Clinical Validation of the Defining Characteristics of the Nursing Diagnosis ‘Activity Intolerance’ in Patients With Acute Coronary Syndrome by Diana Isabel Cáceres Rivera, Luz Mileyde Jaimes Rojas, Luisa Yaneth Cristancho Zambrano, Jennifer Vanesa Acosta Barón, Diana Ivonne Cañon Gómez, Lyda Z. Rojas

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La utopía del “lector emancipado” en el proyecto estético de la “Nueva Poesía” by Rogelio Rosado Marrero

“…En consecuencia, este trabajo analiza algunas propuestas estéticas radicales de Vigo, Deisler y Padín con la finalidad de demostrar cómo el proyecto de la “Nueva Poesía” configura un tipo de lector cuya participación activa es vital para el cuestionamiento tanto de los cánones literarios vigentes como del sistema totalitario imperante en los años sesenta y setenta en Hispanoamérica. …”
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Identification of deleterious variants associated with male infertility genes in a cohort of idiopathic hypospermatogenesis patients by Nisha Sharma, Ashutosh Halder, Seema Kaushal, Manoj Kumar, Manish Jain

“…In silico analysis of variants shows deleterious and probably damaging effects on canonical transcripts of the genes.DiscussionThis exploratory genomic analysis conducted on idiopathic hypospermatogenesis patients shows prevalence of rare deleterious candidate variants in genes associated with human male infertility. …”
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Variations in the composition and frequency of celiac disease epitopes among synthetic wheat lines by Rahman Ebrahimzadegan, Ghader Mirzaghaderi

“…By searching the previously identified 121 epitopes and those with one mismatch in our amplicons, we found 54 different α-gliadins epitopes across our genotypes, four of which were new variants. The canonical epitopes were present in all lines, although their expression patterns varied. …”
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Lecture poétique des langues locales : cas de Nyanndra Mun (Proverbes) du Roi Salomon by Koffi Samuel N’ZI & Kouamé Gilles YAO

“…Au plan littéraire et linguistique, le corpus se révèle être un ancrage des assises des canons de la littérature et mise en fonctionnement des attentes stylistique, lexicale et sémantico-structurale, qui au demeurant satisfait les attentes des approches méthodologiques convoquées. …”
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Soil preferential flow dynamics in the southern drylands of India—a watershed based approach by Pushpanjali, K. S. Reddy, Ashish S. Dhimate, K. Karthikeyan, Josily Samuel, A. G. K. Reddy, N. Ravi Kumar, K. V. Rao, Prabhat Kumar Pankaj, Jagriti Rohit, Manoranjan Kumar, V. K. Singh

“…Vertical profile images were captured using a Canon EOS 1300D digital camera, producing high-resolution images (5184 × 3456 pixels). …”
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FNDC5/irisin mitigates the cardiotoxic impacts of cancer chemotherapeutics by modulating ROS-dependent and -independent mechanisms by Manish Kumar, Abhishek Singh Sengar, Anushree Lye, Pranesh Kumar, Sukhes Mukherjee, Dinesh Kumar, Priyadip Das, Suvro Chatterjee, Adele Stewart, Biswanath Maity

“…In fact, FNDC5 forms a co-precipitable complex with Chk1 alluding to possible intracellular actions for this canonically membrane-associated protein. Whereas FNDC5 overexpression in murine heart was cardioprotective, introduction of FNDC5-targeted shRNA into the myocardium was sufficient to trigger Bax up-regulation, ATR/Chk1 activation, oxidative stress, cardiac fibrosis, loss of ventricular function, and compromised animal survival. …”
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Clinical code usage in UK general practice: a cohort study exploring 18 conditions over 14 years by Christos Grigoroglou, Darren M Ashcroft, Evangelos Kontopantelis, David Reeves, Salwa S Zghebi, Rosa Parisi, Brian McMillan

“…Objective To assess the diagnostic Read code usage for 18 conditions by examining their frequency and diversity in UK primary care between 2000 and 2013.Design Population-based cohort studySetting 684 UK general practices contributing data to the Clinical Practice Research Datalink (CPRD) GOLD.Participants Patients with clinical codes for at least one of asthma, chronic obstructive pulmonary disease, diabetes, hypertension (HT), coronary heart disease, atrial fibrillation (AF), heart failure, stroke, hypothyroidism, chronic kidney disease, learning disability (LD), depression, dementia, epilepsy, severe mental illness (SMI), osteoarthritis, osteoporosis and cancer.Primary and secondary outcome measures For the frequency ranking of clinical codes, canonical correlation analysis was applied to correlations of clinical code usage of 1, 3 and 5 years. …”
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Detection of Bartonella spp. in foxes' populations in Piedmont and Aosta Valley (NW Italy) coupling geospatially-based techniques by Annalisa Viani, Tommaso Orusa, Sara Divari, Stella Lovisolo, Stefania Zanet, Riccardo Orusa, Enrico Borgogno-Mondino, Enrico Bollo

“…The study found that Bartonella spp. infections in foxes were positively associated with higher TCW values (>0.7). Canonical Correspondence Analysis further demonstrated a strong link between pathogen prevalence and municipal-level TCW, suggesting that TCW could be used as a parameter to facilitate disease management and control. …”
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Safety and Efficacy of Incorporating Actellic^® 300 CS into Soil Wall Plaster for Control of Malaria Vectors in Rural Northeastern Uganda by Tonny Jimmy Owalla, Emmanuel Okurut, Kenneth Ssaka, Gonsaga Apungia, Barbara Cemeri, Andrew Akileng, Basil Ojakol, Mark J. I. Paine, Hanafy M. Ismail, Thomas G. Egwang

