Interventional real-time molecular MRI for targeting early myocardial injury in a pig model by Timo Heidt, Simon Reiss, Julien Thielmann, Christian Weber, Alexander Maier, Thomas Lottner, Heidi R. Cristina-Schmitz, Timon Bühler, Diana Chiang, Claus Jülicher, Carolin Wadle, Ingo Hilgendorf, Dennis Wolf, Gavin Tumlinson, Luis Hortells, Dirk Westermann, Michael Bock, Constantin von zur Mühlen

“…Here, we assessed ischemic cardiac lesions non-invasively directly after ischemia/reperfusion (I/R) in a porcine model by advanced MRI techniques and molecular imaging, targeting the cell adhesion molecule P-selectin functionalized with microparticles of iron oxide (MPIO). …”
Get full text

Can the Onset of Type 2 Diabetes Be Delayed by a Group-Based Lifestyle Intervention in Women with Prediabetes following Gestational Diabetes Mellitus (GDM)? Findings from a Randomi... by Angela O’Dea, Marie Tierney, Brian E. McGuire, John Newell, Liam G. Glynn, Irene Gibson, Eoin Noctor, Andrii Danyliv, Susan B. Connolly, Fidelma P. Dunne

Get full text

Kounis Syndrome as First Manifestation of Allergic Sensitization by D. Forlani, G. Scarano, A. D’Alleva, M. Di Marco, L. Paloscia, A. Gatta, L. Della Valle, A. Farinelli, A. Lumaca, C. Petrarca, R. Paganelli, L. Di Giampaolo, M. Di Gioacchino

“…Conversely, measurement of cardiac biomarkers during anaphylaxis, even without obvious signs of myocardial ischemia, might identify patients at risk of myocardial injury.…”
Get full text

Normothermic Ex Vivo Heart Perfusion with Mesenchymal Stem Cell-Derived Conditioned Medium Improves Myocardial Tissue Protection in Rat Donation after Circulatory Death Hearts by Zifeng Zeng, Liwei Xu, Yu Xu, Yongsheng Ruan, Deshen Liu, Jiale Li, Chuanjie Niu, Shaoyi Zheng, Pengyu Zhou, Zezhou Xiao

“…Vehicle or CM (300 μl) was added to the perfusate at the beginning of the perfusion process. The cardiac function of DCD hearts in the DCD-Control and DCD-CM groups was measured every 30 minutes. …”
Get full text

Similarities and Differences between Coronavirus Disease 2019-related Multisystem Inflammatory Syndrome in Children and Kawasaki Disease in Indian Patients by Utkarsh Singh, Suhas Prabhu, Deepak Phalgune

“…The primary objectives were to compare the gastrointestinal manifestations between the two groups, whereas the secondary objectives were to compare the mucocutaneous and cardiac manifestations. Results: The mean duration of fever was significantly longer in children with KD compared to those with MIS-C. …”
Get full text

Preclinical use of a clinically-relevant scAAV9/SUMF1 vector for the treatment of multiple sulfatase deficiency by Maximiliano Presa, Rachel M. Bailey, Somdatta Ray, Lauren Bailey, Saurabh Tata, Tara Murphy, Pierre-Alexandre Piec, Harold Combs, Steven J. Gray, Cathleen Lutz

“…The treated mice show wide distribution of the SUMF1 gene, no signs of toxicity or neuropathy, improved vision and cardiac function, and no behavioral deficits. One-year post treatment, tissues show increased sulfatase activity, indicating functional SUMF1. …”
Get full text

Safety and Efficacy of Cryoballoon Ablation of Atrial Fibrillation in relation to the Patients’ Age: Results from a Large Real-World Multicenter Observational Project by Luigi Sciarra, Saverio Iacopino, Giuseppe Arena, Claudio Tondo, Paolo Pieragnoli, Giulio Molon, Massimiliano Manfrin, Antonio Curnis, Antonio Dello Russo, Giovanni Rovaris, Giuseppe Stabile, Leonardo Calò, Gabriele Boscolo, Roberto Verlato

Get full text

tRF-AspGTC Promotes Intracranial Aneurysm Formation by Controlling TRIM29-Mediated Galectin-3 Ubiquitination by Chao Wang, Bing Yu, Han Zhou, Huanting Li, Shifang Li, Xiaolu Li, Wentao Wang, Yugong Feng, Tao Yu

Get full text

Postoperative Pulmonary Hemodynamics and Systemic Inflammatory Response in Pediatric Patients Undergoing Surgery for Congenital Heart Defects by Maria Francilene S. Souza, Juliano G. Penha, Nair Y. Maeda, Filomena R. B. G. Galas, Kelly C. O. Abud, Eloisa S. Carvalho, Ana Maria Thomaz, Claudia R. P. Castro, Juliana Pereira, Antonio Augusto Lopes

“…There is scarce information about the relationships between postoperative pulmonary hemodynamics, inflammation, and outcomes in pediatric patients with congenital cardiac communications undergoing surgery. We prospectively studied 40 patients aged 11 (8–17) months (median with interquartile range) with a preoperative mean pulmonary arterial pressure of 48 (34–54) mmHg who were considered to be at risk for postoperative pulmonary hypertension. …”
Get full text

Common Risk Factors of Myocardial Infarction and Some Socio Demographic Characteristics in Sulaimani City by Bayan Omar Sharif, Samir Y. Lafi

