wu

“…Various parameters, including Kellgren/Lawrence classification, imaging findings, cartilage damage grading, physical function assessments, and correlation analyses, were used to evaluate the relationship between meniscal extrusion and disease progression. …”
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KLF9-GRK5-HDAC6 axis aggravates osteoarthritis pathogenesis by promoting chondrocyte extracellular matrix degradation and apoptosis by Xiaonan Zhou, Peng Jiang, Huangqi Tan, Yanfang Wang, Lunhao Bai

“…Abstract Osteoarthritis (OA) is a degenerative joint disease that affects the cartilage and surrounding tissues. The transcription factor Kruppel-like family factor 9 (KLF9) has been identified as a regulator of tumorigenesis. …”
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