Digital Gangrene: An Unusual Manifestation of Non-Hodgkin Lymphoma by Muhammad Shoaib Momen Majumder, Shamim Ahmed, Tajkia Haque, Syed Atiqul Haq, Saumitra Chakravarty, Md. Abu Shahin, Din-E-Mujahid Mohammad Faruque Osmany, Johannes J. Rasker

“…A 32-year-old male weaver had been smoking three to five cannabis-containing cigarettes daily for about ten years and methamphetamine four to five tablets daily for five years. …”
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Detection of Cannabinoid Receptor Expression by Endometriotic Lesions in Women with Endometriosis as an Alternative to Opioid-Based Pain Medication by Sarah Allam, Elizabeth Paris, Itzel Lazcano, Pincas Bitterman, Sanjib Basu, James O’Donnell, Animesh Barua

“…Emerging information suggests a potential role of medicinal cannabis in pain medication in addition to enhancing immune functions. …”
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Marijuana Compounds: A Nonconventional Approach to Parkinson’s Disease Therapy by Mariana Babayeva, Haregewein Assefa, Paramita Basu, Sanjeda Chumki, Zvi Loewy

“…Therefore, there is unmet need for more comprehensive approach in the management of PD. Cannabis and related compounds have created significant research interest as a promising therapy in neurodegenerative and movement disorders. …”
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Brief exposure to (-) THC affects zebrafish embryonic locomotion with effects that persist into the next generation by Md Ruhul Amin, Lakhan Khara, Joshua Szaszkiewicz, Andrew M. Kim, Trevor J. Hamilton, Declan W. Ali

“…Abstract Cannabis is one of the most widely used drugs, and yet an understanding of its impact on the human brain and body is inconclusive. …”
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The Use of Cannabinoids to Treat Insomnia by V. Kutniauskaitė, G. Šegždaitė, G. Žilionytė, E. Pajėdienė

“…Recently, there has been a growing interest in various cannabis preparations, particularly in cannabinoids derived from Cannabis sativa plants, for the treatment of insomnia. …”
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Commercial Cannabinoid Oil-Induced Stevens-Johnson Syndrome by Han Y. Yin, Nicholas Hadjokas, Kanish Mirchia, Robert Swan, Samuel Alpert

“…In this case, we described an unusual drug-induced SJS from a commercial, non-FDA-regulated cannabis product. The use of a commercial CBD product should be cautioned due to potential for series of drug reactions to the cannabis product and the risk for reaction to other unregulated other pharmacological components.…”
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Recurrent Nausea and Vomiting in a Pregnant Woman with Chronic Marijuana Use by Hyunyoung G. Kim, Jeremiah Moon, Heather Dixon, Paul Tullar

“…Cannabinoid hyperemesis syndrome is a condition characterized by chronic cannabis use and cyclic episodes of nausea, vomiting, and abdominal pain, relieved by compulsive bathing. …”
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Phytocannabinoids: a new frontier in Alzheimer’s disease management by Jagadeesh S. Rao

“…Individuals have utilized therapeutic cannabis-derived remedies for medicinal purposes. The cannabis plant is composed of a diverse range of phytocannabinoids, terpenes, and phenolic compounds. …”
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The Endocannabinoid System in the Postimplantation Period: A Role during Decidualization and Placentation by B. M. Fonseca, G. Correia-da-Silva, M. Almada, M. A. Costa, N. A. Teixeira

“…Although the detrimental effects of cannabis consumption during gestation are known for years, the vast majority of studies established a link between cannabis consumption and foetal development. …”
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Coming of age in recovery: The prevalence and correlates of substance use recovery status among adolescents and emerging adults. by Douglas C Smith, Crystal A Reinhart, Shahana Begum, Janaka Kosgolla, John F Kelly, Brandon B Bergman, Marni Basic

“…Outcomes included alcohol use, binge alcohol use, cannabis use, and prescription drug use in the past 30 days.…”
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A luta pelo uso da maconha medicinal no Brasil: os limites das alianças e a atuação do biopoder by Monique Batista de Oliveira

“…Em 2014, a luta de famílias pela regulamentação no Brasil do canabidiol (CBD), um dos canabinoides da cannabis sativa, trouxe força ao debate público sobre o uso medicinal na planta. …”
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A high-fat meal significantly impacts the bioavailability and biphasic absorption of cannabidiol (CBD) from a CBD-rich extract in men and women by Bo Anne Daniëlla Frederique Saals, Tessa Helena De Bie, Eral Osmanoglou, Ties van de Laar, Adriaan Willem Tuin, Anne Claire Benedikte van Orten-Luiten, Renger Frederik Witkamp

