Overexpressing the ClpC AAA+ unfoldase accelerates developmental cycle progression in Chlamydia trachomatis by Aaron A. Jensen, Saba Firdous, Lei Lei, Derek J. Fisher, Scot P. Ouellette

“…By analyzing the global transcriptional response to ClpC overexpression using RNA sequencing, we observed a shift to earlier expression of canonical late developmental cycle genes and other EB-associated genes. …”
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Effects of Sewage Sludge Compost on Carbon, Nitrogen, Phosphorus, and Sulfur Ratios and Soil Enzyme Activities in a Long-Term Experiment by Csilla Almási, Viktória Orosz, Timea Tóth, Mostafa M. Mansour, Ibolya Demeter, István Henzsel, Zsolt Bogdányi, Tamás András Szegi, Marianna Makádi

“…The main factors of treatment effects were plant-available phosphorus (ammonium lactate (AL)-soluble P₂O₅), total P, and NO₃-NO₂-N, based on principal component analysis. The canonical correspondent analyses revealed that phosphatase activities were affected by C:N, C:P, and N:P ratios and β-glucosidase was correlated with P forms and the E4/E6 ratio, while the soil pH strongly affected all soil enzymes. …”
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The Hubble Tension in Our Own Backyard: DESI and the Nearness of the Coma Cluster by Daniel Scolnic, Adam G. Riess, Yukei S. Murakami, Erik R. Peterson, Dillon Brout, Maria Acevedo, Bastien Carreres, David O. Jones, Khaled Said, Cullan Howlett, Gagandeep S. Anand

“…Calibrating the absolute magnitude of SNe Ia with the Hubble Space Telescope (HST) distance ladder yields D _Coma  = 98.5 ± 2.2 Mpc, consistent with its canonical value of 95–100 Mpc. This distance results in H _0  = 76.5 ± 2.2 km s ^−1 Mpc ^−1 from the DESI FP relation. …”
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The Role of β-Catenin in Th1 Immune Response against Tuberculosis and Profiles of Expression in Patients with Pulmonary Tuberculosis by Kunlong Xiong, Jinxia Niu, Ruijuan Zheng, Zhonghua Liu, Yanzheng Song, Lin Wang, Changtai Zhu, Lin Fan

“…β-Catenin is a key molecule of canonical Wnt/β-catenin pathway. Its roles and expression profiles in T cells of tuberculosis (TB) remain unclear. …”
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Identification and functional analysis of a novel SMARCC2 splicing variant in a family with syndromic neurodevelopmental disorder by Ming Li, Jingqi Lin, Hongjun Fei, Jinyu Liu, Yiyao Chen, Xu Han, Yanlin Wang, Jian Wang, Renyi Hua, Shuyuan Li, Niu Li

“…TA-clone sequencing of the RT-PCR fragments showed that the canonical splicing variant resulted in two distinct aberrant splicing events in SMARCC2 mRNA. …”
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Metabolomic and proteomic profiling of a burn-hemorrhagic shock swine model reveals a metabolomic signature associated with fatal outcomes by Bin Wei, Jinguang Zheng, Jiake Chai, Jianxiang Huang, Hongjie Duan, Shaofang Han, Xiaolin Yang, Wenjia Zhang, Fangchao Hu, Yirui Qu, Xiangyu Liu, Tian Liu, Yushou Wu, Yunfei Chi

“…Furthermore, the integrate analysis of the metabolomic and proteomic data was generalized by canonical correlation discriminant analysis, and the correlation between metabolites and mortality of the swine model was predicted using a multiple linear regression model by Pearson analysis. …”
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Documentando la arquitectura Republicana de Arequipa, Perú. valoración espacial, constructiva y estilística de tres casonas emblematicas by Daniel Málaga-Montoya, Fernando Cuzziramos-Gutiérrez, Tatiana Medina-Sánchez, Sergio Coll-Pla, Denis Leonardo Mayta-Ponce

“…A nivel constructivo, se destaca la preservación de estructuras de sillería de ignimbrita con muros de cajón, cubiertas con bóvedas de cañón en dos de los casos estudiados y cubiertas planas con rieles de hierro en uno de ellos, contabilizándose adiciones estructurales con materiales contemporáneos de hasta un 30%. …”
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“Subtype-precise” therapy leads diagnostic and therapeutic innovations: a new pattern for precision treatment of breast cancer by ZHANG Siwei, MA Ding, JIANG Yizhou, SHAO Zhimin

“…They divided it into four molecular subtypes and proposing corresponding precision treatment strategies: canonical luminal subtype (SNF1), sensitive to endocrine therapy; immunogenic subtype (SNF2), amenable to immunotherapy; proliferative subtype (SNF3), treatable by CDK4/6 inhibitors; and receptor tyrosine kinase-driven subtype (SNF4), targetable with tyrosine kinase inhibitors. …”
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Five-year carry-over effects in dune slack vegetation response to hydrology by Lisanne van Willegen, Hilary Wallace, Angela Curreli, Ciara Dwyer, John Ratcliffe, Davey L. Jones, Graham Williams, Martin Hollingham, Laurence Jones

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,,Cura animarum" of the Preachers Order in the Background of the Medieval Monkhoods Soul Salvation Development by Slawomir Zonenberg

“…While describing the Dominicans' pastoral work, the medieval Canon Law should also be referred to since there appeared the term "cura animarum ordinaria." …”
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Functional characterization of endocytic signals in the SynDIG/PRRT family members SynDIG1 and SynDIG4 in heterologous cells and neurons by David J. Speca, Chun-Wei He, Christina M. Meyer, Erin C. Scott, Erin C. Scott, Elva Díaz

