The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: A randomized trial by Gansheng Tan, Anna L Huguenard, Kara M Donovan, Phillip Demarest, Xiaoxuan Liu, Ziwei Li, Markus Adamek, Kory Lavine, Ananthv K Vellimana, Terrance T Kummer, Joshua W Osbun, Gregory J Zipfel, Peter Brunner, Eric C Leuthardt

“…Given the association between cardiac complications and elevated risk of poor clinical outcomes after SAH, it is essential to characterize the cardiovascular effects of taVNS to ensure this approach is safe in this fragile population. …”
Get full text

Evaluation of a 90-minute school-based resuscitation course with 340 middle school students – a multicenter intervention study by Josephina Kehlert

“…The findings of this study support the statewide implementation of resuscitation training for middle school students as part of a greater ambition to increase bystander assistance in out-of-hospital cardiac arrest. HintergrundZiel dieser Studie war es, den Lernerfolg eines 90-minütigen Reanimationsunterrichts, der von zuvor speziell ausgebildeten Lehrkräften in Brandenburg unterrichtet wurde, vor einer landesweiten Einführung dieser Kurse explorativ zu evaluieren.MethodenIn fünf öffentlichen Schulen unterrichteten Lehrkräfte, die von professionellen Erste-Hilfe-Ausbildern geschult wurden, 340 Schüler der siebten Klasse (7. …”
Get full text

Improving Growth Performance, Biochemical Parameters and Reducing Mortality due to Ascites in Broilers by Propranolol Inclusion by Shahriar Saidian, Somaya Farahmand, Mokhtar Fathi, Salar Saifi

“…B-blockers (or b-adrenergic antagonists) are a group of drugs widely used in the treatment of cardiovascular diseases, namely arterial hypertension, cardiac arrhythmias, and angina pectoris as well as other types of pathologies such as anxiety or glaucoma. …”
Get full text

Longitudinal immunogenicity cohort study of SARS-CoV-2 mRNA vaccines across individuals with different immunocompromising conditions: heterogeneity in the immune response and cruci... by Annalisa Ciabattini, Elena Pettini, Fabio Fiorino, Jacopo Polvere, Simone Lucchesi, Chiara Coppola, Simone Costagli, Gabiria Pastore, Anna Sicuranza, Monica Tozzi, Arianna Lippi, Francesca Panza, Monica Bocchia, Alessandro Bucalossi, Guido Garosi, David Bennett, Sonia Bernazzali, Massimiliano Fabbiani, Francesca Montagnani, Donata Medaglini

Get full text

Multi-omics uncovers immune-modulatory molecules in plasma contributing to resistance exercise-ameliorated locomotor disability after incomplete spinal cord injury by Ren Zhou, Jibao Chen, Yunhan Tang, Chuijin Wei, Ping Yu, Xinmei Ding, Li’ao Zhu, Jiajia Yao, Zengqiang Ouyang, Jing Qiao, Shumin Xiong, Liaoliao Dong, Tong Yin, Haiqing Li, Ye Feng, Lin Cheng

Get full text

MVP Risk score y nuevo diagnóstico de fibrilación auricular: estudio de cohorte prospectivo PREFATE by Josep L. Clua-Espuny, Delicia Gentille-Lorente, Alba Hernández-Pinilla, Eva Maria Satué-Gracia, Meritxell Pallejà-Millán, Francisco M. Martín-Luján

“…Measurements: At baseline, a standard ECG, MVP risk score assessment, and cardiac rhythm monitoring for 15 days using the FibricheckR App were performed. …”
Get full text

