Evaluation of the Antioxidant and Cytotoxic Activities on Cancer Cell Line of Extracts of Parasitic Plants Harvested in Tunisia by Imen Ben Attia, Paolo Zucca, Flaminia Cesare Marincola, Mariella Nieddu, Alessandra Piras, Antonella Rosa, Antonio Rescigno, Mohamed Chaieb

“…The cytotoxic effect of the oil from the parasitic plants was also studied on B16F10 melanoma cancer cells. All extracts showed antioxidant activity and differences between extracts obtained using different solvents as well as for different plants have been highlighted. …”
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Neuropilin1-dependent paracrine signaling of cancer cells mediated by miRNA exosomal cargo by Claudia Palazzo, Roberta Mastrantonio, Noemi Gioelli, Erika Testa, Francesco Recco, Donatella Lucchetti, Giulia Villari, Alessio D’Alessio, Alessandro Sgambato, Flavio Mignone, Guido Serini, Maria Teresa Viscomi, Luca Tamagnone

“…Wound healing, transwell, and digital real-time migration assays were carried out to assess the activity of cancer cell-derived exosomes in the regulation of endothelial cells. …”
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Synergistic activity of Pitstop-2 and 1,6-hexanediol in aggressive human lung cancer cells by Sílvio Terra Stefanello, Caren Rigon Mizdal, Aline Franzen da Silva, Luca Matteo Todesca, Félix Alexandre Antunes Soares, Victor Shahin

“…Abstract Metastatic cancer cells undergo metabolic reprogramming, which involves changes in the metabolic fluxes, including endocytosis, nucleocytoplasmic transport, and mitochondrial metabolism, to satisfy their massive demands for energy, cell division, and proliferation compared to normal cells. …”
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The Effects of Microseconds Electroporation on Pore Size, Viability and Mitochondrial Membrane Potential of Cervical Cancer Cells by Güney GÜRSOY, Meriç Arda ESMEKAYA, Zehra ÇİÇEK

“…Conclusion: In conclusion, our study showed that the application of EP to the cervical cancer cell line resulted in the formation of pores of varying sizes on the membrane. …”
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Unveiling the benefit of germinated colored rice extract to decrease metastatic potential of colorectal cancer cells by Kittirat Saharat, Natthaphorn Paramee, N. Monique Paricharttanakul, Nuchanart Rangkadilok, Daranee Chokchaichamnankit, Chantragan Srisomsap, Kriengsak Lirdprapamongkol, Jisnuson Svasti, Jutamaad Satayavivad

“…Metastasis, namely the spread of cancer cells to distant sites in the body, is a serious problem for cancer therapy. …”
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Cytotoxic activity of Fomitopsis betulina against normal and cancer cells – a comprehensive literature review by Paulina Nowotarska, Maciej Janeczek, Benita Wiatrak

“…The aim of this paper is to systematically review the literature on the cytotoxic effects of Fomitopsis betulina on normal and cancer cell lines. The review was conducted by searching PubMed, Google Scholar, and Web of Science databases up to July 2024, using specific MeSH terms and keywords related to cytotoxicity, cancer cells, and normal cells. …”
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Antitumor Activity of Intratumoral Ethanol Injection in an Orthotopic Pancreatic Cancer Cell Mouse Xenograft Model by Wen-Ying Zhang, Zhen-Dong Jin, Feng Liu, Hai-Hua Yuan, Bin Jiang

“…The subcutaneous and orthotopic human pancreatic cancer cell mouse xenograft models were established. …”
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Modification-specific Proteomic Analysis Reveals Cysteine S‑Palmitoylation Involved in Esophageal Cancer Cell Radiation by Qingtao Ni, Chi Pan, Gaohua Han

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Multilevel plasticity and altered glycosylation drive aggressiveness in hypoxic and glucose-deprived bladder cancer cells by Andreia Peixoto, Dylan Ferreira, Andreia Miranda, Marta Relvas-Santos, Rui Freitas, Tim S. Veth, Andreia Brandão, Eduardo Ferreira, Paula Paulo, Marta Cardoso, Cristiana Gaiteiro, Sofia Cotton, Janine Soares, Luís Lima, Filipe Teixeira, Rita Ferreira, Carlos Palmeira, Albert J.R. Heck, Maria José Oliveira, André M.N. Silva, Lúcio Lara Santos, José Alexandre Ferreira

“…Employing a multi-omics approach, we discovered that hypoxic and glucose-deprived cancer cells enter a quiescent state supported by mitophagy, fatty acid β-oxidation, and amino acid catabolism, concurrently enhancing their invasive capabilities. …”
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Lithium-Acetate-Mediated Biginelli One-Pot Multicomponent Synthesis under Solvent-Free Conditions and Cytotoxic Activity against the Human Lung Cancer Cell Line A549 and Breast Cancer Cell Line MCF7 by Harshita Sachdeva, Diksha Dwivedi