“…The current study’s main aims were to explore the potential association between several predisposing factors and heart attack in Sulaimani, Iraq, and to some socio demographic in this participant. 165 contributors who were attending to the Cardiac Specialty Hospital, (Coronary Care Unit), and they were definitely diagnosed as having MI participated in the current study between 2015 and 2016; in Sulaimani, Iraq.  …”
Get full text

Evaluation of 30-day mortality in patients undergoing gastrointestinal endoscopy in a tertiary hospital: a 3-year retrospective survey by Philippe Bichard, Jean-Louis Frossard, Laurent Spahr, Nicolas Goossens, Olivier Chatelanat, Laurent Bochatay, Caroline Bastid

“…Major causes of death were oncological progression (72/251; 28.68%), cardiopulmonary failure or cardiac arrest of unkown origin (62/251; 24,7%) and liver failure (20/251; 7.96%). …”
Get full text

Diagnosis of Coxiella burnetii endocarditis by using nanopore targeted sequencing: a case report by Xinsheng Yan, Qimei Wei, Tingting Liu, Dong Wang, Zhenlu Zhang

“…Case presentation The present study reports the case of a 57-year-old male patient who was admitted with a diagnosis of severe aortic stenosis. Cardiac computed tomography (CT) angiography revealed a diastolic aortic valve malformation with significant leaflet thickening, calcification and pseudoaneurysm formation, the etiology of which was considered to be due to infectious possibilities. …”
Get full text

Heparin rebound in patients undergoing off-pump coronary artery bypass grafting surgery: a single-center retrospective study by Fei Jiang, Yang Xu, Shan-shan Hu, Jin-quan Wang, Yun-tai Yao, the Evidence in Cardiovascular Anesthesia (EICA) Group

“…Abstract Background Heparin, an anticoagulant used in cardiac surgery, can result in heparin rebound (HR), where it returns postoperatively despite being neutralized with protamine. …”
Get full text

Evaluation and Optimization Research on the Spatial Distribution of Automated External Defibrillators Based on a Genetic Algorithm: A Case Study of Central Urban District of Nanjin... by Ge Shi, Jiahang Liu, Chuang Chen, Jingran Zhang, Jinghai Xu, Yu Chen, Jiaming Na, Wei Chen

“…Automated external defibrillators (AEDs) are portable emergency medical devices critical for resuscitating individuals experiencing sudden cardiac arrest. The installation of AEDs in public spaces is essential for enhancing society’s emergency response capabilities. …”
Get full text

Assessment of Clinical Features in HIV-Infected Patients with Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention in China by Ying Liu, Yongfu Chen, Yiwei Hao, Jing Xiao, Bei Li, Leidan Zhang, Junyan Han, Hongxin Zhao

“…In addition, the risk of major adverse cardiac and cerebrovascular events at 1 year was similar in both groups. …”
Get full text

Daily Chronic Intermittent Hypobaric Hypoxia Does Not Induce Chronic Increase in Pulmonary Arterial Pressure Assessed by Echocardiography by Jeremias Götschke, Pontus Mertsch, Nikolaus Kneidinger, Diego Kauffmann-Guerrero, Jürgen Behr, Rudolf Maria Huber, Frank Reichenberger, Katrin Milger

“…LA echocardiography showed normal right and left cardiac dimensions and function in all subjects. Systolic PAP (sPAP) and tricuspid annular plane systolic excursion (TAPSE) at rest were similar in both groups. …”
Get full text

Causal Inference for Hypertension Prediction With Wearable E lectrocardiogram and P hotoplethysmogram Signa... by Ke Gon g, Yifan Chen, Xinyue Song, Zhizhong Fu, Xiaorong Ding

“…Hypertension can be detected in a timely manner with cardiac signals, such as through an electrocardiogram (ECG) and photoplethysmogram (PPG) , which can be observed via wearable sensors. …”
Get full text

Effects of vitamin C on cardiovascular oxidative stress induced by hypothyroidism in neonatal and juvenile rats by Farimah Beheshti, Reza Mohebbati, Mahmoud Hosseini, Saeed Niazmand, Masomeh Mirzaei, Mahdiyeh Hedayati-Moghadam, Maryam Paseban

“…At the end of the study, the rats were sacrificed, and serum, aortic, and cardiac tissues were collected for antioxidant evaluation. …”
Get full text

Cardiotoxicity of polystyrene nanoplastics and associated mechanism of myocardial cell injury in mice by Ziyi Xiong, Qiling Kong, Juan Hua, Qi Chen, Dandan Wang

“…This can lead to myocardial fibrosis and apoptosis and thus eccentric cardiac hypertrophy and impaired contractile function. …”
Get full text

Effect of <i>Cnidoscolus aconitifolius</i> (Family Euphorbiaceae) Aqueous Leaf Extract on Some Antioxidant Enzymes and Haematological Parameters of High Fat Diet and Streptozotocin... by EA Obichi, CC Monago, DC Belonwu

“…The animals were anaesthetized and sacrificed to obtain blood by cardiac puncture. Preliminary phytochemical analysis of CA showed the content of tannins (5.72±0.00), saponins (12.49±0.021), alkaloids (17.45 ±0.65), flavonoids  (23.72 ±0.02), cyanogenic glycosides (0.75 ±0.10) and phytate (1.97 ±0.06). …”
Get full text