“…In conclusion, HD4MC was safe and had comparable efficacy to canonical IRS.…”
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Integrin α8 is a useful cell surface marker of alveolar lipofibroblasts by Atsuki Fukada, Yasunori Enomoto, Ryo Horiguchi, Yoichiro Aoshima, Shiori Meguro, Hideya Kawasaki, Isao Kosugi, Tomoyuki Fujisawa, Noriyuki Enomoto, Naoki Inui, Takafumi Suda, Toshihide Iwashita

“…The transcriptome profile of ITGA8+ fibroblasts in adult mouse lungs, evaluated through two independent single-cell RNA-seq datasets, consistently showed higher expression of Tcf21 and Plin2, which are canonical markers of lipofibroblasts. ITGA8+ fibroblasts were primarily located in the alveolar area, particularly in the neighborhood of AT2. …”
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Dataset of microscale atmospheric flow and pollutant concentration large-eddy simulations for varying mesoscale meteorological forcing in an idealized urban environmentZenodo by Eliott Lumet, Thomas Jaravel, Mélanie C. Rochoux

“…These simulations reproduce the canonical MUST dispersion field campaign while perturbing the model's mesoscale meteorological forcing parameters. …”
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Midgut immune profiling and functional characterization of Aedes aegypti ABC transporter gene(s) using systemic and local bacterial challenges by Vikas Kumar, Shilpi Garg, Diksha Sisodia, Lalita Gupta, Sanjeev Kumar, Vishal Saxena

“…Studies on mosquito midgut transcriptome following pathogen exposure have revealed the presence of non-canonical immune genes, such as ABC transporters, whose function in insect immunity remains unexplored. …”
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La segunda edición del "Compendio tratto delle Osservationi della lingua castigliana" by Carmen Castillo Peña

“…Los objetivos que se persiguen son los siguientes: analizar los rasgos más salientes de la serie textual, explicitar el tipo de enmiendas que Giuffredi realiza al texto del Compendio de 1569, proponer una clasificación de las apostillas, mostrar cómo la misma obra pierde en la segunda edición su finalidad declaradamente didáctica para adquirir otra de naturaleza metagramatical en la que el texto ­-el Compendio propiamente dicho- queda subordinado al epitexto -la discusión de cuestiones normativas sobre el español y el italiano– y, por último, reflexionar sobre la ubicación de Argisto Giuffredi en el seno del canon historiográfico del hispanismo italiano.…”
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Scutellarein Inhibits Osteosarcoma Growth by Targeting the TLR4/TRAF6/NF-κB Pathway by Shi Y, Tang Y, Sun Z, Sui P, Shao Y, Wang Z, Zhang J, Gao M

“…Further studies revealed that SCU inhibited the canonical NF-κB pathway through its binding with TLR4, which disrupted the interaction of TLR4 and TRAF6. …”
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CRISPR/Cas9-editing of PRNP in Alpine goats by Aurélie Allais-Bonnet, Christophe Richard, Marjolaine André, Valérie Gelin, Marie-Christine Deloche, Aurore Lamadon, Gwendoline Morin, Béatrice Mandon-Pépin, Eugénie Canon, Dominique Thépot, Johann Laubier, Katayoun Moazami-Goudarzi, Ludivine Laffont, Olivier Dubois, Thierry Fassier, Patrice Congar, Olivier Lasserre, Tiphaine Aguirre-Lavin, Jean-Luc Vilotte, Eric Pailhoux

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Role of the Notch signaling pathway in porcine oocyte maturation by Pil-Soo Jeong, Hyo-Gu Kang, Dabin Cha, Se-Been Jeon, Min Ju Kim, Bong-Seok Song, Bo-Woong Sim, Sanghoon Lee

“…Finally, the involvement of canonical Notch signaling in oocyte maturation was confirmed by the decreased expression of HES and HEY family transcripts and proteins in the RO-treated COCs. …”
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Modeling Coupled Nonlinear Multilayered Dynamics: Cyber Attack and Disruption of an Electric Grid by Marc Mangel, Jimmie McEver

“…Second, we illustrate one of the Electric Power Research Institute scenarios for the reverse engineering of Advanced Metering Infrastructure (AMI) by coupling the synchronous motor equations for the generator and utility to the model of compromise. We derive a canonical condition for grid failure that relates the level of compromise at the time of detection of compromise and the dissipation parameter in the synchronous motor model. …”
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Adenoid cystic carcinoma of the breast, from diagnosis to management: a case report by Mendoza-Urbano Diana Marcela, Cañon Diana, Palazuelos Gloria Ines, Torres Fabio, Wills Beatriz, Rodriguez-Urrego Paula Andrea

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Bacterial interactions underpin worsening lung function in cystic fibrosis-associated infections by Damian W. Rivett, Lauren R. Hatfield, Helen Gavillet, Michelle Hardman, Christopher van der Gast

“…We found pathogenic interactions between species were limited to the most abundant species, which were composed of canonical CF pathogens (including Pseudomonas, Staphylococcus, Stenotrophomonas, and Achromobacter) and commensals. …”
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