“…The prepared compounds are evaluated for anticancer activity against two human cancer cell lines (lung cancer cell line A549 and breast cancer cell line MCF7).…”
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Pharmacological activity of OST-01, a natural product from baccharis coridifolia, on breast cancer cells by HyunJun Kang, Dinh Hoa Hoang, Melissa Valerio, Khyatiben Pathak, William Graff, Alexis LeVee, Jun Wu, Mark A. LaBarge, David Frankhouser, Russell C. Rockne, Patrick Pirrotte, Bin Zhang, Joanne Mortimer, Le Xuan Truong Nguyen, Guido Marcucci

“…Herein we first report on the anticancer activity OST-01, a natural product from Baccharis Coridifolia, on breast cancer cells, including triple-negative breast cancer (TNBC). …”
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Escin Chemosensitizes Human Pancreatic Cancer Cells and Inhibits the Nuclear Factor-kappaB Signaling Pathway by A. Rimmon, A. Vexler, L. Berkovich, G. Earon, I. Ron, S. Lev-Ari

“…Escin decreased pancreatic cancer cell survival, induced apoptosis, and downregulated NF-κB signaling pathway. …”
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The extract of the immature fruit of Poncirus trifoliata induces apoptosis in colorectal cancer cells via mitochondrial autophagy by Sun-Young Kim, Ho-Keun Yi, Bong-Sik Yun, Dae-Yeol Lee, Pyung Han Hwang, Hae-Ryong Park, Min Sun Kim

“…However, their effect on colon cancer cells remains unclear. We investigated the effect of the immature fruit of P. trifoliate extract on colorectal adenocarcinoma. …”
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Ginseng-derived Nanoparticles Inhibit Lung Cancer Cell Growth by Promoting Macrophage M1 Polarization by Liangliang FAN, Limei REN, Song YANG, Wenjing LI, Yueming ZHAO, Ronghua ZHAO, Daqing ZHAO, Jiawen WANG

Subjects: “…human non-small cell lung cancer cells…”
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Position in proton Bragg curve influences DNA damage complexity and survival in head and neck cancer cells by Tim Heemskerk, Celebrity Groenendijk, Marta Rovituso, Ernst van der Wal, Wouter van Burik, Konstantinos Chatzipapas, Danny Lathouwers, Roland Kanaar, Jeremy M.C. Brown, Jeroen Essers

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Poly lactic‐co‐glycolic acid‐alginate nanocarrier for efficient drug delivery to liver cancer cells by Mahsa Hoseinzadeh, Mohammad Javad Mokhtari, Farshid Kafilzadeh, Javad Mohammadnejad, Yaghoob Taheri

“…About 12% and 10% cell viabilities were observed in HepG2 and Huh7 cancer cells after 24 h treatment with 400 nM concentration of FA‐PLGA‐Dox‐Alg nanocarrier respectively. …”
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Obtaining a pancreatic cancer cell line stably expressing doxycycline-dependent endonuclease Cas9 by A.K. Nurgalieva, V.S. Skripova, L.F. Minigulova, R.G. Kiyamova

“…The aim of this work is modification of the pancreatic cancer cell line MIA PaCa-2 to express a doxycycline-inducible Cas9 endonuclease gene. …”
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Decreased Autophagic Activity in Triple-Negative Breast Cancer Cells upon Hydroxychloroquine and Thymoquinone Combination Treatment by Tuğcan Korak, Merve Gulsen Bal Albayrak, Sevinc Yanar, Gürler Akpınar, Murat Kasap

“…In this study, we investigated the potential anti-cancer and autophagy-modulating effects of hydroxychloroquine-thymoquinone combination on triple-negative breast cancer cells in vitro.Material and Method: The viability of MDA-MB-231 cells was evaluated after treatment with hydroxychloroquine (10-210 µM) and thymoquinone (5-45 µM) for 24 and 48 hours using the WST-1 assay. …”
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Secretory mitophagy: an extracellular vesicle-mediated adaptive mechanism for cancer cell survival under oxidative stress by Purva V. Gade, Angela Victoria Rojas Rivera, Layla Hasanzadah, Sofie Strompf, Thomas Raymond Philipson, Matthew Gadziala, Atharva Tyagi, Arnav Bandam, Rithvik Gabbireddy, Fatah Kashanchi, Amanda Haymond, Lance A. Liotta, Marissa A. Howard

“…Our data supports the hypothesis that secretory mitophagy is a previously unexplored process by which cancer cells adapt to survive therapeutic or hypoxic stress. …”
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Targeting heparan sulfate proteoglycans as an effective strategy for inhibiting cancer cell migration and invasiveness compared to heparin by Lorenzo Depau, Jlenia Brunetti, Chiara Falciani, Elisabetta Mandarini, Marta Zanchi, Maria Francesca Paolocci, Marta Garfì, Alessandro Pini, Luisa Bracci

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