Bridging animal models and humans: neuroimaging as intermediate phenotypes linking genetic or stress factors to anhedonia by Huiling Guo, Yao Xiao, Shuai Dong, Jingyu Yang, Pengfei Zhao, Tongtong Zhao, Aoling Cai, Lili Tang, Juan Liu, Hui Wang, Ruifang Hua, Rongxun Liu, Yange Wei, Dandan Sun, Zhongchun Liu, Mingrui Xia, Yong He, Yankun Wu, Tianmei Si, Fay Y. Womer, Fuqiang Xu, Yanqing Tang, Jie Wang, Weixiong Zhang, Xizhe Zhang, Fei Wang

Get full text

ApoB100 remodeling and stiffened cholesteryl ester core raise LDL aggregation in familial hypercholesterolemia patients by Maria Teresa La Chica Lhoëst, Andrea Martínez, Eduardo Garcia, Jany Dandurand, Anna Polishchuk, Aleyda Benitez-Amaro, Ana Cenarro, Fernando Civeira, Amable Bernabé, David Vilades, Joan Carles Escolà-Gil, Valerie Samouillan, Vicenta Llorente-Cortes

Get full text

Características clínicas y tratamiento farmacológico de los pacientes con insuficiencia cardíaca en una cohorte de atención primaria by Maria Giner-Sorian, Ramon Monfà, Roser Vives, Silvia Fernández-García, Antoni Vallano, Rosa Morros

“…We highlight a low registry of cardiac function, LVEF and NYHA. The frequency of drug use for HF was different between populations and differed from the recommendations.…”
Get full text

Desensitization With Imlifidase for HLA-Incompatible Deceased Donor Kidney Transplantation: A Delphi International Expert Consensus by Lucrezia Furian, Uwe Heemann, Mats Bengtsson, Oriol Bestard, Isabelle Binet, Georg A. Böhmig, John Boletis, David Briggs, Frans H. J. Claas, Lionel Couzi, Emanuele Cozzi, Marta Crespo, Aiko P. J. De Vries, Fritz Diekmann, Magdalena Durlik, Denis Glotz, Ilkka Helantera, Annette Jackson, Stanley C. Jordan, Dirk Kuypers, Dirk Kuypers, Carmen Lefaucheur, Christophe Legendre, Tomas Lorant, Umberto Maggiore, Nizam Mamode, Smaragdi Marinaki, Annick Massart, Thomas Müller, Rainer Oberbauer, Lutz Renders, Dave Roelen, Jean-Luc Taupin, Ondřej Viklický, Angeliki Vittoraki, Annelies E. de Weerd, Maarten Naesens

Get full text

Efficacy of Alginate-Antacid Medication in the Treatment of Patients with Gastroesophageal Reflux Disease by O. A. Storonova, A. S. Trukhmanov, V. T. Ivashkin

“…In group 1, 10 patients were examined using a probe pull-through technique with the purpose of determining pH levels in the cardiac stomach, in the area of the gastro-esophageal junction and in the esophagus at a level of 5 cm above the LES, both in the fasting state and after eating, as well as prior and after using alginate-antacid preparations. …”
Get full text

HELLO: a protocol for a cluster randomized controlled trial to enhance interpersonal relationships and team cohesion among ICU healthcare professionals by Elie Azoulay, Nancy Kentish Barnes, Sheila Nainan Myatra, Maria-Cruz Martin Delgado, Yaseen Arabi, Carole Boulanger, Giovanni Mistraletti, Maria Theodorakopoulou, Vernon Van Heerden, José-Artur Paiva, Oktay Demirkýran, Gabriel Heras La Calle, Abdulrahman Al Fares, Gaston Burghi, Guy Francois, Anita Barth, Jan De Waele, Samir Jaber, Michael Darmon, Maurizio Cecconi

