Powdery mildew resistance of Nordic spring bread wheat accessions from the collection of the Vavilov Institute (VIR) by T. V. Lebedeva, A. N. Brykova, E. V. Zuev

“…Swedish cultivars ‘Sunnan’ (k-58177), ‘Canon’ (k-60992), ‘Sober’ (k-61080) ‘Dragon’ (k-61515) and ‘Dacke’ (k-63479) preserved their resistance to the powdery mildew population beginning from 1993. …”
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TNBC response to paclitaxel phenocopies interferon response which reveals cell cycle-associated resistance mechanisms by Nicholas L. Calistri, Tiera A. Liby, Zhi Hu, Hongmei Zhang, Mark A. Dane, Sean M. Gross, Laura M. Heiser

“…Single-cell RNA sequencing (scRNA-seq) of TNBC cells after paclitaxel treatment revealed upregulation of innate immune programs canonically associated with interferon response and downregulation of cell cycle progression programs. …”
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NLRP3 Inflammasome Simultaneously Involved in Autophagy and Phagocytosis of THP-1 Cells to Clear Aged Erythrocytes by Qin Li, Fengyong Zhao, Jiamin Zhang, Ying Yang, Zhonghui Guo, Chen Wang, Qixiu Yang, Ying Sun, Ziyan Zhu

“…The occurrence of autophagy was dominated by microtubule-associated protein 1A/1B-light chain 3- (LC3-) associated phagocytosis accompanied by canonical autophagy. A negative correlation exists between the clearance of RBCs by THP-1 cells and the degree of autophagy. …”
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Dysfunction in mitochondrial electron transport chain drives the pathogenesis of pulmonary arterial hypertension: insights from a multi-omics investigation by Xin Zhang, Jieling Li, Minyi Fu, Xijie Geng, Junjie Hu, Ke-Jing Tang, Pan Chen, Jianyong Zou, Xiaoman Liu, Bo Zeng

“…Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis investigated shared pathways, and canonical correlation analysis assessed gene-metabolite relationships. …”
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Influence of lemongrass and oregano essential oils and their combination on in vitro ruminal fermentation and greenhouse gas emissions in total mixed ration for dairy cows by Sara Glorio Patrucco, Alessandro Lotto, Martina Dorigo, Rita Fornaciari, Antonio Sagliano, Nicola Martinelli, Alessandra Cosani, Khalil Abid, Salvatore Barbera, Hatsumi Kaihara, Sonia Tassone

“…LEO reduced pH (−0.6%, p=0.004), while OEO increased oxidation capacity (+4.2%, p=0.004), but both parameters remained within physiological ranges. Canonical discriminant analysis confirmed distinct EOs effects, highlighting their potential as natural additives for improving ruminal fermentation and mitigating ruminant environmental footprint.…”
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Scrapie-Responsive Gene 1 Promotes Chondrogenic Differentiation of Umbilical Cord Mesenchymal Stem Cells via Wnt5a by Yuchuan Zhou, Tian Zheng, Lin Li, Yangfang Guo, Jiayu Xiao, Jin Wang, Zhiqin Du, Hui Gao, Weiwei Tang, Liusan Yang, Haiyan Hu, Xiaodan Wang, Mingyao Meng, Zongliu Hou

“…Our results showed that SCRG1 promotes chondrogenic differentiation of UCMSCs by inhibiting canonical Wnt/β-catenin signaling through Wnt5a. Our findings provide a future target for chondrogenic differentiation and cartilage regeneration.…”
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3D bioprinting of engineered exosomes secreted from M2-polarized macrophages through immunomodulatory biomaterial promotes in vivo wound healing and angiogenesis by Sayan Deb Dutta, Jeong Man An, Jin Hexiu, Aayushi Randhawa, Keya Ganguly, Tejal V. Patil, Thavasyappan Thambi, Jangho Kim, Yong-kyu Lee, Ki-Taek Lim

“…In a subcutaneous wound model, the 3D bioprinted COL@d-ECM/M2-Exo hydrogel displayed robust wound remodeling and hair follicle (HF) induction while reducing canonical pro-inflammatory activation after 14 days, presenting a viable therapeutic strategy for skin-related disorders.…”
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Climate and gypsum parent material shape biocrust communities and moss ecology in the Chihuahuan and Mojave Deserts by Katelyn G. Gobbie, Nicole Pietrasiak, Brian M. Jusko, Rebecca E. Drenovsky

“…Study sites were stratified by geomorphology and paired, so that every gypsum site was matched with a non-gypsum site in the same region. We employed canonical correspondence analysis (CCA) to relate the observed differences in biocrust abundance and composition across soil types to distinct environmental variables. …”
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An integrated investigation of mitochondrial genes in COPD reveals the causal effect of NDUFS2 by regulating pulmonary macrophages by Xiaoli Zou, Qiqing Huang, Tutu Kang, Shaoran Shen, Chenxi Cao, Jianqing Wu

“…Conclusions Our study established the causal linkage between mitochondrial malfunctions and COPD, providing a potential therapeutic avenue to alleviate pulmonary inflammation accounting for COPD by targeting mitochondria-related genes. NDUFS2, a canonical component of mitochondrial electron respiratory chain, was highlighted instrumental for the susceptibility of risk-exposed individuals to COPD.…”
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Relation of Wnt Signaling Pathway Inhibitors (Sclerostin and Dickkopf-1) to Left Ventricular Mass Index in Maintenance Hemodialysis Patients by Ahmed Bahie, Mohamed M. Abdalbary, Dalia Younis El-Sayed, Rasha Elzehery, Ghada El-Said, Ghada El-Kannishy, Ahmed M. Abd El Wahab