“…We have identified a non-canonical μ2 binding sequence in SynDIG1 that induces aberrant accumulation at the plasma membrane of heterologous cells and primary rat hippocampal neurons, suggesting a conserved role for μ2-mediated endocytosis within the SynDIG family. …”
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Transcription factors MhyFIL1 and MhyFIL3 <i>(Monotropa hypopitys)</i> determine the asymmetric development of above-ground lateral organs in plants by A. V. Shchennikova, A. M. Kamionskaya, A. V. Nezhdanova, K. S. Gavrilova, M. A. Filyushin, E. Z. Kochieva, K. G. Skryabin

“…The aerial part of the plant is a reproductive axis with sterile bracts and inflorescence with a flower type canonical for higher plants. The origin of leaves and leaf-like lateral organs is associated, among other factors, with the evolution of the YABBY genes, which are divided into“vegetative” and evolutionarily recent“reproductive” genes, with regard to their expression profiles. …”
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Elocalcitol, a fluorinated vitamin D derivative, prevents high-fat diet-induced obesity via SCAP downregulation and miR-146a-associated mechanisms by Monika Jürgenson, Keerthana Chithanathan, Aivar Orav, Külli Jaako, Janeli Viil, Mithu Guha, Kalev Kask, Alexander Zharkovsky

“…In contrast, the administration of cholecalciferol (vitamin D)—a precursor to calcitriol, the biologically active form of vitamin D, did not affect significantly the signs of obesity and metabolic syndrome, suggesting that the anti-obese effects of elocalcitol are not related to the canonical vitamin D receptor (VDR). Further studies have demonstrated that the preventive effect of elocalcitol is associated with the decreased levels of sterol regulatory element-binding protein (SREBP) cleavage-activating protein (SCAP) and upregulation insulin-inducing gene-1 (Insig1) mRNA expression suggesting that the anti-obese effect of elocalcitol is mediated via inhibition of SREBP-mediated lipogenesis. …”
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PU.1 alleviates the inhibitory effects of cigarette smoke on endothelial progenitor cell function and lung-homing through Wnt/β-catenin and CXCL12/CXCR4 pathways by Xue He⁺, Yanan Cui⁺, Tiao Li, Lijuan Luo, Zihang Zeng, Yiming Ma, Yan Chen

“…Conclusions PU.1 alleviates the inhibitory effects of CSE on EPC function and lunghoming via activating the canonical Wnt/β-catenin pathway and CXCL12/CXCR4 axis. …”
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Distribution and dynamics for the ecological assessment of Asan Wetland through periphyton -a water quality indicator by Sazia Tabassum, C. B. Kotnala, A. K. Dobriyal, Mohammed Salman, Richa Bamola

“…The annual percentage composition of periphytic flora in the Asan wetland over 2 years indicates that Bacillariophyceae constituted the predominant group (89%–90%), succeeded by Chlorophyceae (7%–9%) and Cyanophyceae or Myxophyceae (1%–4%) across three sites. The canonical correspondence analysis (CCA) of periphyton among different sites during both years of the study suggested that S3 was more diverse, followed by S1 and S2, represented 64.93%, 35.07% of the variance with eigenvalues of 0.01794, 0.00968 respectively. …”
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Synergistic enhancement of hydrophobic dental adhesives: autonomous strengthening, polymerization kinetics, and hydrolytic resistance by Burak Korkmaz, Erhan Demirel, Qiang Ye, Qiang Ye, Anil Misra, Anil Misra, Candan Tamerler, Candan Tamerler, Candan Tamerler, Paulette Spencer, Paulette Spencer, Paulette Spencer

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Sposobin Remains. A Soviet Harmony Textbook’s Twisted Fate in China by Wai Ling Cheong, Ding Hong

“…The book soon attained canonic status in China and has been used in virtually all Chinese music institutions up to the present day. …”
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Guadua angustifolia biochar/TiO2 composite and biochar as bio-based materials with environmental and agricultural application by Luis A. Cañon-Tafur, Juan F. Mateus-Maldonado, Hair Santiago Lozano-Puentes, Carlos D. Herrera-Acosta, Juan J. Sánchez-Matiz, Lucía A. Díaz-Ariza, Geison Modesti Costa, Luis C. Jiménez-Borrego, Ana K. Carrascal-Camacho, Aura M. Pedroza-Rodríguez

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Transcriptomic profiles of monocyte-derived macrophages exposed to SARS-CoV-2 VOCs reveal immune-evasion escape driven by delta by Alessia Gallo, Josè Camilla Sammartino, Roberta Vazzana, Roberto Giambruno, Claudia Carcione, Nicola Cuscino, Salvatore Castelbuono, Vitale Miceli, Matteo Bulati, Daniele Lilleri, Irene Cassaniti, Pier Giulio Conaldi, Fausto Baldanti

“…Surprisingly, our data showed that macrophages exposed to the Delta variant exhibited a transcriptional profile more similar to the naïve control group, while macrophages exposed to the Omicron variant showed intermediate differentially expressed genes (DEGs) between the two groups. By checking the canonical markers for M1/M2 differentiation states, we did not observe any expression in macrophages exposed to the Delta variant, suggesting an M0 status, comparable to the naïve control group. …”
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Factorization of the Non-Normal Hamiltonian of Reggeon Field Theory in Bargmann Space by Abdelkader Intissar

“…<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msup><mi>A</mi><mo>*</mo></msup></semantics></math></inline-formula> and <i>A</i> are, respectively, the usual creation and annihilation operators of the one-dimensional harmonic oscillator obeying the canonical commutation relation <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>[</mo><mi>A</mi><mo>,</mo><msup><mi>A</mi><mo>*</mo></msup><mo>]</mo><mo>=</mo><mi>I</mi></mrow></semantics></math></inline-formula>. …”
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