“…Abstract Cannabidiol (CBD), a specialized metabolite (phytocannabinoid) abundant in Cannabis sativa, is attracting increasing attention for its alleged health-promoting properties. …”
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Assist-linked brief intervention to reduce risky pattern of substance use in male workers employed at a tertiary care hospital in India: A randomized controlled trial by Sambhu Prasad, Debasish Basu, Surendra K. Mattoo, B. N Subodh

“…Results: The prevalence of moderate-to-high-risk use of tobacco, alcohol, and cannabis in the total sample was 28.6%, 27.5%, and 6.9%, respectively. …”
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Structural basis of THC analog activity at the Cannabinoid 1 receptor by Thor S. Thorsen, Yashraj Kulkarni, David A. Sykes, Andreas Bøggild, Taner Drace, Pattarin Hompluem, Christos Iliopoulos-Tsoutsouvas, Spyros P. Nikas, Henrik Daver, Alexandros Makriyannis, Poul Nissen, Michael Gajhede, Dmitry B. Veprintsev, Thomas Boesen, Jette S. Kastrup, David E. Gloriam

“…Abstract Tetrahydrocannabinol (THC) is the principal psychoactive compound derived from the cannabis plant Cannabis sativa and approved for emetic conditions, appetite stimulation and sleep apnea relief. …”
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Nymphaea pubescens Willd. extract and its flavonoid constituents vasodilate rat isolated pulmonary artery via NO-sGC-cGMP pathway by Teerapap Panklai, Prapapan Temkitthawon, Nungruthai Suphrom, Corine Girard, Perle Totoson, Kowit Hengphasatporn, Yasuteru Shigeta, Krongkarn Chootip, Kornkanok Ingkaninan

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Preclinical Science Regarding Cannabinoids as Analgesics: An Overview by ME Lynch

“…Modern pharmacology of cannabinoids began in 1964 with the isolation and partial synthesis of delta-9-tetrahydrocannabinol, the main psychoactive agent in herbal cannabis. Since then, potent antinociceptive and antihyperalgesic effects of cannabinoid agonists in animal models of acute and chronic pain; the presence of cannabinoid receptors in pain-processing areas of the brain, spinal cord and periphery; and evidence supporting endogenous modulation of pain systems by cannabinoids has provided support that cannabinoids exhibit significant potential as analgesics. …”
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Prevalence of posttraumatic stress disorder (PTSD) in Canada during the COVID-19 pandemic: results from the Survey on COVID-19 and Mental Health by Murray Weeks, Danielle Marion, Anne-Marie Robert, R. Nicholas Carleton

“…Factors associated with higher PTSD prevalence were female gender; younger age; lower income (females only); living in an urban area; frontline worker status or not being at work in the past week (males only); fair or poor mental health; a weak sense of community belonging; symptoms of generalized anxiety disorder and major depressive disorder; suicidal ideation; heavy alcohol use; daily cannabis use; increased alcohol and cannabis use since the start of the pandemic; decreased alcohol consumption since the start of the pandemic (males only); concerns about violence in the home; and negative impacts of the pandemic. …”
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Effective interventions to prevent youth vaping behaviours: a rapid review by Ana Paula Belon, Laura Nieuwendyk, Tasha Allen, Melissa Worrell, Candace I J Nykiforuk

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Parathyroid Paranoia: Unveiling Psychosis in Hyperparathyroidism by Rachael J. Murphy, Subin Paul, Ralph Primelo

“…Here we report the case of a 28-year-old cannabis using male with his first contact with psychiatric care because of mood instability, bizarre behavior, and poor ability to carry out activities of daily living. …”
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Impact evaluations of drug decriminalisation and legal regulation on drug use, health and social harms: a systematic review by Ayden I Scheim, Dan Werb, Nazlee Maghsoudi, Zack Marshall, Siobhan Churchill, Carolyn Ziegler

“…Most (n=104, 91.2%) were from the USA, evaluated cannabis reform (n=109, 95.6%) and focussed on legal regulation (n=96, 84.2%). 224 study outcome measures were categorised into 32 metrics, most commonly prevalence (39.5% of studies), frequency (14.0%) or perceived harmfulness (10.5%) of use of the decriminalised or regulated drug; or use of tobacco, alcohol or other drugs (12.3%). …”
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