“…Several inhibitors regulate Wnt canonical pathways like Dickkopf-related protein-1 (Dkk-1) and sclerostin. …”
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<i>Ex Vivo</i> Regional Gene Therapy Compared to Recombinant BMP-2 for the Treatment of Critical-Size Bone Defects: An In Vivo Single-Cell RNA-Sequencing Study by Arijita Sarkar, Matthew C. Gallo, Jennifer A. Bell, Cory K. Mayfield, Jacob R. Ball, Mina Ayad, Elizabeth Lechtholz-Zey, Stephanie W. Chang, Osamu Sugiyama, Denis Evseenko, Jay R. Lieberman

“…Additionally, gene therapy was associated with an anti-inflammatory microenvironment; macrophages expressing canonical anti-inflammatory markers were more common in the gene therapy group. …”
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Linear Active Disturbance Rejection Control-Based Voltage Controller for Buck and Boost DC/DC Converters in DC Distribution Grids by Asimenia Korompili, Oemer Ekin, Marija Stevic, Veit Hagenmeyer, Antonello Monti

“…The formulation of the proposed L-ADRC model in the non-canonical form facilitates the employment of model-based estimation and feedback control methods, whose performance is determined through the design of several parameters. …”
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‘What a perennial delight is in hearing the French language spoken!’: Class, Language and Taste in the Maison de Molière’s French Performances in London (1871–1893) by Ignacio Ramos Gay

“…Through an examination of the reviews and impressions published by an array of professionals, including leading theatre critics at the time, dramatists, actors and aficionados, the research analyses the sociological, political, and aesthetic implications associated with the firm presence of the French language and French canonical plays in late Victorian London. The responses of theatre professionals inevitably raise the matter of high art by implicitly questioning which of the two theatrical traditions best reflect and recreate, through their language, such cultural standards: How is a language stylized to answer simultaneously to dramatic conventions and to expectations related to national sentiment? …”
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La cuestión de la dignidad en los mundos indígenas by Carolina Sanchez De Jaegher

“…En segundo lugar, al reforzar el locus enuntiationis y las prácticas desde las cuales se defiende la naturaleza y la dignidad, se abre un canon para la pluriversidad en "mundo donde quepan muchos mundos" (Ejército Zapatista de Liberación Nacional [EZLN], 1997). 20 En la puerta de entrada de una comprensión del mundo que supera con creces la comprensión occidental de él y el reconocimiento de que la experiencia cognitiva de las éticas de la Tierra es extremadamente diversa, este artículo problematizará la idea de dignidad en el paradigma de la universalidad (Guilherme y Dietz, 2017; Merali, 2014; Mignolo, 2011; Quijano, 2000).         …”
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Ecological analysis of plant community structure and soil effects in subtropical forest ecosystem by Sehrish Sadia, Muhammad Waheed, Shazia Firdous, Fahim Arshad, Beatrice Ambo Fonge, Abeer Al-Andal

“…Analyses using hierarchical clustering and ordination methods revealed significant differences in species composition among these communities, with NZM and DLS exhibiting the highest dissimilarity. Canonical Correspondence Analysis (CCA) indicated that environmental factors such as soil pH, available phosphorus (AP), and organic matter percentage (OM%) are crucial in shaping plant distribution, though the total explained variation remained relatively low. …”
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Extracellular vesicles in sputum of children with cystic fibrosis pulmonary exacerbations by Elad Ben-Meir, Lina Antounians, Shafinaz Eisha, Felix Ratjen, Augusto Zani, Hartmut Grasemann

“…Western blot analysis of EV protein extracts was used for EV canonical protein markers CD63, CD9 and flotillin-1 (FLOT1), as well as neutrophil elastase (NE), myeloperoxidase (MPO) and interleukin-8. …”
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New York as Shadow-Line in Philip Roth's Exit Ghost by Ellen Levy

“…Pour Nathan, désormais étranger, la réalité de la ville est une invitation à mesurer son aliénation dans le monde contemporain; mais aussi un encouragement à considérer les mots comme une alternative ou comme un reflet du monde dont il s'est retiré.Par une série de rencontres fortuites, Exit Ghost évoque aussi l'entrée de Nathan dans le canon de Roth une trentaine d'années auparavant (The Ghost Writer, 1979). …”
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Unveiling the signal valve specifically tuning the TGF-β1 suppression of osteogenesis: mediation through a SMAD1-SMAD2 complex by Ying-Wen Wang, Ching-Wei Luo

“…Results Distinct from the TGF-β1 inhibition on adipogenesis through canonical SMAD2/3 signaling, we clarified that TGF-β1 suppresses osteogenesis by inducing the formation of previously unidentified mixed SMADs mainly composed of SMAD1 and SMAD2, in which SMAD2 recruits more TGF-β1-induced co-repressors including HDAC1, TGIF1 and ATF3, whereas SMAD1 allows directing the whole transcriptional suppression complex to the cis-elements of osteogenic genes. …”
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Resultados de enfermería e intervención de soporte social para el autocontrol de la diabetes: estudio de consenso by Claudia Milena Garizábalo-Dávila, Wilson Cañon-Montañez, Alba Luz Rodríguez-Acelas

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Research on the Status of KAP and Countermeasures of the Scientific Research Level of TCM Rehabilitation Practitioners by Jian SONG, Zhizhen LIU, Jingsong WU, Juan PENG, Bin CHEN, Jia HUANG

“…In addition, the results of canonical correlation analysis showed that practice dimension was positive correlation to hospital classification, knowledge dimension and attitude dimension, the higher the knowledge and attitude dimensions, the greater the influence on the practice dimensions.Conclusion:There were uneven distribution of talents and uneven level of scientific research in different class of rehabilitation medical institutions. …”
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