Get full text

Differential Prognosis of True Bifurcation Lesions According to Left Main Versus Non–Left Main Location and Treatment Strategy by Ki Hong Choi, Chang‐Wook Nam, Francesco Bruno, Yun‐Kyeong Cho, Leonardo De Luca, Jeehoon Kang, Alessio Mattesini, Young Bin Song, Alessandra Truffa, Hyo‐Soo Kim, Wojciech Wańha, Woo Jung Chun, Sebastiano Gili, Gerard Helft, Seung Hwan Han, Bernardo Cortese, Cheol Hyun Lee, Javier Escaned, Hyuck‐Jun Yoon, Alaide Chieffo, Joo‐Yong Hahn, Guglielmo Gallone, Seung‐Hyuk Choi, Gaetano De Ferrari, Bon‐Kwon Koo, Giorgio Quadri, Seung‐Ho Hur, Fabrizio D'Ascenzo, Hyeon‐Cheol Gwon, Ovidio de Filippo

“…The primary end point was major adverse cardiac events (MACEs; composite of all‐cause death, myocardial infarction, target lesion revascularization, and stent thrombosis) at 800 days. …”
Get full text

Binding of LncDACH1 to dystrophin impairs the membrane trafficking of Nav1.5 protein and increases ventricular arrhythmia susceptibility by Genlong Xue, Jiming Yang, Yang Zhang, Ying Yang, Ruixin Zhang, Desheng Li, Tao Tian, Jialiang Li, Xiaofang Zhang, Changzhu Li, Xingda Li, Jiqin Yang, Kewei Shen, Yang Guo, Xuening Liu, Guohui Yang, Lina Xuan, Hongli Shan, Yanjie Lu, Yang Baofeng, Zhenwei Pan

“…Long noncoding RNAs (lncRNAs) are involved in the regulation of cardiac ion channels, while their influence on sodium channels remains unexplored. …”
Get full text

Association of chronic heart failure with mortality in old intensive care patients suffering from Covid‐19 by Raphael Romano Bruno, Bernhard Wernly, Georg Wolff, Jesper Fjølner, Antonio Artigas, Bernardo Bollen Pinto, Joerg C. Schefold, Detlef Kindgen‐Milles, Philipp Heinrich Baldia, Malte Kelm, Michael Beil, Sigal Sviri, Peter Vernon vanHeerden, Wojciech Szczeklik, Arzu Topeli, Muhammed Elhadi, Michael Joannidis, Sandra Oeyen, Eumorfia Kondili, Brian Marsh, Finn H. Andersen, Rui Moreno, Susannah Leaver, Ariane Boumendil, Dylan W. De Lange, Bertrand Guidet, Hans Flaatten, Christian Jung, COVIP study group

“…Methods and results Patients with pre‐existing CHF were subclassified as having ischaemic or non‐ischaemic cardiac disease; patients with a documented ejection fraction (EF) were subclassified according to heart failure EF: reduced (HFrEF, n = 132), mild (HFmrEF, n = 91), or preserved (HFpEF, n = 103). …”
Get full text

Clinical validation of an artificial intelligence-based decision support system for diagnosis and risk stratification of heart failure (STRATIFYHF): a protocol for a prospective, m... by Prithwish Banerjee, Guy A MacGowan, Frans H Rutten, Iacopo Olivotto, Petar M Seferović, Jonathan Mant, Djordje G Jakovljevic, Oscar Fernandez, Josep Darbà, Nduka C Okwose, Jose Zamorano, Duncan Edwards, David Sinclair, Lazar Velicki, Amy Groenewegen, Lars S Maier, Dimitris Fotiadis, Sarah Jane Charman, Annamaria Del Franco, Maria Tafelmeier, Andrej Preveden, Cristina Garcia Sebastian, Amy S Fuller, Anne Pauline Nelissen, Petros Malitas, Aikaterini Zisaki, Zoran Bosnic, Petar Vracar, Fausto Barlocco, Marta Jiménez-Blanco Bravo, Nenad Filipovic, Bano Fatima, Williams Kate, Fornaro Alessandra, Milovancev Aleksandra, Ascanio Meritxell, Aguera Ainoa, Pičulin Matej, Flis Borut, Boucharas Dimitrios, Manousos Dimitris, Tsiknakis Manolis, Kassiotis Thomas, Sustersic Tijana, Milicevic Bogdan, Hobbs FD Richard, Kaagman Onno

