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  1. 321

    Motif distribution and DNA methylation underlie distinct Cdx2 binding during development and homeostasis by Alireza Lorzadeh, George Ye, Sweta Sharma, Unmesh Jadhav

    Published 2025-01-01
    “…In adult cells, demethylation at these enhancers prevents ectopic Cdx2 binding, instead directing Cdx2 to its canonical motif without a CpG. This shift in Cdx2 binding facilitates Ctcf and Hnf4 recruitment, establishing super-enhancers during development and homeostatic enhancers in adult cells, respectively. …”
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  2. 322

    Autoregulation of the glial gene reversed polarity in Drosophila by Jamie L. Wood, Saroj Nepal, Bradley W. Jones

    Published 2025-01-01
    “…These results suggest that all three canonical RBSs may be cooperatively involved in autoregulation of repo expression.…”
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  3. 323

    Flexibility in PAM recognition expands DNA targeting in xCas9 by Kazi A Hossain, Lukasz Nierzwicki, Modesto Orozco, Jacek Czub, Giulia Palermo

    Published 2025-02-01
    “…This increased flexibility confers a pronounced entropic preference, which also improves recognition of the canonical TGG PAM. Furthermore, xCas9 enhances DNA binding to alternative PAM sequences during the early evolution cycles, while favouring binding to the canonical PAM in the final evolution cycle. …”
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  4. 324

    Caspase-11 Modulates Inflammation and Attenuates Toxoplasma gondii Pathogenesis by Sheryl L. Coutermarsh-Ott, John T. Doran, Caroline Campbell, Tere M. Williams, David S. Lindsay, Irving C. Allen

    Published 2016-01-01
    “…Recently, a noncanonical inflammasome has been characterized which functions through caspase-11 and appears to augment many biological functions previously considered to be dependent upon the canonical inflammasome. To better elucidate the function of this noncanonical inflammasome in toxoplasmosis, we utilized Asc−/− and Casp11−/− mice and infected these animals with T. gondii. …”
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  5. 325

    At the origins of the Jesuit presence in Sardinia by Roberto Ibba

    Published 2024-08-01
    “…In particular, the focus is on the case study of Sardara where the Jesuits took possession of a house in the centre of the village donated by Canon Giacomo Spiga of the diocese of Ales. The appropriation of ecclesiastical rents by the Company creates considerable tension with the parish priests of the community, who feel that they are impoverished and penalised. …”
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  6. 326

    Useful Solutions for Plane Wave Diffraction by Dielectric Slabs and Wedges by Gianluca Gennarelli, Giovanni Riccio

    Published 2012-01-01
    “…This work presents an overview of available uniform asymptotic physical optics solutions for evaluating the plane wave diffraction by some canonical geometries of large interest: dielectric slabs and wedges. …”
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  7. 327

    Linear and structural stability of a cell division process model by Vladimir Balan, Ileana Rodica Nicola

    Published 2006-01-01
    “…As well, for these values, the structural stability of the SODE is studied, using the five KCC-invariants of the second-order canonical extension of the SODE, and all the cases prove to be Jacobi unstable.…”
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  8. 328

    Equivalence between subshrubs and chaotic bands in the Mandelbrot set by G. Pastor, M. Romera, G. Alvarez, D. Arroyo, F. Montoya

    Published 2006-01-01
    “…From all the denominations of a chaotic band, we show the canonical form; that is, the one associated to the hyperbolic component that generates such a chaotic band. …”
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  9. 329

    Johann George Schreiber’s Atlas selectus: new findings by Paprotny Zbigniew

    Published 2024-01-01
    “…Discussed are recently discovered prototype versions of the Atlas which preceded series of “canonical” editions, and status of post-1795 copies. …”
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  10. 330

    Une histoire de la réception de Flaubert en Hongrie by Krisztina Horváth

    Published 2024-06-01
    “…Is it (still) true that Flaubert is reduced to Madame Bovary in the Hungarian canon of world literature? How is Flaubert treated in some major Hungarian critical texts and literary histories? …”
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  11. 331

    Invariants de Witt des involutions de bas degré en caractéristique 2 by Tignol, Jean-Pierre

    Published 2024-11-01
    “…A $3$-fold and a $5$-fold quadratic Pfister forms are canonically associated to every symplectic involution on a central simple algebra of degree $8$ over a field of characteristic $2$. …”
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  12. 332

    The Creation of Myth: Starting the First "Great Debate" in International Relations Theory by T. A. Alekseeva

    Published 2015-12-01
    “…From one textbook to another wanders the story about three (sometimes - four) Great debates, which formed the canonical history of the theory of international relations. …”
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  13. 333

    Polynomial Solutions to the Matrix Equation X−AXTB=C by Caiqin Song, Jun-e Feng

    Published 2014-01-01
    “…The provided approach does not require the coefficient matrices to be in canonical form. In addition, the numerical example is given to illustrate the effectiveness of the derived method. …”
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  14. 334

    Taking the Evolution of the Standards of Proof for a Criminal Conviction Seriously by Jacopo Della Torre

    Published 2025-01-01
    “…The first part focuses on the attempt of medieval and early modern Roman-canon systems to clarify this type of rule through a network of legal proofs. …”
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  15. 335

    A simplification functor for coalgebras by Maurice Kianpi, Celestin Nkuimi Jugnia

    Published 2006-01-01
    “…For an arbitrary-type functor F, the notion of split coalgebras, that is, coalgebras for which the canonical projections onto the simple factor split, generalizes the well-known notion of simple coalgebras. …”
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  16. 336

    A Tale of Two Travellers in King Alfred’s Court by Miguel Alarcão

    Published 2024-01-01
    “…Considering just the English medieval case, it seems reasonable to assume that some sorts or forms of travel writing, literary or otherwise, must have existed before such canonical texts as The Travels of Sir John Mandeville, the anonymous The Land of Cockaygne or Geoffrey Chaucer’s The Canterbury Tales (14th century). …”
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  17. 337

    Complete Solutions to General Box-Constrained Global Optimization Problems by Dan Wu, Youlin Shang

    Published 2011-01-01
    “…Our theorems improve and generalize recent known results in the canonical duality theory. Applications to a class of constrained optimal control problems are discussed. …”
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  18. 338

    Assessing the Capabilities of a New Linear Inversion Method for Quantitative Microwave Imaging by Loreto Di Donato, Roberta Palmeri, Gino Sorbello, Tommaso Isernia, Lorenzo Crocco

    Published 2015-01-01
    “…To this end, we carry out a parametric numerical analysis for a canonical scatterer (a homogeneous dielectric cylinder with circular cross section) and derive a quantitative criterion to foresee the method’s applicability. …”
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  19. 339

    A Convolution-Based Shearlet Transform in Free Metaplectic Domains by Tarun K. Garg, Waseem Z. Lone, Firdous A. Shah, Hatem Mejjaoli

    Published 2021-01-01
    “…The free metaplectic transformation (FMT) is a multidimensional integral transform that encompasses a broader range of integral transforms, from the classical Fourier to the more recent linear canonical transforms. The aim of this study is to introduce a novel shearlet transform by employing the free metaplectic convolution structures. …”
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  20. 340

    Gravitational Poisson brackets at null infinity compatible with smooth superrotations by Miguel Campiglia, Adarsh Sudhakar

    Published 2024-12-01
    “…In their smooth version, they can be identified with the group of diffeomorphisms on the celestial sphere. Their canonical realization requires treating the celestial metric as a variable in the gravitational phase space, along with the news and shear tensors. …”
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