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Chlamydia trachomatis Growth and Cytokine mRNA Response in a Prostate Cancer Cell Line
Published 2019-01-01“…The possible roles of reactive oxygen species and impaired mitochondrial oxidation in the prostate cancer cell line are discussed as factors promoting the early stages of C. trachomatis growth in CWR-R1 cells.…”
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102
Mycobacterium bovis Bacillus Calmette-Guérin-Induced Macrophage Cytotoxicity against Bladder Cancer Cells
Published 2010-01-01“…This review summarizes the current understanding of the BCG-induced macrophage cytotoxicity toward bladder cancer cells with an intention to inspire investigation on this important but underdeveloped research field.…”
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103
Z-Guggulsterone Induces Apoptosis in Gastric Cancer Cells through the Intrinsic Mitochondria-Dependent Pathway
Published 2021-01-01“…To study the effects of z-guggulsterone on gastric cancer cell apoptosis and the mechanism related. Materials and Methods. …”
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104
Metabolic consequences of erastin-induced ferroptosis in human ovarian cancer cells: an untargeted metabolomics study
Published 2025-01-01“…Erastin (ER), a ferroptosis inducer, kills tumor cells by generating and accumulating reactive oxygen species (ROS) within the cell, resulting in an iron-dependent oxidative damage-mediated ferroptotic cell death.MethodsWe have utilized human ovarian cancer cell lines, OVCAR-8 and its adriamycin-selected, multi-drug resistance protein (MDR1)-expressing NCI/ADR-RES, both equally sensitive to ER, to identify metabolic biomarkers of ferroptosis.ResultsOur studies showed that ER treatment rapidly depleted cellular glutathione and cysteine and enhanced formation of ophthalamate (OPH) in both cells. …”
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105
The Transcription Factor Creb is Involved in Sorafenib-Inhibited Renal Cancer Cell Proliferation, Migration and Invasion
Published 2018-12-01“…Renal cancer cells were cultured in medium containing sorafenib for 12, 24, 48 and 72 h. …”
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106
Mitochondrial Complex I Inhibitors and Forced Oxidative Phosphorylation Synergize in Inducing Cancer Cell Death
Published 2013-01-01“…Cancer cells generally rely mostly on glycolysis rather than oxidative phosphorylation (OXPHOS) for ATP production. …”
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107
Reduced-graphene oxide (R-GO) conjugated methotrexate (MTX) killing of oral cancer cells
Published 2024-06-01Get full text
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108
Synthetic augmentation of cancer cell line multi-omic datasets using unsupervised deep learning
Published 2024-11-01“…Harnessing orthogonal multi-omic information, this model successfully generates molecular and phenotypic profiles, resulting in an increase of 32.7% in the number of multi-omic profiles and thereby generating a complete DepMap for 1523 cancer cell lines. The synthetically enhanced data increases statistical power, uncovering less studied mechanisms associated with drug resistance, and refines the identification of genetic associations and clustering of cancer cell lines. …”
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109
Chladni and Fractal Dynamics: Dual Mode Marker to Map Cancer Cell Nucleus Disintegration Phases
Published 2024-12-01“…We identified and mapped five key phase transitions that ultimately lead to the breakdown of cancer cell nuclei.…”
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SLC7A5 is required for cancer cell growth under arginine-limited conditions
Published 2025-01-01“…Pharmacological inhibition of SLC7A5 blocks growth under low-arginine conditions across a diverse group of cancer cell lines. Loss of SLC7A5 reduces tumor growth and citrulline import in a mouse tumor model. …”
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Sempervirine inhibits proliferation, invasion and metastasis of ovarian cancer cells and induces ultrastructural changes in vivo
Published 2025-01-01“…CCK8 assays showed that sempervirine dose-dependently inhibited the proliferation of SKOV3 ovarian cancer cells. Transwell assays demonstrated that sempervirine significantly suppressed the invasion and metastasis of SKOV3 cells. …”
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114
Xanthoxyletin blocks the RANK/RANKL signaling pathway to suppress the growth of human pancreatic cancer cells
Published 2023-09-01“…Nonetheless, the anticancer effects of xanthoxyletin against human pancreatic cancer cells have not been evaluated. Against this backdrop, the present study was designed to evaluate the anticancer effects of xanthoxyletin in human pancreatic cancer cells and to decipher the underlying molecular mechanisms. …”
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115
Cancer cells avoid ferroptosis induced by immune cells via fatty acid binding proteins
Published 2025-02-01“…However, the mechanisms by which cancer cells avoid immunotherapy-mediated ferroptosis are unclear. …”
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116
Methyltransferase DNMT3B promotes colorectal cancer cell proliferation by inhibiting PLCG2
Published 2024-08-01“…Its role in colorectal cancer cells is still unknown. In this study, qRT-PCR is used to measure DNMT3B expression in colorectal cancer. …”
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117
Curcumin Inhibits Papillary Thyroid Cancer Cell Proliferation by Regulating lncRNA LINC00691
Published 2022-01-01Get full text
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118
N6‐Methyladenosine Regulates Cilia Elongation in Cancer Cells by Modulating HDAC6 Expression
Published 2025-01-01“…Here, the results show that m6A methyltransferase METTL3 regulates cilia length in cancer cells via HDAC6‐dependent deacetylation of axonemal α‐tubulin, thereby controlling cancer development. …”
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119
Design and Bulk Sensitivity Analysis of a Silicon Nitride Photonic Biosensor for Cancer Cell Detection
Published 2022-01-01“…The silicon nitride (SiN4) Mach–Zehnder interferometer utilizes the refractive index of different cancer cells (1.39–1.401) to determine the bulk sensitivity. …”
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120
Proton pump inhibitors enhance chemosensitivity, promote apoptosis, and suppress migration of breast cancer cells
Published 2020-06-01“…In this study, the anti-proliferative and anti-migratory effects of PPIs in three breast cancer cell lines; MCF-7, T47D, and MDA-MB-231 cells, have been investigated. …”
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