“…All participants will have their medical history recorded, along with data on physical examination (signs and symptoms), blood tests including serum natriuretic peptides levels, ECG and echocardiogram results, as well as demographic, socioeconomic and lifestyle data, and use of complete novel technologies (cardiac output response to stress test and voice recognition biomarkers). …”
Get full text

Comments on: “Early High-Titer Convalescent Plasma Therapy in Patients with Moderate and Severe COVID-19” [Transfusion and Apheresis Science 61 (2022) 103321] by Seyed Reza Hosseiniara

“…Specifically, 88% of patients experienced cardiac events, and 66% encountered thrombotic events while undergoing convalescent plasma treatment for COVID-19.10 Moreover, some studies reporting positive outcomes associated with convalescent plasma therapy did not utilize this treatment in isolation but rather as an adjunct to standard therapies.11Among studies that employed convalescent plasma therapy alone, Agarwal et al.,12 noted minor improvements in shortness of breath and fatigue; however, the evaluators were not blinded to subject data, which raises concerns about the reliability of their findings. …”
Get full text

Prognostic Value of Postpercutaneous Coronary Intervention Murray-Law-Based Quantitative Flow Ratio by Daixin Ding, PhD, Jinlong Zhang, MD, PhD, Peng Wu, PhD, Zhiqing Wang, MD, PhD, Huiping Shi, MSc, Wei Yu, PhD, Xinyang Hu, MD, PhD, Jeehoon Kang, MD, Joo-Yong Hahn, MD, Chang-Wook Nam, MD, Joon-Hyung Doh, MD, Bong-Ki Lee, MD, Weon Kim, MD, Jinyu Huang, MD, Fan Jiang, MD, Hao Zhou, MD, Peng Chen, MD, Lijiang Tang, MD, Wenbing Jiang, MD, Xiaomin Chen, MD, Wenming He, MD, Sung Gyun Ahn, MD, Myeong-Ho Yoon, MD, Ung Kim, MD, You-Jeong Ki, MD, Eun-Seok Shin, MD, Seung-Jea Tahk, MD, Jun Pu, MD, William Wijns, MD, PhD, Jian’an Wang, MD, PhD, Bon-Kwon Koo, MD, PhD, Shengxian Tu, PhD

“…The primary endpoint was 2-year target vessel failure, including cardiac death, target vessel myocardial infarction, and target vessel revascularization. …”
Get full text

Clonal hematopoiesis of indeterminate potential and type 2 diabetes mellitus among patients with STEMI: from a prospective cohort study combing bidirectional Mendelian randomizatio... by Xiaoxiao Zhao, Jiannan Li, Shaodi Yan, Yu Tan, Runzhen Chen, Nan Li, Jinying Zhou, Chen Liu, Peng Zhou, Yi Chen, Hongbing Yan, Hanjun Zhao, Li Song

“…ASXL1 CHIP mutation which displayed a striking correlation with cardiac death (HR: 3.14; 95% CI 1.24–7.93; P < 0.05) with consistent associations observed among T2DM subgroup (HR: 4.51; 95% CI 1.30–15.6; P < 0.05). …”
Get full text

Bioinspired hierarchical porous tough adhesive to promote sealing of high-pressure bleeding by Yinghao Li, Dongling Xiao, Weixi Yan, Meilin Jiang, Ju Tan, Zhongliang Qin, Jingting Zhou, Yue Sun, Mingcan Yang, Guanyuan Yang, Yawei Gu, Yong Liu, Chuhong Zhu

“…They synergistically withstand considerable hydraulic pressure of approximately 700 mmHg and demonstrate exceptional tissue adhesion and sealing in rat cardiac and canine aortic hemorrhages, outperforming the commercially available bioadhesives. …”
Get full text